Search results for "Vertebra"

showing 10 items of 1220 documents

Computational Fluid Dynamics Suggests Ecological Diversification among Stem-Gnathostomes.

2020

Summary The evolutionary assembly of the vertebrate bodyplan has been characterized as a long-term ecological trend toward increasingly active and predatory lifestyles, culminating in jawed vertebrates that dominate modern vertebrate biodiversity [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 ]. This contrast is no more stark than between the earliest jawed vertebrates and their immediate relatives, the extinct jawless, dermal armor-encased osteostracans, which have conventionally been interpreted as benthic mud-grubbers with poor swimming capabilities and low maneuverability [ 9 , 10 , 11 , 12 ]. Using computational fluid dynamics, we show that osteostracan headshield morphology is compatible with a dive…

0301 basic medicineWater flowcomputational fluid dynamicsBiologyDiversification (marketing strategy)General Biochemistry Genetics and Molecular BiologyPassive control03 medical and health sciences0302 clinical medicinebiology.animalAnimalsComputer Simulation14. Life underwatergeometric morphometricsSwimmingKey innovationEcologyFossilsFishesVertebrateBiodiversityFeeding BehaviorSubstrate (marine biology)jawed vertebratesBiological Evolution030104 developmental biologyBenthic zoneOblate spheroidHydrodynamicsecologyGeneral Agricultural and Biological Sciencesstem-gnathostomesHead030217 neurology & neurosurgeryEvolució (Biologia)Current biology : CB
researchProduct

Mitigating anticipated effects of systematic errors supports sister-group relationship between Xenacoelomorpha and Ambulacraria.

2019

International audience; Xenoturbella and the acoelomorph worms (Xenacoelomorpha) are simple marine animals with controversial affinities. They have been placed as the sister group of all other bilaterian animals (Nephrozoa hypothesis), implying their simplicity is an ancient characteristic ]; alternatively, they have been linked to the complex Ambulacraria (echinoderms and hemichordates) in a clade called the Xenambulacraria , suggesting their simplicity evolved by reduction from a complex ancestor. The difficulty resolving this problem implies the phylogenetic signal supporting the correct solution is weak and affected by inadequate modeling, creating a misleading non-phylogenetic signal. …

0301 basic medicineXenoturbellaAmbulacrariamedia_common.quotation_subjectAcoelomorpha ; Ambulacraria ; Metazoa ; Nephrozoa ; Phylogenomics ; Phylogeny ; Systematic Error ; XenoturbellaNephrozoaContext (language use)phylogeny[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomyGeneral Biochemistry Genetics and Molecular Biologysystematic error03 medical and health sciences0302 clinical medicineXenoturbellaAnimalsSimplicityAmbulacrariaChordatamedia_commonLong branch attractionbiologyMetazoa[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]Acoelomorphaphylogenomicsbiology.organism_classificationBiological EvolutionInvertebratesXenacoelomorpha[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology030104 developmental biologySister groupEvolutionary biologyOutgroupGeneral Agricultural and Biological Sciences030217 neurology & neurosurgeryEchinodermata
researchProduct

Bacterial community diversity harboured by interacting species

2016

International audience; All animals are infected by microbial partners that can be passengers or residents and influence many biological traits of their hosts. Even if important factors that structure the composition and abundance of microbial communities within and among host individuals have been recently described, such as diet, developmental stage or phylogeny, few studies have conducted cross-taxonomic comparisons, especially on host species related by trophic relationships. Here, we describe and compare the microbial communities associated with the cabbage root fly Delia radicum and its three major parasitoids: the two staphylinid beetles Aleochara bilineata and A. bipustulata and the…

