Search results for "VARIATION"

showing 10 items of 2124 documents

A smart and operator independent system to delineate tumours in Positron Emission Tomography scans

2018

Abstract Positron Emission Tomography (PET) imaging has an enormous potential to improve radiation therapy treatment planning offering complementary functional information with respect to other anatomical imaging approaches. The aim of this study is to develop an operator independent, reliable, and clinically feasible system for biological tumour volume delineation from PET images. Under this design hypothesis, we combine several known approaches in an original way to deploy a system with a high level of automation. The proposed system automatically identifies the optimal region of interest around the tumour and performs a slice-by-slice marching local active contour segmentation. It automa…

Lung NeoplasmsComputer sciencemedicine.medical_treatmentPET imagingPattern Recognition Automated030218 nuclear medicine & medical imaging0302 clinical medicineNeoplasmsImage Processing Computer-AssistedSegmentationDiagnosis Computer-AssistedNeoplasm MetastasisRadiation treatment planningSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniObserver VariationActive contour modelmedicine.diagnostic_testBrain NeoplasmsPhantoms ImagingComputer Science ApplicationsHead and Neck NeoplasmsPositron emission tomography030220 oncology & carcinogenesis18F-fluoro-2-deoxy-d-glucoseAlgorithms18F-fluoro-2-deoxy-d-glucose and 11C-labeled methionine PET imagingSimilarity (geometry)Health InformaticsSensitivity and SpecificityNOActive contour algorithm03 medical and health sciencesFluorodeoxyglucose F18Predictive Value of TestsRegion of interestmedicineHumansFalse Positive ReactionsRetrospective Studies18F-fluoro-2-deoxy-d-glucose 11C-labeled methionine PET imaging Active contour algorithm Biological target volume Cancer segmentationbusiness.industryRadiotherapy Planning Computer-Assisted11C-labeled methionineReproducibility of ResultsPattern recognitionGold standard (test)Cancer segmentationRadiation therapyBiological target volumePositron-Emission TomographyArtificial intelligenceTomography X-Ray ComputedbusinessSoftwareComputers in Biology and Medicine
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A differential equation approach to implicit sweeping processes

2019

International audience; In this paper, we study an implicit version of the sweeping process. Based on methods of convex analysis, we prove the equivalence of the implicit sweeping process with a differential equation, which enables us to show the existence and uniqueness of the solution to the implicit sweeping process in a very general framework. Moreover, this equivalence allows us to give a characterization of nonsmooth Lyapunov pairs and invariance for implicit sweeping processes. The results of the paper are illustrated with two applications to quasistatic evolution variational inequalities and electrical circuits.

Lyapunov functionDifferential equation01 natural scienceslaw.inventionsymbols.namesakeEvolution variational inequalitylawApplied mathematicsUniqueness0101 mathematicsEquivalence (formal languages)[MATH]Mathematics [math]MathematicsConvex analysisApplied Mathematics010102 general mathematicsNonsmooth Lyapunov pairs010101 applied mathematicsregularizationMSC: 49J40 47J20 47J22 34G25 58E35 37L45Electrical networkVariational inequalitysymbolsMoreau's sweeping processAnalysisQuasistatic process
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A model species for agricultural pest genomics: the genome of the Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae)

2018

AbstractThe Colorado potato beetle is one of the most challenging agricultural pests to manage. It has shown a spectacular ability to adapt to a variety of solanaceaeous plants and variable climates during its global invasion, and, notably, to rapidly evolve insecticide resistance. To examine evidence of rapid evolutionary change, and to understand the genetic basis of herbivory and insecticide resistance, we tested for structural and functional genomic changes relative to other arthropod species using genome sequencing, transcriptomics, and community annotation. Two factors that might facilitate rapid evolutionary change include transposable elements, which comprise at least 17% of the gen…

