Search results for "Verdi"

showing 10 items of 139 documents

Optogenetic Control of Bacterial Expression by Red Light

2022

In optogenetics, as in nature, sensory photoreceptors serve to control cellular processes by light. Bacteriophytochrome (BphP) photoreceptors sense red and far-red light via a biliverdin chromophore and, in response, cycle between the spectroscopically, structurally, and functionally distinct Pr and Pfr states. BphPs commonly belong to two-component systems that control the phosphorylation of cognate response regulators and downstream gene expression through histidine kinase modules. We recently demonstrated that the paradigm BphP from Deinococcus radiodurans exclusively acts as a phosphatase but that its photosensory module can control the histidine kinase activity of homologous receptors.…

HistoryfytokromitSIGNALING MECHANISMHistidine KinaseLightPolymers and PlasticsBiomedical EngineeringHISTIDINE KINASESfotobiologiasensory photoreceptorBiochemistry Genetics and Molecular Biology (miscellaneous)Industrial and Manufacturing EngineeringbakteeritOPTICAL CONTROLgeeniekspressioBusiness and International ManagementoptogeneticsHEME OXYGENASEGENE-EXPRESSIONphytochromeoptogenetiikkaPHOTORECEPTORSBacteriaBiliverdineREARRANGEMENTSBACTERIOPHYTOCHROMESGeneral MedicinePhosphoric Monoester HydrolasesOptogeneticsreseptorit (biokemia)two-component systemESCHERICHIA-COLIgene expression1182 Biochemistry cell and molecular biology3111 BiomedicinePhytochromevalosignal transductionSSRN Electronic Journal
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Evoluzione della popolazione blastomicetica durante la produzione di olive da tavola di differenti cultivar siciliane monitorata attraverso l’analisi…

2008

La popolazione blastomicetica di olive verdi da tavola, prodotte a partire da 4 diverse cultivar siciliane (Brandofino, Castriciana, Nocellara del Belice, Passulunara) e da una spagnola (Manzanilla), è stata monitorata durante l’intero processo di fermentazione. La tecnologia produttiva poteva definirsi di tipo semi-industriale, giacché il ruolo della microflora lattica era parzialmente sostituito dall’aggiunta di acido lattico e la fermentazione naturale avveniva in salamoia all’8% di NaCl. La popolazione di lieviti all’avvio del processo fermentativo è risultata, indipendentemente dalla cultivar di appartenenza, nell’ordine di 2.0 log UFC g-1. Viceversa nel prodotto al consumo le conte ha…

ITS-RFLPOlive da tavolaOlive verdi da tavola SicilianeIdentificazioneSiciliaPichia kluyveriLievitiComunità blastomiceticaSettore AGR/16 - Microbiologia Agraria
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A systematic analysis of duplicate records in Scopus

2015

In recent years, the Web of Science Core Collection and Scopus databases have become primary sources for conducting studies that evaluate scientific investigations. Such studies require that duplicate records be excluded to avoid errors of overrepresentation. In this line, we identify duplicate records in Scopus and examine their origins. Identifying journals with duplicate records in Scopus, selecting and downloading bibliographic journal records, and identifying and analyzing the duplicate records is the methodology adopted. Duplicate records are found when articles published in a journal are incorrectly mapped by Scopus to this journal and to a different journal from the same publisher a…

Information retrievalComputer scienceMEDLINEScopusLibrary and Information SciencesComputer Science ApplicationsBibliographic recordDuplicate recordsIndexing errorsScopus databaseBibliographic control guidelinesGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)Bibliometric indicators overdimensionalized
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ARCHITETTURA, CUSTODE DELLA NATURA : il progetto di suolo nella trasformazione delle autostrade urbane, 1962-2018

2023

Un inarrestabile cambiamento nel paradigma con cui l’uomo concepisce la propria specie rispetto ai suoi modi di costruire è alla base dell’attrattiva per l’incorporazione del vegetale nell’Architettura. Lo statuto euristico di maggiore capacità di tale nuovo corso è la sostituzione progressiva dell’Ambiente alla Natura fra i motori della Composizione. Su questo sfondo, l’articolo indaga l’ibridazione del vegetale e del costruito nella trasformazione contemporanea delle grandi autostrade urbane, attraverso un approccio diacronico e comparativo, in riferimento a una ricerca internazionale di cui estende l’ipotesi principale. A tal fine, ricostruisce il telaio ermeneutico di riferimento discut…

Infrastructura Naturans Urban freeways regeneration Paving design Interspecism Palermo’s ring roadSettore ICAR/14 - Composizione Architettonica E Urbanainfrastrutture verdi rigenerazione progetto del suolo autostrade urbane circonvallazione
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Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1—evidence for direct and …

