Search results for "Vitamin A"

showing 10 items of 84 documents

In vivo studies of altered expression patterns of p53 and proliferative control genes in chronic vitamin A deficiency and hypervitaminosis

2003

Several clinical trials have revealed that individuals who were given beta-carotene and vitamin A did not have a reduced risk of cancer compared to those given placebo; rather, vitamin A could actually have caused an adverse effect in the lungs of smokers [Omenn, G.S., Goodman, G.E., Thornquist, M.D., Balmes, J., Cullen, M.R., Glass, A., Keogh, J.P., Meyskens, F.L., Valanis, B., Williams, J.H., Barnhart, S. & Hammar, S. N. Engl. J. Med (1996) 334, 1150-1155; Hennekens, C.H., Buring, J.E., Manson, J.E., Stampfer, M., Rosner, B., Cook, N.R., Belanger, C., LaMotte, F., Gaziano, J.M., Ridker, P.M., Willet, W. & Peto, R. (1996) N. Engl. J. Med. 334, 1145-1149]. Using differential display techniq…

Cyclin-Dependent Kinase Inhibitor p21VitaminRetinyl Estersmedicine.medical_specialtyMacromolecular SubstancesProto-Oncogene Proteins c-junReceptors Retinoic AcidBlotting WesternRetinoic acidBiologymedicine.disease_causeBiochemistrychemistry.chemical_compoundIn vivoCyclinsInternal medicinemedicineAnimalsHypervitaminosis ARNA MessengerRats WistarVitamin AReceptorLungDifferential displayReverse Transcriptase Polymerase Chain ReactionVitamin A DeficiencyGene Expression ProfilingDNAmedicine.diseaseHypervitaminosisPrecipitin TestsRatsVitamin A deficiencyEndocrinologyGene Expression RegulationLiverchemistryChronic DiseaseImmunologyDiterpenesTumor Suppressor Protein p53CarcinogenesisCell DivisionEuropean Journal of Biochemistry
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Vegetable and Fruit Intakes Are Associated with hs-CRP Levels in Pre-Pubertal Girls

2017

The influence of diet on inflammation in children remains unclear. We aimed to analyze the influence of diet on high-sensitivity C-reactive protein (hs-CRP) levels in a pre-pubertal population free of other influences that may affect hs-CRP levels. We determined hs-CRP levels in 571 six- to eight-year-old children using an hs-CRP ELISA kit. Information on food and nutrient intake was obtained through a food-frequency questionnaire. Overall dietary quality was assessed using the Healthy Eating Index (HEI). We found that girls in the highest tertile of hs-CRP levels had a higher intake of saturated fatty acid, and lower intakes of fiber and vitamin E and a lower HEI score when compared to tho…

Dietary FiberMale0301 basic medicineCross-sectional studymedicine.medical_treatmentAdolescentsBody Mass Indexchemistry.chemical_compoundhs-CRP levelsSurveys and QuestionnairesVegetablesVitamin EMedicinepre-pubertal childrenFood scienceChildVitamin Ahs-CRP levels; pre-pubertal children; fibre intake; vegetable intake; fruit intake; antioxidantseducation.field_of_studyNutrition and DieteticsbiologyFatty Acidsfibre intakeC-Reactive ProteinantioxidantsSaturated fatty acidFemaleDietalcsh:Nutrition. Foods and food supplyVitaminPopulationlcsh:TX341-641Article03 medical and health sciencesfruit intakeFood Qualityvegetable intakeHumanseducationInflammation030109 nutrition & dieteticsbusiness.industryVitamin EPubertyC-reactive proteinDietCross-Sectional StudiesSocioeconomic FactorschemistryFruitbiology.proteinbusinessFood qualityBody mass indexFood ScienceNutrients
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Are the Recommended Dietary Allowances for Vitamins Appropriate for Elderly People?

