Search results for "Type 2"

showing 10 items of 1034 documents

The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe. The Euro Heart Survey on diabetes and the heart.

2004

Aim The objective behind the Euro Heart Survey on diabetes and the heart was to study the prevalence of abnormal glucose regulation in adult patients with coronary artery disease (CAD). Methods and results The survey engaged 110 centres in 25 countries recruiting 4196 patients referred to a cardiologist due to CAD out of whom 2107 were admitted on an acute basis and 2854 had an elective consultation. Patient data were collected via a web-based case record form. An oral glucose tolerance test (OGTT) was used for the characterisation of the glucose metabolism. Thirty-one per cent of the patients had diabetes. An OGTT was performed on the 1920 patients without known diabetes, of whom 923 had a…

AdultBlood GlucoseMaleDiabetes mellitumedicine.medical_specialtyAbnormal glucoseDiabetic AngiopathieOral glucose tolerance testCoronary Artery DiseaseImpaired glucose toleranceCoronary artery diseaseSDG 3 - Good Health and Well-beingRisk FactorsDiabetes mellitusInternal medicineEpidemiologymedicineHumansIn patientAgedGlucose tolerance testmedicine.diagnostic_testbusiness.industryImpaired glucose toleranceGlucose Tolerance TestMiddle Agedmedicine.diseaseSurgeryEuropeDiabetes Mellitus Type 2Blood sugar regulationFemaleCardiology and Cardiovascular MedicinebusinessDiabetic AngiopathiesHumanEuropean heart journal
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Attitudes towards insulin initiation in type 2 diabetes patients among healthcare providers: A survey research

2016

Aims: To describe the views of healthcare providers about starting insulin in patients with type 2 diabetes and to determine the specific factors that contribute to delay insulin initiation. Methods: Two-phases observational descriptive study. In the quantitative phase we conducted a cross-sectional survey of a sample of 380 healthcare professionals (general practitioners (GPs), endocrinologists, internists and nurses). In the qualitative phase, a discussion group reviewed the results of the survey to propose solutions. Results: In poorly controlled patients, 46% of GPs vs. 43.2% of internists and 31.3% of endocrinologists waited 3-6 months before starting insulin, and 71.4% of GPs vs. 66.7…

AdultBlood GlucoseMaleHealth Knowledge Attitudes Practicemedicine.medical_specialtyTime FactorsAttitude of Health PersonnelHealth PersonnelEndocrinology Diabetes and Metabolismmedicine.medical_treatmenteducation030209 endocrinology & metabolismTime-to-treatmentsType 2 diabetes03 medical and health sciencesDiabetes mellitus0302 clinical medicineEndocrinologySurveys and QuestionnairesDiabetes mellitusInternal medicineDisease managementInternal MedicineHumansInsulinMedicine030212 general & internal medicinePractice Patterns Physicians'Disease management (health)Glycemicbusiness.industryInsulinGeneral MedicineMiddle Agedmedicine.diseaseCross-Sectional StudiesEndocrinologyDiabetes Mellitus Type 2Basal (medicine)SpainFamily medicineFemaleObservational studyGeneral practicebusinessHealthcare providersType 2Diabetes Research and Clinical Practice
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Study protocol of the Diabetes and Depression Study (DAD): a multi-center randomized controlled trial to compare the efficacy of a diabetes-specific …

2013

Background Depression is common in diabetes and associated with hyperglycemia, diabetes related complications and mortality. No single intervention has been identified that consistently leads to simultaneous improvement of depression and glycemic control. Our aim is to analyze the efficacy of a diabetes-specific cognitive behavioral group therapy (CBT) compared to sertraline (SER) in adults with depression and poorly controlled diabetes. Methods/Design This study is a multi-center parallel arm randomized controlled trial currently in its data analysis phase. We included 251 patients in 70 secondary care centers across Germany. Key inclusion criteria were: type 1 or 2 diabetes, major depress…