0301 basic medicine[SDV]Life Sciences [q-bio]lcsh:MedicinespeciesArtificial Gene Amplification and ExtensionPathogenesisPathology and Laboratory MedicinephylogenycabbagegenusPolymerase Chain ReactiongeographyParasitoidAbundance (ecology)[ SDV.MP ] Life Sciences [q-bio]/Microbiology and ParasitologyMedicine and Health SciencesRickettsialcsh:ScienceTrophic levelMultidisciplinarybiologyEcologyMicrobiotabeetleGenomicsBiodiversityBacterial PathogensInsectsColeopterasymbiont[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologypyrosequencingMedical MicrobiologyHost-Pathogen Interactions[SDE]Environmental SciencesWolbachiaFrancePathogensmicrobial communityWolbachiaResearch ArticleArthropodaSpiroplasmaMollicutesSpiroplasmaMicrobial GenomicsResearch and Analysis MethodsMicrobiology03 medical and health sciencesPhylogeneticsGeneticsAnimals[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyMolecular Biology TechniquesMolecular BiologyMicrobial PathogensparasitoidBacteriaHost (biology)Dipteralcsh:RfungiOrganismsBiology and Life Sciencesbiology.organism_classificationInvertebratesHymenoptera030104 developmental biologylcsh:QMicrobiomeDelia radicum
researchProduct

SNPs in bone-related miRNAs are associated with the osteoporotic phenotype

2017

AbstractBiogenesis and function of microRNAs can be influenced by genetic variants in the pri-miRNA sequences leading to phenotypic variability. This study aims to identify single nucleotide polymorphisms (SNPs) affecting the expression levels of bone-related mature microRNAs and thus, triggering an osteoporotic phenotype. An association analysis of SNPs located in pri-miRNA sequences with bone mineral density (BMD) was performed in the OSTEOMED2 cohort (n = 2183). Functional studies were performed for assessing the role of BMD-associated miRNAs in bone cells. Two SNPs, rs6430498 in the miR-3679 and rs12512664 in the miR-4274, were significantly associated with femoral neck BMD. Further, we…

0301 basic medicineconformation:Diseases::Wounds and Injuries::Fractures Bone::Hip Fractures [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Phenotype [Medical Subject Headings]Polimorfismo de nucleótido simpleGene ExpressionboneOsteoblastosDensidad ósea:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Cohort StudiesGene Frequencysingle nucleotide polymorphismBone DensityBone cellOssosgeneticsFracturas osteoporóticasCells CulturedGeneticsBone mineralMicroARNsMultidisciplinarymicroRNAbiologyQalleleR:Diseases::Wounds and Injuries::Fractures Bone::Osteoporotic Fractures [Medical Subject Headings]clinical trialMiddle Agedcohort analysisPhenotypeHumanosFenotipmedicine.anatomical_structureCancellous BoneosteoblastMedicine:Diseases::Musculoskeletal Diseases::Bone Diseases [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]:Anatomy::Cells::Connective Tissue Cells::Osteoblasts [Medical Subject Headings]AlelosFenotipomusculoskeletal diseasesmedicine.medical_specialtyGenotypeScienceSingle-nucleotide polymorphismBiologychemistryPolymorphism Single NucleotideArticleBone and Bones:Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Cancellous Bone [Medical Subject Headings]03 medical and health sciencesCalcification PhysiologicInternal medicinemicroRNAmedicineHumanshumanproceduresAllele:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings]AllelesFemoral neckGenetic associationAgedcell culture:Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Bone Density [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism Genetic::Polymorphism Single Nucleotide [Medical Subject Headings]OsteoblastsEnfermedades óseasFracturas de caderaComputational BiologyCuello femoral:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Antisense Elements (Genetics)::RNA Antisense::MicroRNAs [Medical Subject Headings]MicroRNAs030104 developmental biologyEndocrinologymulticenter studybone mineralizationNucleic Acid ConformationOsteoporosispathology:Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Bones of Lower Extremity::Leg Bones::Femur::Femur Neck [Medical Subject Headings]TranscriptomemetabolismGenotipoFractures
researchProduct

