Search results for "VIP"

showing 10 items of 223 documents

Insights into the Structure of the Vip3Aa Insecticidal Protein by Protease Digestion Analysis

2017

Vip3 proteins are secretable proteins from Bacillus thuringiensis whose mode of action is still poorly understood. In this study, the activation process for Vip3 proteins was closely examined in order to better understand the Vip3Aa protein stability and to shed light on its structure. The Vip3Aa protoxin (of 89 kDa) was treated with trypsin at concentrations from 1:100 to 120:100 (trypsin:Vip3A, w:w). If the action of trypsin was not properly neutralized, the results of SDS-PAGE analysis (as well as those with Agrotis ipsilon midgut juice) equivocally indicated that the protoxin could be completely processed. However, when the proteolytic reaction was efficiently stopped, it was revealed t…

0301 basic medicineProteasesHealth Toxicology and MutagenesisSize-exclusion chromatographyBeta sheetBacillus thuringiensislcsh:MedicineBiologyToxicologyCleavage (embryo)ArticleProtein Structure Secondary03 medical and health sciencestrypsin inhibitorsBacterial ProteinsSDS-PAGE artefactprotease stabilitymedicinebacterial secreted proteinsAnimalsTrypsinMode of actionProtein secondary structureVip proteinsIntestinal Secretionslcsh:Rtoxin activationVip proteins; bacterial secreted proteins; toxin activation; proteolytic activation; trypsin inhibitors; <i>Bacillus thuringiensis</i>; SDS-PAGE artefact; protease stabilityTrypsinMolecular biologyLepidoptera030104 developmental biologyBiochemistryproteolytic activationLarvaProteolysisPeptidesAlpha helixmedicine.drugToxins
researchProduct

Corrigendum: Psychological Effects of a 1-Month Meditation Retreat on Experienced Meditators: The Role of Non-attachment

2016

Background: There are few studies devoted to assessing the impact of meditation-intensive retreats on the well-being, positive psychology, and personality of experienced meditators. We aimed to assess whether a 1-month Vipassana retreat: (a) would increase mindfulness and well-being; (b) would increase prosocial personality traits; and (c) whether psychological changes would be mediated and/or moderated by non-attachment. Method: A controlled, non-randomized, pre-post-intervention trial was used. The intervention group was a convenience sample (n = 19) of experienced meditators who participated in a 1-month Vipassana meditation retreat. The control group (n = 19) comprised matched experienc…

050103 clinical psychologyMindfulnessmeditationmedia_common.quotation_subjectpositive psychology050105 experimental psychologyVipassanawellbeingPositive psychologyretreatPsychologyPersonality0501 psychology and cognitive sciencesMeditationBig Five personality traitsGeneral PsychologyOriginal Researchmedia_commonWellbeing05 social sciencesCooperativenessCorrectionModerationMeditacióMeditationpersonalityTemperamentPositive psychologyPsychologyRetreatClinical psychologyPersonality
researchProduct

Mining of new insecticidal protein genes plus determination of the insecticidal spectrum and mode of action of Bacillus thuringiensis Vip3Ca protein

2019

Bacillus thuringiensis és un bacteri que pertany al grup de Bacillus cereus i produeix una gran varietat de proteïnes insecticides juntament amb altres factors de virulència que contribueixen a la seva patogenicitat. Bacillus thuringiensis s'ha considerat com el agent bioinsecticida amb més èxit durant el segle passat. Actualment, és àmpliament utilitzat com agent microbià per a les principals plagues d'insectes com a formulat (selecció de aïllats de B. thuringiensis escollits per la seua combinació de proteïnes insecticides present en el cristall parasporal) o mitjançant l’expressió de les proteïnes insecticides (cultius Bt) en plantes d’interès agronòmic (dacsa, cotó, soja, etc.). En quan…

:CIENCIAS AGRARIAS::Fitopatología [UNESCO]Vip3 proteinsCrop protectionBacillus thuringiensis:CIENCIAS AGRARIAS::Agroquímica::Insecticidas [UNESCO]UNESCO::CIENCIAS AGRARIAS::FitopatologíaUNESCO::CIENCIAS AGRARIAS::Agroquímica::Insecticidas
researchProduct

Feodālisma problēmas Baltijā

1988

Rakstu problemātika ir daudzveidīga un aptver visu feodālisma vēstures laikmetu Baltijā. Krājumā ietverti ari avotpētnieciska (par Sakša Gramatiķa "Gesta Danorum") un historiogrāfiska (par R.Viperu) rakstura darbi.