2015

Background: An adequate vitamin intake is essential for a good nutritional status, especially in older women, who are more sensitive to nutritional deficiencies. The American, European and Italian Recommended Dietary Allowances (RDAs) derive mainly from studies on adults, and it is not clear whether they also apply to elderly people. Comparing the RDAs with the actual vitamin intake of a group of healthy older women could help to clarify the real needs of elderly people. Objective: Our aim was to compare the American, European, and Italian RDAs with the actual vitamin intake of a group of healthy older women. Design: This was a cross-sectional study. Participants: The study included 286 hea…

Dietary FiberRiboflavinRiboflavinAscorbic AcidRecommended Dietary AllowancesPantothenic AcidBody Mass Indexchemistry.chemical_compoundPantothenic acid80 and overMicronutrientMicronutrientsMicronutrient; Older people; Recommended Dietary Allowances (RDA); Vitamins; Aged; Aged 80 and over; Ascorbic Acid; Body Mass Index; Body Weight; Cross-Sectional Studies; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Proteins; Energy Intake; Female; Folic Acid; Humans; Micronutrients; Nutrition Assessment; Nutritional Status; Pantothenic Acid; Portion Size; Riboflavin; Vitamin A; Vitamin B 12; Vitamin B 6; Recommended Dietary Allowances; Food Science; Nutrition and Dietetics; Medicine (all)Vitamin AAged 80 and overNutrition and DieteticsMedicine (all)General MedicineVitaminsMicronutrientVitamin B 12FemaleDietary ProteinsVitaminNutritional Statusvitamis elderlyFolic AcidEnvironmental healthmedicineRecommended Dietary Allowances (RDAs)Dietary CarbohydratesHumansAgedRecommended Dietary Allowances (RDA)business.industryBody WeightPortion SizeRetinol Equivalentmedicine.diseaseAscorbic acidDietary FatsVitamin B 6MalnutritionCross-Sectional StudiesNutrition AssessmentchemistryOlder peoplebusinessEnergy IntakeBody mass indexFood Science
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Primary culture of avian embryonic heart forming region cells to study the regulation of vertebrate early heart morphogenesis by vitamin A

2014

Background: Important knowledge about the role of vitamin A in vertebrate heart development has been obtained using the vitamin A-deficient avian in ovo model which enables the in vivo examination of very early stages of vertebrate heart morphogenesis. These studies have revealed the critical role of the vitamin A-active form, retinoic acid (RA) in the regulation of several developmental genes, including the important growth regulatory factor, transforming growth factor-beta2 (TGFβ2), involved in early events of heart morphogenesis. However, this in ovo model is not readily available for elucidating details of molecular mechanisms determining RA activity, thus limiting further examination o…

Early cardiovascular developmentVascular Endothelial Growth Factor AHeart morphogenesisRetinoic acidMorphogenesisEnzyme-Linked Immunosorbent AssayTretinoinChick EmbryoBiologyAvian ProteinsTissue Culture Techniqueschemistry.chemical_compoundTransforming Growth Factor beta2Gene expressionin vitro cultureRetinoic acidMorphogenesisAnimalsVitamin ACells CulturedGeneticsHomeodomain ProteinsEmbryonic heartHeart developmentGATA4Reverse Transcriptase Polymerase Chain ReactionTGFβ2MyocardiumGene Expression Regulation DevelopmentalHeartVitaminsChicken heart forming region cellsFibronectinsGATA4 Transcription Factor:NATURAL SCIENCES::Biology [Research Subject Categories]chemistryVertebratesDevelopmental biologyChickensDevelopmental BiologyResearch ArticleTranscription FactorsBMC Developmental Biology
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Vitamin A modulates the effects of thyroid hormone on UDP-glucuronosyltransferase expression and activity in rat liver.