Male0106 biological sciences0301 basic medicineGenome Insectlcsh:Medicine01 natural sciencesGenomeNucleotide diversityInsecticide Resistancepomme de terreTRIBOLIUM-CASTANEUMlcsh:ScienceLeptinotarsaCYSTEINE PROTEINASESPhylogeny2. Zero hungereducation.field_of_studyGenomeMultidisciplinarybiologyinsecte ravageurEcologyGenètica vegetalAgricultureleptinotarsa decemlineataGenomicsS-TRANSFERASE GENESlutte contre les ravageursColeopteraOther Physical Sciencesphénotypeespèce modèleMultigene FamilyInsect ProteinsRNA InterferenceFemaleBiotechnologyAutre (Sciences du Vivant)Genome evolutiondoryphorecoleopteraEvolutionPopulationPopulationRNA-INTERFERENCEGenomicsGEOGRAPHIC POPULATIONSArticleDNA sequencingHost-Parasite InteractionsEvolution Molecular03 medical and health sciences[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]GeneticsAnimalsanalyse génomiquePest Control BiologicaleducationQH426GeneSolanum tuberosumComparative genomicsbusiness.industrychrysomelidaelcsh:RHuman GenomefungiColorado potato beetlePest controlBiology and Life SciencesMolecularGenetic VariationMolecular Sequence AnnotationBiologicalbiology.organism_classification010602 entomologyGenòmicaGenetics Population030104 developmental biologyGene Expression RegulationDROSOPHILA-MELANOGASTERPROTEINASE-INHIBITORSEvolutionary biologyTRANSPOSABLE ELEMENTSDNA Transposable Elementslcsh:QPest ControlBiochemistry and Cell BiologyPEST analysisCAENORHABDITIS-ELEGANSbusinessInsectTranscription Factors
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Natural selection mediated by seasonal time constraints increases the alignment between evolvability and developmental plasticity

2021

Abstract Phenotypic plasticity can either hinder or promote adaptation to novel environments. Recent studies that have quantified alignments between plasticity, genetic variation, and divergence propose that such alignments may reflect constraints that bias future evolutionary trajectories. Here, we emphasize that such alignments may themselves be a result of natural selection and do not necessarily indicate constraints on adaptation. We estimated developmental plasticity and broad sense genetic covariance matrices (G) among damselfly populations situated along a latitudinal gradient in Europe. Damselflies were reared at photoperiod treatments that simulated the seasonal time constraints ex…

Male0106 biological sciences0301 basic medicinelife historyOdonata01 natural sciencesG‐matrixphenotypic plasticityDivergenceEvolutionsbiologiG&#8208time constraintsdevelopmental biassopeutuminenNatural selectionluonnonvalintalatitudeAdaptation PhysiologicalBiological EvolutionOriginal ArticleFemaleSeasonsGeneral Agricultural and Biological Sciencesympäristönmuutoksetgenetic constraintsPhotoperiodevoluutioLestesBiology010603 evolutionary biology03 medical and health sciencesGeneticsAnimalsSelection GeneticAdaptationEcology Evolution Behavior and SystematicsSelection (genetic algorithm)Phenotypic plasticityEvolutionary BiologyhentosudenkorennotGenetic VariationOriginal Articlesbiology.organism_classificationmatrixEvolvability030104 developmental biologyEvolutionary biologyDevelopmental plasticityfenotyyppiAdaptation
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Inferring genetic connectivity in real populations, exemplified by coastal and oceanic atlantic cod

2018

Significance Estimates of migration are important for understanding the dynamics of natural populations. A statistic known as FST is often used to measure levels of genetic differentiation among natural populations. Equations that translate FST into estimates of migration are based on “ideal” populations, which are subject to many simplifying assumptions compared with real populations. Therefore, theoretical estimates of migration might not be realistic. We modeled populations of Atlantic cod in the North Sea and the adjacent Skagerrak region to compare how migration is related to the complexities of real populations, and how actual migration compares with predictions based on theory. Resul…

Male0106 biological sciences0301 basic medicinepopulation genetic theoryFishingTotal population010603 evolutionary biology01 natural sciences03 medical and health sciencesGenetic variationpopulation dynamicsAnimalsSelection GeneticExtreme value theorygenetic connectivityMultidisciplinaryModels GeneticEcologybiologyPopulation sizeGenetic VariationBiological Sciencesbiology.organism_classification030104 developmental biologyGadus morhuaWright’s equationfisheries managementEvolutionary biologyGenetic markerBiological dispersalAnimal MigrationFemaleAtlantic cod
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Strong reproductive barriers in a narrow hybrid zone of West-Mediterranean green toads (Bufo viridis subgroup) with Plio-Pleistocene divergence

