Search results for "Vertebrate"

showing 10 items of 830 documents

Genetic tools discriminate strains of Leishmania infantum isolated from  humans and dogs in Sicily, Italy

2020

Background Leishmaniasis is one of the most important vector-borne diseases and it represents a serious world health problem affecting millions of people. High levels of Leishmania infections, affecting both humans and animals, are recognized among Italian regions. Among these, Sicily has one of the highest prevalence of Leishmania infection. Methodology/Principal Findings Seventy-eight Leishmania strains isolated from human and animal samples across Sicily, were analyzed for the polymorphic k26-gene and genotypes were assigned according to the size of the PCR products. A multilocus microsatellite typing (MLMT) approach based on the analysis of 11 independent loci was used to investigate po…

0301 basic medicineRC955-962Population genetics0302 clinical medicineMedical ConditionsArctic medicine. Tropical medicineZoonosesMedicine and Health SciencesDog DiseasesLeishmaniasisGeneticsProtozoansLeishmaniaMammalseducation.field_of_studyGeographyEukaryotaInfectious DiseasesItalyVertebratesMicrosatelliteLeishmaniasis VisceralLeishmania infantumPublic aspects of medicineRA1-1270Research ArticleNeglected Tropical DiseasesLeishmania Infantum030231 tropical medicinePopulationBiology03 medical and health sciencesDogsParasitic DiseasesGeneticsAnimalsHumansTypingGenetic variabilityeducationGenetic diversityEvolutionary BiologyProtozoan InfectionsPopulation BiologyPublic Health Environmental and Occupational HealthOrganismsBiology and Life SciencesHuman GeneticsLeishmaniabiology.organism_classificationTropical DiseasesParasitic Protozoans030104 developmental biologyAmniotesEarth SciencesZoologyPopulation GeneticsPLoS Neglected Tropical Diseases
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Contrasting coping styles meet the wall: A dopamine driven dichotomy in behavior and cognition

2017

Individual variation in the ability to modify previously learned behaviour is an important dimension of trait correlations referred to as coping styles, behavioral syndromes or personality. These trait clusters have been shaped by natural selection, and underlying control mechanisms are often conserved throughout vertebrate evolution. In teleost fishes, behavioral flexibility and coping style have been studied in the high (HR) and low-responsive (LR) rainbow trout lines. Generally, proactive LR trout show a behaviour guided by previously learned routines, while HR trout show a more flexible behaviour relying on environmental cues. In mammals, routine dependent vs flexible behavior has been …

0301 basic medicineSTRESSNEUROSCIENCESTELEOST FISHESFLEXIBILITYRAINBOW-TROUTINDIVIDUAL VARIATIONteleostsAmygdalacognitive flexibilitylcsh:RC321-571Developmental psychology03 medical and health sciencesBehavioral syndrome0302 clinical medicineLimbic systemmonoamineslimbic systembiology.animalNeuroplasticitymedicine14. Life underwaterlcsh:Neurosciences. Biological psychiatry. NeuropsychiatryOriginal ResearchbiologyDANIO-RERIOGeneral NeuroscienceCognitive flexibilityVertebrateNEURAL PLASTICITYbiology.organism_classificationRECEPTORSAMYGDALATrout030104 developmental biologymedicine.anatomical_structurepersonalityANIMAL PERSONALITIESRainbow troutNeuroscience030217 neurology & neurosurgeryNeuroscience
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Under pressure: phenotypic divergence and convergence associated with microhabitat adaptations in Triatominae

2021

AbstractBackgroundTriatomine bugs, the vectors of Chagas disease, associate with vertebrate hosts in highly diverse ecotopes. When these blood-sucking bugs adapt to new microhabitats, their phenotypes may change. Although understanding phenotypic variation is key to the study of adaptive evolution and central to phenotype-based taxonomy, the drivers of phenotypic change and diversity in triatomines remain poorly understood.Methods/FindingsWe combined a detailed phenotypic appraisal (including morphology and morphometrics) with mitochondrialcytband nuclear ITS2 DNA-sequence analyses to studyRhodnius ecuadoriensispopulations from across the species’ range. We found three major, naked-eye phen…

0301 basic medicineSystematicsEntomologyChagas diseaseRange (biology)030231 tropical medicineRhodniuslcsh:Infectious and parasitic diseases03 medical and health sciences0302 clinical medicineNestbiology.animalSystematicsPeruparasitic diseasesGeneticsAnimalsHumanslcsh:RC109-216Selection GeneticTriatominaeEcosystemPhylogenyMorphometricsPhylogenetic treebiologyResearchCorrectionVertebratePhenotypic traitbiology.organism_classificationAdaptation PhysiologicalBiological EvolutionInsect VectorsPhylogeography030104 developmental biologyInfectious DiseasesPhenotypeHabitatEvolutionary biologyRhodniusParasitologyTaxonomy (biology)EcuadorTriatominaeMorphometricsParasites & Vectors
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Impact of temperature and soil type on Mycobacterium bovis survival in the environment

