Search results for "VST"

showing 10 items of 93 documents

Reliability and Validity of the Tilburg Frailty Indicator in 5 European Countries

2020

OBJECTIVES: To assess the internal consistency, convergent and divergent validity, and concurrent validity of the Tilburg Frailty Indicator (TFI) within community-dwelling older people in Spain, Greece, Croatia, the Netherlands, and the United Kingdom.DESIGN: Cross-sectional study.SETTING: Primary care and community settings.PARTICIPANTS: In total, 2250 community-dwelling older people (60.3% women; mean age = 79.7 years; standard deviation = 5.7).METHODS: We assessed the reliability and validity of the full TFI as well as its physical, psychological, and social domains. Baseline data of the Urban Health Centers Europe project were used. The internal consistency was assessed with the Cronbac…

GerontologyMalevalidityolder people0302 clinical medicineSelf-reported questionnaireBIOMEDICINA I ZDRAVSTVO. Javno zdravstvo i zdravstvena zaštita.Surveys and Questionnaires030212 general & internal medicineGeneral NursingReliability (statistics)media_commonNetherlandsFrailtyGreeceHealth PolicyLonelinessGeneral MedicineEuropeFeelingScale (social sciences)symbolsFemalemedicine.symptomPsychometricsmedia_common.quotation_subjectFrail ElderlyConcurrent validityfrailtySelf-reported questionnaire frailty reliability validity Europe older people03 medical and health sciencessymbols.namesakeCronbach's alphamedicineHumansGeriatric AssessmentAgedreliabilitybusiness.industryBIOMEDICINE AND HEALTHCARE. Public Health and Health Care.Reproducibility of ResultsMental healthPearson product-moment correlation coefficientUnited KingdomCross-Sectional StudiesSpainQuality of LifeGeriatrics and Gerontologybusiness030217 neurology & neurosurgery
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Primary stroke prevention worldwide:translating evidence into action

2021

Abstract: Stroke is the second leading cause of death and the third leading cause of disability worldwide and its burden is increasing rapidly in low-income and middle-income countries, many of which are unable to face the challenges it imposes. In this Health Policy paper on primary stroke prevention, we provide an overview of the current situation regarding primary prevention services, estimate the cost of stroke and stroke prevention, and identify deficiencies in existing guidelines and gaps in primary prevention. We also offer a set of pragmatic solutions for implementation of primary stroke prevention, with an emphasis on the role of governments and population-wide strategies, includin…

Global Burden of Disease03 medical and health sciences0302 clinical medicineNursingBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Neurology.Medicine030212 general & internal medicineStrokeHealth policyCause of deathEntire populationHealth professionalsbusiness.industryHealth PolicyPublic Health Environmental and Occupational HealthBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Neurologija.medicine.disease3. Good healthStrokeAction (philosophy)Stroke preventionOcclusive Cerebrovascular DiseaseLife course approachHuman medicinebusiness030217 neurology & neurosurgery
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Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread

2015

Herpesviruses form different gH/gL virion envelope glycoprotein complexes that serve as entry complexes for mediating viral cell-type tropism in vitro; their roles in vivo, however, remained speculative and can be addressed experimentally only in animal models. For murine cytomegalovirus two alternative gH/gL complexes, gH/gL/gO and gH/gL/MCK-2, have been identified. A limitation of studies on viral tropism in vivo has been the difficulty in distinguishing between infection initiation by viral entry into first-hit target cells and subsequent cell-to-cell spread within tissues. As a new strategy to dissect these two events, we used a gO-transcomplemented ΔgO mutant for providing the gH/gL/gO…

