Search results for "UI"

showing 10 items of 43725 documents

The chemical composition of the aerial parts essential oil of Achillea cretica L. (Asteraceae) growing wild in Crete (Greece)

2022

Achillea cretica (L.) (Asteraceae) is a suffruticosa camefite plant, mainly distributed in Crete, Aegean Islands, and eastern Mediterranean area. In the present study, the chemical composition of the essential oil from aerial parts of a not previously investigated accession of Achillea cretica, collected in Crete, was analysed by GC-MS. The results showed the presence of large quantity of α-bisabolol (53.88%) followed by the related compound α-bisabolol-oxide (2.76%), and spathulenol (5.94%). Based on the composition of the essential oils of all the other Achillea taxa, several consideration have been carried out.

α-bisabololAchillea creticasesquiterpenesOrganic ChemistryPlant ScienceAsteraceaeBiochemistryessential oilAnalytical ChemistryNatural Product Research
researchProduct

α-Conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors

2003

The Xenopus laevis oocyte expression system was used to determine the activities of alpha-conotoxins EpI and the ribbon isomer of AuIB, on defined nicotinic acetylcholine receptors (nAChRs). In contrast to previous findings on intracardiac ganglion neurones, alpha-EpI showed no significant activity on oocyte-expressed alpha3beta4 and alpha3beta2 nAChRs but blocked the alpha7 nAChR with an IC50 value of 30 nM. A similar IC50 value (103 nM) was obtained on the alpha7/5HT3 chimeric receptor stably expressed in mammalian cells. Ribbon AuIB maintained its selectivity on oocyte-expressed alpha3beta4 receptors but unlike in native cells, where it was 10-fold more potent than native alpha-AuIB, had…

α7 nicotinic acetylcholine receptorα-Conotoxin AuIBRecombinant Fusion ProteinsBiophysicsXenopusNicotinic AntagonistsReceptors NicotinicPharmacologyTransfectionBiochemistrycomplex mixturesSubstrate SpecificityInhibitory Concentration 50Xenopus laevisStructural BiologyGeneticsmedicineAnimalsConotoxinNicotinic AntagonistReceptorMolecular BiologyAcetylcholine receptorbiologyα-Conotoxin EpICell Biologybiology.organism_classificationRatsCell biologyProtein SubunitsNicotinic acetylcholine receptorNicotinic agonistnervous systemIntracardiac gangliaOocytessense organsReceptors Serotonin 5-HT3ConotoxinsAcetylcholineXenopus laevis oocytemedicine.drugFEBS Letters
researchProduct

Characterization and antimicrobial activity of the volatile components of the flowers of Magydaris tomentosa (Desf.) DC. collected in Sicily and Alge…

2014

The essential oils of the flowers of Magydaris tomentosa (Desf.) DC. (Apiaceae) collected in Sicily (MSi) and Algeria (MAl), respectively, were obtained by hydrodistillation, and their compositions were analysed. The analyses allowed the identification and quantification of 23 components in MSi and 60 compounds in MAl, respectively, showing a very different profile in the composition of the two populations. The main components of MSi were cembrene (28.2%), α-springene (17.5%) and β-springene (14.8%), also present in MAl but in lesser amount (0.4%, 1.8% and 0.9%, respectively), whereas the principal constituents of MAl were (E)-nerolidol (35.4%), α-costol (13.3%) and β-costol (6.8%). Both MS…

β-springeneFlowersMicrobial Sensitivity TestsPlant ScienceBiochemistryMagydaris tomentosaGas Chromatography-Mass Spectrometryessential oilAnalytical ChemistryAnti-Infective Agentsα\-springeneStaphylococcus epidermidisparasitic diseasesOils VolatileMagydarisSicilyApiaceaeantimicrobial activitybiologyTraditional medicineOrganic ChemistrySettore CHIM/06 - Chimica Organicabiology.organism_classificationAntimicrobialαspringeneAnti-Bacterial AgentsPlant LeavesChemotaxonomyAlgerialipids (amino acids peptides and proteins)Composition (visual arts)DiterpenesAntibacterial activitySesquiterpenesApiaceae
researchProduct

Monotherapy with indacaterol once daily reduces the rate of exacerbations in patients with moderate-to-severe COPD: Post-hoc pooled analysis of 6 mon…

2014

Summary Background In patients with COPD, exacerbations are associated with poor quality of life and may shorten survival. Prevention of exacerbations is, therefore, a key objective in COPD management. Indacaterol, a once-daily ultra-long-acting β 2 -agonist, has been shown to reduce exacerbations in various studies. This pooled analysis evaluated the effect of indacaterol on exacerbations versus placebo. Methods Six-month data were pooled from three randomized, double-blind, and placebo-controlled studies: indacaterol 300 μg versus placebo (1 year); indacaterol 150 μg and 300 μg versus placebo (6 months); and indacaterol 150 μg versus placebo (6 months). All treatments were administered on…

β2-agonistPulmonary and Respiratory Medicinemedicine.medical_specialtyExacerbationKaplan-Meier EstimateQuinolonesPlaceboDrug Administration SchedulePooled analysisExacerbationsPulmonary Disease Chronic ObstructiveFEV1/FVC ratioDouble-Blind MethodForced Expiratory VolumeInternal medicineHumansCOPDMedicineAdrenergic beta-2 Receptor AgonistsRandomized Controlled Trials as TopicIndacaterolCOPDDose-Response Relationship Drugbusiness.industryMinimal clinically important differenceHazard ratiomedicine.diseaseConfidence intervalBronchodilator AgentsClinical Trials Phase III as TopicAnesthesiaIndansIndacaterolbusinessBronchodilatormedicine.drugRespiratory Medicine
researchProduct

