Search results for "WESTERN"

showing 10 items of 1138 documents

Overexpression of Human and Fly Frataxins in Drosophila Provokes Deleterious Effects at Biochemical, Physiological and Developmental Levels

2011

10 pages, 5 figures. 21779322[PubMed] PMCID: PMC3136927

Transgeneved/biology.organism_classification_rank.speciesBlotting WesternLongevitylcsh:MedicineMitochondrionMotor ActivityAconitaseAnimals Genetically ModifiedModel OrganismsIron-Binding ProteinsMorphogenesisGeneticsAnimalsHumansModel organismlcsh:ScienceBiologyGeneticsAconitate HydrataseGene knockdownBrain DiseasesMultidisciplinaryMovement Disordersbiologyved/biologyDrosophila Melanogasterfungilcsh:RAnimal Modelsbiology.organism_classificationPhenotypeImmunohistochemistryMitochondriaOxidative StressNeurologyFriedreich AtaxiaGenetics of DiseaseFrataxinbiology.proteinChromatography GelMedicinelcsh:QDrosophilaDrosophila melanogasterResearch ArticleDevelopmental BiologyPLoS ONE
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ROUTES OF HIV-2 TRANSMISSION IN WESTERN EUROPE

1987

Transmission (mechanics)lawbusiness.industryWestern europeHuman immunodeficiency virus (HIV)medicineGeneral MedicineSocioeconomicsmedicine.disease_causebusinesslaw.inventionThe Lancet
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Proteomic profiling of Trastuzumab (Herceptin(R))-sensitive and -resistant SKBR-3 breast cancer cells.

2013

BACKGROUND: The Human Epidermal Growth Factor Receptor 2 (HER-2), overexpressed in 25-30% of breast carcinomas (BC), is the therapeutic target for trastuzumab, a recombinant humanized monoclonal antibody. The initial response to trastuzumab is often followed by drug-insensitivity within one year. Several hypotheses have been raised to explain this event, but the mechanisms behind the responses to trastuzumab are still unclear. Aim: To study the effects of short and prolonged trastuzumab treatment on the proteomic profiles of HER-2-overexpressing SKBR-3 BC cells. MATERIALS AND METHODS: Cells were treated with trastuzumab to obtain sensitive and resistant clones. The drug effects were evaluat…

Trastuzumab Herceptin(R) Breast Cancer ProteomicsBlotting WesternAntineoplastic AgentsBreast NeoplasmsTrastuzumabAntibodies Monoclonal HumanizedMass SpectrometrySettore BIO/13 - Biologia ApplicataDrug Resistance NeoplasmCell Line TumorHumansElectrophoresis Gel Two-DimensionalFemaleSettore BIO/06 - Anatomia Comparata E CitologiaTranscriptomeCell ProliferationAnticancer research
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First Record of Eurasian Spoonbills Platalea leucorodia feeding on Branchiopoda in a temporary wetland

2020

The diet of the Eurasian Spoonbill Platalea leucorodia is poorly documented with only the most common prey groups known, namely small fishes, amphibians, reptiles, crustaceans, molluscs, worms, leeches and plant material. Here, the first observations of three small crustaceans, Branchiopoda Triops cancriformis (Notostraca), Chirocephalus diaphanus (Anostraca), and Cyzicus tetracerus (Spinicaudata) are documented as prey of the Eurasian Spoonbill in a temporary wetland near the San Teodoro salt pan (Marsala, western Sicily). These observations provide a new insight into the foraging ecology of the species, showing its extreme opportunism in targeting small prey when feeding in a temporary we…

Triops Notostraca Anostraca Spinicaudata foraging western Sicily
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Biocénoses à triopsidés(Crustacea, Branchiopoda) du Permien du bassin de Lodève (France)

1997

Resume Nous decrivons les triopsides (Crustacea, Branchiopoda) qui abondent dans les facies “saxoniens” de la Formation du Salagou du bassin de Lodeve date “Thuringien” ou “Saxonien” selon les auteurs. A partir de milliers de debris de carapaces, d'axes thoraco-abdominaux et plus rarement a partir d'animaux entiers, nous avons identifie et decrit deux especes nouvelles: Triops cancriformis permiensis nov. ssp. et Lepidurus occitaniacus nov. sp., morphologiquement proches d' especes actuelles. En se basant sur les preferences ecologiques des triopsides actuels et les caracteristiques sedimentologiques de leur milieu de vie au Permien, nous avons confirme l'existence d'etendues d'eau, peu pro…

TriopsGeographybiologySpace and Planetary ScienceWestern europeMandibulataPaleontologyBiostratigraphybiology.organism_classificationHumanitiesGeobios
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Analysis of p53 and mdm2 proteins in malignant fibrous histiocytoma in absence of gene alteration: prognostic significance.

