Search results for "Vertebra"

showing 10 items of 1220 documents

Prevalence of anatomic variations of the atlas vertebra

2018

Abstract BACKGROUND CONTEXT The retrotransverse foramen (RTF), arcuate foramen (AF), unclosed transverse foramen (UTF) and posterior atlas arch defects (PAAD) are anatomic variations of the atlas vertebra that surgeons must be aware of before spine surgery is performed. PURPOSE To analyze the prevalence of the AF, RTF, UTF, and PAAD. STUDY DESIGN Ex-vivo anatomical study. PATIENT SAMPLE Two hundred eighteen atlas vertebrae obtained from 100 Caucasian subjects and 118 sub-Saharan African subjects (48 Sotho subjects, 35 Xhosa subjects and 35 Zulu subjects). METHODS We studied 218 atlas vertebrae from skeletons of the Raymond A. Dart Collection in order to analyze the prevalence of AF, RTF, UT…

Male0301 basic medicinemedicine.medical_specialtyBlack PeopleWhite PeopleAtlas vertebra03 medical and health sciences0302 clinical medicineSpine surgerymedicineForamenHumansOrthopedics and Sports MedicineCervical AtlasAtlas archGynecologyArcuate foramenSex Characteristicsbusiness.industryCervical AtlasAnatomic VariationOutcome measuresVertebramedicine.anatomical_structureFemaleSurgery030101 anatomy & morphologyNeurology (clinical)business030217 neurology & neurosurgeryThe Spine Journal
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Comparison of body mass index (BMI) with the CUN-BAE body adiposity estimator in the prediction of hypertension and type 2 diabetes

2016

BACKGROUND: Obesity is a world-wide epidemic whose prevalence is underestimated by BMI measurements, but CUN-BAE (Clínica Universidad de Navarra - Body Adiposity Estimator) estimates the percentage of body fat (BF) while incorporating information on sex and age, thus giving a better match. Our aim is to compare the BMI and CUN-BAE in determining the population attributable fraction (AFp) for obesity as a cause of chronic diseases. METHODS: We calculated the Pearson correlation coefficient between BMI and CUN-BAE, the Kappa index and the internal validity of the BMI. The risks of arterial hypertension (AHT) and diabetes mellitus (DM) and the AFp for obesity were assessed using both the BMI a…

Male:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Anthropometry [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings]ObesidadType 2 diabetesÍndice de masa corporalCUN-BAEBody Mass Index:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Diabetes mellitus0302 clinical medicineMedicine030212 general & internal medicineBody mass indexAdiposity:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]education.field_of_studyDiabetisAnthropometryDiabetes:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight::Obesity [Medical Subject Headings]Middle Aged:Anatomy::Tissues::Connective Tissue::Adipose Tissue [Medical Subject Headings]CausalityAdipose TissueBody fatHypertensionObesitatFemaleHipertensióResearch ArticleAdultmedicine.medical_specialty:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry::Body Weights and Measures::Body Mass Index [Medical Subject Headings]Population:Check Tags::Male [Medical Subject Headings]030209 endocrinology & metabolismBody adiposity index:Health Care::Environment and Public Health::Public Health::Epidemiologic Factors::Causality [Medical Subject Headings]03 medical and health sciences:Diseases::Cardiovascular Diseases::Vascular Diseases::Hypertension [Medical Subject Headings]Population attributable fractionClassification of obesityInternal medicineHipertensiónHumansObesityeducation:Persons::Persons::Age Groups::Adult [Medical Subject Headings]Aged:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Composition::Body Fat Distribution::Adiposity [Medical Subject Headings]Body volume indexbusiness.industryPublic Health Environmental and Occupational Health:Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus Type 2 [Medical Subject Headings]:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]medicine.diseaseObesityCross-Sectional StudiesEndocrinologyDiabetes Mellitus Type 2:Check Tags::Female [Medical Subject Headings]Attributable riskbusinessBody mass indexDemographyAntropometria
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Antilymphocyte Globulin for Prevention of Chronic Graft-versus-Host Disease.