Beam-induced and cosmic-ray backgrounds observed in the ATLAS detector during the LHC 2012 proton-proton running period

2016

This paper discusses various observations on beam-induced and cosmic-ray backgrounds in the ATLAS detector during the LHC 2012 proton-proton run. Building on published results based on 2011 data, the correlations between background and residual pressure of the beam vacuum are revisited. Ghost charge evolution over 2012 and its role for backgrounds are evaluated. New methods to monitor ghost charge with beam-gas rates are presented and observations of LHC abort gap population by ghost charge are discussed in detail. Fake jets from colliding bunches and from ghost charge are analysed with improved methods, showing that ghost charge in individual radio-frequency buckets of the LHC can be resol…

Большой адронный коллайдерbackground [beam]Physics::Instrumentation and DetectorsMonte Carlo methodPerformance of high energy physics detectorJet (particle physics)01 natural sciencesHigh Energy Physics - ExperimentSubatomär fysikHigh Energy Physics - Experiment (hep-ex)pressureSubatomic Physicsscattering [p p][PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Instrumentationпротон-протонные столкновенияQCMathematical PhysicsPhysicseducation.field_of_studyPerformance of high energy physics detectorsLarge Hadron ColliderSettore FIS/01 - Fisica SperimentaleBeam-intensity monitors; Beam-line instrumentation (beam position and profile monitors; Bunch length monitors); Data analysis; Performance of high energy physics detectors; Instrumentation; Mathematical PhysicsData analysiMonte Carlo [numerical calculations]ATLASbuildingsBunchesCERN LHC CollBeam-intensity monitorBeam-line instrumentation (beam position and profile monitorComputingMethodologies_DOCUMENTANDTEXTPROCESSINGcolliding beams [p p]Particle Physics - ExperimentParticle physicsCiências Naturais::Ciências Físicas530 PhysicsAstrophysics::High Energy Astrophysical PhenomenaPopulation:Ciências Físicas [Ciências Naturais]Beam-line instrumentation (beam position and profile monitorsData analysisFOS: Physical sciencesgapCosmic ray530Bunch length monitors)Nuclear physicsATLAS LHC High Energy Physics510 Mathematics0103 physical sciencesBeam-line instrumentation (beam position and profile monitors;; beam-intensity monitors; bunch length monitors); Data analysis;; Performance of High Energy Physics Detectors; LEPHigh Energy Physicsddc:610010306 general physicseducationMuonScience & Technologycosmic radiation [muon]010308 nuclear & particles physicsFísicaLEPBeam-intensity monitorsghostcorrelationExperimental High Energy PhysicsBeam-line instrumentation (beam position and profile monitors; beam-intensity monitors; bunch length monitors); Data analysis; Performance of High Energy Physics DetectorsBeam-line instrumentation (beam position and profile monitors; beam-intensity monitors; bunch length monitors)Physics::Accelerator PhysicsPerformance of High Energy Physics DetectorsATLAS детекторBeam (structure)experimental resultsbeam-line instrumentation
researchProduct

Верхнелатышский диалект

1989

Сборник содержит статьи по вопросам лексикологии, фонетики, фонологии и морфологии верхнелатышского диалекта.

Верхнелатышский диалектЛатгальская письменностьЛатышский языкLatgaliešu valodaLatviešu valodas dialektoloģijaДиалектологияЛатгальские говоры:HUMANITIES and RELIGION::Languages and linguistics::Other languages::Baltic languages [Research Subject Categories]
researchProduct

Краткая историческая справка развития и переустройства Рижского железнодорожного узла к открытию Александровского Путепровода в городе Риги

1905

Nosaukums uz vāka: Къ открытію Александровскаго путепровода въ гор. Ригѣ, 1904-1905.

Железнодорожные узлы - РигаRailway engineering:TECHNOLOGY::Civil engineering and architecture::Building engineering [Research Subject Categories]Dzelzceļa līnijas - projektēšana un celtniecība (Latvija Rīga)Железнодорожные путиDzelzceļi - projektēšana un celtniecība (Latvija Rīga)Latvijas dzelzceļš - vēsture
researchProduct

Контекстуально обусловленная вариативность единиц языка

1989

На материале германских, романских, а также латышского языков в сборнике рассматриваются контекстные условия варьирования языковых единиц всех уровней: фонетического, морфологического, синтаксического.

Латышский языкГрамматикаГерманские языкиValodniecībaФонетикаЯзыкознаниеСинтаксис:HUMANITIES and RELIGION::Languages and linguistics::Linguistic subjects [Research Subject Categories]Романские языки
researchProduct

Грамматика маньчжурскаго языка [Грамматика маньчжурского языка]

1873

Маньчжурский язык - ГрамматикаMandžūru valoda - GramatikaManchu language - Grammar:HUMANITIES and RELIGION::Languages and linguistics::Other languages::Altaic languages [Research Subject Categories]
researchProduct

Сборник всех правил и узаконений со всеми разъяснениями и дополнениями, о поступлении на службу вольноопределяющимися и охотниками в сухопутные войск…

1913

Министерство внутренних дел Российской империи - cборник циркуляров и инструкцийRecruitment of armed forces:HUMANITIES and RELIGION::History and philosophy subjects::History subjects::History [Research Subject Categories]Военная служба России - историяMilitārais dienests Krievijā - tiesību vēstureBruņoto spēku komplektēšana - Krievijas vēsture:SOCIAL SCIENCES::Other social sciences::Military intelligence and security service [Research Subject Categories]
researchProduct