AdultBlood GlucoseMaleResearch designmedicine.medical_specialtymedicine.medical_treatmentlaw.inventionGroup psychotherapyStudy ProtocolYoung AdultCognitionClinical ProtocolsRandomized controlled triallawGermanySertralineInternal medicineDiabetes mellitusHumansMedicineYoung adultPsychiatryDepression (differential diagnoses)AgedGlycemicGlycated HemoglobinDepressive Disorder MajorSertralineCognitive Behavioral Therapybusiness.industryMiddle Agedmedicine.diseaseAntidepressive AgentsPsychiatry and Mental healthDiabetes Mellitus Type 1Treatment OutcomeDiabetes Mellitus Type 2Research DesignPsychotherapy GroupFemalebusinessmedicine.drugBMC Psychiatry
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Pasta consumption and connected dietary habits: Associations with glucose control, adiposity measures, and cardiovascular risk factors in people with…

2019

Background: Pasta is a refined carbohydrate with a low glycemic index. Whether pasta shares the metabolic advantages of other low glycemic index foods has not really been investigated. The aim of this study is to document, in people with type-2 diabetes, the consumption of pasta, the connected dietary habits, and the association with glucose control, measures of adiposity, and major cardiovascular risk factors. Methods: We studied 2562 participants. The dietary habits were assessed with the European Prospective Investigation into Cancer and Nutrition (EPIC) questionnaire. Sex-specific quartiles of pasta consumption were created in order to explore the study aims. Results: A higher pasta con…

AdultBlood GlucoseMalecardiovascular risk factorsAdolescentSaturated fatlcsh:TX341-641Type 2 diabetesAdded sugarDietary habitCardiovascular risk factorArticleSettore MED/13 - EndocrinologiaYoung AdultEnvironmental healthDiabetes mellitusGlucose controlmedicinebody mass index; cardiovascular risk factors; dietary habits; glucose control; pasta consumption; type 2 diabetesDietary CarbohydratesHumansHypoglycemic AgentsChilddietary habitsBody mass indexAdiposityAgedNutrition and Dieteticsbusiness.industryPasta consumptionConfoundingfood and beveragesType 2 diabetesFeeding BehaviorMiddle Agedmedicine.diseaseObesityEuropean Prospective Investigation into Cancer and NutritionDiabetes Mellitus Type 2ItalyCardiovascular DiseasesChild PreschoolFemalebusinessBody mass indexlcsh:Nutrition. Foods and food supplyFood Science
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Correlation between different degree and duration of metabolic control and thyroid hormone levels in type 1 and type 2 diabetics.

1983

Thyroxine (T4), triiodothyronine (T3), reverse T3 (rT3) and HbA1c were assayed in 21 insulin-dependent (type 1) diabetics and in 45 non-insulin-dependent (type 2) diabetics with normal thyroid function and different levels of control, and were compared to values found in apparently healthy controls. rT3 and rT3/T3 ratio were significantly increased both in type 1 and type 2 diabetics. T3 and T4 were significantly lower in type 2 diabetics than in the controls. Significant positive correlations of HbA1c to rT3 (r = 0.63) and to rT3/T3 ratio (r = 0.53) were found in type 1, and in type 2 diabetics (HbA1c, rT3-r = 0.50), (HbA1c, rT3/T3-r = 0.37). There was no correlation between glycemia (BG),…

AdultBlood GlucoseMaleendocrine systemmedicine.medical_specialtyThyroid Hormonesendocrine system diseasesAdolescentTriiodothyronine ReverseEndocrinology Diabetes and MetabolismCorrelationEndocrinologyDiabetes mellitusInternal medicineInternal MedicinemedicineHumansAgedGlycated HemoglobinTriiodothyroninebusiness.industryThyroidType 2 Diabetes MellitusGeneral MedicineMiddle Agedmedicine.diseaseThyroxinemedicine.anatomical_structureEndocrinologyDiabetes Mellitus Type 1Diabetes Mellitus Type 2Thyroid hormonesMetabolic control analysisTriiodothyronineFemalebusinesshormones hormone substitutes and hormone antagonistsHormoneActa diabetologica latina
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Clinical profiles and quality of care of subjects with type 2 diabetes according to their cardiovascular risk: an observational, retrospective study