2016

Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; BACKGROUND Chronic graft-versus-host disease (GVHD) is the leading cause of later illness and death after allogeneic hematopoietic stem-cell transplantation. We hypothesized that the inclusion of antihuman T-lymphocyte immune globulin (ATG) in a myeloablative conditioning regimen for patients with acute leukemia would result in a significant reduction in chronic GVHD 2 years after allogeneic peripheral-blood stem-cell transplantation from an HLA-identical sibling. METHODS We conducted a prospective, multicenter, open-label, randomized phase 3 study of ATG as part of …

Male:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Proportional Hazards Models [Medical Subject Headings]T-LymphocytesPhases of clinical researchGraft vs Host Disease:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]Linfocitos t:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Immunosuppressive Agent0302 clinical medicineTrasplante homólogoEstudios prospectivosMedicineCumulative incidenceProspective StudiesProspective cohort studyChildTransplantation Homologou:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Immune Sera::Antilymphocyte Serum [Medical Subject Headings]Acute leukemia:Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes Mononuclear::Lymphocytes::T-Lymphocytes [Medical Subject Headings]:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease [Medical Subject Headings]:Named Groups::Persons::Age Groups::Child::Child Preschool [Medical Subject Headings]Medicine (all)IncidenceSuero antilinfocíticoGeneral MedicineMiddle AgedModelos de riesgos proporcionales3. Good healthHumanosSurvival Rate030220 oncology & carcinogenesis:Named Groups::Persons::Age Groups::Adolescent [Medical Subject Headings]Child PreschoolFemale:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Immunologic Factors::Immunosuppressive Agents [Medical Subject Headings]Immunosuppressive AgentsHumanHomologousAdultmedicine.medical_specialty:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Prospective Studies [Medical Subject Headings]:Named Groups::Persons::Age Groups::Adult::Young Adult [Medical Subject Headings]AdolescentEnfermedad injerto contra huéspedDisease-Free Survival03 medical and health sciencesYoung AdultInternal medicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]HumansTransplantation HomologousSupervivencia sin enfermedadPreschoolSurvival rate:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Disease-Free Survival [Medical Subject Headings]:Named Groups::Persons::Age Groups::Child [Medical Subject Headings]Antilymphocyte SerumProportional Hazards ModelsTransplantationbusiness.industryEnfermedad crónicamedicine.diseaseInmunosupresoresAnti-thymocyte globulinSurgeryTransplantation:Diseases::Immune System Diseases::Graft vs Host Disease [Medical Subject Headings]Prospective Studie:Analytical Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures Operative::Transplantation::Transplantation Homologous [Medical Subject Headings]Graft-versus-host diseaseT-Lymphocyte:Check Tags::Female [Medical Subject Headings]Chronic DiseaseProportional Hazards ModelAdolescent; Adult; Antilymphocyte Serum; Child; Child Preschool; Chronic Disease; Disease-Free Survival; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Incidence; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Survival Rate; T-Lymphocytes; Transplantation Homologous; Young Adult; Medicine (all)business030215 immunology
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Gut microbiota steroid sexual dimorphism and its impact on gonadal steroids: influences of obesity and menopausal status

2020

[Background]: Gonadal steroid hormones have been suggested as the underlying mechanism responsible for the sexual dimorphism observed in metabolic diseases. Animal studies have also evidenced a causal role of the gut microbiome and metabolic health. However, the role of sexual dimorphism in the gut microbiota and the potential role of the microbiome in influencing sex steroid hormones and shaping sexually dimorphic susceptibility to disease have been largely overlooked. Although there is some evidence of sex-specific differences in the gut microbiota diversity, composition, and functionality, the results are inconsistent. Importantly, most of these studies have not taken into account the go…

