Search results for "Urinary bladder neoplasm"

showing 10 items of 145 documents

DNA-Ploidy, Morphometric-Stereological and P-Glycoprotein Study of Superficial Bladder Carcinomas

1992

We carried out a DNA-ploidy, morphometric-stereologic and P-glycoprotein study on 40 newly diagnosed superficial bladder cancer patients (G1-G2), correlating the results with histological grade and clinical outcome. Variations in the number of patients who present recurrences, progression or remain tumor-free during the whole follow-up period (at least 5 years) were not significant when related to nuclear size, proliferative diploid index, presence of aneuploidy and expression of P-glycoprotein. It is striking how the majority of disease-free subjects showed a proliferative diploid index higher than 10%. Moreover, 3 of them presented an aneuploid cell population. In our study, only histolog…

MalePathologymedicine.medical_specialtyUrologyCellPopulationAneuploidyNewly diagnosedBiomarkers TumormedicineHumansIn patientATP Binding Cassette Transporter Subfamily B Member 1educationDna ploidyP-glycoproteineducation.field_of_studyMembrane GlycoproteinsPloidiesbiologybusiness.industryDNA Neoplasmmedicine.diseaseNeoplasm Proteinsmedicine.anatomical_structureUrinary Bladder Neoplasmsbiology.proteinFemalePloidybusinessFollow-Up StudiesEuropean Urology
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Urine cytology, tumour markers and bladder cancer

1998

MalePathologymedicine.medical_specialtyUrologyUrineAntigens NeoplasmBiomarkers TumorHumansMedicineAcidic Fibroblast Growth FactorGrowth SubstancesUrine cytologyCarcinoma Transitional CellBladder cancerUrinary bladdermedicine.diagnostic_testbusiness.industryMedical screeningmedicine.diseaseTumor associated antigenmedicine.anatomical_structureTransitional cell carcinomaUrinary Bladder NeoplasmsBlood Group AntigensFemaleHistopathologybusinessBJU International
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Urachal Signet-ring Cell Carcinoma, A Rare Variant of Vesical Adenocarcinoma: Incidence And Pathologicalcriteria

1978

Abstract Of 715 cases of vesical tumors reviewed 18 adenocarcinomas were selected for further study, 5 of which fulfilled all criteria of urachal origin. Herein is reported 1 rare case of such a carcinoma of the signet-ring cell type and the morphological criteria of this variant are discussed briefly. After undergoing radical cystectomy and ureterosigmoidostomy the patient has been free of recurrent tumor or metastasis for 6 years.

MalePathologymedicine.medical_specialtybusiness.industryUrologymedicine.medical_treatmentIncidence (epidemiology)Middle Agedmedicine.diseaseAdenocarcinoma MucinousUrachusMetastasisCystectomyUreterosigmoidostomymedicine.anatomical_structureUrinary Bladder NeoplasmsSignet ring cell carcinomamedicineCarcinomaHumansAdenocarcinomabusinessUrachusJournal of Urology
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Bladder tumor staging: comparison of contrast-enhanced and gray-scale ultrasound

2009

OBJECTIVE. The purpose of this study was to evaluate the effectiveness of contrast-enhanced sonography in comparison with conventional sonography in differentiating muscle- infiltrating and superficial neoplasms of the urinary bladder. SUBJECTS AND METHODS. Conventional and contrast-enhanced sonography were performed on 34 consecutively registered patients with bladder tumors. All examinations were reviewed by two independent sonologists. At gray-scale sonography, interruption of the hyperechoic bladder wall was considered the main diagnostic criterion for differentiating superficial and infiltrating tumors. At contrast-enhanced sonography, a tumor was considered superficial when the hypoen…

MalePathologymedicine.medical_specialtytumorUrinary systemcontrast agent; staging; tumor; ultrasonography; ultrasound; urinary bladderContrast MediaDiagnosis DifferentialImage Interpretation Computer-AssistedBladder tumorMedicineHumansRadiology Nuclear Medicine and imagingNeoplasm InvasivenessAgedNeoplasm StagingUrinary bladdermedicine.diagnostic_testbusiness.industryultrasoundUltrasoundGeneral MedicineCystoscopyCystoscopystagingultrasonographyMiddle Agedcontrast agentmedicine.diseaseBladder tumor stagingGray scale ultrasoundmedicine.anatomical_structureROC CurveUrinary Bladder NeoplasmsFemaleRadiologyDifferential diagnosisbusinessInfiltration (medical)urinary bladder
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Bladder cancer index: cross-cultural adaptation into Spanish and psychometric evaluation.

