Search results for "User"

SymbioGenomesDB: a database for the integration and access to knowledge on host-symbiont relationships.

2014

Symbiotic relationships occur naturally throughout the tree of life, either in a commensal, mutualistic or pathogenic manner. The genomes of multiple organisms involved in symbiosis are rapidly being sequenced and becoming available, especially those from the microbial world. Currently, there are numerous databases that offer information on specific organisms or models, but none offer a global understanding on relationships between organisms, their interactions and capabilities within their niche, as well as their role as part of a system, in this case, their role in symbiosis. We have developed the SymbioGenomesDB as a community database resource for laboratories which intend to investigat…

BANΔIT: B’‐factor Analysis for Drug Design and Structural Biology

2020

The analysis of B‐factor profiles from X‐ray protein structures can be utilized for structure‐based drug design since protein mobility changes have been associated with the quality of protein‐ligand interactions. With the BANΔIT (B’‐factor analysis and ΔB’ interpretation toolkit), we have developed a JavaScript‐based browser application that provides a graphical user interface for the normalization and analysis of B’‐factor profiles. To emphasize the usability for rational drug design applications, we have analyzed a selection of crystallographic protein‐ligand complexes and have given exemplary conclusions for further drug optimization including the development of a B’‐factor‐supported pha…

GYROCOMPU: Toolbox Designed for the Analysis of Gyrotron Resonators

2020

The key point of gyrotron design is the analysis of the radio frequency (RF) behavior in gyrotron resonators. This article proposes a comprehensive, user-friendly and effective gyrotron design toolbox (GYROCOMPU) based on the MATLAB platform. GYROCOMPU associates a relatively complete set of codes for gyrotron analysis and integrates them together into a graphical user interface (GUI). The solving algorithm of the cold cavity equations and self-consistent equations is improved. The solving method improvement in these calculation algorithms renders the analysis more efficient and accurate. Three typical examples of gyrotrons working in the 140-GHz TE03 mode, 42-GHz TE03 mode, and 140-GHz TE1…

Total Correlation Spectroscopy (TOCSY) of Proteins Using Coaddition of Spectra Recorded with Several Mixing Times

1993

Technology in mental health

2008

Mental illness has been identified as one of the greatest challenges facing society in the coming decades. However, there are significant barriers to access for many people suffering from mental illness, including overburdened public health care systems, geographic distance from point of care, difficulties encountered by individuals in engaging with services, and the stigma associated with mental illness. Technology has the potential to significantly improve access, engagement, effectiveness and affordability of treatment, yet relatively little use has been made of technology to date. Significant opportunities exist for further research and development, but the domain throws up a variety of…

A Balancing Act-How Mental Health Professionals Experience Being Personal in Their Relationships with Service Users.

2017

Although being personal in relationships with service users is commonly described as an important aspect of the way that professionals help people with severe mental problems, this has also been described to bring with it a need to keep a distance and set boundaries.This study aims to explore how professionals working in psychiatric care view being personal in their relationships with users.Qualitative interviews with 21 professionals working in three outpatient psychiatric units, analyzed through thematic analysis.Being personal in their relationships with users was described as something that participants regarded to be helpful, but that also entails risks. Participants described how they…

Endocrine and Clinical Evaluation of 107 Patients With Advanced Prostatic Carcinoma Under Long-Term Pernasal Buserelin or Intramuscular Decapeptyl De…

1988

Three major assumptions emerged from these clinical and endocrine long-term studies. First, buserelin, given pernasally in the conventional doses, and Decapeptyl microcapsules administered intramuscularly in 5-week intervals are equally effective in terms of their long-term castration effect in previously untreated patients with prostatic carcinoma. However, Decapeptyl causes complete LH and subsequent testosterone down-regulation 1 week earlier than buserelin. Furthermore, this treatment is more convenient, and the compliance is better. Both LHRH analogues are equally well tolerated. Second, in groups of prostate cancer patients with far advanced disease treated with palliative intention, …

Navigating high-choice European political information environments : a comparative analysis of news user profiles and political knowledge

2021

The transition from low- to high-choice media environments has had far-reaching implications for citizens’ media use and its relationship with political knowledge. However, there is still a lack of comparative research on how citizens combine the usage of different media and how that is related to political knowledge. To fill this void, we use a unique cross-national survey about the online and offline media use habits of more than 28,000 individuals in 17 European countries. Our aim is to (i) profile different types of news consumers and (ii) understand how each user profile is linked to political knowledge acquisition. Our results show that five user profiles – news minimalists, social m…

Using protection motivation theory in the design of nudges to improve online security behavior

2019

Abstract We conducted an online experiment (n = 2024) on a representative sample of internet users in Germany, Sweden, Poland, Spain and the UK to explore the effect of notifications on security behaviour. Inspired by protection motivation theory (PMT), a coping message advised participants on how to minimize their exposure to risk and a threat appeal highlighted the potential negative consequences of not doing so. Both increased secure behavior – but the coping message significantly more so. The coping message was also as effective as both messages combined, but not so the threat appeal. Risk attitudes, age and country had a significant effect on behavior. Initiatives seeking to promote se…

An algorithm for simulating end-user behaviour in a real time pricing market

2015

The energy market has changed radically over the last decade, mainly due to an increased penetration of renewable energies. Now the end users have directly access to the energy market and can actively take part to the electricity market. Electricity customers can indeed modify their behavior through Demand Response, namely by means of pricing strategies that support a change in the end-users habits. This can be accomplished through a 'loads aggregator', a third party that collects the requests and signals for Active Demand-based services coming from the markets and the different actors of energy market. This paper describes a simulation framework to generate the simulated optimal behavior o…