Human cytomegalovirusherpesvirusesvirusesgH/FL complexesCytomegalovirusMiceViral Envelope ProteinsMedizinische FakultätBiology (General)In Situ Hybridization0303 health sciencesMice Inbred BALB CMembrane GlycoproteinsImmunohistochemistrycytomegalovirus ; gH/FL complexes ; gO ; MCK-2 ; herpesvirusesCytomegalovirus InfectionsFemaleMCK-2BIOMEDICINA I ZDRAVSTVO. Temeljne medicinske znanosti.Research ArticleQH301-705.5Immunology-BiologyMicrobiologyVirus03 medical and health sciencesgOViral entryIn vivoVirologyGeneticsmedicineAnimalsddc:610Molecular BiologyTropism030304 developmental biology030306 microbiologyBIOMEDICINE AND HEALTHCARE. Basic Medical Sciences.RC581-607medicine.diseaseVirologyHerpesvirus glycoprotein BDisease Models AnimalViral TropismCell cultureTissue tropismParasitologyImmunologic diseases. Allergy
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Epidemiology of intra-abdominal infection and sepsis in critically ill patients: "AbSeS", a multinational observational cohort study and ESICM Trials…

2019

Pardo-Oviedo, Juan Mauricio/0000-0003-0084-3449; Lopez-Delgado, Juan Carlos/0000-0003-3324-1129; Corradi, Francesco/0000-0002-5588-2608; De Backer, Daniel/0000-0001-9841-5762; POTA, VINCENZO/0000-0001-9999-3388; Tomescu, Dana/0000-0001-9673-5754; Sabetian, Golnar/0000-0001-8764-2150; Girardis, Massimo/0000-0002-2453-0829; Brazzi, Luca/0000-0001-7059-0622; Leone, Marc/0000-0002-3097-758X; Zabolotskikh, Igor Borisovich/0000-0002-3623-2546; De Lange, Dylan/0000-0002-0191-7270; ALMEKHLAFI, GHALEB A./0000-0002-0323-7025; Elke, Gunnar/0000-0002-4948-1605; Grigoras, Ioana/0000-0001-9412-9574; Czuczwar, Miroslaw/0000-0002-9025-6717; Nora, David/0000-0002-1133-7368; Masjedi, Mansoor/0000-0001-6175-9…

Infection riskMaleBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences.Antibiotic resistanceTracte gastrointestinal - MalaltiesDefinitionsCritical Care and Intensive Care MedicineTHERAPYDEFINITIONS:Infections::Intraabdominal Infections [DISEASES]0302 clinical medicineIntensive care; Intra-abdominal infection; Mortality; Multidrug resistance; Peritonitis; Sepsis;[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesObservational studySeptic shockIntensive care; Intra-abdominal infection; Mortality; Multidrug resistance; Peritonitis; SepsisComputingMilieux_MISCELLANEOUSCritical Illness/epidemiology[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseasesBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti.Intraabdominal Infections/epidemiologyAbdominal infectionMulticenter study3. Good healthManagementClinical trialCohort[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/VirologyCohort analysisCommunity acquired infectionCohort studyHumanmedicine.medical_specialtyCarbapenem resistanceCritical IllnessPeritoneal dialysisPeritonitisVancomycin resistant enterococcusMajor clinical studyPeritonitisArticle03 medical and health sciencesAntibiotic resistance[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemIntensive careSepsisSettore MED/41 - ANESTESIOLOGIAHumansCritical care medicineHospital infectionAgedScience & TechnologyLiver failureAntibiotic therapymedicine.disease[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyEpidemiologic Studies030228 respiratory systemIntensive Care Unit; Sepsis (Diptera); Septic ShockRisk factorHuman medicineGeneral & internal medicineCongestive heart failureOriginalMultidrug resistanceCohort StudiesRisk FactorsCause of DeathEpidemiologyPrevalenceMedicine and Health SciencesAbdominal abscessSepsis/epidemiologyMiddle agedAntifungal therapy2. Zero hungerPeritonitiAntibiotic agentBiliary tract infectionIntensive care ; Intra-abdominal infection ; Mortality ; Multidrug resistance ; Peritonitis ; SepsisMiddle Aged:infecciones bacterianas y micosis::infección::infecciones intraabdominales [ENFERMEDADES]PREVALENCE:Infections::Sepsis [DISEASES]:técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos::estudios de cohortes [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]Methicillin resistant staphylococcus aureusRaonament basat en casosFemaleCritically ill patientLife Sciences & BiomedicineAntifungal agentAdult:Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies::Cohort Studies [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]Predictive value:infecciones bacterianas y micosis::infección::sepsis [ENFERMEDADES]NOSepsisIntra-abdominal infectionCritical Care MedicineInternal medicineGeneral & Internal MedicinemedicineMANAGEMENTJournal Article[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologySepticèmiaMortalitybusiness.industrySeptic shockPancreas diseaseMalnutrition030208 emergency & critical care medicineTyphlitisToxic megacolonIntensive careIntraabdominal InfectionsTherapyLate onset disorderbusiness
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4- 5 gadus vecu bērnu komunikācijas prasmju sekmēšana pirmsskolā

