Search results for "Trial"

Le lettere crescono nel giardino dell'attività umana

2017

Nutro molto rispetto per chi si occupa di tipografia, a qualsiasi livello lo faccia, come attività progettuale, come ambito di ricerca, come materia di insegnamento. Trovo che sia una disciplina che richiede un lavoro importante, silenzioso, metodico, una attenta dedizione, che impone di studiare la forma delle lettere, osservando i tanti piccoli segni a distanze differenti, come in un processo di avvicinamento a un territorio, in cui gli elementi possono apparire brancolanti sul bianco del foglio come lupi su una distesa di neve, oppure serrati come soldati in ranghi di un esercito ordinato su una superficie occupata.

Honey Bee Pollen in Meagre (Argyrosomus regius) Juvenile Diets: Effects on Growth, Diet Digestibility, Intestinal Traits, and Biochemical Markers Rel…

2020

This research aimed to evaluate the effects of the inclusion of honey bee pollen (HBP) in meagre (Argyrosoumus regius) juveniles&rsquo

The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols i…

2020

Background: Gilles de la Tourette syndrome (TS) is a chronic neuropsychiatric disorder characterized by motor and vocal tics. First-line treatments for tics are antipsychotics and tic-specific behavioral therapies. However, due to a lack of trained therapists and adverse events of antipsychotic medication many patients seek alternative treatment options including cannabis. Based on the favorable results obtained from case studies on different cannabis-based medicines as well as two small randomized controlled trials using delta-9-tetrahydrocannabinol (THC), we hypothesize that the cannabis extract nabiximols can be regarded as a promising new and safe treatment strategy in TS.Objective: To …

Open Service Innovation: The Case of Tourism Firms in Scandinavia

2016

Most empirical research investigating open innovation has focused on the development of new physical products in manufacturing industries, whereas open service innovation has not been researched correspondingly. Services have some characteristics that distinguish them from physical products, which may affect the types of open innovation practice utilised during service innovation processes. Tourism services comprise a subset of services that is particularly distant from tangible products. Therefore, the exploration of how tourism firms utilise different types of open innovation practice offers a valuable opportunity to learn about the nature of open service innovation practices. Thus, this …

Configurational theory in traditional manufacturing industries: a new model of high-performing small and medium-sized enterprises

2020

The goal of this study is to provide a model of high-performing small and medium-sized companies to address the new environmental challenges in traditional manufacturing industries. Adopting a configurational logic and following an inductive approach based on four high-performing firms, this paper provides new empirical evidence on how the steps followed by these firms are adjusted to the high-performance models prescribed by the literature. In doing so, it also offers a dynamic view of the interrelationships between the strategy and the new conditions of the environment. At a practitioner level, the paper illustrates which recipes are more appropriate to prescribe recommendations for a mor…

An Entropy-Driven Scenario for Future Design Education

2021

In a Domus article published in 1998, John Thackara claimed that design would lead by entropy in the future, and he won- dered how to avoid a similar dystopian scenario. As designers, we are aware of how wicked problems are really hard to face and how complexity has increased in these past decades: trans- disciplinary skills are therefore increasingly required. Further- more, we can only achieve incremental improvements to the situation, because a wicked problem typically has no definitive solution (Rittel, Webber 1973, in Erlhoff, 2008): a new mind- set is therefore required, one that is capable of overcoming our traditional one (Morin, 2015), in order to face and manage the complexity. In…

Longitudinal Gait Analysis of a Transfemoral Amputee Patient: Single-Case Report from Socket-Type to Osseointegrated Prosthesis

2023

The aim of the present case report was to provide a longitudinal functional assessment of a patient with transfemoral amputation from the preoperative status with socket-type prosthesis to one year after the osseointegration surgery. A 44 years-old male patient was scheduled for osseointegration surgery 17 years after transfemoral amputation. Gait analysis was performed through 15 wearable inertial sensors (MTw Awinda, Xsens) before surgery (patient wearing his standard socket-type prosthesis) and at 3-, 6-, and 12-month follow-ups after osseointegration. ANOVA in Statistical Parametric Mapping was used to assess the changes in amputee and sound limb hip and pelvis kinematics. The gait symm…

Analisi del transitorio termico nei processi di surgelazione di derrate alimentari

2010

A two-phase insertion technique of unexpected customers for a dynamic dial-a-ride problem

2006

Abstract This work deals with a dynamic dial-a-ride problem with time window constraints. In particular, new unplanned requests for service may arise at a vehicle stop and the driver must decide in real-time whether to accept or reject them. For this problem, we have developed a two-phase insertion algorithm based on route perturbations: the first phase, which is run off-line when the vehicle moves between two successive stops, aims at creating a feasible neighborhood of the current route; while the second phase, which is run in real-time every time a new request occurs, inserts, when possible, the delivery stop of the new customer in the current route.

Minimizing fleet operating costs for a container transportation company

2006

Abstract This paper focuses on a fleet management problem that arises in container trucking industry. From the container transportation company perspective, the present and future operating costs to minimize can be divided in three components: the routing costs, the resource (i.e., driver and truck) assignment costs and the container repositioning costs (i.e., the costs of restoring a given container fleet distribution over the serviced territory, as requested by the shippers that own the containers). This real-world problem has been modeled as an integer programming problem. The proposed solution approach is based on the decomposition of this problem in three simpler sub-problems associate…