:HUMANITIES and RELIGION::History and philosophy subjects::History subjects::History [Research Subject Categories]Sakša Gramatiķa "Gesta Danorum"Vipers RobertsFeodālismsRīgas vēstureLivonijas vēstureLatvijas vēstureLatvijas historiogrāfija
researchProduct

El carácter como predictor de trastornos de la personalidad en adictos: la tipología caracterial de Cloninger y su abordaje psicosocial

2007

El presente estudio aborda las relaciones de las dimensiones caracteriales del modelo de Cloninger con los trastornos de la personalidad. Se obtiene una muestra de sujetos (N=565) que inician tratamiento por conductas adictivas en un centro ambulatorio (CAD 4 San Blas, Instituto de Adicciones, Madrid Salud), y cumplimentan el TCI-R, el MCMI-II, el VIP y el CCE-R. Según los criterios de Cloninger y, mediante análisis discriminante, son clasificados en los diferentes tipos caracteriales. Se comparan éstos con los encontrados en una muestra de población general (N=114), encontrándose que mientras en éste grupo predomina el tipo Equilibrado, en el grupo de adictos predominan los tipos Desorgani…

:PSICOLOGÍA::Psicofarmacología [UNESCO]:PSICOLOGÍA [UNESCO]UNESCO::PSICOLOGÍAUNESCO::PSICOLOGÍA::PsicofarmacologíaPersonalidad Carácter Evaluación Trastornos de la Personalidad TCI-R MCMI-II VIP.
researchProduct

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

2012

BACKGROUND: Some patients with severe asthma have recurrent asthma exacerbations associated with eosinophilic airway inflammation. Early studies suggest that inhibition of eosinophilic airway inflammation with mepolizumab-a monoclonal antibody against interleukin 5-is associated with a reduced risk of exacerbations. We aimed to establish efficacy, safety, and patient characteristics associated with the response to mepolizumab. METHODS: We undertook a multicentre, double-blind, placebo-controlled trial at 81 centres in 13 countries between Nov 9, 2009, and Dec 5, 2011. Eligible patients were aged 12-74 years, had a history of recurrent severe asthma exacerbations, and had signs of eosinophil…

AdultMalemedicine.medical_specialtyAdolescentPlacebo-controlled studyFevipiprantAntibodies Monoclonal HumanizedPlaceboLebrikizumabDrug Administration ScheduleLeukocyte CountYoung Adultchemistry.chemical_compoundDouble-Blind MethodReslizumabInternal medicineSecondary PreventionmedicineHumansAnti-Asthmatic AgentsPulmonary EosinophiliaChildGlucocorticoidsAgedAsthmaDose-Response Relationship Drugbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseBenralizumabAsthmaEosinophilsTreatment OutcomechemistryPhysical therapyDrug Therapy CombinationFemaleInterleukin-5businessMepolizumabmedicine.drugThe Lancet
researchProduct

Endothelin receptors mediating contraction in goat cerebral arteries

1993

1. The aim of the present study was to identify the subtype of receptor mediating contraction to endothelin-1 and sarafotoxin S6b in goat isolated middle cerebral arteries. 2. Endothelin-1, endothelin-2 and endothelin-3 contracted cerebral arteries in a concentration-dependent manner. Although the three peptides were full agonists, the order of potency was endothelin-1 = endothelin-2 > endothelin-3, with a relative potency of endothelin-1 and endothelin-2 versus endothelin-3 of approximately 280. Sarafotoxin S6b induced concentration-dependent contractions with lower potency than endothelin-1/endothelin-2, higher potency than endothelin-3 and a higher maximum response than the three endothe…

Agonistmedicine.hormoneSerotoninmedicine.medical_specialtymedicine.drug_classMolecular Sequence DataCerebral arteriesViper VenomsIn Vitro TechniquesPeptides Cycliccomplex mixturesMuscle Smooth VascularEndothelinschemistry.chemical_compoundInternal medicinemedicine.arterymedicineAnimalsVasoconstrictor AgentsPotencyAmino Acid SequencePharmacologyBQ-123Receptors EndothelinChemistryEndothelinsGoatsCerebral ArteriesEndocrinologyMiddle cerebral arterycardiovascular systemFemalemedicine.symptomEndothelin receptorVasoconstrictionResearch ArticleMuscle ContractionBritish Journal of Pharmacology
researchProduct

Data from: Effects of undergrowth removal and edge proximity on ground beetles and vascular plants in urban boreal forests

