Search results for "Ultraviolet light"

showing 10 items of 51 documents

Effect of ultraviolet light, methyl methanesulfonate and ionizing radiation on the genotoxic response and apoptosis of mouse fibroblasts lacking c-Fo…

2001

c-Fos and p53 are DNA damage-inducible proteins that are involved in gene regulation, cell cycle checkpoint control and cell proliferation following exposure to genotoxic agents. To investigate comparatively the role of c-Fos and p53 in the maintenance of genomic stability and the induction of apoptosis, we generated mouse fibroblast cell lines from knockout mice deficient for either c-fos (fos -/-) or p53 (p53-/-) or for both gene products (fosp53-/-). The sensitivity of these established cell lines was compared with the corresponding wild-type cells as to the cytotoxic, clastogenic and apoptosis-inducing effects of ultraviolet (UV-C) light and methyl methanesulfonate (MMS). Additionally, …

Programmed cell deathTime FactorsCell cycle checkpointCell SurvivalUltraviolet RaysHealth Toxicology and MutagenesisBlotting WesternApoptosisBiologyToxicologyPolymerase Chain ReactionCell LineMiceNecrosischemistry.chemical_compoundRadiation IonizingGeneticsUltraviolet lightAnimalsCytotoxic T cellCells CulturedGenetics (clinical)Chromosome AberrationsMice KnockoutCell growthDose-Response Relationship RadiationFibroblastsBlotting NorthernMethyl MethanesulfonateMolecular biologyMethyl methanesulfonatechemistryApoptosisCell cultureTumor Suppressor Protein p53Proto-Oncogene Proteins c-fosDNA DamageMutagensMutagenesis
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Modulating the luminance of organic light-emitting diodes via optical stimulation of a photochromic molecular monolayer at transparent oxide electrode

2020

Nanoscale 12(9), 5444-5451 (2020). doi:10.1039/D0NR00724B

Solar cells of the next generationMaterials sciencediarylethenes organic light-emitting diode photochromism self-assembled monolayers02 engineering and technologyElectroluminescence010402 general chemistry01 natural scienceschemistry.chemical_compoundDiaryletheneOLEDUltraviolet lightGeneral Materials ScienceDiodeSettore CHIM/02 - Chimica Fisicabusiness.industry600021001 nanoscience & nanotechnology0104 chemical sciencesIndium tin oxidechemistryElectrodeOptoelectronicsCharge carrier0210 nano-technologybusinessddc:600Nanoscale
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Post-flare Ultraviolet Light Curves Explained with Thermal Instability of Loop Plasma

2012

In the present work, we study the C8 flare that occurred on 2000 September 26 at 19:49 UT and observed by the Solar and Heliospheric Observatory/Solar Ultraviolet Measurement of Emitted Radiation spectrometer from the beginning of the impulsive phase to well beyond the disappearance in the X-rays. The emission first decayed progressively through equilibrium states until the plasma reached 2-3 MK. Then, a series of cooler lines, i.e., Ca X, Ca VII, Ne VI, O IV, and Si III (formed in the temperature range log T = 4.3-6.3 under equilibrium conditions), are emitted at the same time and all evolve in a similar way. Here, we show that the simultaneous emission of lines with such a different forma…

Sun: flaresPhysicsSolar flareSun: coronaAstrophysics::High Energy Astrophysical PhenomenaAstronomy and AstrophysicsAstrophysicsPlasmaSun: UV radiationLight curvemedicine.disease_causelaw.inventionSettore FIS/05 - Astronomia E AstrofisicainstabilitiesSpace and Planetary SciencelawExtreme ultravioletPhysics::Space PhysicsUltraviolet lightmedicineAstrophysics::Solar and Stellar Astrophysicscorona ; Sun: flares ; Sun: UV radiation [instabilities ; Sun]UltravioletLine (formation)Flare
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Short-Term Stability of Lysergic Acid Diethylamide (LSD), N-Desmethyl-LSD, and 2-Oxo-3-hydroxy-LSD in Urine, Assessed by Liquid Chromatography–Tandem…