2014

Background: The Bladder Cancer Index (BCI) is so far the only instrument applicable across all bladder cancer patients, independent of tumor infiltration or treatment applied. We developed a Spanish version of the BCI, and assessed its acceptability and metric properties. Methods: For the adaptation into Spanish we used the forward and back-translation method, expert panels, and cognitive debriefing patient interviews. For the assessment of metric properties we used data from 197 bladder cancer patients from a multi-center prospective study. The Spanish BCI and the SF-36 Health Survey were self-administered before and 12 months after treatment. Reliability was estimated by Cronbach’s alpha.…

MalePsychometricsAparell urinariSurveys and QuestionnairesProspective cohort studyCàncermedia_commonLanguageCognitionGeneral MedicinePatient outcomeControl de qualitatNeoplasias de la Vejiga UrinariaEstudios de ValidaciónPsicometríaBufeta -- CàncerFemalePsicometriaClinical psychologyCross-Cultural ComparisonQuality of lifemedicine.medical_specialtyPsychometricsUrinary bladder neoplasms:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Psychometrics [Medical Subject Headings]:Publication Characteristics::Study Characteristics::Validation Studies [Medical Subject Headings]Cronbach's alpha:Disciplines and Occupations::Social Sciences::Quality of Life [Medical Subject Headings]medicine:Diseases::Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Urologic Neoplasms::Urinary Bladder Neoplasms [Medical Subject Headings]media_common.cataloged_instanceHumansEuropean UnionEuropean unionAgedNeoplasm StagingGynecologyAnalysis of VarianceBladder cancerbusiness.industryResearchPublic Health Environmental and Occupational HealthConstruct validityTranslatingmedicine.diseaseCross-cultural studiesUnited StatesValidation studiesPatient outcomesCalidad de VidabusinessHealth and quality of life outcomes
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ICUD-EAU International Consultation on Bladder Cancer 2012: Urinary diversion.

2012

Context: A summary of the 2nd International Consultation on Bladder Cancer recommendations on the reconstructive options after radical cystectomy (RC), their outcomes, and their complications. Objective: To review the literature regarding indications, surgical details, postoperative care, complications, functional outcomes, as well as quality-of-life measures of patients with different forms of urinary diversion (UD). Evidence acquisition: An English-language literature review of data published between 1970 and 2012 on patients with UD following RC for bladder cancer was undertaken. No randomized controlled studies comparing conduit diversion with neobladder or continent cutaneous diversion…

MaleReoperationmedicine.medical_specialtyUrologymedicine.medical_treatmentUrinary BladderRenal functionContext (language use)Controlled studiesUrinary DiversionCystectomyCystectomyUreterosigmoidostomyMedicineHumansBladder cancerbusiness.industryUrinary retentionUrinary diversionUrinary Reservoirs ContinentRecovery of Functionmedicine.diseaseSurgeryTreatment OutcomeUrinary IncontinenceUrinary Bladder NeoplasmsQuality of LifeFemalemedicine.symptombusinessEuropean urology
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Spatial Interaction between Neighbouring Counties: Cancer Mortality Data in Valencia (Spain)

1995

The statistical analysis of geographical mortality data has usually been approached via regression models that include appropriate covariates. These models assume stochastic independence of mortality counts for neighbouring sites, a questionable assumption that spatial automodels (Besag, 1974, Journal of the Royal Statistical Society, Series B 36, 192-236) make unnecessary. This paper presents the use of the autopoisson distribution in order to detect spatial interaction between neighbouring sites. If this interaction results in being nonsignificant, the auto-Poisson distribution reduces to a usual Poisson regression model, a particular case of generalized linear models (McCullagh and Nelde…

MaleStatistics and ProbabilityGeneralized linear modelGLIMPoisson distributionGeneral Biochemistry Genetics and Molecular Biologysymbols.namesakeStomach NeoplasmsNeoplasmsStatisticsCovariateHumansPoisson DistributionPoisson regressionFertilizersDemographyCancer mortalityModels StatisticalNitratesGeneral Immunology and MicrobiologyApplied MathematicsSpatial interactionProstatic NeoplasmsRegression analysisGeneral MedicineGeographyUrinary Bladder NeoplasmsSpainColonic NeoplasmssymbolsRegression AnalysisGeneral Agricultural and Biological SciencesDemographyBiometrics
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High-Grade T1 on Re-Transurethral Resection after Initial High-Grade T1 Confers Worse Oncological Outcomes: Results of a Multi-Institutional Study

2018

The aim of this multicenter study was to investigate the prognostic impact of residual T1 high-grade (HG)/G3 tumors at re-transurethral resection (TUR of bladder tumor) in a large multi-institutional cohort of patients with primary T1 HG/G3 bladder cancer (BC).