2020

Diplomdarba teorētiskajā daļā autore analizē teorētisko literatūru. Empīriskajā daļa ir veiktas četras praktiskās darbības: Bērnu novērojums, pedagogu intervijas,būtu veikta arī pedagoģiskā izmēģinājuma darbība, jo ārkārtas situācijas dēļ valstī, tāpēc autore izmantoja citu veida pārbaudi, eksperta analīzi, kur citi pedagogi, vērtētu izvēlētās dažādas aktivitātes, pēc iepriekš noteiktiem kritērijiem.

Komunikācijas prasmes 4 - 5 gadnieki pirmsskola attīstības raksturojumsNovērojums komunikācija pieklājības normas savstarpējā saskarsmeIntervijas pedagogi mācīšanās valoda runaPedagoģijaSociālās prasmes pirmsskolas programma saskarsme sadarbībaSkolotāja prasmju sekmēšana iedrošina bērnus vecāki piedalās
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Ar aizņēmēju saistītie riski savstarpējo aizdevumu platformu un pūļa finansēšanas nozarēs

2021

Savstarpējo aizdevumu un pūļa finansēšanas platformu nozare attīstās ļoti strauji, taču ir nepietiekami zināšanu un izpratnes par riskiem, kas saistīti ar šo nozari. Tādēļ šajā pētījumā galvenā uzmanība tiek pievērsta šo nozaru atšķirībām, kā arī kredītriska modelēšanai, pamatojoties uz vēsturisko aizdevumu datiem no savstarpējo aizdevumu un pūļa finansēšanas platformām. Vēsturiskie dati tiek izmantoti, lai analizētu un novērtētu, kuri faktori un mainīgie visvairāk ietekmē kredītsaistību neizpildi attiecībā uz aizdevumiem un aizņēmējiem. Pētījuma rezultāts tiek sasniegts, izmantojot bināro loģistiskās regresijas modeli, kas parāda, ka vairākiem faktoriem ir būtisks robežefekts uz kredīta ne…

Loģistiskā regresijaPūļa finansēšanaEkonomikaKredītriska modelēšanaSavstarpējo aizdevumu platformas
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Association between night-time surgery and occurrence of intraoperative adverse events and postoperative pulmonary complications

2019

WOS: 000458513600019

Lung DiseasesPostoperative Complications/epidemiologyMaleInternationalityIntraoperative Complicationmedicine.medical_treatmentSettore MED/41 - Anestesiologia[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractLung DiseaseCohort StudiesBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Anesteziologija i reanimatologija.0302 clinical medicine030202 anesthesiologyRisk Factorspatient safetyMedicineGeneral anaesthesiapostoperative complicationProspective Studiesintraoperative complicationsStatistics & numerical dataProspective cohort studyIncidence (epidemiology)Incidencegeneral anaesthesia intraoperative complications patient safety postoperative complications pulmonaryMiddle AgedOperative3. Good healthSurgical Procedures OperativeFemalegeneral anaesthesia ; intraoperative complications ; patient safety ; postoperative complications ; pulmonaryCohort studyHumanAdultmedicine.medical_specialtypulmonaryLung Diseases/epidemiology[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/SurgeryNO03 medical and health sciencesgeneral anaesthesia; intraoperative complications; patient safety; postoperative complications; pulmonary;Intraoperative Complications/epidemiologyAfter-Hours Carepostoperative complicationsHumansgeneral anaesthesiaMED/41 - ANESTESIOLOGIAAdverse effectAgedMechanical ventilationSurgical Proceduresbusiness.industryRisk FactorBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Anesthesiology and Reanimatology.intraoperative complicationSurgeryAfter-Hours Care/statistics & numerical datageneral anaesthesia; intraoperative complications; patient safety; postoperative complications; pulmonary; Anesthesiology and Pain MedicineClinical trialMESH: After-hours Care / statistics & numerical data; Lung diseases / epidemiology; Surgical procedures operativeProspective StudieAnesthesiology and Pain Medicine[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieCohort Studiebusiness
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Effects of alirocumab on types of myocardial infarction : insights from the ODYSSEY OUTCOMES trial