Male:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings]PhysiologyGut flora:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Mice:Chemicals and Drugs::Hormones Hormone Substitutes and Hormone Antagonists::Hormones::Gonadal Hormones [Medical Subject Headings]0302 clinical medicineOverweight persons:Organisms::Eukaryota::Animals [Medical Subject Headings]TestosteroneProgesteronaGonadal Steroid HormonesTestosteronaTestosteroneProgesterone:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]Sex Characteristics0303 health sciencesMicrobiotaIntestins -- MalaltiesMiddle AgedSex ; Gender ; Gonadal steroids ; Testosterone ; Progesterone ; Microbiome ; Sexual dimorphism.Persones obeses3. Good healthMenopause:Phenomena and Processes::Microbiological Phenomena::Microbiota [Medical Subject Headings]Intestins -- MicrobiologiaCaracteres sexualeslcsh:QR100-130Female:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Climacteric::Menopause [Medical Subject Headings]SexAnimal studiesIntestines -- DiseasesMenopauseMenopausaAdultMicrobiology (medical):Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Sex Characteristics [Medical Subject Headings]:Check Tags::Male [Medical Subject Headings]SexoSteroid biosynthesisBiologyIntestines -- Microbiologydigestive systemMicrobiologylcsh:Microbial ecology:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies [Medical Subject Headings]03 medical and health sciencesSexual dimorphismmedicineAnimalsHumansObesityMicrobiome:Persons::Persons::Age Groups::Adult [Medical Subject Headings]Aged030304 developmental biology:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings]ResearchGender:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]medicine.diseasebiology.organism_classificationObesityGastrointestinal Microbiome:Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings]Gonadal steroidsSexual dimorphismCross-Sectional Studies:Check Tags::Female [Medical Subject Headings]Case-Control StudiesIdentidad de géneroMicrobiome030217 neurology & neurosurgeryMicrobiome
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Oral breathing and head posture

2006

Abstract Objective: To determine the head posture and cephalometric characteristics in oral breathing children. Materials and Methods: Lateral cephalograms taken in natural head posture of 35 oral breathing patients (OB) (mean age 8.8 ± 2.2 years SD; range 5–13 years) and of 35 patients with varied malocclusions and physiological breathing (PB) (mean age 9.7 ± 1.6 years SD; range 7–13 years) were examined. Results: A Student's t-test showed that an increase in angles NSL/OPT (P = .000), NSL/CVT (P = .001), FH/OPT (P = .000), FH/CVT (P = .005), and NSL/VER (P = .000); a decrease in the distance MGP-CV1p (P = .0001); and a decrease in the angles MGP/OP (P = .000) and OPT/ CVT (P = .036) were …

MaleAdolescentCephalometryPostureOrthodonticsMandibleNoseMaxillaMedicineHumansSella TurcicaChildOrthodonticsHead posturebusiness.industryRespiratory airwayOral breathingAirway ResistanceRespirationLateral cephalogramsHyoid boneHyoid BoneMean ageAnatomyMouth BreathingCraniometryChild PreschoolBreathingCervical VertebraeFemalebusinessHeadMalocclusion
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Longitudinal assessment of health-span and pre-death morbidity in wild type

2018

The increase in human life expectancy is accompanied by age-related cognitive and motor disability, thus raising the demand for strategies toward healthy aging. This requires understanding the biology of normal aging and late-life functional phenotypes. Genetic model organisms, such as Drosophila melanogaster, can help identifying evolutionary conserved mechanisms underlying aging. Longitudinal assessment of motor performance of more than 1000 individual flies revealed age-related motor performance decline and specific late-life motor disabilities. This allows defining heath- and ill-span and scoring late-life quality of individual flies. As in mammals, including humans, onset, duration, se…

