Search results for "Volt"

showing 10 items of 2187 documents

Novel σ1 antagonists designed for tumor therapy: Structure – activity relationships of aminoethyl substituted cyclohexanes

2021

Abstract Depending on the substitution pattern and stereochemistry, 1,3-dioxanes 1 with an aminoethyl moiety in 4-position represent potent σ1 receptor antagonists. In order to increase the stability, a cyclohexane ring first replaced the acetalic 1, 3-dioxane ring of 1. A large set of aminoethyl substituted cyclohexane derivatives was prepared in a six-step synthesis. All enantiomers and diastereomers were separated by chiral HPLC at the stage of the primary alcohol 7, and their absolute configuration was determined by CD spectroscopy. Neither the relative nor the absolute configuration had a large impact on the σ1 affinity. The highest σ1 affinity was found for cis-configured benzylamines…

DU145 tumor cellsCachannelPrimary alcohol01 natural sciencesAminoethylcyclohexanes; Antagonistic activity; Biotransformation; Ca; 2+; influx assay; Calculated free energy of binding; CD spectroscopy; Chiral HPLC; DU145 tumor cells; Inhibition of human prostate tumor cell growth; Lipophilicity; Molecular dynamics simulations; Molecular interactions; per-residue binding free energy; Selectivity; Stereochemistry; Structure affinity relationships; Voltage gated Ca; 2+; channel; σ receptors; σ; 1; receptor affinityInhibition of human prostate tumor cell growthStereochemistryDrug DiscoveryMoietySelectivityBiotransformationσ receptor0303 health sciencesChemistryAminoethylcyclohexanesCD spectroscopyAbsolute configurationAminoethylcyclohexaneMolecular interactionGeneral MedicineAntagonistic activityper-residue binding free energyreceptor affinityLipophilicityVoltage gated CaStereochemistry12+Calculated free energy of bindingRetinal ganglion03 medical and health sciencesσMolecular dynamics simulationChiral HPLCLipophilicityMolecular interactionsStructure affinity relationship030304 developmental biologyPharmacologyDU145 tumor cellinflux assayMolecular dynamics simulations010405 organic chemistryOrganic ChemistryDiastereomer0104 chemical sciencesChiral column chromatographyσ receptorsStructure affinity relationshipsEnantiomerEuropean Journal of Medicinal Chemistry
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Role of photoactive layer morphology in high fill factor all-polymer bulk heterojunction solar cells

2011

We report on the realization of all-polymer solar cells based on blends of poly(3-hexylthiophene-2,5-diyl) (P3HT) as a donor and poly{[N,N'-bis(2-octyldodecyl)-naphthalene-1,4,5,8-bis(dicarboximide)-2,6-diyl]-alt-5,5'-(2,2'-bithiophene)} (P(NDI2OD-T2)) as an acceptor. High fill factors are demonstrated for the first time in this class of devices suggesting high dissociation efficiency for the bounded electron-hole pairs and balanced electron and hole mobility along the thin films. The use of the high-mobility n-type P(NDI2OD-T2) polymer enables us to overcome one of the problems limiting the efficiency of all-polymer solar cells, resulting in fill factors comparable with those reported for …

DYNAMICSElectron mobilityMaterials scienceFullerenePHOTOVOLTAIC DEVICESLIGHT-INTENSITY DEPENDENCEBLENDSPolymer solar cellPhotoactive layerMaterials ChemistryThin filmSettore CHIM/02 - Chimica FisicaOpen-circuit voltagebusiness.industryORIGINPOLY(3-HEXYLTHIOPHENE)General ChemistryHybrid solar cellAcceptorTRANSPORTOPEN-CIRCUIT VOLTAGEsolar cells bulk heterojunctions devices organic electronicsTRANSISTORSOptoelectronicsbusinessCONJUGATED POLYMERS
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Switching times in long-overlap Josephson junctions subject to thermal fluctuations and non-Gaussian noise sources

2014

We investigate the superconducting lifetime of long current-biased Josephson junctions, in the presence of Gaussian and non-Gaussian noise sources. In particular, we analyze the dynamics of a Josephson junction as a function of the noise signal intensity, for different values of the parameters of the system and external driving currents. We find that the mean lifetime of the superconductive state is characterized by nonmonotonic behavior as a function of noise intensity, driving frequency and junction length. We observe that these nonmonotonic behaviours are connected with the dynamics of the junction phase string during the switching towards the resistive state. An important role is played…