2019

Gislason, Gunnar H/0000-0002-0548-402X; Malynovsky, Yaroslav V/0000-0002-9118-1104; Bhatt, Deepak L./0000-0002-1278-6245; Nikolaev, Konstantin/0000-0003-4601-6203; Sherwood, Matthew/0000-0002-4305-5883; Chumakova, Galina A/0000-0002-2810-6531; Raffel, Owen C/0000-0001-5470-7050; Leonardi, Sergio/0000-0002-4800-6132; Tse, Hung Fat/0000-0002-9578-7808; Reshetko, Olga/0000-0003-3107-7636; Pereira, Helder/0000-0001-8656-4883; Racca, Vittorio/0000-0002-4465-3789; Podoleanu, Cristian/0000-0001-9987-2519; Ersanli, Murat/0000-0003-1847-3087; Muenzel, Thomas/0000-0001-5503-4150; Sandhu, Manjinder/0000-0003-2538-2079; Taskinen, Marja-Riitta/0000-0002-6229-3588; bastos, jose/0000-0002-9526-3123; Manak…

MaleBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences.Cardiac & Cardiovascular SystemsMyocardial InfarctionUNIVERSAL DEFINITION030204 cardiovascular system & hematologyTHERAPYDISEASEchemistry.chemical_compound0302 clinical medicineCardiac and Cardiovascular Systems030212 general & internal medicineMyocardial infarctionProspective Studies1102 Cardiorespiratory Medicine and HaematologyOxygen supplyKardiologiBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti.CHOLESTEROLMiddle AgedMI typesCardiologyLDL Cholesterol LipoproteinsFemaleCardiology and Cardiovascular MedicineLife Sciences & Biomedicinemedicine.medical_specialty610ODYSSEY OUTCOMES InvestigatorsAntibodies Monoclonal HumanizedCLASSIFICATION03 medical and health sciencesDouble-Blind MethodInternal medicinemedicineHumansddc:610Alirocumab ; MI types ; Mortality ; PreventionMortalityMETAANALYSISAlirocumabAgedScience & TechnologyTask forceCholesterolbusiness.industryEVOLOCUMABPrevention1103 Clinical SciencesCholesterol LDLmedicine.diseaseEvolocumabchemistryCardiovascular System & HematologyCardiovascular System & CardiologyHuman medicinebusinessAlirocumab
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Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study

2021

This international, prospective, cohort study enrolled 20 006 adult (≥18 years) patients from 466 hospitals in 61 countries with 15 cancer types, who had a decision for curative surgery during the COVID-19 pandemic and were followed up until the point of surgery or cessation of follow-up (Aug 31, 2020). Average national Oxford COVID-19 Stringency Index scores were calculated to define the government response to COVID-19 for each patient for the period they awaited surgery, and classified into light restrictions (index 60). The primary outcome was the non-operation rate (defined as the proportion of patients who did not undergo planned surgery). Cox proportional-hazards regression models wer…

