Search results for "WIDE"
showing 10 items of 1235 documents
A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol
2012
Serum lipid levels have been associated with cardiovascular diseases, metabolic syndrome and type II diabetes (Kannel et al., 1961; Miller & Miller, 1975; Pilia et al., 2006). Variation in lipids levels is highly influenced by heritable factors (Friedlander et al., 1997) and 95 loci have already been associated with levels of high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol, triglycerides (TG) and total cholesterol (TC) in numerous study samples and replicated in various populations using genome-wide approaches (Aulchenko et al., 2008; Kathiresan et al., 2008; Kooner et al., 2008; Teslovich et al., 2010; Willer et al., 2008). However, the genetic associa…
Raman measurements on GaN thin films for PV - purposes
2012
Raman scattering (RS) is a very important experimental tool to characterize the optical modes and another elementary excitations of materials. Among other issues it can determine for example the degree of crystalline quality and point defects like local modes. Therefore GaN - thin films and related compounds for photovoltaic purposes and as processed by several systems have been measured by this technique. The films were grown by Molecular Beam Epitaxy (MBE), Close Spaced Vapor Transport (CSVT) and Laser Ablation (LA) with the use of optimal growth parameters and substrates. Gallium nitride crystallizes in the wurtzite structure with 4 atoms in the unit cell and presents 7 allowed Raman mod…
Influence Assessment in Twitter Multi-relational Network
2015
International audience; Influence in Twitter has become recently a hot research topic since this micro-blogging service is widely used to share and disseminate information. Some users are more able than others to influence and persuade peers. Thus, studying most influential users leads to reach a large-scale information diffusion area, something very useful in marketing or political campaigns. In this paper, we propose a new approach for influence assessment on Twitter network, it is based on a modified version of the conjunctive combination rule in belief functions theory in order to combine different influence markers such as retweets, mentions and replies. We experiment the proposed meth…
GAIML: A New Language for Verbal and Graphical Interaction in Chatbots
2008
Natural and intuitive interaction between users and complex systems is a crucial research topic in human-computer interaction. A major direction is the definition and implementation of systems with natural language understanding capabilities. The interaction in natural language is often performed by means of systems called chatbots. A chatbot is a conversational agent with a proper knowledge base able to interact with users. Chatbots appearance can be very sophisticated with 3D avatars and speech processing modules. However the interaction between the system and the user is only performed through textual areas for inputs and replies. An interaction able to add to natural language also graph…
Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder
2010
Contains fulltext : 87688.pdf (Publisher’s version ) (Closed access) OBJECTIVE: Although twin and family studies have shown attention-deficit/hyperactivity disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome-wide significant level have yet to be identified. As prior genome-wide association studies (GWAS) have not yielded significant results, we conducted a meta-analysis of existing studies to boost statistical power. METHOD: We used data from four projects: a) the Children's Hospital of Philadelphia (CHOP); b) phase I of the International Multicenter ADHD Genetics project (IMAGE); c) phase II of IMAGE (IMAGE II); and d) the Pfizer-funded study from the…
Predictive and Evolutive Cross-Referencing for Web Textual Sources
2017
International audience; One of the main challenges in the domain of competitive intelligence is to harness important volumes of information from the web, and extract the most valuable pieces of information. As the amount of information available on the web grows rapidly and is very heterogeneous, this process becomes overwhelming for experts. To leverage this challenge, this paper presents a vision for a novel process that performs cross-referencing at web scale. This process uses a focused crawler and a semantic-based classifier to cross-reference textual items without expert intervention, based on Big Data and Semantic Web technologies. The system is described thoroughly, and interests of…
Biofilm formation of listeria monocytogenes strains under food processing environments and pan-genome-wide association study
2019
International audience; Concerns about food contamination by Listeria monocytogenes are on the rise with increasing consumption of ready-to-eat foods. Biofilm production of L. monocytogenes is presumed to be one of the ways that confer its increased resistance and persistence in the food chain. In this study, a collection of isolates from foods and food processing environments (FPEs) representing persistent, prevalent, and rarely detected genotypes was evaluated for biofilm forming capacities including adhesion and sessile biomass production under diverse environmental conditions. The quantity of sessile biomass varied according to growth conditions, lineage, serotype as well as genotype bu…
Genome-wide association study identifies five loci associated with lung function
2009
Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory volume in 1 s (FEV(1)) and the ratio of FEV(1) to forced vital capacity (FVC) in the SpiroMeta consortium (n = 20,288 individuals of European ancestry). We conducted a meta-analysis of top signals with data from direct genotyping (n < or = 32,184 additional individuals) and in silico summary association data from the CHARGE Consortium (n = 21,209) and the Health 2000 survey (n < or = 883). We confirmed the reported locus at 4q31 and identified associations with FEV(1) or FEV(1)/FVC and co…
From technology engineering to social engineering
2007
Virtual worlds have a long history, and it also includes various technologies. Yet research interest towards them has diverged over the years. It seems that nowadays they are on focus again with the evolution of socially oriented and community-supporting virtual worlds. Instead of technical factors, human factors and the motivation behind the use are highlighted. In this paper, we will briefly review the research efforts made in the 90's, and derive a set of themes that were of interest back then. Next, we will expand the set by arguing for newer themes, identified in the latest information systems literature. These two sets of themes form a basis of a research agenda for studying virtual w…
INFORMATION QUALITY PROBLEMS ON WEBSITES
2019
The goal of this publication is to identify and characterize the typical problems with information quality on websites, and to present exemplary remedies for those problems. In this article the information quality problems within their origins, as well as the consequences of using poor-quality information by the Internet user were defined. There were also presented ways of improving information quality - which should facilitate the information needed by producers/authors and the managers/administrators of services in or to find solutions to the remaining problems. The presented varied remedies are not all possible solutions to improving quality in the area of the WWW content and its infrast…