Search results for "Unity"
showing 10 items of 3852 documents
The echinoderm innate humoral immune response
2015
Abstract: Multicellular organisms have an immune system, which is essential for the survival of living beings. Interest in the immune system has been expanded since common characteristics of innate immunity between Drosophila melanogaster (Meigen, 1830) and mammals were discovered in the 1980. Since then, immunology has mainly focused on the adaptive immune system that seems to be restricted to vertebrates. Unlike the innate immunity, the adaptive one is acquired after exposure to a specific antigen (Ag) and includes: antigen-presenting cells such as macrophages, proliferation of B and T lymphocytes, Ag-specific antibody/cytokine production and immunological memory. Innate immunity is inste…
European expert opinion on the management of invasive candidiasis in adults
2011
Item does not contain fulltext This report discusses the present status of antifungal therapy and treatment options for candidaemia, considered by experts in the field in Europe. A conference of 26 experts from 13 European countries was held to discuss strategies for the treatment and prevention of invasive candidiasis, with the aim of providing a review on optimal management strategies. Published and unpublished comparative trials on antifungal therapy were analysed and discussed. Commonly asked questions about the management of candidaemia were selected, and possible responses to these questions were discussed. Panellists were then asked to respond to each question by using a touchpad ans…
<p>Isolation and Functions of Extracellular Vesicles Derived from Parasites: The Promise of a New Era in Immunotherapy, Vaccination, and Diagno…
2020
Experimental and epidemiological evidence shows that parasites, particularly helminths, play a central role in balancing the host immunity. It was demonstrated that parasites can modulate immune responses via their excretory/secretory (ES) and some specific proteins. Extracellular vesicles (EVs) are nano-scale particles that are released from eukaryotic and prokaryotic cells. EVs in parasitological studies have been mostly employed for immunotherapy of autoimmune diseases, vaccination, and diagnosis. EVs can carry virulence factors and play a central role in the development of parasites in host cells. These molecules can manipulate the immune responses through transcriptional changes. Moreo…
The role of embeddedness and top management teams on subsidiary initiative
2018
The importance of subsidiaries reaches its pick with their entrepreneurial role. Subsidiary initiatives (SI) are seen as “discrete, proactive undertaking that advances a new way for the corporation to use or expand its resources” (Birkinshaw, 2014, p. 203), which starts with the identification of an opportunity and should achieve the commitment of resources. Nonetheless, though initiatives are beneficial for the entire MNC (Bartlett & Ghoshal, 1988; Birkinshaw & Hood, 2000; Birkinshaw et al., 2005), they are not necessarily well receive by HQ but instead the MNC corporate immune system activates and initiative are rejected (Birkinshaw & Ridderstråle, 1999). This happens because initiatives …
DELL’UTRI E CONTRADA “GEMELLI DIVERSI”: È LA REVISIONE EUROPEA LO STRUMENTO DI OTTEMPERANZA ALLE SENTENZE CEDU
2017
La Cassazione nega l’origine giurisprudenziale del concorso esterno in associazione mafiosa e individua il rimedio della revisione europea per l’attuazione della decisione CEDU nei confronti di soggetti in posizioni simili a quella di Contrada. Il percorso offre l’occasione per riflettere sulla connotazione “oggettiva” della prevedibilità e sull’uguaglianza di trattamento dei condannati. Italian supreme Court denies that the origin of external participation in mafia-type criminal association lies in case law and envisages the European review as the tool to comply with ECtHR judgements in similar cases to that of Contrada. This jurisprudence provides a proper opportunity for an in-depth exam…
Who turns to entrepreneurship later in life? - Push and pull in Finnish rural and urban areas
2014
Age is an important factor in entrepreneurship. The paths into entrepreneurship at a later age may be varied. Self-employment in later life may be either a form of partial retirement or a career option. Older individuals may also be pushed into self-employment. The focus of this paper is on the career choices of older individuals and their background motivations in Finland. The purpose is to analyse the factors and motives in terms of the push and pull dichotomy that lead individuals to enter self-employment at older ages in different types of labour markets in Finland, viz., rural and urban areas. Although some studies have focused on transitions to self-employment among older workers, que…
Normalizing biproportional methods
2002
International audience; Biproportional methods are used to update matrices: the projection of a matrix Z to give it the column and row sums of another matrix is R Z S, where R and S are diagonal and secure the constraints of the problem (R and S have no signification at all because they are not identified). However, normalizing R or S generates important mathematical difficulties: it amounts to put constraints on Lagrange multipliers, non negativity (and so the existence of the solution) is not guaranteed at equilibrium or along the path to equilibrium.
Priming for JA-dependent defenses using hexanoic acid is an effective mechanism to protect Arabidopsis against B. cinerea
2011
Abstract Soil drench treatments with hexanoic acid can effectively protect Arabidopsis plants against Botrytis cinerea through a mechanism based on a stronger and faster accumulation of JA-dependent defenses. Plants impaired in ethylene, salicylic acid, abscisic acid or glutathion pathways showed intact protection by hexanoic acid upon B. cinerea infection. Accordingly, no significant changes in the SA marker gene PR-1 in either the SA or ABA hormone balance were observed in the infected and treated plants. In contrast, the JA signaling pathway showed dramatic changes after hexanoic acid treatment, mainly when the pathogen was present. The impaired JA mutants, jin1-2 and jar1 , were unable …
Zvaigžņotā Debess: 2017, Vasara (236)
2017
Contents: In MEMORIAM of ANDREJS ALKSNIS: Curriculum Vitae of Andrejs Alksnis (1928-2017) ; Condolences and Parting Words ; List of Publications by Professor Andrejs Alksnis ; “ZVAIGŽŅOTĀ DEBESS” FORTY YEARS AGO: J.Francmanis. Enigma of Saturn’s Rings Brightness (abridged) ; E.Mūkins. Crater on Mercury Named After Rainis (abridged) ; Ā.Alksne. The Starry Sky in the Summer of 1977 (abridged) ; DEVELOPMENTS in SCIENCE: K.Schwartz. Early Universe Through the Eyes of Telescopes ; DISCOVERIES: K.Schwartz. Dwarf Galaxy Henize 2-10 with a Massive Black Hole ; J.Kuzmanis. Hot Topic – FRB 121102 ; SPACE RESEARCH and EXPLORATION: J.Kalvāns. Are Earth's Oceans of Interstellar Origin? ; J.Jaunbergs. ‘D…
Stylistic analysis of headlines in science journalism: A case study ofNew Scientist
2016
This article explores science journalism in the context of the media competition for readers’ attention. It offers a qualitative stylistic perspective on how popular journalism colonizes science communication. It examines a sample of 400 headlines collected over the period of 15 months from the ranking of five ‘most-read’ articles on the website of the international magazine New Scientist. Dominant lexical properties of the sample are first identified through frequency and keyness survey and then analysed qualitatively from the perspective of the stylistic projection of newsworthiness. The analysis illustrates various degrees of stylistic ‘hybridity’ in online popularization of scientific r…