Genomic characterization of the Braque Français type Pyrénées dog and relationship with other breeds

2018

The evaluation of genetic variability is a useful research tool for the correct management of selection and conservation strategies in dog breeds. In addition to pedigree genealogies, genomic data allow a deeper knowledge of the variability and genetic structure of populations. To date, many dog breeds, such as small regional breeds, still remain uncharacterized. Braque Français type Pyrénées (BRA) is a dog breed originating from a very old type of gun-dog used for pointing the location of game birds to hunters. Despite the ancient background, the knowledge about levels of genetic diversity, degree of inbreeding and population structure is scarce. This may raise concerns on the possibility …

0301 basic medicinedogsHeredityPopulation geneticsLinkage DisequilibriumDog Genetic diversity SNP Markers Braque Français type Pyrénées LUPA project Dog GenotypingDog Genetic diversitySettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoEffective population sizegenetic parametersInbreedingMammalseducation.field_of_studyGenomeMammalian GenomicsMultidisciplinaryEcologyPets and Companion AnimalsSNP MarkersQREukaryotaBraque Français type PyrénéesBreedLUPA projectVertebratesGenetic structureMedicineInbreedingResearch ArticleGenotypeEcological MetricsPopulation SizeScienceAnimal TypesPopulationSNPBiologyPolymorphism Single Nucleotidediversity03 medical and health sciencesPopulation MetricsEffective Population SizeGeneticsgenomicsAnimalsgenetic distancesGenetic variabilityeducationDog GenotypingBraque Français SNP array Genetic diversity and population structurePopulation DensityEvolutionary BiologyGenetic diversityWolvesPopulation BiologyEcology and Environmental SciencesOrganismsGenetic VariationBiology and Life Sciencesbraque françaisBayes TheoremSpecies DiversityGenetics Population030104 developmental biologyAnimal GenomicsEvolutionary biologyAmniotesZoologyPopulation Genetics
researchProduct

Tracking zoonotic pathogens using blood-sucking flies as 'flying syringes'

2017

About 60% of emerging infectious diseases in humans are of zoonotic origin. Their increasing number requires the development of new methods for early detection and monitoring of infectious agents in wildlife. Here, we investigated whether blood meals from hematophagous flies could be used to identify the infectious agents circulating in wild vertebrates. To this aim, 1230 blood-engorged flies were caught in the forests of Gabon. Identified blood meals (30%) were from 20 vertebrate species including mammals, birds and reptiles. Among them, 9% were infected by different extant malaria parasites among which some belonged to known parasite species, others to new parasite species or to parasite …

0301 basic medicineglobal healthForests[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisParasite hostingBiology (General)Pathogen2. Zero hungerEcologyGeneral NeuroscienceQRVertebrateGeneral Medicine3. Good healthTools and Resources[ SDV.MHEP.MI ] Life Sciences [q-bio]/Human health and pathology/Infectious diseasesBloodMedicineepidemiologyPlasmodium parasitesecologyQH301-705.5Science030106 microbiologyWildlifeEarly detectionZoologyBiologytsetse fliesGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesBlood suckingbiology.animalmedicineAnimalsParasitesGabonhematophagous flies[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyGeneral Immunology and MicrobiologyDipterafungimedicine.diseaseInsect Vectors[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology030104 developmental biologyEpidemiology and Global HealthVector (epidemiology)[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieOtherMalaria[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/SymbiosiseLife
researchProduct

The shell of the invasive bivalve species Dreissena polymorpha: biochemical, elemental and textural Investigations.