DYNAMICSJosephson effectKRAMERS PROBLEMPhase (waves)Thermal fluctuationsFOS: Physical sciencesNoise processes and phenomenaSettore FIS/03 - Fisica Della MateriaPi Josephson junctionSuperconductivity (cond-mat.supr-con)symbols.namesakeLEVY FLIGHTSCALING LAWSCondensed Matter::SuperconductivityMesoscale and Nanoscale Physics (cond-mat.mes-hall)Stochastic analysis methodFluctuation phenomenaANOMALOUS DIFFUSIONENHANCED STABILITYSuperconductivityPhysicsRESONANT ACTIVATIONCondensed Matter - Mesoscale and Nanoscale PhysicsCondensed matter physicsNoise (signal processing)Condensed Matter - SuperconductivityBiasingJosephson deviceCondensed Matter PhysicsElectronic Optical and Magnetic MaterialsZERO-VOLTAGE STATEGaussian noisesymbolsZERO-VOLTAGE STATE; ALPHA-STABLE NOISE; RESONANT ACTIVATION; LEVY FLIGHT; ANOMALOUS DIFFUSION; ENHANCED STABILITY; KRAMERS PROBLEM; SCALING LAWS; DYNAMICS; BEHAVIORALPHA-STABLE NOISEBEHAVIOR
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Environmental Data Processing by Clustering Methods for Energy Forecast and Planning

2011

This paper presents a statistical approach based on the k-means clustering technique to manage environmental sampled data to evaluate and to forecast of the energy deliverable by different renewable sources in a given site. In particular, wind speed and solar irradiance sampled data are studied in association to the energy capability of a wind generator and a photovoltaic (PV) plant, respectively. The proposed method allows the sub-sets of useful data, describing the energy capability of a site, to be extracted from a set of experimental observations belonging the considered site. The data collection is performed in Sicily, in the south of Italy, as case study. As far as the wind generation…

Data processingWind powerRenewable Energy Sustainability and the Environmentbusiness.industryComputer sciencePhotovoltaic systemcomputer.software_genreWind speedRenewable energyWind energy; Photovoltaic energy; Distributed generation; Statistical methods; Data processing; ClusteringDistributed generationData miningCluster analysisbusinessTelecommunicationscomputerEnergy (signal processing)
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The new course of FITs mechanism for PV systems in Italy: novelties, strong points and criticalities

2011

The paper deals with the new course of the Feed-in Tariffs mechanism for photovoltaic systems that will start from January 1, 2011 in Italy with the actuation of the Government Decree DM 06/08/2010. After a short introduction on Feed-in Tariffs and Net-metering in Italy, the paper focuses the attention on an economical comparison between the incentives established by the Government Decree DM 19/02/07, ended on December 31, 2010 and those introduced by the DM 06/08/2010. The economical comparison is based on three indexes: the Pay Back Period, the Net Present Value and the Internal Rate of Return, characterizing the investments done for the realization of the photovoltaic systems. In particu…

DecreeGovernmentEngineeringPayback periodPresent valuebusiness.industryPhotovoltaic systemInternal rate of returnSettore ING-IND/33 - Sistemi Elettrici Per L'EnergiaIncentiveEconomyRenewable Energy Resources PV systems Feed-in Tariffs PBP NPV IRR.Feed-in tariffbusinessIndustrial organization
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Impact of Demand Response Control Logic on Isolated Island's Distribution Networks

2019

The work presents the results of a study regarding the impact of some Demand Response control logics on an isolated distribution network. The proposed control is divided into precise steps in which the coordination between the general aggregator controller and the single local Energy Management Systems is developed and illustrated with details. The control is applied to the flexible loads and to the storage systems of photovoltaic plants installed at the end-users' houses and connected to the network. The study is carried out delivering a suitable network model of the island's system, with the implementation of load profiles for all the loads of the network for a total simulation time of 24…

Demand responseelectric storageComputer scienceEnergy managementPhotovoltaic systemControl (management)demand response; EES; electric storage; flexible loads; load aggregation; photovoltaic; PV; small islandsflexible loadsload aggregationControl engineeringPVcomputer.software_genresmall islandsEESNews aggregatorphotovoltaicSettore ING-IND/33 - Sistemi Elettrici Per L'EnergiaDemand responseflexible loadControl theoryControl logiccomputerNetwork model2019 IEEE 5th International forum on Research and Technology for Society and Industry (RTSI)
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Effects of Demand Side Management on the Operation of an Isolated LV Microgrids

