Search results for "Valuation"

Cell Lines: A Tool for In Vitro Drug Metabolism Studies

2008

Primary cultured hepatocytes are a valuable in vitro model for drug metabolism studies. However, their widespread use is greatly hindered by the scarcity of suitable human liver samples. Moreover, the well-known in vitro phenotypic instability of hepatocytes, the irregular availability of fresh human liver for cell harvesting purposes, and the high batch-to-batch functional variability of hepatocyte preparations obtained from different human liver donors, seriously complicate their use in routine testing. To overcome these limitations, different cell line models have been proposed for drug metabolism screening. Human liver-derived cell lines would be ideal models for this purpose given thei…

Le varietà di grano duro per le semine 2021. Sicilia

2021

Anche nel 2020-21, pur nelle difficili circostanze determinate per il secondo anno consecutivo dalla pandemia da Covid-19, sono state condotte in Sicilia le prove della Rete nazionale di confronto varietale di frumento duro. I campi sperimentali sono stati allestiti in 5 ambienti siciliani. La sperimentazione ha riguardato 30 varieta’, di cui ben 9 al primo anno di valutazione. I risultati produttivi riscontrati nelle diverse localita’ appaiono molto differenti e fortemente influenzati dall’andamento meteorologico verificatosi nelle diverse zone dell’Isola. At 2020-21, despite the difficult circumstances determined for the second consecutive year by the Covid-19 pandemic, the tests of the n…

Le varietà di grano duro per le semine 2020: Sicilia

2020

Nonostante le difficoltà operative dovute alla pandemia da Covid-19, anche nel corso del 2019-20 sono state condotte in Sicilia le prove di confronto varietale di frumento duro, allestite in 5 località della Sicilia: Libertinia (Catania), Catania, S. Stefano Quisquina (Agrigento), Caltagirone (Catania) e Ciminna (Palermo). La sperimentazione ha riguardato 30 varietà, di cui 5 al primo anno di valutazione, 9 cultivar al secondo anno di prova e 16 genotipi testati da oltre due anni. La resa media dell’areale siciliano è stata pari a 6,11 t/ha e i risultati produttivi registrati nei diversi ambienti di prova appaiono sensibilmente influenzati dall’andamento termo-pluviometrico. Despite the dif…

Sealing ability of five different retrograde filling materials.

1996

The sealing ability of Amalgam, Harvard-Cement, Diaket, gold-leaf, and Ketac-Endo as retrofilling materials was investigated. Paper cones were fixed with Harvard-Cement in the instrumented roots of 100 extracted human incisors. Apicectomy was performed and a 2-mm-deep retrograde cavity was prepared. Teeth were assigned to five groups (n = 20); each group received a different filling material. Surfaces of the roots were isolated with nail polish. Teeth, were stored in 1% methylene blue dye for 72 h. Roots were sectioned, and the depth of dye penetration was evaluated through a stereomicroscope. Retrofills with Ketac-Endo showed significantly less leakage compared with amalgam. There was no s…

Both Short- and Long-Acting D-1/D-2 Dopamine Agonists Induce Less Dyskinesia than l-DOPA in the MPTP-Lesioned Common Marmoset (Callithrix jacchus)

2002

Abstract The current concept of dyskinesia is that pulsatile stimulation of D-1 or D-2 receptors by l -DOPA or short-acting dopamine agonists is more likely to induce dyskinesia compared to long-acting drugs producing more continuous receptor stimulation. We now investigate the ability of two mixed D-1/D-2 agonists, namely pergolide (long-acting) and apomorphine (short-acting), to induce dyskinesia in drug-naive MPTP-lesioned primates, compared to l -DOPA. Adult common marmosets ( Callithrix jacchus ) were lesioned with MPTP (2 mg/kg/day sc for 5 days) and subsequently treated with equieffective antiparkinsonian doses of l -DOPA, apomorphine, or pergolide for 28 days. l -DOPA, apomorphine, …

Carga global, regional y nacional de neurológicas. Desórdenes, 1990-2016: un análisis sistemático para el Global Estudio de la carga de enfermedad 20…

2019

Publisher´s version (útgefin grein).

L’auto-évaluation au service du développement professionnel des personnels de direction stagiaires

2022

Comment l'évaluation des politiques publiques contribue t'elle à la vie démocratique ?

2017

En ligne sur http://www.cnesco.fr/wp-content/uploads/2017/09/Contributions_Evaluation_et_democratie.pdf; Le Conseil national d'évaluation du système scolaire (Cnesco) engage, en partenariat avec le Conseil économique, social et environnemental (CESE), France Stratégie et le laboratoire interdisciplinaire d'évaluation des politiques publiques (LIEPP -Sciences Po) une réflexion sur le lien entre vie démocratique et évaluation des politiques publiques. Dans ce cadre, des acteurs et des usagers de l'évaluation des politiques publiques ont été sollicités afin de fournir une contribution sur la thématique suivante : " Comment l'évaluation des politiques publiques contribue-t-elle à la vie démocra…

La démocratisation de l'enseignement en France : comment l'évaluer, à quoi l'attribuer ?

2000

International audience

Analyse de la réussite en première année universitaire : effets des facteurs sociaux, scolaires et cognitifs

2012

Documents de travail de l'IREDU, n°2012-2; L'objectif principal de cette recherche est de mieux comprendre l'articulation entre les différents facteurs qui agissent sur la réussite des étudiants au terme de la première année à l'Université. Une originalité de la démarche est d'intégrer aux modèles explicatifs de la réussite, des indicateurs spécifiques des compétences des étudiants à leur entrée à l'Université : mesures des performances académiques (niveau en compréhension de l'écrit) et des capacités cognitives. Les analyses mettent en évidence le poids très fort du passé scolaire (retard scolaire, série et mention du bac), le niveau en compréhension de l'écrit et les capacités cognitives …