2019

Urban forests are regularly managed for human safety and aesthetic reasons, but they are crucial habitat for many species. Removals of undergrowth occur commonly in these forests, yet the ecological consequences of these operations are poorly understood. We sampled ground beetles (Coleoptera, Carabidae) and vascular plants along 20-m edge gradients in Finnish urban forests, in five stands treated 0.5−2.5 years earlier with undergrowth removal and in five untreated stands. We hypothesized that undergrowth removal and edge proximity would benefit opportunistic and open-habitat species, whereas shady-habitat species would be affected negatively. (1) Regarding carabids, diversity and evenness i…

Agrostis capillarisRichnessDryopteris filix-masMilium effusumNardus strictaRubus idaeusVaccinium myrtillusLeistus terminatusCarex canescensLinnaea borealisOxalis acetocellaLuzula luzuloidesParis quadrifoliaLonicera xylosteumPterostichus nigerGeranium sylvaticumCalamagrostis arundinaceusmedicine and health carePatrobus assimilisTaraxacum spFragaria vescaArtemisia vulgarisPterostichus diligensCalathus micropterusPterostichus oblongopunctatusCalathus melanocephalusPhleum pretenseDeschampsia flexuosaHypericum maculatumViola rivinianaPterostichus melanariusLife SciencesPterostichus nigritaActaea spicataUrtica dioicaMelampyrum pretenseEquisetum pretenseFestuca ovinaSorbus aucupariaRubus saxatilisAnisodactylus binotatusMedicineMelica nutansCarabidaeAmara lunicollisAnthriscus sylvestrisLuzula pilosaTrechus secalisPterostichus strenuousCarabus hortensisHarpalus tardusedge effectGalium albumVeronica officinalisBadister lacertosusAlchemilla spQuaternaryCychrus caraboidesDryopteris carthusianaMaianthemum bifoliumPatrobus atrorufusTrechus rivularisNotiophilus biguttatusGeum urbanumundergrowthVaccinium vitis-idaeaMelampyrum sylvaticumGymnocarpium dryopterisDeschampsia cespitosaLoricera pilicornisCarex acutaAmara communisRanunculus repensConvallaria majalisAthyrium filix-feminaRibes rubrumHoloceneCirsium arvensePoa chaixiiAegopodium podagrariaTrientalis europaeaLeistus ferrugineusEquisetum sylvaticumRanunculus acrisEpilobium montanumAcer platanoidesScrophularia nodosaHarpalus laevipesUrtica urensCarabus nemoralisHieracium sylvaticaCampanula rotundifoliaSynuchus vivalisEpilobium angustifoliumVeronica chamaedrys
researchProduct

Super omnias veritas. Latvijas vēsturnieku darbs un likteņi

2018

Latvijas Universitātes (LU) Bibliotēkas stenda referāts prezentēts Latvijas vēsturnieku 2. kongresā un sniedz ieskatu LU Bibliotēkas nozīmīgajā darbā LU intelektuālo sasniegumu un kultūrvēsturiskā mantojuma saglabāšanā un popularizēšanā. Stenda referāts iepazīstina ar LU Bibliotēkas vienu no pētnieciskās darbības virzieniem - virtuālajām izstādēm, kas veltītas augstskolas vēsturei, sasniegumiem un ievērojamām personībām zinātnē.

Aleksandra Rolovavirtuālās izstādesLatvijas Vēstures institūta žurnālsLatvijas Universitātes BibliotēkaArnolds SpekkeHeinrihs StrodsRoberts VippersFrancis Balodis
researchProduct

Feasibility of hyperspectral vegetation indices for the detection of chlorophyll concentration in three high Arctic plants: Salix polaris, Bistorta v…

2018

Remote sensing, which is based on a reflected electromagnetic spectrum, offers a wide range of research methods. It allows for the identification of plant properties, e.g., chlorophyll, but a registered signal not only comes from green parts but also from dry shoots, soil, and other objects located next to the plants. It is, thus, important to identify the most applicable remote-acquired indices for chlorophyll detection in polar regions, which play a primary role in global monitoring systems but consist of areas with high and low accessibility. This study focuses on an analysis of in situ-acquired hyperspectral properties, which was verified by simultaneously measuring the chlorophyll conc…

Arctic plants010504 meteorology & atmospheric sciences0211 other engineering and technologiesRed edge:Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480 [VDP]02 engineering and technologyPlant Scienceremote sensing indices01 natural sciencesNormalized Difference Vegetation Indexchemistry.chemical_compoundremote sensinglcsh:BotanySalix polarisASD FieldSpecDryas octopetalaArctic vegetation021101 geological & geomatics engineering0105 earth and related environmental sciencesbiologyVegetationbiology.organism_classificationBistorta viviparalcsh:QK1-989chemistryChlorophyllEnvironmental sciencePhysical geographyActa Societatis Botanicorum Poloniae
researchProduct