2002

We studied the influence of thyroid hormones and vitamin A status on the regulation of UDP-glucuronosyltransferase (UGT) expression and the glucuronidation of thyroid hormones by UGTs. For this, we used an original model of rats fed with different vitamin A diets and implanted subcutaneously by osmotic minipumps delivering vehicle or thyroid hormones, which permitted the control of plasma thyroid hormone concentrations. The activity and expression of family 1 UGTs are correlated and were significantly modified by both thyroid status and amounts of retinol in the diet. Dietary vitamin A did not perturbe the UGT1A expression in thyroidectomized animals. Thyroid hormones and dietary vitamin A …

Gene isoformVitaminMaleendocrine systemmedicine.medical_specialtyThyroid Hormonesendocrine system diseasesMonosaccharide Transport ProteinsBilirubinGlucuronidationNaphtholsBiologydigestive systemBiochemistryGene Expression Regulation Enzymologicchemistry.chemical_compoundEndocrinologyInternal medicinemedicineAnimalsGlucuronosyltransferaseRats WistarVitamin AMolecular BiologyThyroidRetinolBilirubinDietRatsThyroxinemedicine.anatomical_structureEndocrinologychemistryLiverThyroid hormonesThyroidectomyTriiodothyronineHormoneMolecular and cellular endocrinology
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Vitamin A (Retinol) und Retinolbindendes-Protein (RBP) im Serum bei Maldigestion, Malabsorption und Lebercirrhose

1974

Bei Normalpersonen und Patienten mit Malabsorption, Maldigestion und Lebercirrhose wurden vor und nach oraler Belastung mit 600 000 E Vitamin-A-palmitat bzw. wasserloslichem Vitamin A im Serum der Spiegel des Vitamin A (Retinol), des Retinol-bindenden Proteins (RBP) und Praealbumin bestimmt. In der Kontrolle steigt das Retinol nach Belastung signifikant an und erreicht nach 5 Std sein Maximum. Das RBP liegt im Mittel bei 42,25 mg/L, der Praealbuminspiegel bei 400 mg/L. Patienten mit Malabsorption und Lebercirrhose zeigen vor und nach Belastung mit Vitamin-A-palmitat einen gegenuber der Kontrolle verminderten Retinolspiegel. In der Gruppe der Maldigestion ist der Nuchternspiegel des Retinols…

Gynecologymedicine.medical_specialtybusiness.industryCrohn diseaseRetinolVitamin A RetinolGeneral Medicinechemistry.chemical_compoundchemistryDrug DiscoveryMolecular MedicineMedicineMalabsorption syndromesbusinessRetinol bindingGenetics (clinical)Klinische Wochenschrift
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Biochemical, morphological, and functional aspects of systemic and local vitamin A deficiency in the respiratory tract.

1992

HyperplasiaMucous Membranebusiness.industryVitamin A DeficiencyGeneral NeuroscienceGuinea PigsRespiratory SystemVital CapacityPhysiologymedicine.diseaseGeneral Biochemistry Genetics and Molecular BiologyVitamin A deficiencymedicine.anatomical_structureHistory and Philosophy of ScienceReference ValuesForced Expiratory VolumeMedicineAnimalsHumansCiliabusinessVitamin ARespiratory tractAnnals of the New York Academy of Sciences
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The stellate cell (Ito-cell, fat-storing cell, lipocyte, perisinusoidal cell) of the liver. New insights into pathophysiology of an intriguing cell.

1992

Liver CirrhosisCell divisionChemistryCellPathophysiologyCell biologymedicine.anatomical_structureGene Expression RegulationLiverProtein BiosynthesismedicineFat storing cellHepatic stellate cellAnimalsHumansVitamin AVirchows Archiv. B, Cell pathology including molecular pathology
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The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control st…

2015

Background Abdominal obesity (AO) is a common modifiable risk factor for certain non-communicable diseases associated with enhanced oxidative stress (OS). The objective of this work was to investigate whether the interaction between antioxidant vitamin intake and OS-related polymorphisms modulates gene-associated anthropometry in a Spanish population. Methods A total of 246 subjects with AO, and 492 age and gender matched non-AO subjects were included in the study. Anthropometric, biochemical, and OS parameters, and antioxidant dietary intake data were assessed using validated procedures. DNA from white blood cells was isolated and the genotype of seven polymorphisms from genes involved in …

