Overexpression of Human and Fly Frataxins in Drosophila Provokes Deleterious Effects at Biochemical, Physiological and Developmental Levels

6533b834fe1ef96bd129d7ea

RESEARCH PRODUCT

Overexpression of Human and Fly Frataxins in Drosophila Provokes Deleterious Effects at Biochemical, Physiological and Developmental Levels

M. J. Martínez-sebastián Sirena Soriano Stephan Schneuwly José Vicente Llorens José Vicente Llorens María Dolores Moltó Juan A. Navarro José A. Botella

subject

Transgene ved/biology.organism_classification_rank.species Blotting Western Longevity lcsh:Medicine Mitochondrion Motor Activity Aconitase Animals Genetically Modified Model Organisms Iron-Binding Proteins Morphogenesis Genetics Animals Humans Model organism lcsh:Science Biology Genetics Aconitate Hydratase Gene knockdown Brain Diseases Multidisciplinary Movement Disorders biology ved/biology Drosophila Melanogaster fungi lcsh:R Animal Models biology.organism_classification Phenotype Immunohistochemistry Mitochondria Oxidative Stress Neurology Friedreich Ataxia Genetics of Disease Frataxin biology.protein Chromatography Gel Medicine lcsh:Q Drosophila Drosophila melanogaster Research Article Developmental Biology

description

10 pages, 5 figures. 21779322[PubMed] PMCID: PMC3136927

year	journal	country	edition	language
2011-07-11	PLoS ONE

10.1371/journal.pone.0021017 http://europepmc.org/articles/PMC3136927

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