2010

Abstract Background One key question in evolutionary biology deals with the mode and rate at which reproductive isolation accumulates during allopatric speciation. Little is known about secondary contacts of recently diverged anuran species. Here we conduct a multi-locus field study to investigate a contact zone between two lineages of green toads with an estimated divergence time of 2.7 My, and report results from preliminary experimental crosses. Results The Sicilian endemic Bufo siculus and the Italian mainland-origin B. balearicus form a narrow hybrid zone east of Mt. Etna. Despite bidirectional mtDNA introgression over a ca. 40 km North-South cline, no F1 hybrids could be found, and nu…

Male0106 biological sciencesBufo viridis hybrid zone mtDNA microsatellitesGenotypeEvolutionPopulationAllopatric speciationSettore BIO/05 - ZoologiaZoologyIntrogressionBiologyDNA Mitochondrial010603 evolutionary biology01 natural sciencesEvolution Molecular03 medical and health sciencesHybrid zoneQH359-425AnimalsCluster AnalysiseducationCrosses GeneticPhylogenyEcology Evolution Behavior and Systematics030304 developmental biologyHybridLocal adaptationCell NucleusPrincipal Component Analysis0303 health scienceseducation.field_of_studyChimeraMediterranean RegionReproductionGenetic VariationBayes TheoremSequence Analysis DNAReproductive isolationCline (biology)BufonidaeIntronsGenetics PopulationEvolutionary biologyHybridization GeneticFemaleGenetic FitnessMicrosatellite RepeatsResearch ArticleBMC Evolutionary Biology
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Successive Invasion-Mediated Interspecific Hybridizations and Population Structure in the Endangered Cichlid Oreochromis mossambicus.

2013

Hybridization between invasive and native species accounts among the major and pernicious threats to biodiversity. The Mozambique tilapia Oreochromis mossambicus, a widely used freshwater aquaculture species, is especially imperiled by this phenomenon since it is recognized by the IUCN as an endangered taxon due to genetic admixture with O. niloticus an invasive congeneric species. The Lower Limpopo and the intermittent Changane River (Mozambique) drain large wetlands of potentially great importance for conservation of O. mossambicus, but their populations have remained unstudied until today. Therefore we aimed (1) to estimate the autochthonous diversity and population structure among genet…

Male0106 biological sciencesConservation geneticsintraspecific hybridization[SDV.BA] Life Sciences [q-bio]/Animal biologyIntrogression[SDV]Life Sciences [q-bio]Endangered speciesBiodiversityLimnetic Ecologylcsh:MedicinePopulation geneticsIntroduced speciesAquaculture01 natural sciencesstructure de la populationIUCN Red Listhttp://aims.fao.org/aos/agrovoc/c_35412Amplified Fragment Length Polymorphism Analysislcsh:ScienceMozambiquePhylogenyComputingMilieux_MISCELLANEOUShybridation intraspécifiqueAnimal ManagementConservation ScienceFreshwater Ecology0303 health sciencesMultidisciplinaryEcologybiologyEcology[SDV.BA]Life Sciences [q-bio]/Animal biologyAgricultureBiodiversityGene Pool[SDV] Life Sciences [q-bio][ SDV.GEN.GPO ] Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]FemaleFish FarmingTilapiaResearch ArticleGene FlowOreochromis mossambicusEvolutionary Processesoreochromis mossambicusGenotypeMolecular Sequence DataAgro-Population EcologyGenetic admixture[SDV.BID]Life Sciences [q-bio]/BiodiversityDNA Mitochondrial010603 evolutionary biology03 medical and health sciencesRiversSpecies SpecificityGeneticsAnimalsespèce invasive14. Life underwaterAdaptationBiologyHybridizationSpecies Extinction030304 developmental biology[ SDV.BID ] Life Sciences [q-bio]/BiodiversityEvolutionary Biology[ SDE.BE ] Environmental Sciences/Biodiversity and Ecology[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]Endangered Specieslcsh:RGenetic VariationBayes Theorempopulation structureSequence Analysis DNA15. Life on landL10 - Génétique et amélioration des animauxbiology.organism_classificationGenetics PopulationHaplotypesGenetic PolymorphismHybridization Geneticlcsh:QM12 - Production de l'aquaculturehttp://aims.fao.org/aos/agrovoc/c_4964[SDE.BE]Environmental Sciences/Biodiversity and EcologyIntroduced SpeciesAnimal GeneticsAgroecologyPopulation Genetics
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Females tend to prefer genetically similar mates in an island population of house sparrows.

