Search results for "VISION"
showing 10 items of 5066 documents
A Bottleneck Model of Imaging Systems for Digital Angiocardiography
1988
Some ten years ago, the performance of real-time digital subtraction angiocardiography was demonstrated for the first time [1]. Subtraction became in the years after 1980 nearly synonymous with digital angiography [2–4]. This image enhancement technique was certainly very efficient in paving the way for the digital approach to imaging. Relatively simple processors and memory structures could perform subtraction methods with some degree of success. However, even in that early stage, it was clear to many of those involved in the technical developments and in early clinical evaluations that subtraction was only one of many features that would motivate the change from traditional film technique…
Kinetic analysis of functional images: The case for a practical approach to performance prediction
1999
We present the first parallel medical application for the analysis of dynamic positron emission tomography (PET) images together with a practical performance model. The parallel application may improve the diagnosis for a patient (e. g. in epilepsy surgery) because it enables the fast computation of parametric images on a pixed level as opposed to the traditionally used region of interest (ROI) approach which is applied to determine an average parametric value for a particular anatomic region of the brain. We derive the performance model from the application context and show its relation to abstract machine models. We demonstrate the accuracy of the model to predict the runtime of the appli…
Clustering Algorithms for MRI
1991
Magnetic Resonance Imaging (MRI) plays a relevant role in the design of systems for computer assisted diagnosis. MR-images are multi-dimensional in nature; physicians have to combine several perceptual information images to perform the tissue classification needed for diagnosis. Automatic clustering methods help to discriminate relevant features and to perform a preliminary segmentation of the image; it can guide the final manual classification of body-tissues. Three clustering techniques and their integration in a MRI-system are described. Their performance and accuracy was evaluated on synthetic and real image-data. A comparison of our approach with the tissue-classification done by a rad…
Digital Acquisition and Processing of Video Angiocardiograms
1986
Angiocardiographic diagnosis is still mainly based on the visual assessment of radiographic projection images recorded on photographic film. Considerable amounts of contrast material have to be selectively injected into the circulation in order to make the regions of diagnostic relevance visible in the superposition of the shadows of tissue and bone structures displayed in these transmission images. In addition, selective angiocardiography requires exact positioning of the catheter, a time-consuming procedure which is not without risk. The processing of the angiographie films obtained is difficult to maintain at a constant high quality level, and this introduces an disadvantageous delay bet…
Real and simulated endoscopy of neurosurgical approaches in an anatomical model
1997
Endoscopy simulation is a new visualisation technique which can be used to visualise patient anatomy as seen through endoscopes. In the following, we describe the application of simulated endoscopy to neurosurgical endoscopic approaches. We assess different aspects of virtual images and their influence on the final result, as judged by clinicians. One of these aspects is the projective geometry which is used to render the 3D images. Rendering using stereographic projection leads to more realistic endoscopic views than perspective projection.
Study of CT/MRI mutual information based registration applied in brachytherapy
2016
The present work aims to include magnetic resonance imaging (MRI) in a Medical Image-based Graphical platfOrm - Brachytherapy module (AMIGOBrachy) which coupled to the Monte Carlo N-Particle (MCNP6) code allows absorbed dose calculations. Computed tomography (CT) and MRI images were registered using mutual information algorithms to improve tissue segmentation potentially leading to a more accurate treatment planning system.
Description of an improved method for Blastocystis hominis culture and axenization
1996
An improved method for Blastocystis hominis culture and axenization was developed in the present study. Stool samples were cultured in prereduced Boeck-Drbohlav NHI modified medium (with several modifications) supplemented with antibiotics (0.4% ampicillin, 0.1% streptomycin, 0.0006% amphotericin B). Axenization was performed by the combination of partial purification of B. hominis by Ficoll-metrizoic acid gradient and inoculation in fresh medium containing active antibiotics against remaining bacteria. A total of 25 strains were obtained by this procedure. The time required for axenization ranged between 3 and 5 weeks. The generation time of axenic strains ranged from 6.6 to 12.1 h (mean +…
Carcinogenic aspect of xenobiotic molecules belonging to the peroxisome proliferator family.
1999
It is known that a short-term exposure of rat, mice or incubation of hepatic cells with fibrate molecules leads to increase in peroxisome number and cell hyperplasia. Further, long-term incubation of cells (at least a year) show transformed characteristics with foci and nodules. To explain the hepatocarcinogenic effect of peroxisome proliferators in rodents we studied the effect of peroxisome proliferators on rat liver oncogenes expression. Earlier, we reported an increase in liver and kidney mRNA level of c-myc and N-myc. Since several metabolic genes are activated by PPAR (peroxisome proliferators activated receptor) through a PPRE (peroxisome proliferator response element), we suggest th…
Design, synthesis, DNA-binding and cytotoxicity evaluation of new potential combilexines
2002
Combilexines, compounds in which a DNA intercalator is linked to a minor groove binding component, interact with the DNA in a sequence specific manner to yield in most cases compounds with anticancer activity. A series of new compounds closely related to netropsin in which the two components were linked by an amide group was synthesised as potential combilexines. As some of these compounds showed cytotoxic activity in vitro, an attempt was made to rationalise their mechanism of action. The DNA binding characteristics of the carboxamides were evaluated by thermal denaturation experiments and by ethidium bromide displacement assay. Their ability to inhibit the topoisomerase I was also determi…
Binocular, Accommodative and Oculomotor Alterations In Multiple Sclerosis: A Review
2020
Multiple sclerosis (MS) is an acquired demyelinating and inflammatory neurodegenerative disease affecting the central nervous system (CNS). Clinical and subclinical ocular disturbances occur in almost all patients with MS. The objective of this narrative review was to collect and summarize the available scientific information on oculomotor, accommodative and binocular alterations that have been reported in MS. A systematic search strategy with the following descriptors was carried out: multiple sclerosis, ocular motility disorders, internuclear ophthalmoplegia, nystagmus, vergences, fixation, pupil reflex, accommodation and stereopsis. According to the search, some oculomotor alterations w…