2017

Mycobacterium bovis, the causative agent of the bovine tuberculosis (bTB), mainly affects cattle, its natural reservoir, but also a wide range of domestic and wild mammals. Besides direct transmission via contaminated aerosols, indirect transmission of the M. bovis between wildlife and livestock might occur by inhalation or ingestion of environmental substrates contaminated through infected animal shedding. We monitored the survival of M. bovis in two soil samples chosen for their contrasted physical and-chemical properties (i.e. pH, clay content). The population of M. bovis spiked in sterile soils was enumerated by a culture-based method after 14, 30, 60, 90, 120 and 150 days of incubation…

0301 basic medicineVeterinary medicineTime FactorsPulmonology[SDV]Life Sciences [q-bio]lcsh:MedicineArtificial Gene Amplification and ExtensionSoil ChemistryPolymerase Chain ReactionSoilZoonosesMedicine and Health SciencesBovine Tuberculosislcsh:ScienceDNA extractionIncubationMammals2. Zero hungereducation.field_of_studyMycobacterium bovisMultidisciplinaryTemperatureSoil chemistryAgricultureRuminantsSoil typeActinobacteriaChemistrymycobacterium bovisInfectious DiseasesPhysical SciencesVertebratesLivestocktuberculinResearch ArticleLivestock030106 microbiologyPopulationSoil ScienceTuberculinBiology03 medical and health sciencesExtraction techniquesBovinesEnvironmental ChemistryAnimalsNatural reservoirMolecular Biology TechniqueseducationMolecular BiologytuberculineMicrobial Viability[ SDV ] Life Sciences [q-bio]Bacteriabusiness.industrylcsh:REcology and Environmental SciencesOrganismsBiology and Life Sciencesbiology.organism_classificationResearch and analysis methods13. Climate actionAmniotesRespiratory Infectionstuberculose bovinelcsh:QCattlebusiness
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Evaluation of Immunofluorescence Antibody Test Used for the Diagnosis of Canine Leishmaniasis in the Mediterranean Basin: A Systematic Review and Met…

2015

With an expected sensitivity (Se) of 96% and specificity (Sp) of 98%, the immunofluorescence antibody test (IFAT) is frequently used as a reference test to validate new diagnostic methods and estimate the canine leihmaniasis (CanL) true prevalence in the Mediterranean basin. To review the diagnostic accuracy of IFAT to diagnose CanL in this area with reference to its Se and Sp and elucidate the potential causes of their variations, a systematic review was conducted (31 studies for the 26-year period). Three IFAT validation methods stood out: the classical contingency table method, methods based on statistical models and those based on experimental studies. A variation in the IFAT Se and Sp …

0301 basic medicineVeterinary medicinelcsh:MedicineArtificial Gene Amplification and ExtensionPolymerase Chain ReactionMediterranean BasinMathematical and Statistical Techniques0302 clinical medicineZoonosesMedicine and Health SciencesCanine leishmaniasisDog Diseaseslcsh:ScienceLeishmaniasisMammalsMultidisciplinaryGeographymedicine.diagnostic_testMediterranean RegionGeographical regionsRegional geographyResearch AssessmentInfectious DiseasesFluorescent Antibody Technique DirectMeta-analysisVertebratesPhysical Sciencesmedicine.symptomStatistics (Mathematics)Research ArticleNeglected Tropical DiseasesSystematic Reviews030231 tropical medicine030106 microbiologyResearch and Analysis MethodsImmunofluorescenceSensitivity and SpecificityAsymptomatic03 medical and health sciencesDogsparasitic diseasesParasitic DiseasesmedicineAnimalsStatistical MethodsMolecular Biology TechniquesMolecular BiologyProtozoan Infectionsbusiness.industrylcsh:RfungiOrganismsReproducibility of ResultsBiology and Life SciencesLeishmaniasisGold standard (test)Tropical Diseasesmedicine.diseaseEarth sciencesParasitologyAmniotesImmunologyMediterranean BasinParasitologylcsh:QbusinessMathematicsMeta-AnalysisPLOS ONE
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Computational Fluid Dynamics Suggests Ecological Diversification among Stem-Gnathostomes.

