Search results for "Ull"
showing 10 items of 3152 documents
Rilievo di un ephemeral gully nell’area sperimentale di Sparacia mediante una tecnica fotografica
2016
Nella memoria sono riportati i risultati dell’applicazione di una tecnica imagebased per il monitoraggio di un ephemeral gully formatosi nel gennaio 2015 nell’area sperimentale di Sparacia. Nel gully, lungo 54 m, sono state individuate 24 sezioni trasversali che sono state rilevate in campo mediante l’uso di un profilometro. L’indagine ha inoltre previsto la realizzazione di un modello tridimensionale del terreno (DTM) ottenuto con l’impiego di un numero elevato di fotografie della stessa scena acquisite da differenti punti di vista (Tecnica “Structure-From Motion” SFM e “Multi-View-Stereo MVS). Dal DTM tridimensionale (3D) e dal modello 2.5D sono stati estratti i profili delle sezioni tras…
Antitumor Effects of a Combined 5-Aza-2′Deoxycytidine and Valproic Acid Treatment on Rhabdomyosarcoma and Medulloblastoma in Ptch Mutant Mice
2009
Abstract Patched (Ptch) heterozygous mice develop medulloblastoma (MB) and rhabdomyosarcoma (RMS) resembling the corresponding human tumors. We have previously shown that epigenetic silencing of the intact Ptch allele contributes to tumor formation in this model. Here, we investigated whether targeting of epigenetic silencing mechanisms could be useful in the treatment of Ptch-associated cancers. A reduction of endogenous DNA methyltransferase1 (Dnmt1) activity significantly reduced tumor incidence in heterozygous Ptch knockout mice. A combined treatment with the Dnmt inhibitor 5-aza-2′deoxycytidine (5-aza-dC) and the histone deacetlyase (HDAC) inhibitor valproic acid (VPA) efficiently prev…
Fen1 is induced p53 dependently and involved in the recovery from UV-light-induced replication inhibition.
2005
Mouse embryonic fibroblasts (MEFs) that lack p53 are hypersensitive to the cytotoxic and genotoxic effect of ultraviolet (UV-C) light. They also display a defect in the recovery from UV-C-induced DNA replication inhibition. An enzyme involved in processing stalled DNA replication forks is flap endonuclease 1 (Fen1). Gene expression profiling of UV-C-irradiated MEFs revealed fen1 to be upregulated, which was confirmed by RT-PCR and Western blot experiments. Increased Fen1 levels upon UV-C exposure are due to transcriptional activation, as revealed by inhibitor studies. Fen1 induction was dose- and time-dependent; it occurred on protein level already 3 h after irradiation. Induction of Fen1 b…
Role of photoactive layer morphology in high fill factor all-polymer bulk heterojunction solar cells
2011
We report on the realization of all-polymer solar cells based on blends of poly(3-hexylthiophene-2,5-diyl) (P3HT) as a donor and poly{[N,N'-bis(2-octyldodecyl)-naphthalene-1,4,5,8-bis(dicarboximide)-2,6-diyl]-alt-5,5'-(2,2'-bithiophene)} (P(NDI2OD-T2)) as an acceptor. High fill factors are demonstrated for the first time in this class of devices suggesting high dissociation efficiency for the bounded electron-hole pairs and balanced electron and hole mobility along the thin films. The use of the high-mobility n-type P(NDI2OD-T2) polymer enables us to overcome one of the problems limiting the efficiency of all-polymer solar cells, resulting in fill factors comparable with those reported for …
Three-dimensional solvation structure of ethanol on carbonate minerals
2020
Calcite and magnesite are important mineral constituents of the earth’s crust. In aqueous environments, these carbonates typically expose their most stable cleavage plane, the (10.4) surface. It is known that these surfaces interact with a large variety of organic molecules, which can result in surface restructuring. This process is decisive for the formation of biominerals. With the development of 3D atomic force microscopy (AFM) it is now possible to image solid–liquid interfaces with unprecedented molecular resolution. However, the majority of 3D AFM studies have been focused on the arrangement of water at carbonate surfaces. Here, we present an analysis of the assembly of ethanol – an o…
FRIPON: a worldwide network to track incoming meteoroids
2020
Context. Until recently, camera networks designed for monitoring fireballs worldwide were not fully automated, implying that in case of a meteorite fall, the recovery campaign was rarely immediate. This was an important limiting factor as the most fragile - hence precious - meteorites must be recovered rapidly to avoid their alteration. Aims. The Fireball Recovery and InterPlanetary Observation Network (FRIPON) scientific project was designed to overcome this limitation. This network comprises a fully automated camera and radio network deployed over a significant fraction of western Europe and a small fraction of Canada. As of today, it consists of 150 cameras and 25 European radio receiver…
Valoda: nozīme un forma. 2. Gramatizēšanās un leksikalizēšanās latviešu valodas sistēmā
2012
Krājums „Valoda: nozīme un forma. 2. Gramatizēšanās un leksikalizēšanās latviešu valodas sistēmā” iecerēts kā 2010. un 2011. gada semināros „Gramatizēšanās un leksikalizēšanās latviešu valodas sistēmā” nolasīto referātu apkopojums.
Assessing the format and content of journal published and non-journal published rapid review reports: A comparative study
2020
Background As production of rapid reviews (RRs) increases in healthcare, knowing how to efficiently convey RR evidence to various end-users is important given they are often intended to directly inform decision-making. Little is known about how often RRs are produced in the published or unpublished domains, and what and how information is structured. Objectives To compare and contrast report format and content features of journal-published (JP) and non-journal published (NJP) RRs. Methods JP RRs were identified from key databases, and NJP RRs were identified from a grey literature search of 148 RR producing organizations and were sampled proportionate to cluster size by organization and pro…
Unraveling the literature chaos around free ammonia inhibition in anaerobic digestion
2020
International audience; This review aims at providing a unified methodology for free ammonia nitrogen (FAN) calculation in anaerobic digesters, also identifying the factors causing the huge disparity in FAN inhibitory limits. Results show that assuming ideal equilibria overestimates the FAN concentrations up to 37% when compared to MINTEQA2 Equilibrium Speciation Model, used as reference. The Davies equation led to major improvements. Measuring the concentrations of NH 4 þ , Na þ and K þ was enough to achieve major corrections. The best compromise between complexity and accuracy was achieved with a novel modified Davies equation, with systematic differences in FAN concentrations of 2% when …
La controvertida indemnización por lesión de los derechos fundamentales de las personas trabajadoras
2021
El reconocimiento y cuantificación de las indemnizaciones por vulneración de derechos fundamentales en el orden social de la jurisdicción ha sido, desde siempre, y por diferentes razones, una cuestión especialmente compleja. En ciertos casos ¿como sucede con la automaticidad del daño moral derivado de la violación del derecho fundamental- las contradicciones y vaivenes judiciales son ya un ¿clásico¿ en la materia; en otros, las dudas guardan relación con el significado y la repercusión que una incorporación legal efectuada por la LRJS -la finalidad preventiva de la indemnización- debe tener en la práctica judicial; y, finalmente, las discrepancias se refieren a la posibilidad misma de conce…