MaleCOVID-19 COVIDSURG COVIDSURG CANCEROutcome AssessmentIMPACTSettore MED/18 - CHIRURGIA GENERALEBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Surgery.surgeryCancer surgeryNeoplasms/classificationBIOMEDICINA I ZDRAVSTVO. Javno zdravstvo i zdravstvena zaštita.Surgical oncologyNeoplasmsAcute careCOVID-19 - epidemiologyOutcome Assessment Health CareMedicine and Health Sciences80 and overGlobal healthtimingProspective StudiesUK610 Medicine & healthProspective cohort studyCOVID-19/epidemiologyCOVIDAged 80 and overBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Oncology.BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Kirurgija.Hazard ratioArticlesMiddle AgedOncologyAdult; Aged; Aged 80 and over; Communicable Disease Control; COVID-19; Female; Humans; Male; Middle Aged; Neoplasms; Outcome Assessment Health Care; Proportional Hazards Models; Prospective Studies; SARS-CoV-2; Time-to-Treatment; Withholding Treatment/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemalecancer surgeryCovid-19Life Sciences & BiomedicineMENTAL-HEALTHmental healthCohort studyHumanAdultmedicine.medical_specialtydelay3122 CancersCOVID-19 - prevention and control610 Medicine & healthCOVIDSurg CollaborativeNOTime-to-TreatmentSDG 3 - Good Health and Well-beingLockdownmedicineHumanscancer1112 Oncology and CarcinogenesisOncology & CarcinogenesisElective surgeryLS7_4Proportional Hazards ModelsAgedScience & Technologybusiness.industrySARS-CoV-2Public healthGeneral surgeryBIOMEDICINE AND HEALTHCARE. Public Health and Health Care.COVID-193126 Surgery anesthesiology intensive care radiologyHealth CareCommunicable Disease Control/legislation & jurisprudenceProspective StudieWithholding TreatmentCOVID-19; delay; SARS-CoV-2; surgery; timing; cancer surgery;COVID-19 ; lockdowns ; cancer surgeryCommunicable Disease ControlBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Onkologija.Proportional Hazards ModelNeoplasmbusiness
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Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease : results from the EUROASPIRE IV …

2018

Background: This study aims to assess the cost-effectiveness of optimized guideline adherence in patients with a history of coronary heart disease. Methods: An individual-based decision tree model was developed using the SMART risk score tool which estimates the 10-year risk for recurrent vascular events in patients with manifest cardiovascular disease (CVD). Analyses were based on the EUROASPIRE IV survey. Outcomes were expressed as an incremental cost-effectiveness ratio (ICER). Results: Data from 4663 patients from 13 European countries were included in the analyses. The mean estimated 10-year risk for a recurrent vascular event decreased from 20.13% to 18.61% after optimized guideline a…

MaleCardiac & Cardiovascular SystemsCost effectivenessmedicine.medical_treatmentCost-Benefit AnalysisCoronary DiseaseDisease030204 cardiovascular system & hematology0302 clinical medicineOlder patientsMedicine030212 general & internal medicineguidelinesEUROASPIRE1102 Cardiorespiratory Medicine and Haematologyhealth care economics and organizationsBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Interna medicina.Framingham Risk ScoreSecondary preventionASSOCIATIONMiddle AgedhumanitiesCoronary heart diseaseEuropeDENSITY-LIPOPROTEIN CHOLESTEROLPractice Guidelines as TopicTRIALFemaleGuideline AdherenceCardiology and Cardiovascular MedicineLife Sciences & Biomedicinesecondary prevention ; guidelines ; cost-effectiveness ; coronary heart disease ; EUROASPIREsecondary preventionmedicine.drugINTERVENTIONSmedicine.medical_specialtyEZETIMIBEGuidelinesEVENTS03 medical and health sciencesEzetimibeInternal medicineHumansIn patientcoronary heart diseaseBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Internal Medicine.cost-effectivenessMETAANALYSISAgedScience & Technologybusiness.industryDecision TreesSMOKING-CESSATIONCoronary heart diseaseTHRESHOLDSCardiovascular System & HematologyCardiovascular System & CardiologySmoking cessationCost-effectivenessbusinessSTATIN TREATMENT
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