Search results for "Vascular"
showing 10 items of 10708 documents
Role of Biological Sex in the Cardiovascular-Gut Microbiome Axis
2022
There has been a recent, unprecedented interest in the role of gut microbiota in host health and disease. Technological advances have dramatically expanded our knowledge of the gut microbiome. Increasing evidence has indicated a strong link between gut microbiota and the development of cardiovascular diseases (CVD). In the present article, we discuss the contribution of gut microbiota in the development and progression of CVD. We further discuss how the gut microbiome may differ between the sexes and how it may be influenced by sex hormones. We put forward that regulation of microbial composition and function by sex might lead to sex-biased disease susceptibility, thereby offering a mechani…
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry
2009
We conducted meta-analyses of genome-wide association studies (GWAS) for atrial fibrillation (AF) in participants from five community-based cohorts. Meta-analyses of 896 prevalent (15,768 referents) and 2,517 incident (21,337 referents) AF cases identified a novel locus for AF (ZFHX3, rs2106261, risk ratio [RR]=1.19; P=2.3×10−7), an association that was replicated in the German AF Network (odds ratio=1.44; P=1.6×10−11). Combining the discovery and replication results, rs2106261 was significantly associated with AF (RR=1.25; P=1.8×10−15).
Modificaciones del automatismo, conducción, refractariedad miocárdicas y del patrón fibrilatorio ventricular producidas por el ejercicio físico cróni…
2011
El objetivo de este trabajo es investigar el papel de las neuronas parasimpáticas postganglionares en los cambios adaptativos producidos por el entrenamiento físico sobre el automatismo, la conducción y la refractariedad miocárdicas. Se utilizaron 41 conejos de raza New Zealand White que fueron divididos en 3 grupos: un grupo de animales control (n=14), un grupo de animales falsos operados (n=13) y un grupo de animals entrenados (n=14). Estos últimos fueron sometidos a un protocolo de entrenamiento en cinta rodante de 6 semanas de duración. El estudio electrofisiológico se realizó en corazón aislado y, por tanto, no sometido a influencias nerviosas extrínsecas ni humorales. Las propiedades …
Septic skin lesions: An uncommon manifestation of peripheral prosthetic vascular graft infection
2014
Peripheral prosthetic vascular graft infection following lower limb surgical revascularization is a relatively rare but serious condition. A case of early infection and occlusion of a above-knee femoro-popliteal artery prosthetic bypass is here reported. It was accompanied by acute lower limb ischemia, fever and distally by embolic septic skin lesions.
Who needs to care about small, dense low density lipoproteins?
2007
Background: Increasing evidence suggest that the ‘quality’ rather than only the ‘quantity’ of low-density lipoprotein (LDL) exerts a great influence on the cardiovascular risk. Small, dense LDL seem to be an important predictor of cardiovascular events and progression of coronary artery disease (CAD) and their predominance has been accepted as an emerging cardiovascular risk factor by the National Cholesterol Education Program Adult Treatment Panel III. Discussion: Some studies showed in past years that small, dense LDL are usually elevated in patients at very high cardiovascular risk, such as those with CAD and type 2 diabetes. More recently elevated levels of these particles have been fou…
Nitrogen-fixing cushion Astragalus siculus modulates soil fertility, microclimate, plant facilitation, bacterial and fungal microbiota along an eleva…
2023
Question: Cushion-forming vascular plants are adapted to alpine environments and act as ecosystem engineers by moderating microclimate and creating a fertility island under their canopy. Most of the available studies on cushion ecology have been devoted to plant facilitation, but none used a holistic approach that considers the response of co-existing plant species with other key ecosystem players. Here, we quantified the biogenic effect and facilitation capacity of Astragalus siculus, a spiny nitrogen-fixing cushion plant, and test the hypothesis that the facilitation effect would increase with elevation as stress gradient.Location: Mount Etna, the highest active volcano in the Mediterrane…
Resting electrocardiogram and blood pressure in young athletes and nonathletes : A 4-year follow-up
2022
A follow-up data on electrocardiogram (ECG) and blood pressure (BP) changes in adolescent athletes are scarce. We compared ECG and BP between adolescent athletes and non-athletes in a 4-year follow-up. A total of 154 youth sports clubs (SC) in Finland and 100 secondary schools for comparison data participated in this observational follow-up study. Those who maintained or adopted SC participation are referred to as “Always athletes” (n=137), those who never participated in SC as “Never athletes” (n=108) and those who dropped out of SC during the follow-up as “Changers” (n=116). The mean age of the participants was 15.5 (0.6) years in all study groups at baseline. Resting ECG including heart …
Percutaneous Recanalization of Chronic Total Occlusions : 2019 Consensus Document from the EuroCTO Club
2019
Since its inception in December 2006, the EuroCTO Club has strived to provide the framework for state-of-the-art chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in Europe and nearby regions. Among its initiatives, the EuroCTO Club has published a set of recommendations regarding the technical aspects of CTO PCI, whose last edition dates to 2012. The EuroCTO Club consensus document discusses CTO PCI clinical indications, techniques and equipment use, as well as the qualifications of operators/centres. Given the considerable amount of progress made by this subspecialty in recent years, there is a need for an updated document that includes data from recent clinical trial…
Wewnątrznaczyniowe dwuetapowe leczenie tętniaków aorty brzusznej z użyciem Heli-FX EndoAnchor System
2019
Wstęp: Wyniki leczenia tętniaków aorty brzusznej mimo wprowadzenia nowych technik wewnątrznaczyniowych nadal nie zawsze są zadowalające. Szczególnie trudną grupą pacjentów są osoby z krótką oraz stożkową szyją. W tej grupie chorych często występuje w okresie pooperacyjnym przeciek typu I. Jedną z metod mających temu powikłaniu zapobiec jest zastosowanie wkrętów wewnątrznaczyniowych Heli-FX. Ma to zwiększyć przyleganie systemu stentgraftu do ściany aorty brzusznej oraz zapobiec jego ewentualnej migracji. Materiał i metody: Autorzy niniejszego artykułu proponują zastosowanie leczenia dwuetapowego. Pierwszy etap stanowiła implantacja przedłużki aortalnej tuż poniżej odejścia tętnic nerkowych i…