2021

Abstract Background The European Society of Cardiology (ESC) recently defined cardiovascular risk classes for subjects with diabetes. Aim of this study was to explore the distribution of subjects with type 2 diabetes (T2D) by cardiovascular risk groups according to the ESC classification and to describe the quality indicators of care, with particular regard to cardiovascular risk factors. Methods The study is based on data extracted from electronic medical records of patients treated at the 258 Italian diabetes centers participating in the AMD Annals initiative. Patients with T2D were stratified by cardiovascular risk. General descriptive indicators, measures of intermediate outcomes, inten…

AdultBlood GlucoseMalelcsh:Diseases of the circulatory (Cardiovascular) systemmedicine.medical_specialtyTime FactorsEndocrinology Diabetes and MetabolismType 2 diabetesIncretinsRisk AssessmentDiabetes mellitusInternal medicinemedicineElectronic Health RecordsHumansHypoglycemic AgentsMedical prescriptionSodium-Glucose Transporter 2 InhibitorsOriginal InvestigationAgedQuality Indicators Health CareRetrospective StudiesAngiologyCardiovascular risk Humans Hypoglycemic Agents Incretins Italy Male Middle Aged Retrospective Studies Risk Assessment Sodium-Glucose Transporter 2 Inhibitors Time Factors Treatment Outcome Quality Indicators Health Care Quality of care Type 2 diabetes Adult Aged Aged 80 and over Biomarkers Blood Glucose Cardiovascular Diseases Diabetes Mellitus Type 2 Dipeptidyl-Peptidase IV Inhibitors Heart Disease Risk Factors Female Electronic Health RecordsAged 80 and overDipeptidyl-Peptidase IV Inhibitorsbusiness.industryMedical recordQuality of careType 2 diabetesRetrospective cohort studyMiddle AgedCardiovascular riskmedicine.diseaseTreatment OutcomeDiabetes Mellitus Type 2ItalyCardiovascular DiseasesHeart Disease Risk Factorslcsh:RC666-701AlbuminuriaFemaleObservational studymedicine.symptomCardiology and Cardiovascular MedicinebusinessBiomarkersCardiovascular Diabetology
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Red Cell Membrane Protein Lateral Mobility in Diabetes Mellitus

1992

In a group of 24 diabetics subdivided for type, we evaluated the red cell membrane protein lateral mobility marking intact red cells with pyrene-3-maleimide (3-PM) and calculating the dimer to monomer fluorescence intensity ratio (Iex/Im). The same fluorescent parameter was determined in a group of 13 normal controls. From the obtained data, it is evident that the red cell membrane protein lateral mobility clearly discriminates normals from diabetics of type 1 and 2. In normals and in diabetics of type 1 and 2 no relationship is present between this fluorescent determinant and the glycometabolic parameters (FBGL and HbA1c); considering all the diabetics, a negative relationship is evident b…

AdultBlood GlucoseMalemedicine.medical_specialtyAdolescentEndocrinology Diabetes and MetabolismDimerClinical BiochemistryBiologyBiochemistryBlood cellchemistry.chemical_compoundEndocrinologyInternal medicineDiabetes mellitusDiabetes MellitusmedicineHumansChildAgedGlycated HemoglobinErythrocyte MembraneBiochemistry (medical)Membrane ProteinsGeneral MedicineMiddle Agedmedicine.diseaseFluorescenceRed cell membraneFluorescence intensityRed blood cellDiabetes Mellitus Type 1Endocrinologymedicine.anatomical_structureDiabetes Mellitus Type 2Membrane proteinchemistryFemaleHormone and Metabolic Research
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Are general practitioners characteristics associated with the quality of type 2 diabetes care in general practice? Results from the Norwegian ROSA4 s…

2018

Abstract Objective: To explore the associations between general practitioners (GPs) characteristics such as gender, specialist status, country of birth and country of graduation and the quality of care for patients with type 2 diabetes (T2DM). Design: Cross-sectional survey. Setting and subjects: The 277 GPs provided care for 10082 patients with T2DM in Norway in 2014. The GPs characteristics were self-reported: 55% were male, 68% were specialists in General Practice, 82% born in Norway and 87% had graduated in Western Europe. Of patients, 81% were born in Norway and 8% in South Asia. Data regarding diabetes care were obtained from electronic medical records and manually verified. Main outc…