MaleAgingdemographyfungiLongevityinvertebrate disabilityPhysical Functional Performancemotor behaviorDrosophila melanogasterModels AnimalAnimalsFemaleDrosophilaLongitudinal StudiesdietResearch PaperAging
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Quantitative analysis of modified functional muscle–bone unit and back muscle density in patients with lumbar vertebral fracture in Chinese elderly m…

2018

Objectives: Bone mineral density (BMD) is associated with muscle mass and quality, but little research has been done on functional muscle–bone unit and back muscle density in patients with lumbar vertebral fracture. This study used the “modified functional muscle–bone unit” concept and measured back muscle density to investigate muscle–bone interaction difference between the fracture and control group. Methods: This was a case–control study. A total of 52 elderly male patients (mean age 75 years) with lumbar vertebral fracture (cases) and 52 control healthy subjects were enrolled. Cross-sectional area (CSA) and density of paravertebral muscle were measured in quantitative computed tomograph…

MaleAgingmedicine.medical_specialtyChinaLumbar vertebral fractureUrology03 medical and health sciences0302 clinical medicineBone DensitymedicineOdds RatioHumansIn patient030212 general & internal medicineFunctional muscle–bone unitQuantitative computed tomographyQuantitative computed tomographyLumbar Vertebral FractureAgedFunctional muscle–bone unit · Muscle density · Lumbar vertebral fracture · Quantitative computed tomographyBone mineralAged 80 and overLumbar Vertebraemedicine.diagnostic_testbusiness.industryBack MusclesCase-control studyOdds ratioConfidence intervalCross-Sectional StudiesCase-Control StudiesMuscle densitySpinal FracturesGeriatrics and GerontologybusinessTomography X-Ray ComputedQuantitative analysis (chemistry)030217 neurology & neurosurgery
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Common variants of the liver fatty acid binding protein gene influence the risk of type 2 diabetes and insulin resistance in Spanish population.

2012

Journal Article; Research Support, Non-U.S. Gov't; SUMMARY The main objective was to evaluate the association between SNPs and haplotypes of the FABP1-4 genes and type 2 diabetes, as well as its interaction with fat intake, in one general Spanish population. The association was replicated in a second population in which HOMA index was also evaluated. METHODS 1217 unrelated individuals were selected from a population-based study [Hortega study: 605 women; mean age 54 y; 7.8% with type 2 diabetes]. The replication population included 805 subjects from Segovia, a neighboring region of Spain (446 females; mean age 52 y; 10.3% with type 2 diabetes). DM2 mellitus was defined in a similar way in b…

MaleAnatomy and PhysiologyEspañaDiabetes Mellitus Tipo 2:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]Type 2 diabetesResistencia a la InsulinaVariación Genética:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genotype::Haplotypes [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]EndocrinologyPolymorphism (computer science)Risk FactorsAnálisis de RegresiónFactores de Riesgo:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]Geneticseducation.field_of_studyMultidisciplinaryAdultoQRMiddle AgedCardiovascular Diseases:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus Type 2 [Medical Subject Headings]Regression AnalysisMedicineFemale:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Variation [Medical Subject Headings]Fatty Acid Binding Protein 3Research ArticleAdult:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation [Medical Subject Headings]GenotypeSciencePopulation:Check Tags::Male [Medical Subject Headings]Single-nucleotide polymorphismEndocrine SystemBiologyFatty Acid-Binding ProteinsPolymorphism Single Nucleotide:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance [Medical Subject Headings]Insulin resistanceGenetic variation:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]medicineGeneticsHumans:Named Groups::Persons::Age Groups::Adult::Aged [Medical Subject Headings]education:Diseases::Cardiovascular Diseases [Medical Subject Headings]Biology:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings]AllelesAgedDiabetic Endocrinology:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Regression Analysis [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism Genetic::Polymorphism Single Nucleotide [Medical Subject Headings]Polymorphism GeneticEndocrine PhysiologyHaplotypeGenetic Variation:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism Genetic [Medical Subject Headings]medicine.diseaseObesity:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Carrier Proteins::Fatty Acid-Binding Proteins [Medical Subject Headings]:Check Tags::Female [Medical Subject Headings]Diabetes Mellitus Type 2HaplotypesSpainMetabolic DisordersMutationInsulin ResistancePopulation GeneticsPloS one
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Pet dogs' behavior when the owner and an unfamiliar person attend to a faux rival.

