Search results for "Unity"

Breast cancer in previously thyroidectomized patients: which thyroid disorders are a risk factor?

2021

The aim of this study was to evaluate whether there are thyroid diseases in which breast cancer will appear later as well as the role of autoimmunity. This was a retrospective observational study. A total of 410 females (thyroid surgery and later breast cancer) and 524 females (thyroid surgery only) were compared with regard to pathological thyroid findings, thyroid hormones, thyroid autoimmunity and type of breast cancer. Thyroid autoimmunity, especially antithyroid peroxidase antibodies, significantly increased the risk of breast cancer (p < 0.01); however, this was not true for other thyroid diseases, including thyroid cancer. No variant of breast cancer was predominant, and only thyroid…

Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study

2012

Item does not contain fulltext INTRODUCTION: A recent genome-wide association study in European systemic sclerosis (SSc) patients identified three loci (PSORS1C1, TNIP1 and RHOB) as novel genetic risk factors for the disease. The aim of this study was to replicate the previously mentioned findings in a large multicentre independent SSc cohort of Caucasian ancestry. METHODS: 4389 SSc patients and 7611 healthy controls from different European countries and the USA were included in the study. Six single nucleotide polymorphisms (SNP): rs342070, rs13021401 (RHOB), rs2233287, rs4958881, rs3792783 (TNIP1) and rs3130573 (PSORS1C1) were analysed. Overall significance was calculated by pooled analys…

Network Overlap and Network Blurring in Online Social Networks

2016

Online communities and the online social networks embedded become a prominent medium for social interactions. The success of social media depends on users’ willingness to continue investing their time and efforts in the absence of economic rewards, making psychological attachment critical to online communities. While prior studies identify that members do develop psychological commitment to online communities, why and how the commitment arises remain underexplored. This study focuses on the relationship between network overlap, a common feature of online social networks, and affective commitment to an online community. Drawing on the commitment theory and social network boundary theory, w…

Creativity, Comparison and Sharing in the Co-Creation of the Communication Campaign

2022

In the fourth chapter the evolution of Oltre's online campaign will be transversally analysed, focusing on the path of awareness acquisition by the second-generation youth involved in the co-creation process of the campaign. Afterwards, we will be analysing in detail the backstage of the creation of content. Through the participatory method, we will be highlighting how the content creators of our campaign selected the themes and the perspective from which to deal with them. We will be underlying how the content creators dismantled the circulating representation and built a counter-narrative or an alternative narrative and converted the idea, through a process of creative co-construction, in…

Autoimmunity and glaucoma

2019

Opportunity costs and efficiency of investments in mega sport events

2009

Economic analyses of mega sport events usually focus on the positive effects and legacies while ignoring opportunity costs and the efficiency of using scarce resources. Event opponents argue that decisions to invest public resources should also consider alternative uses of the money. This paper aims to clarify some of the issues surrounding the opportunity costs of mega sport events. By using the measure ‘efficiency’ (output/input) of alternative investments it will become clear that the decision to stage a mega sport event cannot be taken in isolation and that there are many factors that need to be considered. The argument put forward is based on a stakeholder’s perspective and a spatial d…

Feasibility studies for water reuse projects: an economical approach

2006

Usually the methodologies used to analyse the feasibility of water reuse projects are focused on the internal costs. The aim of this paper is to show a methodology to assess the feasibility of a water reuse project taking into account not just the internal impact, but also the external impact (environmental and social, for example) and the opportunity cost derived from the project. Internal benefit is obtained from the difference between internal income and internal costs. Internal income is obtained by multiplying the selling price of reclaimed water and the volume obtained. Internal costs are made up of the sum of investment costs, operating costs, financial costs and taxes. While some of…

Opportunity Costs of Ensuring Sustainability in Urban Water Services

2011

This paper assesses technical performance in the water industry in the Southern European region of Andalusia, while accounting for sustainability in the management of water. This allows the opportunity cost of producing sustainability to be evaluated. Given the low cost of raw water in Spain in relation to the estimated opportunity cost of saving this natural resource, wasting water becomes a profitable strategy for utility managers from a private perspective. However, this managerial strategy has a huge social cost in an area of Europe where the sustainable management of water is a pressing need. The conclusion is that environmental policy aimed at discouraging this wasteful behaviour is u…

3D-grafiikan optimointi mobiilialustalle Unity-ympäristössä

2016

Mobiilimarkkinoilta löytyy hyvin laaja kirjo erilaisia mobiilipelejä. Mobiililaitteet ovat laajimmalle levinnyt tietokonemuoto. Viimevuosina mobiililaitteiden graafiset ominaisuudet ovat nousseet sellaiselle tasolle, että niillä voidaan renderöidä upeita 3Dympäristöjä reaaliajassa. Silti mobiililaitteet vaativat optimointia sulavaan peligrafiikan laskemiseen. Tämä pro gradu tutkielma paneutuu 3D-mobiiligrafiikan optimointiin keskittyen Unity-pelimoottoriin. Teoriaosuudessa käydään läpi 3D-grafiikan luomisen peruskäytänteitä siirtyen Unityn käyttämään OpenGL ES liukuhihnaan ja sen optimointimahdollisuuksiin. Käytännön osuudessa testataan kolmioiden, valaistuksen, sekä varjostimien vaikutusta…

Erosive effect of industrialized fruit juices exposure in enamel and dentine substrates: An in vitro study

2021

Background Erosive tooth wear has been a highly prevalent and emerging phenomenon related to eating habits of the population. Aim: This study sought to investigate industrialized fruit juices exposure in enamel and dentine substrates in terms of erosive effect. Material and methods Human enamel and dentine specimens were randomized into 8 groups (n=8): Grape juice - Ades®, Grape juice - Del Valle Kapo®, Grape juice - Aurora®, Orange juice - Del Valle Kapo®, Orange juice - Ades®, Strawberry juice - Mais Vita®, Strawberry juice - Ades®, Citrus fruit juice - Tampico®. Specimens were submitted to an in vitro erosive challenge and to a microhardness test to evaluate the percentage of surface mic…