2002

Lysergic acid diethylamide (LSD) is one of the most potent hallucinogenic agents known. Recently, data on emergency department episodes related to the use of drugs commonly thought as “club drugs” have also included LSD (1). Confirmation of LSD use by testing biological fluids is still an analytical challenge because of its extensive, rapid metabolism and its instability (2)(3)(4). After ingestion of a typical street dose (40–120 μg), the concentration of LSD in urine falls to <1 μg/L within a few hours (2)(5)(6). Recently, N -desmethyl-LSD (nor-LSD) and 2-oxo-3-hydroxy-LSD (O-H-LSD) have been identified as LSD metabolites in human urine (7)(8). Measured nor-LSD concentrations were reported…

Time FactorsChromatographyChemistryBiochemistry (medical)Clinical BiochemistryMetabolismUrineMass spectrometryMass SpectrometryLysergic Acid DiethylamideDrug StabilityLiquid chromatography–mass spectrometryHallucinogensUltraviolet lightmedicineHumansIngestionQuantitative analysis (chemistry)Chromatography LiquidLysergic acid diethylamidemedicine.drugClinical Chemistry
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Light-induced resistance of the keratin network to the filament-disrupting tyrosine phosphatase inhibitor orthovanadate.

2003

Epidermal keratinocytes respond to low-dose light irradiation by inducing signaling cascades that lead to long-term effects on gene transcription thereby protecting cells against damage. In contrast, little is known about immediate light-induced alterations of structural proteins. We have made the intriguing observation that light produces fundamental changes in the properties of the keratin filament system of cultured epidermoid A-431 cells. A short light exposure (1–10 min) causes the keratin cytoskeleton to become immediately resistant to the tyrosine phosphatase inhibitor orthovanadate, which otherwise disrupts the keratin filament network completely in just a few minutes. This protecti…

Ultraviolet Raysultraviolet lightDrug ResistanceIntermediate FilamentsDermatologyProtein tyrosine phosphatasemacromolecular substancesBiologyBiochemistryProtein filamentKeratinUltraviolet lightTumor Cells CulturedHumansVanadatePhosphorylationIntermediate filamentMolecular Biologychemistry.chemical_classificationintermediate filamentKeratin Filamentintegumentary systemVulvar NeoplasmsvanadateCell BiologyMolecular biologyCell biologychemistryEpidermal CellsPhosphorylationKeratinsFemaleProtein Tyrosine PhosphatasesVanadatescytokeratinThe Journal of investigative dermatology
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Interfacial Modification for High-Efficiency Vapor-Phase-Deposited Perovskite Solar Cells Based on a Metal Oxide Buffer Layer.

2018

Vacuum deposition is one of the most technologically relevant techniques for the fabrication of perovskite solar cells. The most efficient vacuum-based devices rely on doped organic contacts, compromising the long-term stability of the system. Here, we introduce an inorganic electron-transporting material to obtain power conversion efficiencies matching the best performing vacuum-deposited devices, with open-circuit potential close to the thermodynamic limit. We analyze the leakage current reduction and the interfacial recombination improvement upon use of a thin (<10 nm) interlayer of C60, as well as a more favorable band alignment after a bias/ultraviolet light activation process. This wo…

Work (thermodynamics)FabricationMaterials sciencebusiness.industryDopingOxide02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences7. Clean energy0104 chemical scienceschemistry.chemical_compoundVacuum depositionchemistryUltraviolet lightOptoelectronicsGeneral Materials SciencePhysical and Theoretical Chemistry0210 nano-technologybusinessLayer (electronics)Perovskite (structure)The journal of physical chemistry letters
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Do Tengmalm's owls see vole scent marks visible in ultraviolet light?