2020

Summary The evolutionary assembly of the vertebrate bodyplan has been characterized as a long-term ecological trend toward increasingly active and predatory lifestyles, culminating in jawed vertebrates that dominate modern vertebrate biodiversity [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 ]. This contrast is no more stark than between the earliest jawed vertebrates and their immediate relatives, the extinct jawless, dermal armor-encased osteostracans, which have conventionally been interpreted as benthic mud-grubbers with poor swimming capabilities and low maneuverability [ 9 , 10 , 11 , 12 ]. Using computational fluid dynamics, we show that osteostracan headshield morphology is compatible with a dive…

0301 basic medicineWater flowcomputational fluid dynamicsBiologyDiversification (marketing strategy)General Biochemistry Genetics and Molecular BiologyPassive control03 medical and health sciences0302 clinical medicinebiology.animalAnimalsComputer Simulation14. Life underwatergeometric morphometricsSwimmingKey innovationEcologyFossilsFishesVertebrateBiodiversityFeeding BehaviorSubstrate (marine biology)jawed vertebratesBiological Evolution030104 developmental biologyBenthic zoneOblate spheroidHydrodynamicsecologyGeneral Agricultural and Biological Sciencesstem-gnathostomesHead030217 neurology & neurosurgeryEvolució (Biologia)Current biology : CB
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Mitigating anticipated effects of systematic errors supports sister-group relationship between Xenacoelomorpha and Ambulacraria.

2019

International audience; Xenoturbella and the acoelomorph worms (Xenacoelomorpha) are simple marine animals with controversial affinities. They have been placed as the sister group of all other bilaterian animals (Nephrozoa hypothesis), implying their simplicity is an ancient characteristic ]; alternatively, they have been linked to the complex Ambulacraria (echinoderms and hemichordates) in a clade called the Xenambulacraria , suggesting their simplicity evolved by reduction from a complex ancestor. The difficulty resolving this problem implies the phylogenetic signal supporting the correct solution is weak and affected by inadequate modeling, creating a misleading non-phylogenetic signal. …

0301 basic medicineXenoturbellaAmbulacrariamedia_common.quotation_subjectAcoelomorpha ; Ambulacraria ; Metazoa ; Nephrozoa ; Phylogenomics ; Phylogeny ; Systematic Error ; XenoturbellaNephrozoaContext (language use)phylogeny[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomyGeneral Biochemistry Genetics and Molecular Biologysystematic error03 medical and health sciences0302 clinical medicineXenoturbellaAnimalsSimplicityAmbulacrariaChordatamedia_commonLong branch attractionbiologyMetazoa[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]Acoelomorphaphylogenomicsbiology.organism_classificationBiological EvolutionInvertebratesXenacoelomorpha[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology030104 developmental biologySister groupEvolutionary biologyOutgroupGeneral Agricultural and Biological Sciences030217 neurology & neurosurgeryEchinodermata
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Bacterial community diversity harboured by interacting species

2016

International audience; All animals are infected by microbial partners that can be passengers or residents and influence many biological traits of their hosts. Even if important factors that structure the composition and abundance of microbial communities within and among host individuals have been recently described, such as diet, developmental stage or phylogeny, few studies have conducted cross-taxonomic comparisons, especially on host species related by trophic relationships. Here, we describe and compare the microbial communities associated with the cabbage root fly Delia radicum and its three major parasitoids: the two staphylinid beetles Aleochara bilineata and A. bipustulata and the…

0301 basic medicine[SDV]Life Sciences [q-bio]lcsh:MedicinespeciesArtificial Gene Amplification and ExtensionPathogenesisPathology and Laboratory MedicinephylogenycabbagegenusPolymerase Chain ReactiongeographyParasitoidAbundance (ecology)[ SDV.MP ] Life Sciences [q-bio]/Microbiology and ParasitologyMedicine and Health SciencesRickettsialcsh:ScienceTrophic levelMultidisciplinarybiologyEcologyMicrobiotabeetleGenomicsBiodiversityBacterial PathogensInsectsColeopterasymbiont[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologypyrosequencingMedical MicrobiologyHost-Pathogen Interactions[SDE]Environmental SciencesWolbachiaFrancePathogensmicrobial communityWolbachiaResearch ArticleArthropodaSpiroplasmaMollicutesSpiroplasmaMicrobial GenomicsResearch and Analysis MethodsMicrobiology03 medical and health sciencesPhylogeneticsGeneticsAnimals[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyMolecular Biology TechniquesMolecular BiologyMicrobial PathogensparasitoidBacteriaHost (biology)Dipteralcsh:RfungiOrganismsBiology and Life Sciencesbiology.organism_classificationInvertebratesHymenoptera030104 developmental biologylcsh:QMicrobiomeDelia radicum
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SNPs in bone-related miRNAs are associated with the osteoporotic phenotype

