Search results for "Volume concentration"

showing 10 items of 43 documents

Pathologies currently identified by exhaled biomarkers.

2013

Ancient Greek physicians already knew that the smell of human breath could provide a clue to the pathology. Nowadays, volatile breath biomarkers are known to be released in a broad range of diseases. However, their identification, isolation, and quantification as indicative of relevant alterations in clinical status have required the development of new techniques and analytical methods. Breath sample analysis encounters several obstacles. Particularly, there is a need of a system that could work in a continuous manner, with the low concentration and small volume of a sample. Herein we review, in the light of literature and our experience, clinical applications of the metal oxide semiconduct…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyPathologyVolatile Organic CompoundsIsolation (health care)Physiologybusiness.industrySmall volumeGeneral NeuroscienceDiseasemedicine.diseaseOxide semiconductorBreath gas analysisBreath TestsMedicineHumansbusinessIntensive care medicineMultiple chemical sensitivityVolume concentrationBiomarkersRespiratory physiologyneurobiology
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Dual role of epoxide hydratase in both activation and inactivation of benzo(a)pyrene.

1977

The effect of epoxide hydratase upon the mutagenicity of benzo(a)pyrene was investigated using two Salmonella typhimurium strains (TA 1537 and TA 98). These two bacterial strains were found to differ characteristically in their susceptibility to different mutagens biologically produced from benzo(a)pyrene providing a diagnostic tool to investigate which types of mutagenic metabolites were produced in various metabolic situations. The results showed that the pattern of mutagenic metabolites produced by microsomes from methylcholanthrene-treated mice was very different from that produced by microsomes from phenobarbital-treated or untreated mice. However in all cases at least two mutagenic me…

Salmonella typhimuriumendocrine systemHealth Toxicology and MutagenesisPharmacology toxicologyToxicologychemistry.chemical_compoundMiceDual roleEpoxide HydrataseAnimalsBenzopyrenesVolume concentrationBiotransformationEpoxide Hydrolasesfood and beveragesGeneral MedicineMonooxygenasechemistryBiochemistryBenzo(a)pyrenePhenobarbitalMutationMicrosomeMicrosomes LiverPyreneMethylcholanthreneMutagensArchives of toxicology
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Determination of thallium in water samples

2007

Abstract This article illustrates the developments of effective preconcentration techniques and highly sensitive detection methods for accurate measurements of Tl species at extremely low concentration in aqueous solutions. The literature on this topic was taken from the Analytical Abstracts in the period 1990–2005.

SpeciationChromatographyAqueous solutionchemistryEnvironmental chemistrymedia_common.quotation_subjectThalliumchemistry.chemical_elementSpectroscopyVolume concentrationAnalytical ChemistryHighly sensitivemedia_commonMicrochemical Journal
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Does low concentration mycotoxin exposure induce toxicity in HepG2 cells through oxidative stress?

2020

The purpose of this study was to determine whether exposure to low concentrations of deoxynivalenol (DON), T-2 toxin (T-2) and patulin (PAT) in a human hepatocellular carcinoma cell line (HepG2) exerts toxic effects through mechanisms related to oxidative stress, and how cells deal with such exposure. Cell viability was determined by the MTT and protein content (PC) assays over 24, 48 and 72 h. The IC

Time FactorsCell SurvivalHealth Toxicology and MutagenesisMitochondria LiverHepatic carcinoma010501 environmental sciencesToxicologymedicine.disease_cause01 natural sciencesPatulinInhibitory Concentration 5003 medical and health scienceschemistry.chemical_compoundmedicineHumansMycotoxinVolume concentration0105 earth and related environmental sciencesMembrane Potential Mitochondrial0303 health sciencesDose-Response Relationship DrugToxinChemistry030302 biochemistry & molecular biologyfood and beveragesHep G2 CellsMycotoxinsMolecular biologydigestive system diseasesOxidative StressT-2 ToxinPatulinHepg2 cellsToxicityHepatocytesLipid PeroxidationReactive Oxygen SpeciesTrichothecenesOxidative stressToxicology Mechanisms and Methods
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Fast blue B functionalized silica-polymer composite to evaluate 3,5-dihy-droxyhydrocinnamic acid as biomarker of gluten intake

2021

Celiac disease is an immune-mediated systemic disorder elicited by gluten and related prolamines in genetically susceptible individuals. The current treatment is a strict and lifelong gluten-free diet. However, compliance with the gluten-free diet is not always adequate and many food products contain low concentrations of gluten. The determination of dietary transgressions is a challenge for patients, physicians and dietitians. Alkylresorcinols (AR) have been proposed as sensitive and specific biomarkers of gluten consumption. In this work silica-polymer composites doped with fast blue B reagent (FB) have been used to estimate alkylresorcinols in biological samples. The proposed colorimetri…

alkylresorcinols02 engineering and technology010402 general chemistry01 natural sciencesfast blue BMaterials ChemistryElectrical and Electronic EngineeringInstrumentationFast blueVolume concentrationchemistry.chemical_classificationChromatographyMetals and AlloysbiomarkersGluten intake021001 nanoscience & nanotechnologyCondensed Matter PhysicsGlutencapillary liquid chromatography0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryReagentFood productsPDMS compositesPolymer compositesBiomarker (medicine)0210 nano-technologyceliac disease
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Coumarin derivatives from Pedilanthus tithymaloides as inhibitors of conidial germination in Magnaporthe oryzae

