Search results for "VIRUS"

showing 10 items of 5024 documents

Phylogeography and Molecular Evolution of Potato virus Y

2012

Potato virus Y (PVY) is an important plant pathogen, whose host range includes economically important crops such as potato, tobacco, tomato, and pepper. PVY presents three main strains (PVYO, PVYN and PVYC) and several recombinant forms. PVY has a worldwide distribution, yet the mechanisms that promote and maintain its population structure and genetic diversity are still unclear. In this study, we used a pool of 77 complete PVY genomes from isolates collected worldwide. After removing the effect of recombination in our data set, we used Bayesian techniques to study the influence of geography and host species in both PVY population structure and dynamics. We have also performed selection and…

0106 biological sciencesEvolutionary GeneticsAmino-acid sitesSelective constraintsPotyviruslcsh:Medicine01 natural sciencesAmino-Acid SitesRecombinant strainPlant RNA virusesNegative selectionMaximum-Likelihoodlcsh:Sciencepathologie végétaleSelective ConstraintsPhylogenyGenetics0303 health sciencesCoat proteinMultidisciplinaryNatural selectionVegetal BiologybiologyEcologyGenetic-structurePotyvirusfood and beveragesEuropePhylogeneticsVenous necrosisPhylogeographyPotato virus YBiogeographyVenous NecrosisSequence AnalysisResearch ArticlePlant RNA VirusesGenome ViralMicrobiologyEvolution Molecular03 medical and health sciencesGenetic-StructureMolecular evolutionVirologyMosaic-virus[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyEvolutionary SystematicsBiology030304 developmental biologySolanum tuberosumGenetic diversityEvolutionary BiologyMosaic virusHost (biology)Maximum-likelihoodlcsh:RComputational Biologyvirus à de la pomme de terreBayes Theoremlégumebiology.organism_classificationMutational analysisMosaic-VirusMutational AnalysisEvolutionary EcologyRecombinant StrainNorth Americalcsh:QBiologie végétalePopulation Genetics010606 plant biology & botany
researchProduct

Genetic structure and molecular variability of grapevine fanleaf virus in sicily

2021

Grapevine fanleaf virus (GFLV) is one of the main causes of grapevine fanleaf degeneration disease (GFDD) and is present in almost all areas where grapevine is cultivated. In this work, we ascertained the presence and spread of GFLV in different commercial vineyards in four Sicilian provinces (Italy), and its genetic structure and molecular variability were studied. In detail, a total of 617 grapevine samples of 11 autochthonous grapevine cultivars were collected in 20 commercial vineyards. Preliminary screening by serological (DAS-ELISA) and molecular (RT-PCR) analyses for ArMV (arabis mosaic virus) and GFLV detection were conducted. Results obtained showed the absence of ArMV in all the s…

0106 biological sciencesGFLVAgriculture (General)molecular variabilityGFLV; grapevine disease; molecular variability; DAS-ELISA; RT-PCR; phylogenetic analysisRT-PCRPlant Science01 natural sciencesS1-972Arabis mosaic virus03 medical and health sciencesCultivar030304 developmental biology0303 health sciencesPhylogenetic treebiologyphylogenetic analysisSettore AGR/12 - Patologia VegetaleGrapevine fanleaf virusbiology.organism_classificationlanguage.human_languageSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeHorticulturegrapevine diseaseGenetic structurelanguageDAS-ELISAAgronomy and Crop ScienceSicilian010606 plant biology & botanyFood Science
researchProduct

Virus epidemics can lead to a population-wide spread of intragenomic parasites in a previously parasite-free asexual population

2014

Sexual reproduction is problematic to explain due to its costs, most notably the twofold cost of sex. Yet, sex has been suggested to be favourable in the presence of proliferating intragenomic parasites given that sexual recombination provides a mechanism to confine the accumulation of deleterious mutations. Kraaijeveld et al. compared recently the accumulation of transposons in sexually and asexually reproducing lines of the same species, the parasitoid wasp Leptopilina clavipes. They discovered that within asexually reproducing wasps, the number of gypsy-like retrotransposons was increased fourfold, whereas other retrotransposons were not. Interestingly, gypsy-like retrotransposons are cl…

0106 biological sciencesGene Transfer HorizontalRetroelementsEvolution of sexual reproductionPopulationEndogenous retrovirusRetrotransposonModels Biological010603 evolutionary biology01 natural sciencesGenetic recombinationVirusParasitoid wasp03 medical and health sciencesReproduction AsexualGeneticsComputer SimulationeducationEcology Evolution Behavior and Systematics030304 developmental biologyGenetics0303 health scienceseducation.field_of_studybiologyEndogenous Retrovirusesbiology.organism_classificationSexual reproductionGenetics Populationta1181Molecular Ecology
researchProduct

The discovery, distribution and diversity of DNA viruses associated withDrosophila melanogasterin Europe

