Search results for "Variations"
showing 10 items of 129 documents
Copy number variation and missense mutations of the agouti signaling protein (ASIP) gene in goat breeds with different coat colors.
2009
In goats, classical genetic studies reported a large number of alleles at the Agouti locus with effects on coat color and pattern distribution. From these early studies, the dominant A(Wt) (white/tan) allele was suggested to cause the white color of the Saanen breed. Here, we sequenced the coding region of the goat ASIP gene in 6 goat breeds (Girgentana, Maltese, Derivata di Siria, Murciano-Granadina, Camosciata delle Alpi, and Saanen), with different coat colors and patterns. Five single nucleotide polymorphisms (SNPs) were identified, 3 of which caused missense mutations in conserved positions of the cysteine-rich carboxy-terminal domain of the protein (p.Ala96Gly, p.Cys126Gly, and p.Val1…
Effect of hypoosmotic stress by low salinity acclimation of Mediterranean mussels Mytilus galloprovincialis on biological parameters used for polluti…
2008
In the present study, we investigated the progressive acclimation of the mussel Mytilus galloprovincialis to different reduced seawater (SW) salinities and its effect on several biochemical markers and biotests. Mussels were purchased from a local mariculture facility during summer (SW temperature 27 degrees C, salinity 37.5 psu) and winter (13 degrees C, 37 psu) seasons, and transferred to the laboratory for acclimation to reduced SW salinities (37, 28, 18.5 and 11 psu). At the beginning and at the end of acclimation processes tests of mussel survival in air were provided. After 14 days of acclimation the DNA integrity, p38-MAPK activation, metallothionein induction, oxygen consumption rat…
Functional ecology for evaluating and predicting the aptitude of permanent grassland to provide services
2013
National audience; Applying the principles of functional ecology helps better predict the services which can be provided by permanent grassland. Farming practices and environmental characteristics influence the functional composition of grassland. Functional plant types have a generic effect on forage services which can be assessed. 13 types of grassland composed of distinct functional types were defined based on 1,283 sample grassland fields located on 8 sites. This approach was validated by checking 8 Ellenberg indicator values (used to evaluate environmental characteristics and farming practices) against climatic data and descriptive data for farming practices. The interest of a function…
Approximation of Elliptic Hemivariational Inequalities
1999
From the previous chapter we know that there exist many important problems in mechanics in which constitutive laws are expressed by means of nonmonotone, possibly multivalued relations (nonmonotone multivalued stress-strain or reaction-displacement relations,e.g). The resulting mathematical model leads to an inclusion type problem involving multivalued nonmonotone mappings or to a substationary type problem for a nonsmooth, nonconvex superpotential expressed in terms of calculus of variation. It is the aim of this chapter to give a detailed study of a discretization of such a type of problems including the convergence analysis. Here we follow closely Miettinen and Haslinger, 1995, Miettinen…
Are
2017
Objectives To investigate the association between IL18RAP and body mass index (BMI) and obesity and to verify the effect of a polymorphism in the microRNA136 (MIR136) IL18RAP binding region. Design We analysed samples from two Spanish cross-sectional studies, VALCAR (Spanish Mediterranean coast) and Hortega (Spanish centre). These studies aimed at analysing cardiovascular risk and development of cardiovascular disease in the general population. Both populations correspond to regions with different characteristics. Setting Five IL18RAP single nucleotide polymorphisms were selected using the SYSNPs web tool and analysed by oligonucleotide ligation assay (SNPlex). For the MIR136 functional stu…
On Variational Measures Related to Some Bases
2000
Abstract We extend, to a certain class of differentiation bases, some results on the variational measure and the δ-variation obtained earlier for the full interval basis. In particular the theorem stating that the variational measure generated by an interval function is σ-finite whenever it is absolutely continuous with respect to the Lebesgue measure is extended to any Busemann–Feller basis.
On Computational Properties of a Posteriori Error Estimates Based upon the Method of Duality Error Majorants
2004
In the present paper, we analyze computational properties of the functional type a posteriori error estimates that have been derived for elliptic type boundary-value problems by duality theory in calculus of variations. We are concerned with the ability of this type of a posteriori estimates to provide accurate upper bounds of global errors and properly indicate the distribution of local ones. These questions were analyzed on a series of boundary-value problems for linear elliptic operators of 2nd and 4th order. The theoretical results are confirmed by numerical tests in which the duality error majorant for the classical diffusion problem is compared with the standard error indicator used i…
SNPs array karyotyping reveals a novel recurrent 20p13 amplification in primary myelofibrosis.
2011
The molecular pathogenesis of primary mielofibrosis (PMF) is still largely unknown. Recently, single-nucleotide polymorphism arrays (SNP-A) allowed for genome-wide profiling of copy-number alterations and acquired uniparental disomy (aUPD) at high-resolution. In this study we analyzed 20 PMF patients using the Genome-Wide Human SNP Array 6.0 in order to identify novel recurrent genomic abnormalities. We observed a complex karyotype in all cases, detecting all the previously reported lesions (del(5q), del(20q), del(13q), +8, aUPD at 9p24 and abnormalities on chromosome 1). In addition, we identified several novel cryptic lesions. In particular, we found a recurrent alteration involving cytob…
Historical Part—Calculus of Variations
2018
The calculus of variations is an old mathematical discipline and historically finds its origins in the introduction of the brachistochrone problem at the end of the 17th century by Johann Bernoulli to challenge his contemporaries to solve it. Here, we briefly introduce the reader to the main results.
Determinants of the interannual relationships between remote sensed photosynthetic activity and rainfall in tropical Africa
2007
International audience; The response of photosynthetic activity to interannual rainfall variations in Africa South of the Sahara is examined using 20 years (1981-2000) of Normalised Difference Vegetation Index (NDVI) AVHRR data. Linear correlations and regressions were computed between annual NDVI and annual rainfall at a 0.5° latitude/longitude resolution, based on two gridded precipitation datasets (Climate Prediction Center Merged Analysis of Precipitation [CMAP] and Climatic Research Unit [CRU]). The spatial patterns were then examined to detect how they relate to the mean annual rainfall amounts, land-cover types as from the Global Land Cover 2000 data set, soil properties and soil typ…