Search results for "VECTOR"
showing 10 items of 2660 documents
BIFOCAL PAIRS OF IMAGES FOR LOW-COST SURVEY IN CLOSE RANGE PHOTOGRAMMETRY
2019
Abstract. This paper present a method for close range photogrammetry based on an camera positioning scheme in which two cameras capture an equal portion of an object at the same scale, but have different focal lengths and camera-to-object distances. This scheme is alternative to the stereoscopic scheme and is associated with a system of equations which permits one to calculate first the relief displacement of points on a photograph and then their relief relative to a reference plane. The obtained relief and relief displacement values can be used to produce low-cost orthophotographs by using software for image processing, which doesn’t need to be dedicated, but has to provide measurement and…
Reconstruction of urban sites from photos
2019
Abstract. This paper reports the results of an experiment that aims at the virtual reconstruction of a urban site that has been partially reshaped during the 20th century; the reconstruction process is based on period photos. The chosen case study is the eldest harbour of Palermo, named ‘Cala’; the site was bombed during World War II and new buildings took the place of the ruined ones. Two period photos, taken from an aircraft, document the buildings that were destroyed by bombs. The 3D restitution process used the ‘inverse’ projection from period photos (2D) to the virtual space (3D) ; the first step was therefore addressed to the calculation of the inner parameters (focal length, principa…
All-Fiber Laser With Intracavity Acousto-Optic Dynamic Mode Converter for Efficient Generation of Radially Polarized Cylindrical Vector Beams
2017
We report an all-fiber laser that emits a radially polarized cylindrical vector beam (CVB) at 1 μm based on an intracavity acousto-optic mode converter. We efficiently generate the CVB, taking advantage of the acousto-optic coupling from the HE11 mode to the TM01 mode in a two-mode fiber. The laser can be switched from emitting a Gaussian-like beam to a radially polarized CVB. Radially polarized CVBs with modal and polarization purities >98% and a maximum power of 65 mW were generated.
An updated insight into the Sialotranscriptome of Triatoma infestans: developmental stage and geographic variations
2014
Background Triatoma infestans is the main vector of Chagas disease in South America. As in all hematophagous arthropods, its saliva contains a complex cocktail that assists blood feeding by preventing platelet aggregation and blood clotting and promoting vasodilation. These salivary components can be immunologically recognized by their vector's hosts and targeted with antibodies that might disrupt blood feeding. These antibodies can be used to detect vector exposure using immunoassays. Antibodies may also contribute to the fast evolution of the salivary cocktail. Methodology Salivary gland cDNA libraries from nymphal and adult T. infestans of breeding colonies originating from different loc…
Advanced radar-interpretation of InSAR time series for mapping and characterization of geological processes
2011
Abstract. We present a new post-processing methodology for the analysis of InSAR (Synthetic Aperture Radar Interferometry) multi-temporal measures, based on the temporal under-sampling of displacement time series, the identification of potential changes occurring during the monitoring period and, eventually, the classification of different deformation behaviours. The potentials of this approach for the analysis of geological processes were tested on the case study of Naro (Italy), specifically selected due to its geological setting and related ground instability of unknown causes that occurred in February 2005. The time series analysis of past (ERS1/2 descending data; 1992–2000) and current…
Bovine herpesvirus 4-based vector delivering the full length xCT DNA efficiently protects mice from mammary cancer metastases by targeting cancer ste…
2018
Despite marked advancements in its treatment, breast cancer is still the second leading cause of cancer death in women, due to relapses and distal metastases. Breast cancer stem cells (CSCs), are a cellular reservoir for recurrence, metastatic evolution and disease progression, making the development of novel therapeutics that target CSCs, and thereby inhibit metastases, an urgent need. We have previously demonstrated that the cystine-glutamate antiporter xCT (SLC7A11), a protein that was shown to be overexpressed in mammary CSCs and that plays a key role in the maintenance of their redox balance, self-renewal and resistance to chemotherapy, is a potential target for mammary cancer immunoth…
The Immunology of Zoonotic Infections
2012
Zoonotic infections are in general defined as infections transmitted from animal to man (and less frequently vice versa), either directly (through contact or contact with animal products) or indirectly (through an intermediate vector as an arthropod or an insect) [1]. Although the burden of zoonotic infections worldwide is major, both in terms of immediate and long-term morbidity and mortality [2, 3] and in terms of emergence/reemergence and socioeconomical, ecological, and political correlations [4], scientific and public health interest and funding for these diseases remain relatively minor. Zoonoses include diseases induced by diverse pathogens (bacteria, viruses, fungi, and parasites), …
Immunological Monitoring to Rationally Guide AAV Gene Therapy
2013
Recent successes with adeno-associated virus (AAV)-based gene therapies fuel the hope for new treatments for hereditary diseases. Pre-existing as well as therapy-induced immune responses against both AAV and the encoded transgenes have been described and may impact on safety and efficacy of gene-therapy approaches. Consequently, monitoring of vector- and transgene-specific immunity is mandated and may rationally guide clinical development. Next to the humoral immune response, the cellular response is central in our understanding of the host reaction in gene therapy. But in contrast to the monitoring of antibodies, which has matured over many decades, sensitive and robust monitoring of T cel…
A focused ultrasound treatment system for moving targets (part I): generic system design and in-silico first-stage evaluation
2017
Abstract Background Focused ultrasound (FUS) is entering clinical routine as a treatment option. Currently, no clinically available FUS treatment system features automated respiratory motion compensation. The required quality standards make developing such a system challenging. Methods A novel FUS treatment system with motion compensation is described, developed with the goal of clinical use. The system comprises a clinically available MR device and FUS transducer system. The controller is very generic and could use any suitable MR or FUS device. MR image sequences (echo planar imaging) are acquired for both motion observation and thermometry. Based on anatomical feature tracking, motion pr…
Impact of the terrestrial reference frame on the determination of the celestial reference frame.
2022
Currently three up-to-date Terrestrial Reference Frames (TRF) are available, the ITRF2014 from IGN, the DTRF2014 from DGFI-TUM, and JTRF2014 from JPL. All use the identical input data of space-geodetic station positions and Earth orientation parameters, but the concept of combining these data is fundamentally different. The IGN approach is based on the combination of technique solutions, while the DGFI is combining the normal equation systems. Both yield in reference epoch coordinates and velocities for a global set of stations. JPL uses a Kalman filter approach, realizing a TRF through weekly time series of geocentric coordinates. As the determination of the CRF is not independent of the T…