2019

The work presents the results of a study regarding the impact of Demand Side Management actions on flexible loads distributed at the domestic end-users' facilities in an isolated low voltage microgrid. Aim of the research study is to evaluate how the implementation of local control actions on the end-user's side can impact on the operation of the isolated microgrid. The Demand Side Management is applied by each domestic user to optimize the operation of its own resources following well-defined operative steps. The study is carried out implementing a suitable model of the microgrid in Neplan environment, while the daily controlled load profiles of the end-users are evaluated using the Montec…

Demand-side managementstorage systemsDemand sideComputer sciencemicrogrids020209 energyPhotovoltaic systemControl (management)flexible loads02 engineering and technologyReliability engineeringSettore ING-IND/33 - Sistemi Elettrici Per L'Energiaphotovoltaicmicrogridflexible load020401 chemical engineeringWork (electrical)0202 electrical engineering electronic engineering information engineeringMicrogrid0204 chemical engineeringMATLABLow voltagecomputerDemand-side management; flexible loads; microgrids; photovoltaic; storage systemscomputer.programming_language2019 IEEE International Conference on Environment and Electrical Engineering and 2019 IEEE Industrial and Commercial Power Systems Europe (EEEIC / I&CPS Europe)
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Fast redox-triggered shuttling motions in a copper rotaxane based on a phenanthroline–terpyridine conjugate

2014

Fast shuttling motions in solution have been observed by cyclic voltammetry in a Cu(I/II)-based [2] rotaxane. In the reported system, the different coordination preferences of both copper oxidation states are exploited to promote the electrochemically-triggered gliding of the ring from a tetra to a pentacoordinated site and vice versa. The thread of this rotaxane consists of a tridentate 2,2':6',2''-terpyridine chelating unit directly bonded through its 5-position to the 3-position of the bidentate 1,10-phenanthroline unit. This distribution reduces to a minimum the distance between the two coordination sites and lessens the congestion around the tetrahedral environment. These two factors h…

DenticityRotaxaneRotaxanesPyridinesPhenanthrolineOrganic Chemistrychemistry.chemical_elementPhotochemistryElectrochemistryBiochemistryRedoxCopperKineticsMotionchemistry.chemical_compoundchemistryElectrochemistryPhysical and Theoretical ChemistryTerpyridineCyclic voltammetryOxidation-ReductionCopperPhenanthrolinesOrg. Biomol. Chem.
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Life Cycle Assessment of a compact Desiccant Evaporative Cooling system: The case study of the “Freescoo”

2016

Abstract The paper aims at exploring the performances of a compact Desiccant Evaporative Cooling system called “Freescoo” (Free Solar Cooling) in comparison to standard conventional technologies. The Freescoo – that aims at applications in the residential sector and in small office buildings and includes a photovoltaic–thermal system – is analyzed, its monitored performance discussed and reported: under cooling conditions an Energy Efficiency Ratio of 12.8 is calculated, that reaches 50.7 if also photovoltaic generation is considered. To assess the performance of the proposed system a Life Cycle Assessment study was performed to investigate the system covering all its life, from the product…

DesiccantSettore ING-IND/11 - Fisica Tecnica AmbientaleRenewable Energy Sustainability and the Environmentbusiness.industry020209 energyPhotovoltaic system02 engineering and technologyLife Cycle AssessmentEnvironmentSolar energySeasonal energy efficiency ratioSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsSolar air conditioningSolar energySustainabilityDEC system0202 electrical engineering electronic engineering information engineeringEnvironmental sciencebusinessProcess engineeringLife-cycle assessmentWater useEvaporative coolerSolar Energy Materials and Solar Cells
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Silver based sensors from CD for chloride ions detection

2021

This preliminary work shows a new and innovative way to produce silver based electrodes from compact discs and its application towards the detection of chloride ions. A complete sensor was obtained from the compact discs with working, reference and counter electrode made of silver. Chloride ions were detected by exploiting the high affinity of silver with this anion to produce silver chloride. This electrochemical oxidation of silver can be monitored by using an electrochemical technique such as linear scan voltammetry. Indeed, during linear scan voltammetry the oxidation of silver to silver chloride lead to a peak current that increases linearly with chloride concentration. Using this tech…

Detection limitAuxiliary electrodevoltammetryMaterials scienceInorganic chemistrycircular economyelectrochemical sensorElectrochemistryChloride ions electrochemical sensor voltammetry circular economyChlorideIonSilver chloridechemistry.chemical_compoundchemistryElectrodemedicineChloride ionsVoltammetrymedicine.drug
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