MaleAntioxidantPolimorphismmedicine.medical_treatment:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Thioredoxins [Medical Subject Headings]Antioxidantes:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]AntioxidantsVitamin E intakeObesidad abdominalchemistry.chemical_compoundNutrigenomicsThioredoxinsPolymorphism (computer science):Anatomy::Cells::Blood Cells::Leukocytes [Medical Subject Headings]Risk FactorsGenotypeVitamin E:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleosides::Deoxyribonucleosides::Deoxyguanosine [Medical Subject Headings]:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::Micronutrients::Vitamins [Medical Subject Headings]:Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress [Medical Subject Headings]Abdominal obesityNutrigenómicaMedicine(all)AnthropometryAge FactorsGeneral MedicineAbdominal obesity:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity::Obesity Abdominal [Medical Subject Headings]Middle Aged:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Logistic Models [Medical Subject Headings]Waist circumferenceDietaFemale:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]medicine.symptomFactores de riesgoVitaminAdultmedicine.medical_specialtyGenotypeVitamina ECatechol-O-methyltransferaseBiology:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes Reporter [Medical Subject Headings]Catechol O-Methyltransferase:Chemicals and Drugs::Biological Factors::Pigments Biological::Carotenoids::Retinoids::Vitamin A [Medical Subject Headings]Polymorphism Single NucleotideGeneral Biochemistry Genetics and Molecular BiologySex FactorsInternal medicine:Chemicals and Drugs::Inorganic Chemicals::Oxygen Compounds::Reactive Oxygen Species [Medical Subject Headings]:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Protective Agents::Antioxidants [Medical Subject Headings]medicinePerímetro abdominal:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Waist Circumference [Medical Subject Headings]:Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds 2-Ring::Benzopyrans::Vitamin E [Medical Subject Headings]HumansObesityPolymorphismThioredoxinAgedCatechol-O-methyl transferaseBiochemistry Genetics and Molecular Biology(all)Vitamin EResearchCase-control studyGenes informadores:Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics::Nutrigenomics [Medical Subject Headings]DietOxidative StressEndocrinologychemistrySpainOxidative stressCase-Control Studies:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::One-Carbon Group Transferases::Methyltransferases::Catechol O-Methyltransferase [Medical Subject Headings]:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings]Genotipo
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Antimutagenic effects and possible mechanisms of action of vitamins and related compounds against genotoxic heterocyclic amines from cooked food.

1999

Possible antimutagenic activity of 26 vitamins and related compounds - ascorbic acid, beta-carotene, cyanocobalamin, folic acid, nicotinic acid, nicotinamide, pantothenic acid, pyridoxale, pyridoxamine, pyridoxine, retinal, retinol, retinoic acid, retinyl acetate, retinyl palmitate, riboflavin, riboflavin 5'-phosphate, flavin adenine dinucleotide (FAD), alpha-tocopherol, alpha-tocopherol acetate, vitamins K(1), K(3), K(4), 1, 4-naphthoquinone, and coenzyme Q(10) - was tested against six heterocyclic amine (HCA) mutagens, i.e., 2-amino-3-methyl-imidazo[4, 5-f]quinoline (IQ), 2-amino-3,4-dimethyl-imidazo[4,5-f]quinoline (MeIQ), 2-amino-3,8-dimethyl-imidazo[4,5-f]quinoxaline (MeIQx), 2-amino-1…

MaleSalmonella typhimuriumHot TemperatureVitamin KHealth Toxicology and MutagenesisRiboflavinFood ContaminationRetinyl acetateIn Vitro TechniquesRats Sprague-Dawleychemistry.chemical_compoundMenadioneRetinyl palmitateGeneticsAnimalsVitamin ABiotransformationFlavin adenine dinucleotidechemistry.chemical_classificationNicotinamideMutagenicity TestsAntimutagenic AgentsVitaminsAscorbic acidRatschemistryBiochemistryHeterocyclic amineFlavin-Adenine DinucleotideMicrosomes LiverQuinolinesFood AnalysisMutagensMutation research
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