2017

AbstractBiogenesis and function of microRNAs can be influenced by genetic variants in the pri-miRNA sequences leading to phenotypic variability. This study aims to identify single nucleotide polymorphisms (SNPs) affecting the expression levels of bone-related mature microRNAs and thus, triggering an osteoporotic phenotype. An association analysis of SNPs located in pri-miRNA sequences with bone mineral density (BMD) was performed in the OSTEOMED2 cohort (n = 2183). Functional studies were performed for assessing the role of BMD-associated miRNAs in bone cells. Two SNPs, rs6430498 in the miR-3679 and rs12512664 in the miR-4274, were significantly associated with femoral neck BMD. Further, we…

0301 basic medicineconformation:Diseases::Wounds and Injuries::Fractures Bone::Hip Fractures [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Phenotype [Medical Subject Headings]Polimorfismo de nucleótido simpleGene ExpressionboneOsteoblastosDensidad ósea:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Cohort StudiesGene Frequencysingle nucleotide polymorphismBone DensityBone cellOssosgeneticsFracturas osteoporóticasCells CulturedGeneticsBone mineralMicroARNsMultidisciplinarymicroRNAbiologyQalleleR:Diseases::Wounds and Injuries::Fractures Bone::Osteoporotic Fractures [Medical Subject Headings]clinical trialMiddle Agedcohort analysisPhenotypeHumanosFenotipmedicine.anatomical_structureCancellous BoneosteoblastMedicine:Diseases::Musculoskeletal Diseases::Bone Diseases [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]:Anatomy::Cells::Connective Tissue Cells::Osteoblasts [Medical Subject Headings]AlelosFenotipomusculoskeletal diseasesmedicine.medical_specialtyGenotypeScienceSingle-nucleotide polymorphismBiologychemistryPolymorphism Single NucleotideArticleBone and Bones:Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Cancellous Bone [Medical Subject Headings]03 medical and health sciencesCalcification PhysiologicInternal medicinemicroRNAmedicineHumanshumanproceduresAllele:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings]AllelesFemoral neckGenetic associationAgedcell culture:Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Bone Density [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism Genetic::Polymorphism Single Nucleotide [Medical Subject Headings]OsteoblastsEnfermedades óseasFracturas de caderaComputational BiologyCuello femoral:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Antisense Elements (Genetics)::RNA Antisense::MicroRNAs [Medical Subject Headings]MicroRNAs030104 developmental biologyEndocrinologymulticenter studybone mineralizationNucleic Acid ConformationOsteoporosispathology:Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Bones of Lower Extremity::Leg Bones::Femur::Femur Neck [Medical Subject Headings]TranscriptomemetabolismGenotipoFractures
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Genomic characterization of the Braque Français type Pyrénées dog and relationship with other breeds

2018

The evaluation of genetic variability is a useful research tool for the correct management of selection and conservation strategies in dog breeds. In addition to pedigree genealogies, genomic data allow a deeper knowledge of the variability and genetic structure of populations. To date, many dog breeds, such as small regional breeds, still remain uncharacterized. Braque Français type Pyrénées (BRA) is a dog breed originating from a very old type of gun-dog used for pointing the location of game birds to hunters. Despite the ancient background, the knowledge about levels of genetic diversity, degree of inbreeding and population structure is scarce. This may raise concerns on the possibility …

0301 basic medicinedogsHeredityPopulation geneticsLinkage DisequilibriumDog Genetic diversity SNP Markers Braque Français type Pyrénées LUPA project Dog GenotypingDog Genetic diversitySettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoEffective population sizegenetic parametersInbreedingMammalseducation.field_of_studyGenomeMammalian GenomicsMultidisciplinaryEcologyPets and Companion AnimalsSNP MarkersQREukaryotaBraque Français type PyrénéesBreedLUPA projectVertebratesGenetic structureMedicineInbreedingResearch ArticleGenotypeEcological MetricsPopulation SizeScienceAnimal TypesPopulationSNPBiologyPolymorphism Single Nucleotidediversity03 medical and health sciencesPopulation MetricsEffective Population SizeGeneticsgenomicsAnimalsgenetic distancesGenetic variabilityeducationDog GenotypingBraque Français SNP array Genetic diversity and population structurePopulation DensityEvolutionary BiologyGenetic diversityWolvesPopulation BiologyEcology and Environmental SciencesOrganismsGenetic VariationBiology and Life Sciencesbraque françaisBayes TheoremSpecies DiversityGenetics Population030104 developmental biologyAnimal GenomicsEvolutionary biologyAmniotesZoologyPopulation Genetics
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