2020

AbstractDrosophila melanogasteris an important model for antiviral immunity in arthropods, but very few DNA viruses have been described from the family Drosophilidae. This deficiency limits our opportunity to use natural host-pathogen combinations in experimental studies, and may bias our understanding of theDrosophilavirome. Here we report fourteen DNA viruses detected in a metagenomic analysis of approximately 6500 pool-sequencedDrosophila, sampled from 47 European locations between 2014 and 2016. These include three new Nudiviruses, a new and divergent Entomopox virus, a virus related toLeptopilina boulardifilamentous virus, and a virus related toMusca domesticasalivary gland hypertrophy…

0106 biological sciencesGenetics0303 health sciencesbiologyvirusesRNARNA virusDNA virusbiology.organism_classification010603 evolutionary biology01 natural sciencesVirus3. Good health03 medical and health sciencesDrosophilidaeHuman viromeDrosophila melanogasterDrosophila030304 developmental biology
researchProduct

Wild

2021

Graphical abstract

0106 biological sciencesGermplasmPhytochemistryTPCC total phenolic contentElderberry flowerISSR inter-simple sequence repeatElderberry fruitIC50 the half maximal inhibitory concentrationBerrySambucus nigra01 natural sciencesArticleTFC total flavonoid contentDW dry weightSARS-CoV2 severe acute respiratory syndrome coronavirus 2Rutinchemistry.chemical_compoundBotanyELISA enzyme linked immunosorbent assayCultivarAntiviralComputingMethodologies_COMPUTERGRAPHICSGenetic diversityACE2 angiotensin converting enzyme 2biology010405 organic chemistryPVPP polyvinylpyrrolidoneSambucus nigra L.biology.organism_classification0104 chemical scienceschemistryHPLC high-performance liquid chromatographyTEAC trolox equivalent anti-radical capacityGene poolAgronomy and Crop Science010606 plant biology & botanyBinding domainIndustrial crops and products
researchProduct

Spread of tomato brown rugose fruit virus in sicily and evaluation of the spatiotemporal dispersion in experimental conditions

2020

Tomato brown rugose fruit virus (ToBRFV) is an emerging pathogen that causes severe disease in tomato (Solanum lycopersicum L.) crops. The first ToBRFV outbreak in Italy occurred in 2018 in several Sicilian provinces, representing a serious threat for tomato production. In the present work, the spatiotemporal displacement of ToBRFV in Sicily was evaluated, analyzing a total of 590 lots of tomato seed, 982 lots of plantlets from nurseries and 100 commercial greenhouses. Furthermore, we investigated the ToBRFV spreading dynamic in a greenhouse under experimental conditions. Results showed several aspects related to ToBRFV dispersion in protected tomato crops. In detail, an important decrease …

0106 biological sciencesGreenhouseTomato brown rugose fruit virusBiology01 natural sciencesToBRFV epidemiologyPlantletCroplcsh:Agriculture03 medical and health sciencesEmerging pathogenTomato seed030304 developmental biology0303 health sciencesfungilcsh:SOutbreakfood and beveragesSettore AGR/12 - Patologia VegetaleDispersionbiology.organism_classificationHorticultureEmerging pathogenSolanumAgronomy and Crop Science010606 plant biology & botany
researchProduct

Preferential induction of 20S proteasome subunits during elicitation of plant defense reactions: towards the characterization of "plant defense prote…

2003

Plants have evolved efficient mechanisms to resist pathogens. The earliest defense response is the hypersensitive response (HR) considered as the main step leading to plant systemic acquired resistance (SAR) that protects the whole plant against a large spectrum of pathogens. We showed previously that elicitation of defense reactions in tobacco cells by cryptogein, a proteinaceous elicitor of plant defense reactions, leads to a rapid and differential accumulation of transcripts corresponding to genes encoding defense-induced (din) subunits of 20S proteasome: beta1din, alpha3din and alpha6din.Here, expression of these three subunits was investigated by Northern blotting and by Western blotti…

0106 biological sciencesHypersensitive responseProteasome Endopeptidase Complex[SDV]Life Sciences [q-bio]Protein subunitBlotting WesternGene ExpressionBiology01 natural sciencesBiochemistryMixed Function OxygenasesFungal Proteins03 medical and health sciencesMultienzyme ComplexesTobaccoPlant defense against herbivoryElectrophoresis Gel Two-DimensionalNorthern blotComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesAlgal ProteinsProteinsCell BiologyBlotting NorthernMolecular biologyCell biologyElicitor[SDV] Life Sciences [q-bio]BlotPlant LeavesTobacco Mosaic VirusCysteine EndopeptidasesProteasomeEnzyme InductionREPONSE DE LA PLANTESystemic acquired resistance010606 plant biology & botanyPeptide HydrolasesThe international journal of biochemistrycell biology
researchProduct

Genomic Analysis and Lineage Identification of SARS-CoV-2 Strains in Migrants Accessing Europe Through the Libyan Route

2021

Many African countries, representing the origin of the majority of refugees, asylum-seekers, and other migrants, toward regions bordering on the Mediterranean area, are experiencing sustained local transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Sicily is one of the main entry gates of migrants crossing into Europe. We conducted a pilot study, based on the full-genome sequencing of SARS-CoV-2 strains isolated from migrants coming to Sicily by crossing the Mediterranean Sea, with the aim to investigate the viral genome polymorphism and to describe their genetic variations and the phylogenetic relationships. On June 21, a nongovernmental organization vessel rescu…