2016

28 pages; International audience; The zebra mussel Dreissena polymorpha is a well-established invasive model organism. Although extensively used in environmental sciences, virtually nothing is known of the molecular process of its shell calcification. By describing the microstructure, geochemistry and biochemistry/proteomics of the shell, the present study aims at promoting this species as a model organism in biomineralization studies, in order to establish a bridge with ecotoxicology, while sketching evolutionary conclusions. The shell of D. polymorpha exhibits the classical crossed-lamellar/complex crossed lamellar combination found in several heterodont bivalves, in addition to an extern…

0301 basic medicinelcsh:MedicineInvasive Species010501 environmental sciencesProteomicsEcotoxicology01 natural sciencesBiochemistrychemistry.chemical_compoundDatabase and Informatics MethodsMaterials PhysicsLectinsMusselslcsh:ScienceMicrostructureGel ElectrophoresisStainingMineralsMultidisciplinarybiologyOrganic CompoundsPhysicsMonosaccharidesBiological EvolutionEuropeChemistry[ SDV.BBM.GTP ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]Physical SciencesFranceSequence AnalysisResearch ArticleSilver StainingBivalvesMaterials ScienceShell (structure)CarbohydratesSequence DatabasesElectrophoretic StainingResearch and Analysis MethodsDreissenaDreissenaCoomassie Blue staining03 medical and health sciencesElectrophoretic TechniquesSpecies ColonizationAnimal Shells[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]Botany[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyEcotoxicologyAnimals[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology14. Life underwaterShell calcificationMolecular Biology TechniquesSequencing Techniques[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsMolecular Biology[ SDV.BBM ] Life Sciences [q-bio]/Biochemistry Molecular Biology0105 earth and related environmental scienceslcsh:ROrganic ChemistryEcology and Environmental SciencesOrganismsChemical CompoundsBiology and Life SciencesProteinsMolluscs[ SDV.IB.BIO ] Life Sciences [q-bio]/Bioengineering/Biomaterialsbiology.organism_classificationInvertebrates030104 developmental biologyCalcium carbonateBiological DatabaseschemistrySpecimen Preparation and TreatmentZebra mussellcsh:QIntroduced SpeciesBiomineralization
researchProduct

Maristem stem cells of marine/aquatic invertebrates: from basic research to innovative applications

2018

The “stem cells” discipline represents one of the most dynamic areas in biomedicine. While adult marine/aquatic invertebrate stem cell (MISC) biology is of prime research and medical interest, studies on stem cells from organisms outside the classical vertebrate (e.g., human, mouse, and zebrafish) and invertebrate (e.g., Drosophila, Caenorhabditis) models have not been pursued vigorously. Marine/aquatic invertebrates constitute the largest biodiversity and the widest phylogenetic radiation on Earth, from morphologically simple organisms (e.g., sponges, cnidarians), to the more complex mollusks, crustaceans, echinoderms, and protochordates. These organisms contain a kaleidoscope of MISC-type…

0301 basic medicinemarine/aquatic invertebratesQH301 Biologymarine/aquatic invertebrateBioactive moleculesT-NDASGeography Planning and Developmentlcsh:TJ807-830BiodiversitySettore BIO/05 - ZoologiaStem cellsblue biotechnology0302 clinical medicineBioactive moleculeBasic researchaging ; bioactive molecules ; blue biotechnology ; cancer ; cell culture ; COST Action ; Europe ; marine/aquatic invertebrates ; regeneration ; stem cellsGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)lcsh:Environmental sciencesCancerlcsh:GE1-350quinonessea-urchin eggsStem cellGeographyPolicy and LawEcologylcsh:Environmental effects of industries and plantsManagementEuropeMarine/aquatic invertebrateStem cellCèl·lules mareEuropean communityMonitoringaging; bioactive molecules; blue biotechnology; cancer; cell culture; COST Action; Europe; marine/aquatic invertebrates; regeneration; stem cellslcsh:Renewable energy sourcesCOST ActionAging; Bioactive molecules; Blue biotechnology; Cancer; Cell culture; COST Action; Europe; Marine/aquatic invertebrates; Regeneration; Stem cells; Geography Planning and Development; Renewable Energy Sustainability and the Environment; Management Monitoring Policy and LawManagement Monitoring Policy and LawBiologyQH30103 medical and health sciencesSDG 3 - Good Health and Well-beingNear neighborunitsstem cellsbioactive moleculesevolutioncancerSDG 14 - Life Below WaterRenewable Energy14. Life underwaterSH Aquaculture. Fisheries. AnglingSHRegeneration (ecology)BiologyBiomedicineInvertebratePlanning and Developmentcell cultureScience & TechnologySustainability and the EnvironmentRenewable Energy Sustainability and the Environmentbusiness.industryMarine invertebratesagingInvertebrats marinsbioactive moleculecell_developmental_biology030104 developmental biologylcsh:TD194-19513. Climate actionregenerationproteinbusiness030217 neurology & neurosurgery
researchProduct