2014

11 pages; International audience; BACKGROUND: It is often proposed that females should select genetically dissimilar mates to maximize offspring genetic diversity and avoid inbreeding. Several recent studies have provided mixed evidence, however, and in some instances females seem to prefer genetically similar males. A preference for genetically similar mates can be adaptive if outbreeding depression is more harmful than inbreeding depression or if females gain inclusive fitness benefits by mating with close kin. Here, we investigated genetic compatibility and mating patterns in an insular population of house sparrow (Passer domesticus), over a three-year period, using 12 microsatellite mar…

Male0106 biological sciencesMate choiceOutbreeding depressionPopulationGenes MHC Class IKin selectionBiology010603 evolutionary biology01 natural sciences03 medical and health sciences[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisInbreeding depressionPasser domesticusAnimalsInbreedingMatingeducationMicrosatellitesEcology Evolution Behavior and Systematicsreproductive and urinary physiology030304 developmental biologyIslands[ SDE.BE ] Environmental Sciences/Biodiversity and Ecology0303 health scienceseducation.field_of_studyGenetic VariationMating Preference AnimalMating preferencesSexual selectionEvolutionary biologySexual selectionbehavior and behavior mechanismsExtra-pair paternityFemaleFrance[SDE.BE]Environmental Sciences/Biodiversity and EcologyMajor Histocompatibility Complex (MHC)InbreedingSparrowsResearch ArticleMicrosatellite Repeats[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Large variation in mitochondrial DNA of sexual and parthenogenetic Dahlica triquetrella (Lepidoptera: Psychidae) shows multiple origins of parthenoge…

2013

Background Obligate parthenogenesis is relatively rare in animals. Still, in some groups it is quite common and has evolved and persisted multiple times. These groups may provide important clues to help solve the ‘paradox of sex’. Several species in the Psychidae (Lepidoptera) have obligate parthenogenesis. Dahlica triquetrella is one of those species where multiple transitions to parthenogenesis are postulated based on intensive cytological and behavioural studies. This has led to the hypothesis that multiple transitions from sexuals to diploid parthenogens occurred during and after the last glacial period, followed by transitions from parthenogenetic diploids to parthenogenetic tetraploid…

Male0106 biological sciencesMitochondrial DNAEntomologyAutomixisMolecular Sequence DataParthenogenesisZoologyMothsBiologyDNA Mitochondrial010603 evolutionary biology01 natural sciencesChromosomesEvolution MolecularCOILepidoptera genitalia03 medical and health sciencesMonophylyPhylogeneticsAnimalsPhylogenyAsexualEcology Evolution Behavior and Systematics030304 developmental biology0303 health sciencesfylogeniaTetraploidObligateCOIIGenetic VariationAsexual; Automixis; COI; COII; Phylogeny; TetraploidParthenogenesisDiploidyHaplotypesEvolutionary biologyMolecular phylogeneticsFemaleResearch Article
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FITNESS TRADE-OFFS MEDIATED BY IMMUNOSUPPRESSION COSTS IN A SMALL MAMMAL

2009

International audience; Trade-offs are widespread between life-history traits, such as reproduction and survival. However, their underlying physiological and behavioral mechanisms are less clear. One proposed physiological factor involves the trade-off between investment in male reproductive effort and immunity. Based on this hypothesis, we investigated differences in fitness between artificially selected immune response bank vole groups, Myodes glareolus. Significant heritability of immune response was found and a correlated response in testosterone levels to selection on immune function. Male reproductive effort, reproductive success, and survival of first generation offspring were assess…

Male0106 biological sciencesOffspringZoology010603 evolutionary biology01 natural sciencesImmune systemImmunityGenetic variationImmune ToleranceGeneticsAnimalsTestosteroneEcology Evolution Behavior and Systematics[SDV.EE]Life Sciences [q-bio]/Ecology environmentGeneticsImmunity CellularbiologyReproductive successArvicolinaeReproductionHeritabilitybiology.organism_classification010601 ecologyBank vole[SDV.EE] Life Sciences [q-bio]/Ecology environmentSexual selectionAntibody FormationFemaleGeneral Agricultural and Biological Sciences
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