2012

In a screening for inhibitors of infection-related morphogenesis in the rice blast fungus Magnaporthe oryzae, a series of 10 coumarin derivatives were isolated from Pedilanthus tithymaloides (Euphorbiaceae). Seven of these compounds turned out to be known while three represent previously unreported natural products. Their structures were established on the basis of spectroscopic data and X-ray crystallography. Nine out of 10 coumarin derivatives were found to inhibit conidial germination in the phytopathogenic fungus at low concentrations.

biologyPedilanthus tithymaloidesChemistryOrganic ChemistryEuphorbiaceaeFungusbiology.organism_classificationCoumarinBiochemistryMagnaporthe oryzaechemistry.chemical_compoundBiochemistryGerminationDrug Discoveryheterocyclic compoundsVolume concentrationTetrahedron Letters
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Die Beschleunigung der Polymerisation durch Hydroperoxyd und Aminsalz

1964

Di-n-butylaminhydrochlorid vergrosert die Geschwindigkeit der durch Tetralinhydroperoxyd initiierten Polymerisation von Styrol und von Methylmethacrylat. Im Bereich kleiner Konzentrationen von Hydroperoxyd und Aminsalz bis zu je etwa 5·10−4 Mol/l ist die Reaktionsgeschwindigkeit der Wurzel aus der Hydroperoxyd- und Aminsalzkonzentration jedoch der Monomerkonzentration direkt proportional. The polymerisation rate of styrene and methylmethacrylate initiated by tetraline hydroperoxide is accelerated by di-n-butylamine hydrochloride. In the range of low concentrations up to 5 · 10−4 mole/l. of each, hydroperoxide and amine salt, the rate of polymerisation is proportional to the square roote of …

chemistry.chemical_compoundMonomerPolymerizationchemistryHydrochloridePolymer chemistryAmine gas treatingVolume concentrationStyreneDie Makromolekulare Chemie
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Partielle spezifische volumina von m.m′-ditolyl und seinen oligomeren

1969

Das partielle spezifische Volumen von m.m′-Ditolyl in Toluol wurde durch Dichtemessungen uber den gesamten Konzentrationsbereich bei 25°C bestimmt. Das hieraus berechnete molare Uberschusvolumen betragt −0,21 cm3/Mol bei einem Volumenbruch von 0,5. Die partiellen spezifischen Volumina von Oligomeren des m.m′-Ditolyls wurden in einem niedrigen Konzentrationsbereich in Toluol, Benzol und Trichlorathylen bei 25°C bestimmt. Sie sind in erster Naherung dem Molekulargewicht umgekehrt proportional. The partial specific volume of m.m′-ditolyl in toluene was determined by means of density measurement over the entire range of concentrations at 25°C. The molar excess volume computed hereof turns out t…

chemistry.chemical_compoundchemistryPartial specific volumePolymer chemistryTolueneMedicinal chemistryVolume concentrationDie Makromolekulare Chemie
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Novel supramolecular affinity materials based on (−)-isosteviol as molecular templates

2013

The readily available ex-chiral-pool building block (−)-isosteviol was combined with the C3-symmetric platforms hexahydroxytriphenylene and hexaaminotriptycene providing large and rigid molecular architectures. Because of the persistent cavities these scaffolds are very potent supramolecular affinity materials for head space analysis by quartz crystal microbalances. The scaffolds serve in particular as templates for tracing air-borne arenes at low concentration. The affinities of the synthesized materials towards different air-borne arenes were determined by 200 MHz quartz crystal microbalances.

inorganic chemicalstemplatesChemistryOrganic Chemistrytechnology industry and agricultureSupramolecular chemistryNanotechnologyaffinity materials(−)-IsosteviolCombinatorial chemistryAffinitiesFull Research Papersupramolecular chemistrytriphenylene ketalslcsh:QD241-441CrystalChemistryTemplatelcsh:Organic chemistrytriptyceneslcsh:Qlcsh:ScienceQuartzVolume concentrationBeilstein Journal of Organic Chemistry
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Tagesprofile von Plasmaaldosteron,-Cortisol, -Renin, -Angiotensinogen und -Angiotensinasen bei Normalpersonen

1976

Plasma cortisol and renin were estimated in 1 h intervals, plasma aldosterone, angiotensinogen and angiotensinases in 3 h intervals over periods of 24 h in six normal volunteers (age 20-26) under control conditions and subsequently under suppression of ACTH release by dexamethasone. Highest cortisol levels were found around 7 a.m., minimum levels between 9 p.m. and 1 a.m. Dexamethasone reduced cortisol to constantly low concentrations. Aldosterone was highest around 4 a.m. under control conditions and under dexamethasone, and showed lowest concentrations between 4 and 10 p.m. There were no significant differences between mean aldosterone concentrations at corresponding time points of the co…

medicine.medical_specialtyAldosteroneGeneral MedicineAdrenocorticotropic hormonechemistry.chemical_compoundEndocrinologychemistryInternal medicineDrug DiscoveryRenin–angiotensin systemmedicineMolecular MedicineCircadian rhythmCortisoneCortisol levelGenetics (clinical)DexamethasoneVolume concentrationmedicine.drugKlinische Wochenschrift
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