2009

Heme oxygenase-1 (HO-1) is highly protective in various pathophysiological states such as cardiovascular and neurodegenerative diseases. HO-1-derived bilirubin is an efficient scavenger of reactive oxygen and nitrogen species (RONS). It remains to determine whether conversion of biliverdin to bilirubin is an essential step for HO-1-conferred protection of endothelial cells. RONS scavenging activities of biliverdin versus bilirubin were assessed by different RONS generating systems and detection techniques. We also silenced the biliverdin reductase (BVR) or HO-1 gene in cultured primary human endothelial cells (HUVECs) and measured the effect on RONS formation upon stimulation with lipopolys…

LipopolysaccharidesOxidoreductases Acting on CH-CH Group DonorsUmbilical VeinsXanthine OxidaseNeutrophilsBilirubinNitrosationModels BiologicalAntioxidantschemistry.chemical_compoundPeroxynitrous AcidLeukocytespolycyclic compoundsHumansGene SilencingMolecular BiologyHemeReactive nitrogen speciesRespiratory BurstBiliverdinAngiotensin IIBiliverdineBiliverdin reductaseEndothelial CellsBilirubinFree Radical ScavengersAngiotensin IIMitochondriaEndothelial stem cellHeme oxygenasechemistryBiochemistryCytoprotectionGene Knockdown TechniquesTyrosineReactive Oxygen SpeciesCardiology and Cardiovascular MedicineHeme Oxygenase-1Journal of Molecular and Cellular Cardiology
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SISTEMI VERDI COME CULTURA RIGENERATIVA: STRUMENTI E TECNOLOGIE

2021

The study analyzes and proposes in the historical and in the area immediately to it adjacent, the "values-nature" of the buildings through the creation of gardens wall and vertical gardens in the elevatiloy of non-monumental buildings. The study deepens in particular the specificity of the garden roof and the garden vertical, recognizing benefits and critical issues that distinguish these green systems for construction. It also deepens the concept of resilience in close relationship sustainability and regenerative design applied to the built environment. The theme of regenerative design is studied and promoted as an adaptive strategy at the design stage; it requires you to leave nature stre…

Lo studio analizza e propone nel centro storico e nell’area immediatamente ad esso adiacente la ”valori-naturazione” degli edifici attraverso la creazione di giardini pensili e di giardini verticali nei prospetti degli immobili non monumentali. Lo studio approfondisce in particolare le specificità del tetto giardino e del giardino verticale riconoscendo benefici e criticità che contraddistinguono questi sistemi verdi per l’edilizia. Si approfondisce inoltre il concetto di resilienza in stretta relazione alla sostenibilità e al regenerative design applicato all’ambiente costruito. Il tema del regenerative design viene studiato e promosso come strategia adattiva in fase di progettazioneesso richiede di lasciare che la natura rafforzi le sue capacità di autoguarigione e la sua integrità mediante l’uso di metodologie rigenerative integrate. Lo studio intende proporre una base su cui poter fondare ulteriori sviluppi scientifici sui sistemi di inverdimento esistenti o su brevetti in fase di sviluppo applicabili ai centri storici del territorio siciliano. Si prevede la redazione di un libretto divulgativo per gli abitanti volto alla disseminazione di una cultura del verde tecnologico ancora poco presente nei centri siciliani. Per quanto concerne le modalità attuative del progetto di ricerca sono state individuate: sia azioni orientate alla sensibilizzazione dei cittadini di Alcamo e dei residenti nella provincia sia l’individuazione di possibili forme di incentivazione per la mobilitazione di risorse private. Tale studio si inserisce nell’ambito di un filone di ricerca in itinere sui sistemi tecnologici di inverdimento per la costruzione di “Città parco” e di “Green hill” le cui linee guida e modalità attuative sono già state individuate dall’autrice per diversi comuni siciliani.Settore ICAR/12 - Tecnologia Dell'Architettura
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The impact of overdiagnosis on thyroid cancer epidemic in Italy,1998-2012

2018

Aims: In Italy, incidence rates of thyroid cancer (TC) are among the highest world- wide with substantial intracountry heterogeneity. The aim of the study was to examine time trends of TC incidence in Italy and to estimate the proportion of TC cases potentially attribut- able to overdiagnosis. Methods: Data on TC cases reported to Italian cancer registries during 1998e2012 aged <85 years were included. Age-standardised incidence rates (ASR) were computed by sex, period, and histology. TC overdiagnosis was estimated by sex, period, age, and Italian region. Results: In Italy between 1998e2002 and 2008e2012, TC ASR increased of 74% in women (from 16.2 to 28.2/100,000) and of 90% in men (fro…