2017

While dog owners ascribe different emotions to their pets, including jealousy, research on secondary emotions in nonhuman animals is very limited and, so far, only one study has investigated jealousy in dogs (Canis familiaris). This work explores jealousy in dogs one step further. We conducted two studies adapting a procedure devised to assess jealousy in human infants. In each study 36 adult dogs were exposed to a situation in which their owner and a stranger ignored them while directing positive attention towards three different objects: a book, a puppet and a fake dog (Study 1: furry; Study 2: plastic). Overall, the results of both studies do not provide evidence that the behavioral resp…

MaleAnimal TypesEmotionsSocial Scienceslcsh:MedicineInterpersonal RelationshipsVocalizationDogsJealousySociologyAnimalsHumansPsychologylcsh:ScienceAnimal Signaling and CommunicationMammalsAnalysis of VarianceBehaviorBehavior AnimalAnimal BehaviorPets and Companion AnimalsHuman-Animal Bondlcsh:ROrganismsBiology and Life SciencesEukaryotaPlay and PlaythingsCollective Human BehaviorVertebratesAmniotesSocial SystemsFemalelcsh:QZoologyResearch ArticlePLoS ONE
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Executive Functions Profile in Extreme Eating/Weight Conditions : From Anorexia Nervosa to Obesity

2012

Background: Extreme weight conditions (EWC) groups along a continuum may share some biological risk factors and intermediate neurocognitive phenotypes. A core cognitive trait in EWC appears to be executive dysfunction, with a focus on decision making, response inhibition and cognitive flexibility. Differences between individuals in these areas are likely to contribute to the differences in vulnerability to EWC. The aim of the study was to investigate whether there is a common pattern of executive dysfunction in EWC while comparing anorexia nervosa patients (AN), obese subjects (OB) and healthy eating/weight controls (HC). Methods: Thirty five AN patients, fifty two OB and one hundred thirty…

MaleAnorexia NervosaEating DisordersObesidadNeuropsychological TestsAudiologySocial and Behavioral Sciences:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Executive FunctionCognitionCognitive neurologyWisconsin Card Sorting TestImagen CorporalHuman PerformancePsychology:Psychiatry and Psychology::Mental Disorders::Eating Disorders::Anorexia Nervosa [Medical Subject Headings]Anorexia NerviosaPsychiatryMultidisciplinaryQCognitive flexibilityRNeuropsychological testingAnorèxia nerviosaMiddle AgedExecutive functionsToma de ConcienciaClinical PsychologyMental HealthPruebas NeuropsicológicasAnorexia nervosa (differential diagnoses)Eating disordersMedicineObesitatFemalemedicine.symptomConducta compulsivaResearch ArticleAdultmedicine.medical_specialtyImpulsivityAdolescentScienceDecision MakingPes corporalBiologyImpulsivityYoung AdultNeuropsychologymedicineHumansObesityTrastorns de la conducta alimentàriaNutritionBehavior:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Cognition::Awareness [Medical Subject Headings]Trastorno por Déficit de Atención con HiperactividadAnorexia nervosaBody weight:Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings]Impulsive Behavior:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Tests [Medical Subject Headings]:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Body Image [Medical Subject Headings]NeurocognitiveDecision making:Psychiatry and Psychology::Mental Disorders::Mental Disorders Diagnosed in Childhood::Attention Deficit and Disruptive Behavior Disorders::Attention Deficit Disorder with Hyperactivity [Medical Subject Headings]Stroop effectExecutive dysfunction
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