1997

Scent markings (urine and faeces) of small mammals are visible in ultraviolet (UV) light. Diurnal kestrels, Falco tinnunculususe them as a cue to find areas of food abundance. We studied whether vole-eating, nocturnal Tengmalm's owls, Aegolius funereuscan see vole scent marks using UV-vision. In a laboratory experiment, 14 young (less than 6 months old) and 14 adult (more than 6 months old) owls were individually given a choice between four adjacent arenas: (1) an arena with vole urine and faeces in UV light; (2) an arena with vole urine and faeces in visible light; (3) a clean arena in UV light; and (4) a clean arena in visible light. Owls did not prefer any of the four arenas. Our results…

biologyAegoliusEcologyUltraviolet lightAnimal Science and ZoologyVoleNocturnalLaboratory experimentbiology.organism_classificationFalco tinnunculusEcology Evolution Behavior and SystematicsAnimal behaviour
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&lt;title&gt;Effect of light exposure on dislocation mobility in fullerite C60 crystals&lt;/title&gt;

2001

The illumination-time evolution and the wavelength dependence of the photoinduced changes in dislocation mobility on the (111) face of C60 single crystals in air for the wavelength range 150 - 900 nm and power densities 0.2 - 2 mW/cm2 has been investigated. The results show that the light exposure in air leads to the decrease of the dislocation mobility. The magnitude of the effect as a function of the illumination time was investigated and a two-stage relationship was obtained. The ultraviolet light was found to be more effective than the visible light in the photoinduced reduction of dislocation mobility and solubility. In the wavelength range of 150 - 700 nm, the reduction of dislocation…

chemistry.chemical_classificationMaterials sciencePhotonbusiness.industryPolymerPhoton energyMolecular physicsWavelengthPolymerizationchemistryUltraviolet lightOptoelectronicsDislocationbusinessVisible spectrumOptical Organic and Inorganic Materials
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Photoaffinity labeling of the coupling factor 1 from the thermophilic bacterum PS3 by 8-azido ATP

1984

AbstractTo localize the nucleotide binding sites of the F1ATPase (TF1) from the thermophilic bacterium PS3 we have used 14C-labeled 8-azido ATP (8-N3ATP) as photoaffmity label. 8-N3ATP is hydrolyzed by the F,ATPase in the absence of ultraviolet light. Irradiation by ultraviolet light of the enzyme in the presence of 8-N3ATP results in reduction of ATPase activity and in preferential nucleotide specific labeling of the α subunits (0.8–0.9 mol 8-N3ATP/TF1,α:β = 4:1). Inactivation and labeling do not depend on the presence of Mg2+. Both effects decrease upon addition of various nucleotide di- or triphosphates.

chemistry.chemical_classificationPhotoaffinity labelingStereochemistryNoncatalytic nucleotide binding siteThermophileBiophysicsCell BiologyBiochemistryCoupling (electronics)HydrolysisEnzymechemistryStructural BiologyPhotoaffinity labelingMoleBacterial F1ATPaseGeneticsUltraviolet lightCatalytic nucleotide binding siteNucleotideThermophilic bacterium PS3Molecular BiologyFEBS Letters
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The production of resveratrol (3,5,4'‐trihydroxystilbene) by grapevinein vitrocultures, and its application to screening for grey mould resistance

1992

The ability of grapevine in vitro cultures to synthesise the phytoalexin precursor resveratrol in response to ultraviolet light irradiations is investigated in order to develop methods for screening for resistance to grey mould (Botrytis cinerea Pers.) in grapevines produced as a result of somatic embryogenesis. It is demonstrated that resveratrol formation can be reproducibly induced in leaves of in vitro plantlets. Differences in the production of resveratrol among the three varieties of Vitis vinifera tested (Pinot Noir, Chardonnay and Cabernet Sauvignon) were consistent with observations regarding their field susceptibility to grey mould. The use of phytoalexin induction and of in vitro…

chemistry.chemical_classificationSomatic embryogenesisbiologyScreening testPhytoalexinfood and beveragesHorticultureResveratrolbiology.organism_classificationIn vitroHorticulturechemistry.chemical_compoundchemistryBotanyUltraviolet lightVitis viniferaFood ScienceBotrytis cinereaJournal of Wine Research
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