MaleCancer ResearchMedical OveruseSettore MED/42 - Igiene Generale E Applicata0302 clinical medicineRegistriesYoung adultOverdiagnosisChildThyroid cancerAged 80 and overeducation.field_of_studyIncidence (epidemiology)IncidenceThyroidTime trendsMiddle Agedmedicine.anatomical_structureOncologyItaly030220 oncology & carcinogenesisChild PreschoolFemalemedicine.symptomAdultIncidence; Italy; Mortality; Overdiagnosis; Thyroid cancer; Time trends; Oncology; Cancer ResearchOverdiagnosisAdolescentPopulationSocio-culturale030209 endocrinology & metabolismAsymptomaticThyroid cancer03 medical and health sciencesYoung AdultmedicineHumansThyroid NeoplasmsMortalityeducationEpidemicsAgedbusiness.industryInfant NewbornCancerInfantmedicine.diseaseOverdiagnosibusinessDemography
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Increasing incidence and survival of paediatric and adolescent thyroid cancer in Cyprus 1998–2017: A population-based study from the Cyprus Pediatric…

2021

Paediatric and adolescent thyroid cancer incidence rates are increasing in many countries. We determined incidence rates, temporal trends and survival from thyroid cancer diagnosed in childhood and adolescence in Cyprus during 1998-2017.Patients aged 0-19 years, diagnosed with thyroid cancer in the Pediatric Oncology Registry of Cyprus were included. Crude incidence rates, age standardized rates, time trends and overall survival were analysed. Annual rates and temporal trends were calculated using Microsoft Excel 2016 and Joinpoint regression analysis.Eighty-one cases (76.5 % female, 23.5 % male) were identified. The crude rates (per 100,000 persons) were for both sexes 2.00 (95 % CI 1.61, …

MaleCancer ResearchPediatricsmedicine.medical_specialtyAdolescentEpidemiologyPopulationThyroid carcinomamedicinePediatric oncologyHumansRegistriesThyroid NeoplasmsOverdiagnosisChildeducationThyroid cancereducation.field_of_studyChildhood Cancer Registrybusiness.industryIncidenceIncidence (epidemiology)medicine.diseaseOncologyThyroid Cancer PapillaryCyprusFemaleStandardized ratebusinessCancer Epidemiology
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Italian Deprivation Index and Dental Caries in 12-Year-Old Children: A Multilevel Bayesian Analysis

2014

Evidence from the literature has shown that people with a lower socioeconomic status enjoy less good health than people with a higher socioeconomic status. The Italian deprivation index (DI) was used with the aim to evaluate the association between the DMFT index and risk factors for dental caries, including city population and DI. The study included 4,305 12-year-old children living in 38 cities classified by demographic size as small, midsize and large. Zero-inflated negative binomial multilevel regression models were used to assess risk factors for DMFT and to address excess of zero DMFT and overdispersion through a Bayesian approach. The difference in the average level of DMFT among chi…

MaleDental Caries SusceptibilitySocial Determinants of HealthHealth BehaviorPopulationMothersOral HealthDental CariesVulnerable PopulationsSettore MED/01 - Statistica MedicaBeveragesFluoridesDental Caries SusceptibilityOverdispersionDietary SucroseRisk Factors12-year-old children Bayesian modelsCaries · Deprivation index Multilevel analysisHumansMedicineChildeducationGeneral DentistrySocioeconomic statuseducation.field_of_studyDMF Indexbusiness.industryMultilevel modelUrban HealthBayes TheoremRandom effects modelCariostatic Agentsstomatognathic diseasesCultural deprivationSocial deprivationItalySocial ClassCultural DeprivationEducational StatusFemalebusinessAttitude to HealthDemographyCaries Research
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Assessment of Susceptibility Risk Factors for ADHD in Imaging Genetic Studies

2019

Objective: ADHD consists of a count of symptoms that often presents heterogeneity due to overdispersion and excess of zeros. Statistical inference is usually based on a dichotomous outcome that is underpowered. The main goal of this study was to determine a suited probability distribution to analyze ADHD symptoms in Imaging Genetic studies. Method: We used two independent population samples of children to evaluate the consistency of the standard probability distributions based on count data for describing ADHD symptoms. Results: We showed that the zero-inflated negative binomial (ZINB) distribution provided the best power for modeling ADHD symptoms. ZINB reveals a genetic variant, rs273342…

MaleGenotypeImaging geneticsPopulationNegative binomial distributionPolymorphism Single NucleotideADHD symptomsImaging Genetics03 medical and health sciencesImaging Three-Dimensional0302 clinical medicineOverdispersionRisk FactorsStatisticsmental disordersDevelopmental and Educational PsychologyStatistical inferenceHumansGenetic Predisposition to Disease0501 psychology and cognitive sciencesGenetic TestingLongitudinal StudiesPoisson DistributionProspective Studiesp-valueMAPRE2Childeducationchildhoodzero-inflated negative binomialeducation.field_of_studyModels Statisticalbasal ganglia perivascular volumes05 social sciencesMagnetic Resonance Imagingcount dataVirchow-Robin spaceBinomial DistributionClinical PsychologyAttention Deficit Disorder with HyperactivityChild PreschoolProbability distributionFemalePsychology030217 neurology & neurosurgery050104 developmental & child psychologyCount data
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