0106 biological sciencesLineage (genetic)virusesPilot ProjectsGenomicsLibyaasylum-seeker010603 evolutionary biology01 natural scienceslaw.invention03 medical and health sciencesMediterranean seaPhylogeneticslawMediterranean SeaHumansGenetic variabilitySicilyPhylogeny030304 developmental biologyTransients and Migrants0303 health sciencesPhylogenetic treeSARS-CoV-2lcsh:Public aspects of medicinefungiPublic Health Environmental and Occupational HealthCOVID-19virus diseaseslcsh:RA1-1270Genomicsmolecular surveillanceBrief Research Reportlanguage.human_languageEuropemigrantGeographyTransmission (mechanics)Evolutionary biologyNGSAfricalanguagePublic HealthSicilianFrontiers in Public Health
researchProduct

Hantavirus infections in fluctuating host populations: the role of maternal antibodies.

2010

Infected females may transfer maternal antibodies (MatAbs) to their offspring, which may then be transiently protected against infections the mother has encountered. However, the role of maternal protection in infectious disease dynamics in wildlife has largely been neglected. Here, we investigate the effects of Puumala hantavirus (PUUV)-specific MatAbs on PUUV dynamics, using 7 years' data from a cyclic bank vole population in Finland. For the first time to our knowledge, we partition seropositivity data from a natural population into separate dynamic patterns for MatAbs and infection. The likelihood of young of the year carrying PUUV-specific MatAbs during the breeding season correlated p…

0106 biological sciencesMaleOrthohantavirusHantavirus InfectionsPopulationPrevalenceZoologyAntibodies Viral010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyRodent Diseases03 medical and health sciencesPregnancySeroepidemiologic StudiesSeasonal breederAnimalseducationFinlandResearch Articles030304 developmental biologyGeneral Environmental ScienceHantavirus0303 health scienceseducation.field_of_studyGeneral Immunology and MicrobiologybiologySin Nombre virusArvicolinaeBody WeightGeneral Medicinebiology.organism_classificationBank voleNatural population growthAnimals NewbornImmunologyRegression AnalysisFemaleSeasonsGeneral Agricultural and Biological SciencesHantavirus InfectionImmunity Maternally-AcquiredProceedings. Biological sciences
researchProduct

Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA…

2020

Genetic variation is the fuel of evolution, with standing genetic variation especially important for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of genetic variation in natural populations have been challenging, as comprehensive sampling is logistically difficult, and sequencing of entire populations costly. Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster. Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, ide…

0106 biological sciencesMaleincipient sexual isolationQH301 BiologyAcclimatizationADNGenome Insect01 natural sciencesPopulation genomicsAdaptation; Clines; Demography; Population genomics; Selection; SNPs; Structural variants; Acclimatization; Altitude; Animals; DNA Viruses; Drosophila melanogaster; Europe; Genome Mitochondrial; Haplotypes; Insect Viruses; Male; Phylogeography; Polymorphism Single Nucleotide; Genome Insect; Genomic Structural Variation; Microbiota; Selection GeneticSDG 13 - Climate ActionComputingMilieux_MISCELLANEOUSeducation.field_of_study0303 health sciencesAltitude[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]PE&RCgeneettinen muunteluPhylogeographyDrosophila melanogasterLaboratory of GeneticsTransposable elementnorth-americanmahlakärpäsetSettore BIO/18 - GENETICAselectionLaboratorium voor Erfelijkheidsleeramino-acid polymorphism03 medical and health sciencesGeneticGeneticsAdaptation demographyMicrobiomeAdaptationPolymorphismeducationDrosophilaMolecular BiologySelectionEcology Evolution Behavior and SystematicsDemography[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]DNAchemistryEvolutionary biologyGenome MitochondrialGenomic Structural Variationinversion in(3r)payneAdaptationPopulation genomicsStructural variantsGenètica[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosisadaptation demographyCandidate genenucleotide polymorphismAcademicSubjects/SCI01180chemistry.chemical_compoundMelanogaster2. Zero hungerGenomebiologyMicrobiotaSingle NucleotideClinesclinesMitochondrialEuropepopulaatiogenetiikkatransposable elementsDrosophila melanogasterSNPsnatural-populationspopulation genomicsPopulationnext-generationDrosòfila melanogasterInsect Viruses010603 evolutionary biologyPolymorphism Single NucleotideQH301latitudinal clineGenetic variationAnimalsSelection GeneticSelection (genetic algorithm)DiscoveriesLocal adaptation030304 developmental biologylife-historyAcademicSubjects/SCI01130DNA Virusesstructural variantsDASbiology.organism_classificationHaplotypes13. Climate actionperimä[SDE.BE]Environmental Sciences/Biodiversity and EcologyInsectDNAMolecular Biology and Evolution
researchProduct