AdultBlood GlucoseMalemedicine.medical_specialtyAsiaCross-sectional studyGeneral PracticeEthnic groupBlood PressureNorwegian030204 cardiovascular system & hematology03 medical and health sciencesspecializationfamily medicine0302 clinical medicineGeneral Practitionersquality of careEthnicitymedicinegenderHumans030212 general & internal medicinePractice Patterns Physicians'Screening proceduresQuality of Health CareGlycated HemoglobinNorwaybusiness.industrylcsh:Public aspects of medicineMedical recordPublic Health Environmental and Occupational Healthlcsh:RA1-1270Type 2 diabetesMiddle Agedlanguage.human_languagePeer reviewEuropeCross-Sectional StudiesDiabetes Mellitus Type 2Family medicinegeneral practitionerlanguageGlobal Positioning SystemFemaleGuideline AdherencebusinessResearch ArticleGraduation
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Once-Daily Liraglutide Versus Lixisenatide as Add-on to Metformin in Type 2 Diabetes: A 26-Week Randomized Controlled Clinical Trial

2016

OBJECTIVE To compare the efficacy and safety of liraglutide versus lixisenatide as add-on to metformin in patients with type 2 diabetes not achieving adequate glycemic control on metformin alone. RESEARCH DESIGN AND METHODS In this 26-week, randomized, parallel-group, open-label trial, 404 patients were randomized 1:1 to liraglutide 1.8 mg or lixisenatide 20 µg as add-on to metformin. Liraglutide was administered once daily at any time of the day. Lixisenatide was administered once daily within 1 h prior to the morning or evening meal. RESULTS At week 26, liraglutide reduced HbA1c (primary end point) more than lixisenatide (estimated treatment difference −0.62% [95% CI −0.8; −0.4]; P &…

AdultBlood GlucoseMalemedicine.medical_specialtyEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismType 2 diabetes030204 cardiovascular system & hematologyHypoglycemiaDrug Administration Schedulelaw.inventionYoung Adult03 medical and health sciencesLixisenatidechemistry.chemical_compound0302 clinical medicineRandomized controlled triallawInternal medicineInternal MedicinemedicineClinical endpointHumansHypoglycemic AgentsAgedGlycemicAged 80 and overGlycated HemoglobinAdvanced and Specialized NursingLiraglutidebusiness.industryBody WeightLiraglutideMiddle AgedPostprandial Periodmedicine.diseaseHypoglycemiaMetforminMetforminTreatment OutcomeEndocrinologyDiabetes Mellitus Type 2chemistryDrug Therapy CombinationFemalePeptidesbusinessmedicine.drugDiabetes Care
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Circulating Apelin is increased in patients with type 1 or type 2 diabetes and is associated with better glycaemic control

2013

SummaryContext Apelin is an adipokine expressed in several tissues and it appears to be involved in energy metabolism. Objective The aim of this study was to determine serum apelin levels in a large cohort of patients with type 1 and type 2 diabetes and control subjects and to correlate the results with glycaemic control. Design and Participants One hundred and thirty patients with type 1 diabetes, 98 patients with type 2 diabetes and 162 controls were enrolled in the study. Apelin levels were measured by enzyme-linked immunosorbent assay. Results Serum apelin levels were significantly higher in type 1 and type 2 diabetic patients than in controls (P < 0·0001). Serum apelin levels were high…

AdultBlood GlucoseMalemedicine.medical_specialtyEndocrinology Diabetes and MetabolismAdipokineType 2 diabetesEndocrinologyInsulin resistanceInternal medicineDiabetes mellitusmedicineHumansAgedGlycated HemoglobinType 1 diabetesbusiness.industryCase-control studyMiddle Agedmedicine.diseaseObesityUp-RegulationApelinDiabetes Mellitus Type 1EndocrinologyDiabetes Mellitus Type 2Case-Control StudiesApelinIntercellular Signaling Peptides and ProteinsFemaleInsulin ResistancebusinessBiomarkersClinical Endocrinology
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