Search results for "Uses"
showing 10 items of 1614 documents
Noziedzības cēloņi un to novēršana
2017
Bakalaura darba “Noziedzības cēloņi un to novēršana” mērķis ir sociālas problēmas iespējamo patieso cēloņu noskaidrošana, piedāvājot saprātīgus risinājumus to novēršanai. Kriminoloģiskā domāšana pieļauj starpdisciplināru izpēti, kas nav ierobežota ar juridiskiem terminiem vien. Lai arī tas uzdevumu padara grūtāku, mēģinājums tiks veikts. Par būtiskāko problēmjautājumu autors uzskata noziedzīga nodarījuma izdarītāja “brīvo gribu”, jo tā aizvien ir krimināltiesību pamatā, tomēr var izrādīties tikai ilūzija. Tiks aplūkoti divi galvenie ietekmējošo faktoru kopumi. Autors saglabā pārliecību, ka gudra šo faktoru ņemšana vērā var noziedzības novēršanu padarīt daudz efektīvāku.
Development of functionalized SYBR green II related cyanine dyes for viral RNA detection
2020
Fluorescent probes for sensing nucleic acids have found widespread use in the field of cell and molecular biology. However, probes combined with potential for post-synthetic conjugation, e.g. for intra-endosomal measurements of RNA, are unavailable. Herein we developed cyanine dyes that can be conjugated to viral capsid or other targets. First, we solved the crystal structure of SYBR Green II. The structural elucidation of this commonly used RNA probe provided the basis for synthesizing similar molecules with much desired function for post-synthetic conjugation. To address this need, cyanine dyes were prepared using an alternative synthesis protocol. All studied compounds showed considerabl…
Semantic Complexity in Natural Language
2015
This chapter presents the technical framework that the authors used to define fragments of natural languages and formulate questions as to their semantic complexity. It examines the study of the classical syllogistic and its extensions. It analyzes the semantic complexity of various salient fragments of English. It highlights that the language of argument, featuring transitive verbs, is in an objective sense inferentially no more complex than the language of classical syllogisms exemplified by argument, indeed, the analogous extension featuring ditransitive verbs involves only a modest increase in complexity. On the other hand, the language of argument, which adds relative clauses to the cl…
OPTEER, un dispositif de connaissance et d’analyse territoriale par et pour les acteurs de la transition énergétique
2018
International audience; The aim of this article is to illustrate, through the implementation and exploitation of the OPTEER platform (Territorial Energy Observation and Prospective at the Regional scale), how the various tools made available to territorial actors and what collective uses of geographic information have developed. Based on his experience of more than 10 years, around which crystallized operational developments and research experiments, are also evoked the new needs related to the requirements of the implementation of energy transition and the tracks of research,development and porting envisaged to guarantee the durability of the device.; Cet article a pour objectif d’illustre…
Ķīmisko elementu izmaiņas pēc apmežošanās ar parasto egli (PICEA ABIES(L.)KARST) bijušajās lauksaimniecības zemēs
2017
Pamestas un aizaugošas lauksaimniecības zemes ir mūsdienu Latvijas ainavas būtiska sastāvdaļa. Latvijā šī tendence parādījās pēc 1989.gada, kad notika pāreja no centralizētas jeb plānveida ekonomikas uz tirgus. Sociālekonomiskās un politiskās pārmaiņas negatīvi ietekmēja lauksaimniecību, padarot to par ekonomiski neizdevīgu nozari, tāpēc cilvēki pameta lauku teritorijas, lai pārceltos uz dzīvi pilsētās. Bakalaura darba ietvaros ir veikts pētījums par augsnes ķīmisko īpašību izmaiņām, kuras notikušas saistībā ar lauksaimniecībā izmantojamo zemju apmežošanos teritorijās, kur augsnes cilmiezi veido glacigēnie morēnas nogulumi. Apmežošanās procesa ietekme uz augsnes īpašībām ir aktuāla tēma Lat…
Experimental evolution of an RNA virus in cells with innate immunity defects
2015
Experimental evolution studies have shown that RNA viruses respond rapidly to directional selection and thus can adapt efficiently to changes in host cell tropism, antiviral drugs, or other imposed selective pressures. However, the evolution of RNA viruses under relaxed selection has been less extensively explored. Here, we evolved vesicular stomatitis virus in mouse embryonic fibroblasts knocked-out for PKR, a protein with a central role in antiviral innate immunity. Vesicular stomatitis virus adapted to PKR-negative mouse embryonic fibroblasts in a gene-specific manner, since the evolved viruses exhibited little or no fitness improvement in PKR-positive cells. Full-length sequencing revea…
Evidence for Positive Selection in the Capsid Protein-Coding Region of the Foot-and-Mouth Disease Virus (FMDV) Subjected to Experimental Passage Regi…
2001
We present sequence data from two genomic regions of foot-and-mouth disease virus (FMDV) subjected to several experimental passage regimens. Maximum-likelihood estimates of the nonsynonymous-to-synonymous rate ratio parameter (dN/dS) suggested the action of positive selection on some antigenic sites of the FMDV capsid during some experimental passages. These antigenic sites showed an accumulation of convergent amino acid replacements during massive serial cytolytic passages and also in persistent infections of FMDV in cell culture. This accumulation was most significant at the antigenic site A (the G-H loop of capsid VP1), which includes an Arg-Gly-Asp (RGD) cellular recognition motif. Our …
Parisuhde pikkulapsiperheessä
2011
Party autonomy regarding jurisdiction under the property regimes regulations
2021
The main accomplishment of the Property Regimes Regulations lies in their bringing more coherence into the cross-border family law adjudication. In the field of international jurisdiction, they strive to align the competence in couples? patrimony disputes to that in succession and in separation proceedings, or else to align the competence of the courts to the applicable law. These tendencies are clearly visible in the Regulations? provisions on choice of court agreements. Namely, the Regulations allow for such agreements, but severely limit parties? choice and the possible effects of these clauses. When succession or separation proceedings are pending, it is often only possible to institute…