Analysis of the relationship between the double transverse foramen and the possibility of developing clinical symptoms after whiplash

2017

Introduction: Currently there is no information about the possibility of developing clinical symptoms after whiplash in double transverse foramen subjects. Our aim was to test whether subjects with double transverse foramen have an increased risk of presenting with acute headache, dizziness, vertebral artery dissection, and vomiting after whiplash. Methods: We recorded the absence/presence of double transverse foramen, and the absence/presence of neck pain, acute headache, dizziness, vertebral artery dissection, and vomiting in 85 patients who had suffered whiplash injuries in car rear-end impacts in road traffic accidents. We used the odds ratio test to determine whether double transverse …

0301 basic medicinemedicine.medical_specialtyHistologyVertebral artery dissectionVertebral artery03 medical and health sciences0302 clinical medicinemedicine.arteryForamenWhiplashMedicineVertebrobasilar insufficiencybusiness.industryGeneral Medicinemedicine.diseaseSurgerymedicine.anatomical_structureAnesthesiaVomiting030101 anatomy & morphologyAnatomymedicine.symptombusinesshuman activities030217 neurology & neurosurgeryPost-Traumatic HeadacheCervical vertebraeClinical Anatomy
researchProduct

Vancomycin resistant Enterococcus faecium (VRE) vertebral osteomyelitis after uneventful spinal surgery: A case report and literature review

2017

Abstract Objective Case report and literature review. Background Enterococcus faecium is an emerging pathogen responsible for post procedural infections in patients who have undergone spinal decompression surgery. In this case report, the authors discuss and review recent literature on approaches to post-operative spinal infection. Case report We herein report the case of a 55-year-old HIV-negative Caucasian Italian woman who showed vertebral osteomyelitis with abscesses around the interbody cage caused by an Enterococcus faecium vancomycin resistant gen-Van A, following a Transforaminal Lumbar Interbody Fusion (TLIF). The same strain was detected in disc biopsy, urine culture and rectal sw…

0301 basic medicinemedicine.medical_specialtySettore MED/07 - Microbiologia E Microbiologia ClinicaEnterococcus faecium; Spinal surgery; Transforaminal Lumbar Interbody Fusion (TLIF); Vertebral osteomyelitis; Surgery; Neurology (clinical)Settore MED/17 - Malattie Infettive030106 microbiologyEnterococcus faeciumlcsh:Surgerylcsh:RC346-42903 medical and health sciencesEmerging pathogen0302 clinical medicineAntibiotic resistanceVertebral osteomyelitisBiopsymedicineVertebral osteomyelitislcsh:Neurology. Diseases of the nervous systemVancomycin resistant Enterococcus faeciumTransforaminal Lumbar Interbody Fusion (TLIF)medicine.diagnostic_testbiologybusiness.industrySettore MED/27 - Neurochirurgialcsh:RD1-811biology.organism_classificationmedicine.diseaseSpinal surgerySurgerySurgeryImplantSpinal surgeryNeurology (clinical)Vertebral osteomyelitibusiness030217 neurology & neurosurgeryEnterococcus faeciumInterdisciplinary Neurosurgery
researchProduct