Search results for "WTH"
showing 10 items of 5145 documents
Are Intercultural Competences at the Center of Job-Market Demands ?
2020
International audience; This chapter introduces the theoretical framework upon which this study was based before going on to set out the methodology used and detail the main results found. It discusses results in the light of scientific literature on the issue and their managerial implications. With the internationalization of organizational structures, the development of intercultural competences was often considered a strategic benefit. Indeed, companies are sensitive to the cultural diversity of their worldwide branches and to the international competences developed by their employees. Through organizational internationalization, intercultural competences become strategic resources. Alth…
The 2017 PREDICT Key Facts Report: An Analysis of ICT R&D in the EU
2017
The 2017 PREDICT Key Facts Report provides a detailed analysis of the state of ICT R&D activities in the European Union. This is the tenth edition of a series that is published annually. Like the previous editions, an online version is available at: https://ec.europa.eu/jrc/en/predict. The PREDICT dataset 2017 is based on the latest data available from official sources (such as the Eurostat and OECD, National Accounts and R&D statistics). It also includes the novelty of backwards reconstruction of the series from 1995, which allows it to cover the period from 1995 to 2014. Therefore, it provides a long-term analysis of the EU ICT sector and its R&D, covering a whole cycle since the initial …
Ús del programa Berkeley Madonna per al desenvolupament de models en la docència en Enginyeria Química
2014
La modelització és un procediment metodològic fonamental per a resoldre problemes en enginyeria. Consisteix en representar el problema d'una forma adequada, de manera que s'aconsegueixi una substitució del sistema real per altre més adequat que permeti el tractament formal. És per això que el seu aprenentatge és molt important en l'estudi de l'Enginyeria Química i s'emmarca en les competències contingudes en el mòdul de tecnologia específica, Química Industrial (Ordre CIN/351/2009). En el present treball, es proposa l'ús del programa informàtic Berkeley Madonna per a l'estudi de la modelització del creixement bacterià sobre un o diversos substrats en l'assignatura Processos Biotecnològics d…
Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the a…
2015
Chronic alcohol exposure reduces endocannabinoid activity and disrupts adult neurogenesis in rodents, which results in structural and functional alterations. Cannabinoid receptor agonists promote adult neural progenitor cell (NPC) proliferation. We evaluated the protective effects of the selective CB1 receptor agonist ACEA, the selective CB2 receptor agonist JWH133 and the fatty-acid amide-hydrolase (FAAH) inhibitor URB597, which enhances endocannabinoid receptor activity, on NPC proliferation in rats with forced consumption of ethanol (10%) or sucrose liquid diets for 2 weeks. We performed immunohistochemical and stereological analyses of cells expressing the mitotic phosphorylation of his…
Comparative Analysis of Machine Learning Methods to Predict Growth of F. sporotrichioides and Production of T-2 and HT-2 Toxins in Treatments with Et…
2021
The efficacy of ethylene-vinyl alcohol copolymer films (EVOH) incorporating the essential oil components cinnamaldehyde (CINHO), citral (CIT), isoeugenol (IEG), or linalool (LIN) to control growth rate (GR) and production of T-2 and HT-2 toxins by Fusarium sporotrichioides cultured on oat grains under different temperature (28, 20, and 15 °C) and water activity (aw) (0.99 and 0.96) regimes was assayed. GR in controls/treatments usually increased with increasing temperature, regardless of aw, but no significant differences concerning aw were found. Toxin production decreased with increasing temperature. The effectiveness of films to control fungal GR and toxin production was as follows: EVOH…
Surface plasmon resonance signal enhancement based on erlotinib loaded magnetic nanoparticles for evaluation of its interaction with human lung cance…
2021
Abstract Surface plasmon resonance (SPR) sensor provides a very useful tool based on its label-free, real-time monitoring and low price properties. However, measurement of small molecules and extremely diluted analytes is difficult and therefore, signal enhancement is required. In the present study, signal enhancement of erlotinib conjugated magnetic nanoparticles (erlotinib-MNPs) compared to erlotinib was evaluated via their interaction with overexpressed epidermal growth factor receptor on human lung cancer cells (A549 cell line) surface using SPR sensor at three temperature levels. The attained results showed an average signal amplification of about 2.5-fold for MNP-erlotinib interaction…
Positive effects of an extracellular matrix hydrogel on rat anterior cruciate ligament fibroblast proliferation and collagen mRNA expression
2015
Summary Background/Objective We have previously shown that an extracellular matrix (ECM) bioscaffold derived from porcine small intestine submucosa (SIS) enhanced the healing of a gap injury of the medial collateral ligament as well as the central third defect of the patellar tendon. With the addition of a hydrogel form of SIS, we found that a transected goat anterior cruciate ligament (ACL) could also be healed. The result begs the research question of whether SIS hydrogel has positive effects on ACL fibroblasts (ACLFs) and thus facilitates ACL healing. Methods In the study, ECM-SIS hydrogel was fabricated from the digestion of decellularised and sterilised sheets of SIS derived from αGal-…
Brothers in arms: proBDNF/BDNF and sAPPα/Aβ-signaling and their common interplay with ADAM10, TrkB, p75NTR, sortilin, and sorLA in the progression of…
2021
Abstract Brain-derived neurotrophic factor (BDNF) is an important modulator for a variety of functions in the central nervous system (CNS). A wealth of evidence, such as reduced mRNA and protein level in the brain, cerebrospinal fluid (CSF), and blood samples of Alzheimer’s disease (AD) patients implicates a crucial role of BDNF in the progression of this disease. Especially, processing and subcellular localization of BDNF and its receptors TrkB and p75 are critical determinants for survival and death in neuronal cells. Similarly, the amyloid precursor protein (APP), a key player in Alzheimer’s disease, and its cleavage fragments sAPPα and Aβ are known for their respective roles in neuropro…
The European Regional Convergence Process, 1980-1995: Do Spatial Regimes and Spatial Dependence Matter?
2002
International audience; The authors show that spatial dependence and spatial heterogeneity matter in the estimation of the ß-convergence process among 138 European regions over the 1980 to 1995 period. Using spatial econometrics tools, the authors detect both spatial dependence and spatial heterogeneity in the form of structural instability across spatial convergence clubs. The estimation of the appropriate spatial regimes spatial error model shows that the convergence process is different across regimes. The authors also estimate a strongly significant spatial spillover effect: the average growth rate of per capita GDP of a given region is positively affected by the average growth rate of …
Adolescence Surveillance System for Obesity Prevention (ASSO) in Europe
2017
Adolescents' obesity is a major concern in our modern life that could lead to significant increase in the rate of obese future generations and consequently in the health budget. The ASSO (Adolescence Surveillance System for Obesity prevention) project in Italy is tackling this new pandemic using the new e-technology through a multi facets monitoring system on life style including food consumptions, meal patterns and habits, alcohol, smoking, physical activity, fitness and sedentariness, and biological/genetic, and socio-cultural/environmental characteristics of adolescents. The project has been recently piloted in the South of the country. This chapter summarizes the design and structure of…