Search results for "Variant"

The role of the $\Delta(1232)$-resonance in covariant baryon chiral perturbation theory

2013

We stress, on theoretical and phenomenological grounds, the importance of the $\Delta(1232)$-resonance in a chiral effective field theory approach applied to the study of $\pi N$ scattering. We show how its inclusion as a dynamical degree of freedom allow us to obtain reliably valuable information from $\pi N$ scattering data.

Chiral coupled channel dynamics of theΛ(1520)and theK−p→π0π0Λreaction

2005

We study the $\ensuremath{\Lambda}(1520){D}_{03}$ in a chiral coupled channel approach. This resonance appears to be dynamically generated from the interaction of the decuplet of baryons and the octet of mesons in s wave, and its treatment is improved here with the phenomenological inclusion of the $\overline{K}N$ and $\ensuremath{\pi}\ensuremath{\Sigma}$ channels in d wave. Since the most important building block in $\ensuremath{\Lambda}(1520)$ is the $\ensuremath{\pi}{\ensuremath{\Sigma}}^{*}(1385){P}_{13}$ channel, we study the ${K}^{\ensuremath{-}}p\ensuremath{\rightarrow}\ensuremath{\pi}{\ensuremath{\Sigma}}^{*}(1385)({\ensuremath{\pi}}^{0}\ensuremath{\Lambda})$ reaction in the region …

Weak decay ofΛc+for the study ofΛ(1405)andΛ(1670)

2015

We study the ${\mathrm{\ensuremath{\Lambda}}}_{c}$ decay process to ${\ensuremath{\pi}}^{+}$ and the meson-baryon final state for the analysis of $\mathrm{\ensuremath{\Lambda}}$ resonances. Considering the Cabibbo-Kobayashi-Maskawa matrix, color suppression, diquark correlation, and the kinematical condition, we show that the final meson-baryon state should be in a pure $I=0$ combination, when the meson-baryon invariant mass is small. Because the $I=1$ contamination usually makes it difficult to analyze $\mathrm{\ensuremath{\Lambda}}$ resonances directly from experiments, the ${\mathrm{\ensuremath{\Lambda}}}_{c}$ decay is an ideal process to study $\mathrm{\ensuremath{\Lambda}}$ resonances.…

No association of alcohol dependence with a NMDA-receptor 2B gene variant

2003

Intronic Variant in CNTNAP2 Gene in a Boy With Remarkable Conduct Disorder, Minor Facial Features, Mild Intellectual Disability, and Seizures

2020

Introduction: Mutations in the contactin-associated protein-like 2 (CNTNAP2) gene (MIM#604569) encoding for CASPR2, a cell adhesion protein of the neurexin family, are known to be associated with autism, intellectual disability, and other neuropsychiatric disorders. A set of intronic deletions of CNTNAP2 gene has also been suggested to have a causative role in individuals with a wide phenotypic spectrum, including Pitt-Hopkins syndrome, cortical dysplasia–focal epilepsy syndrome, Tourette syndrome, language dysfunction, and abnormal behavioral manifestations. Case presentation: A 10-years-old boy was referred to the hospital with mild intellectual disability and language impairment. Moreove…

Prevalence of Anatomical Variants and Coronary Anomalies in 202 Consecutive Patients by 64-slice CT Coronary Angiography

2006

Anatomical Variants of Coronary Artery Tree by 64-slice CT Coronary Angiography with Conventional Coronary Angiography Correlation

2005

Oligodendroglioma cells synthesize the differentiation-specific linker histone H1˚ and release it into the extracellular environment through shed ves…

2013

Chromatin remodelling can be involved in some of the epigenetic modifications found in tumor cells. One of the mechanisms at the basis of chromatin dynamics is likely to be synthesis and incorporation of replacement histone variants, such as the H1° linker histone. Regulation of the expression of this protein can thus be critical in tumorigenesis. In developing brain, H1° expression is mainly regulated at the post-transcriptional level and RNA-binding proteins (RBPs) are involved. In the past, attention mainly focused on the whole brain or isolated neurons and little information is available on H1° expression in other brain cells. Even less is known relating to tumor glial cells. In this st…

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

2014

Introduction More than 70 common alleles are known to be involved in breast cancer (BC) susceptibility, and several exhibit significant heterogeneity in their associations with different BC subtypes. Although there are differences in the association patterns between BRCA1 and BRCA2 mutation carriers and the general population for several loci, no study has comprehensively evaluated the associations of all known BC susceptibility alleles with risk of BC subtypes in BRCA1 and BRCA2 carriers. Methods We used data from 15,252 BRCA1 and 8,211 BRCA2 carriers to analyze the associations between approximately 200,000 genetic variants on the iCOGS array and risk of BC subtypes defined by estrogen re…

Geographical distribution and oncogenic risk association of human papillomavirus type 58 E6 and E7 sequence variations.

2013

Human papillomavirus (HPV) 58 accounts for a notable proportion of cervical cancers in East Asia and parts of Latin America, but it is uncommon elsewhere. The reason for such ethnogeographical predilection is unknown. In our study, nucleotide sequences of E6 and E7 genes of 401 HPV58 isolates collected from 15 countries/cities across four continents were examined. Phylogenetic relationship, geographical distribution and risk association of nucleotide sequence variations were analyzed. We found that the E6 genes of HPV58 variants were more conserved than E7. Thus, E6 is a more appropriate target for type-specific detection, whereas E7 is more appropriate for strain differentiation. The frequ…