2000

TP53 and MDM2 genes and their protein expression were evaluated in frozen and paraffin-embedded tissue from 27 patients with malignant fibrous histiocytoma to elucidate the relationship between them, their implication in tumor progression mechanisms and their possible diagnostic-prognostic value in malignant fibrous histiocytoma. Single-strand conformation polymorphism analysis and direct sequencing of polymerase chain reaction-amplified DNA were used to establish two TP53 mutations (7.4%): a point mutation and a 63-bp duplication. Amplification of the MDM2 gene was observed in two tumors (7.4%) by means of Southern-blot analysis, one of them also carrying the TP53 point mutation. Immunohis…

Tumor suppressor geneBlotting WesternSoft Tissue NeoplasmsBiologyPolymerase Chain ReactionPathology and Forensic MedicineImmunoenzyme TechniquesMiceProto-Oncogene ProteinsGene duplicationGene expressionAnimalsHumansneoplasmsMolecular BiologyGeneTP53 Gene MutationPolymorphism Single-Stranded ConformationalCell NucleusMice Inbred BALB CHistiocytoma Benign FibrousPoint mutationNuclear ProteinsSingle-strand conformation polymorphismProto-Oncogene Proteins c-mdm2Cell BiologyGeneral MedicineDNA NeoplasmMolecular biologyNeoplasm ProteinsSurvival RateBlotting SouthernTumor progressionMutationCancer researchNeoplasm Recurrence LocalTumor Suppressor Protein p53Virchows Archiv : an international journal of pathology
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Getting Adapted? A Comparative Study of Qualified Turkish Return Migrants from Germany and the USA

2017

When we consider the international migration history of Turkey, we see the key position of the immigration of worker migrants to Germany that has been going on since the 1960s. Due to the waves of migration from Turkey to Europe, and especially to Germany, Turks now form one of the largest minority groups living in Western Europe who have migrated from outside of the European Union (EU) region (Sirkeci 2002: 9). As a consequence, beginning from the first period of migration, Turkish migration to Germany has been a subject that social scientists have intensively analyzed. However, most studies have focused on guest workers and there have been a limited number of studies looking at the case o…

Turkishmedia_common.quotation_subject05 social sciencesImmigration0507 social and economic geographyAncient historylanguage.human_language0506 political scienceWestern europePolitical science050602 political science & public administrationlanguagemedia_common.cataloged_instancePosition (finance)Demographic economicsEuropean union050703 geographymedia_common
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Early onset of Type 1 diabetes mellitus in immigrant children from developing countries to Western Europe: The role of environmental factors?

2005

Type 1 diabetesPediatricsmedicine.medical_specialtybusiness.industryEndocrinology Diabetes and Metabolismmedia_common.quotation_subjectImmigrationDeveloping countrymedicine.diseaseEndocrinologyWestern europemedicinebusinessDemographymedia_commonEarly onsetJournal of Endocrinological Investigation
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OVERTURE Love Love is a Pink Cake or Queering Chopin in Times of Homophobia

2021

An introduction to the three essays included in this section. The article highlights the right to know whether Chopin was gay and contextualizes this inquiry in a very long and pervasive historiographical tradition, essentially twohundred years long, dedicated to examine Chopin sexual orientation, on the one hand, and on the other the more recent tradition of queering western classical music composers. The main point is not to demonstrate categorically that Chopin was ?gay? (a relative, modern identity marker in any case) but rather to highlight the discourses that have presented him as unequivocally heterosexual.

UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASessentially twohundred years longAntoni An introduction to the three essays included in this section. The article highlights the right to know whether Chopin was gay and contextualizes this inquiry in a very long and pervasive historiographical tradition:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]revista de investigación musical: territorios para el arte 590908 2021 7 8182075 OVERTURE Love Love is a Pink Cake or Queering Chopin in Times of Homophobia Pizàand on the other the more recent tradition of queering western classical music composers. The main point is not to demonstrate categorically that Chopin was ?gay? (a relativeterritorios para el arte 590908 2021 7 8182075 OVERTURE Love Love is a Pink Cake or Queering Chopin in Times of Homophobia Pizà [revista de investigación musical]dedicated to examine Chopin sexual orientation2386-8260 13268 Itamaron the one handmodern identity marker in any case) but rather to highlight the discourses that have presented him as unequivocally heterosexual. 421 427
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La muerte del mito

1990

Habría de ser de nuevo John Ford quien sentenciará la defunción del western en cuanto mito, su imposibilidad de construirse en el vacío de la historia. Y habría de ser en uno de los más lúcidos films de la historia del cine: The Man who shot Liberty Valance (El hombre que mató a Liberty Valance, 1962). Todo en este film posee un reverso: un viaje en ferrocarril abre paso al pueblecito de Shinbone. Pero, en el interior del relato, otro emprendido por el antes pionero y hoy estadista Stoddard (James Stewart) nos devuelve a un universo más acorde con el mítico Oeste: pistolas, tiroteos, diligencias, la ley del más fuerte ... En el interior de este mundo, se interpone un hombre que blande la ra…

UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASwestern:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]John FordEl hombre que mató a Liberty ValanceThe Man who shot Liberty Valance
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