Search results for "Urologia"

LOWER RESPONSE TO INTRAVESICAL ADJUVANT THERAPY IN HIGH-RISK BLADDER CANCER COULD BE RELATED TO THE UROTHELIAL EXPRESSION OF EGFR

2017

EIACULAZIONE PRECOCE: EFFICACIA DEI TRATTAMENTI A CONFRONTO. TERAPIA MEDICA VS TERAPIA MEDICA IN ASSOCIAZIONE A PSICOTERAPIA GRUPPOANALITICA VS PSICO…

Lesion load may predict long-term cognitive dysfunction in multiple sclerosis patients

2015

Background: Magnetic Resonance Imaging (MRI) techniques provided evidences into the understanding of cognitive impairment (CIm) in Multiple Sclerosis (MS). Objectives: To investigate the role of white matter (WM) and gray matter (GM) in predicting long-term CIm in a cohort of MS patients. Methods: 303 out of 597 patients participating in a previous multicenter clinical-MRI study were enrolled (49.4% were lost at follow-up). The following MRI parameters, expressed as fraction (f) of intracranial volume, were evaluated: cerebrospinal fluid (CSF-f), WM-f, GM-f and abnormal WM (AWM-f), a measure of lesion load. Nine years later, cognitive status was assessed in 241 patients using the Symbol Dig…

"LUTS E DE NELLA PRATICA CLINICA ANDROLOGICA IN SICILIA: ANALISI EPIDEMIOLOGICA SU CONDIZIONI DI FAMILIARITA' (PATOLOGIE URO-GENITALI), COMORBIDITA',…

2009

Studio di validazione dell'ACE-R in lingua italiana nella popolazione degli young-old e degli old-old

2012

Introduction. The main aims of the study were the translation into Italian, and validation subsequently of the Addenbrooke's Cognitive Examination Revised (ACE-R), and the evaluation of its usefulness in discriminating cognitively normal subjects from patients with mild dementia. Methods. The ACE-R was translated and adapted into Italian. The Italian ACE-R was administrated to a group of 179 elderly subjects (72 cognitively intact and 107 subjects with mild dementia, mean age 75.4 years ± 6.4). The group was stratified in two sub-samples according to age, i.e. young-old (< 75 years) and old-old (≥ 75 years), in order to evaluate test's sensitivity and specificity in detecting dementia among…

EMpathy ability and emotion recognition in temporal lobe epilepsy and idhiopathic generalizede epileps

2013

Pre- and postsynaptic type-1 cannabinoid receptors control the alterations of glutamate transmission in experimental autoimmune encephalomyelitis

2013

Type-1 cannabinoid receptors (CB1R) are important regulators of the neurodegenerative damage in multiple sclerosis (MS) and in experimental autoimmune encephalomyelitis (EAE). In GABAergic striatal neurons, CB1R stimulation exerts protective effects by limiting inflammation-induced potentiation of glutamate-mediated spontaneous excitatory postsynaptic currents (sEPSCs). Here we show that CB1R located on GABAergic or on glutamatergic neurons are differentially involved in the pre- and postsynaptic alterations of sEPSCs caused by EAE in the striatum. After induction of EAE, mice selectively lacking CB1R on GABAergic neurons (GABA-CB1R-KO) showed exacerbated alterations of sEPSC duration in GA…

Disfunzioni sessuali, farmaci antiepilettici e profilo ormonale sierico negli uomini affetti da epilessia

2012

Razionale ed obiettivi: Le disfunzioni sessuali sono un problema relativamente comune nei pazienti di sesso maschile affetti da epilessia, la cui.prevalenza varia dal 38-71%. La loro eziologia non è conosciuta e potrebbe essere multifattoriale; possono essere implicati nella loro genesi sia l’epilessia che l’utilizzo di farmaci antiepilettici (FAE). L’assunzione di farmaci per la terapia dell’epilessia può essere all’origine della presenza di DS e di alterazioni ormonali e riproduttive in questa popolazione di pazienti. Lo scopo dello studio è valutare l’incidenza delle DS negli uomini con epilessia, valutando il tipo di epilessia, la frequenza delle crisi, il tipo di FAE utilizzato, il pro…

Disfunzioni sessuali, farmaci antiepilettici e profilo ormonale sierico negli uomini affetti da epilessia. Sexual disfunctions, antiepileptic drugs, …

2012

Sexual dysfunctions (SD) are a relatively common problem in men with epilepsy; the prevalence ranges from 38-71%. Etiology may be multifactorial and may involve both the epilepsy and the use of antiepileptic drugs. The purpose of this study was to evaluate the incidence of SD in epileptic men, assessing the type of epilepsy, seizures frequency, antiepileptic drugs used, the serum hormonal profile and the presence of psychiatric disorders.

Modulation of adrenergic responses of human vas deferens by K+ channel inhibitors

2010

The results suggest that charybdotoxin-sensitive, but iberiotoxin-insensitive, K+ channels are activated by stimulation with norepinephrine and electrical field stimulation to counteract the adrenergic-induced contractions of human vas deferens. Thus, inhibition of these channels increases significantly the contraction, an effect that appears to be mediated by an increase in Ca2+ entry through L-type voltage-dependent Ca2+ channels.