MaleTime Factorsmedicine.medical_treatment:Medicina Básica [Ciências Médicas]Treatment outcomeBladder cancer; High risk; High-grade; Second look resection; Transurethral resection of bladder tumor; Aged; Aged 80 and over; Carcinoma Transitional Cell; Cystectomy; Disease Progression; Disease-Free Survival; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence Local; Prognosis; Progression-Free Survival; Recurrence; Regression Analysis; Time Factors; Treatment Outcome; Urinary Bladder Neoplasms; Urologic Surgical Procedures030232 urology & nephrologySettore MED/24 - Urologia0302 clinical medicineRecurrenceHigh-grade80 and overAged 80 and overTransurethral resection of bladder tumorCARCINOMA TRANSITIONAL CELLHigh riskBladder cancerFollow up studiesMiddle AgedPrognosisProgression-Free Survival3. Good healthScholarshipTreatment OutcomeLocal030220 oncology & carcinogenesisCiências Médicas::Medicina BásicaUrinary Bladder NeoplasmDisease ProgressionRegression AnalysisUrologic Surgical ProceduresFemaleSecond look resectionHumanmedicine.medical_specialtyTime FactorPrognosiUrologyBladder cancer; High risk; High-grade; Second look resection; Transurethral resection of bladder tumorCystectomyRegression AnalysiDisease-Free SurvivalResectionFollow-Up StudieCystectomy03 medical and health sciencesbladder cancer; high risk; high-grade; second look resection; transurethral resection of bladder tumor; aged; aged 80 and over; carcinoma transitional cell; cystectomy; disease progression; disease-free survival; female; follow-up studies; humans; malemedicineHumansProgression-free survivalAgedCarcinoma Transitional CellScience & Technologybusiness.industryGeneral surgeryDisease progressionCarcinomaNeoplasm RecurrenceUrinary Bladder NeoplasmsUrologic Surgical ProcedureTransitional CellTransurethral resection of bladder tumor.Neoplasm Recurrence LocalbusinessFollow-Up Studies
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Concordance and Clinical Significance of Uncommon Variants of Bladder Urothelial Carcinoma in Transurethral Resection and Radical Cystectomy Specimens

2014

To evaluate the concordance and prognostic role of histologic variants of bladder urothelial carcinoma in transurethral resection of bladder tumor (TURBT) and radical cystectomy (RC) specimens. METHODS Clinicopathologic information available at the time of RC and follow-up data from 4110 RC specimens, collected between January 2000 and December 2009 at 17 tertiary referral centers were retrospectively analyzed and evaluated for the presence or absence of uncommon variants of bladder urothelial carcinoma. The presence or absence of uncommon variants of bladder urothelial carcinoma was evaluated on previous TURBT specimens of patients undergoing RC. Cox regression was used to assess the impac…

MaleURINARY-BLADDER; CANCER; UPDATE; IMPACT; DIFFERENTIATIONIMPACTmedicine.medical_treatmentKaplan-Meier EstimateSettore MED/24 - UrologiaRetrospective StudieBladder cancer histologic variantsbladder urothelial carcinomaUrinary bladderMedicine (all)Middle AgedPrognosisCANCERDIFFERENTIATIONmedicine.anatomical_structureTreatment OutcomeUrinary Bladder Neoplasmbladder cancerFemaleHumanmedicine.medical_specialtyPrognosiConcordanceUrologyUrinary BladderUrologyCystectomyDisease-Free SurvivalFollow-Up StudieCystectomymedicineCarcinomaHumansClinical significanceAged; Carcinoma; Cystectomy; Disease-Free Survival; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Prognosis; Proportional Hazards Models; Retrospective Studies; Treatment Outcome; Urinary Bladder; Urinary Bladder Neoplasms; Urology; Medicine (all)Proportional Hazards ModelsRetrospective StudiesAgedBladder cancerProportional hazards modelbusiness.industryCarcinomaAged; Carcinoma; Cystectomy; Disease-Free Survival; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Prognosis; Proportional Hazards Models; Retrospective Studies; Treatment Outcome; Urinary Bladder; Urinary Bladder NeoplasmsCancermedicine.diseaseUrinary Bladder NeoplasmsProportional Hazards ModelUPDATEURINARY-BLADDERbusinessFollow-Up Studies
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Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted

2006

Abstract Tumours ferment glucose to lactate even in the presence of oxygen (aerobic glycolysis; Warburg effect). The pentose phosphate pathway (PPP) allows glucose conversion to ribose for nucleic acid synthesis and glucose degradation to lactate. The nonoxidative part of the PPP is controlled by transketolase enzyme reactions. We have detected upregulation of a mutated transketolase transcript (TKTL1) in human malignancies, whereas transketolase (TKT) and transketolase-like-2 (TKTL2) transcripts were not upregulated. Strong TKTL1 protein expression was correlated to invasive colon and urothelial tumours and to poor patients outcome. TKTL1 encodes a transketolase with unusual enzymatic prop…

Maleaerobic glycolysiCancer ResearchAdenocarcinomanPentose phosphate pathwayTransketolaseBiologyMetastasispentose phosphate pathway (PPP)Downregulation and upregulationPredictive Value of TestsmedicineHumansNeoplasm InvasivenessGlycolysisNeoplasm MetastasisMolecular Diagnosticsaerobic glycolysisAgedtransketolase-like-1 (TKTL1)transketolase (TKT)Gene Expression ProfilingCancerMiddle AgedPrognosismedicine.diseaseSurvival AnalysisWarburg effectUp-RegulationUrinary Bladder NeoplasmsOncologyBiochemistryAnaerobic glycolysispharmacodiagnostic markerColonic NeoplasmsCancer researchFemaleWarburg effectTransketolaseGlycolysisBritish Journal of Cancer
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