Search results for "Well-Being"

showing 10 items of 1190 documents

The Quality of Life among Siblings of Autistic Individuals: A Scoping Review

2023

Autism spectrum disorders are a heterogeneous group of neurodevelopmental disorders presenting at a tender age, defined by qualitative deficits in social interactions and communication, thus having a substantial influence on the subject’s family unit. Quality of life (QoL) refers to a person’s perspective of their life situation, cultural and value background, objectives, expectations, and standards. When focusing on childhood and adolescence, age-related changes should be considered. For this scoping review, the authors used three peer-review literature database sources (PubMed/MEDLINE, Scopus, and ERIC) to delve deeper into components of the QoL of non-autistic siblings of autistic indivi…

General MedicineQoLautism autism spectrum disorders quality of life siblings well-beingJournal of Clinical Medicine
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Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

2018

Background: DNA methylation at the GFI1-locus has been repeatedly associated with exposure to smoking from the foetal period onwards. We explored whether DNA methylation may be a mechanism that links exposure to maternal prenatal smoking with offspring's adult cardio-metabolic health.Methods: We meta-analysed the association between DNA methylation at GFI1-locus with maternal prenatal smoking, adult own smoking, and cardio-metabolic phenotypes in 22 population-based studies from Europe, Australia, and USA (n= 18,212). DNA methylation at the GFI1-locus was measured in whole-blood. Multivariable regression models were fitted to examine its association with exposure to prenatal and own adult s…

Genetics and Molecular Biology (all)MaleNetherlands Twin Register (NTR)0301 basic medicineResearch paperGFI1 protein humanGFI1-locusraskausResearch & Experimental Medicinecardio-metabolic phenotypesBiochemistryEpigenesis GeneticGLOBAL Meth QTL Consortium0302 clinical medicinePregnancySmoke030212 general & internal medicinematernal prenatal smokingDNA METHYLATIONmedia_commonRISK2. Zero hungereducation.field_of_studySmokingta3142General MedicineMiddle Agedgenetics [Transcription Factors]3. Good healthDNA-Binding ProteinsPhenotypeMedicine Research & ExperimentalCARDIOVASCULAR-DISEASEepigenetiikkaPopulation SurveillancePrenatal Exposure Delayed EffectsDNA methylation/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleDisease SusceptibilityBIOS ConsortiumMedical GeneticsLife Sciences & BiomedicineAdultmedicine.medical_specialtyOffspringBirth weightPopulationMothersgenetics [DNA-Binding Proteins]ta3111MethylationGeneral Biochemistry Genetics and Molecular BiologyDIET03 medical and health sciencesMedicine General & InternalSDG 3 - Good Health and Well-beingtupakointiGeneral & Internal MedicineInternal medicine/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_medicinemedia_common.cataloged_instanceHumansddc:610adverse effects [Maternal Exposure]EXPOSUREEpigeneticsEuropean unioneducationMedicinsk genetikEPIGENOME-WIDE ASSOCIATIONPregnancyBiochemistry Genetics and Molecular Biology (all)Science & Technologybusiness.industryadverse effects [Smoking]DNA Methylationta3121medicine.diseaseBIRTH-WEIGHT030104 developmental biologyEndocrinologyGenetic Locisydän- ja verisuonitauditCpG IslandsCIGARETTE-SMOKINGCESSATIONEnergy Metabolismmetabolism [Myocardium]businessBody mass indexBiomarkersTranscription FactorsEBioMedicine
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Factors influencing psychological well-being in patients with Parkinson's disease.

2017

Background Both motor and non-motor symptoms could contribute to significant deterioration of psychological well-being in patients with Parkinson's disease (PD). However, its assessment has been only indirectly evaluated using tools based on health-related quality of life (HRQoL), such as the PDQ-39 scale. Objectives To evaluate psychological well-being in PD using a specific tool of assessment, the Psychological Well-being Scale (PWS), and its clinical correlates. Methods This article reports data of patients' perception of health state, as measured by means of the PWS, from an epidemiological, cross-sectional study conducted in Italian PD patients (FORTE Study). We tested possible relatio…

Genetics and Molecular Biology (all)MaleParkinson's diseaseEmotionsPoison controlSocial Scienceslcsh:MedicinePathology and Laboratory MedicineBiochemistrySeverity of Illness IndexAged; Depression; Fatigue; Female; Humans; Italy; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Scales; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)0302 clinical medicineMathematical and Statistical TechniquesQuality of lifeSurveys and QuestionnairesMedicine and Health SciencesMedicinePsychologySurveys and Questionnaire030212 general & internal medicinelcsh:ScienceDepression (differential diagnoses)FatigueMultidisciplinaryMovement DisordersDepressionNeurodegenerative DiseasesParkinson DiseaseMiddle AgedPsychiatric Status Rating ScalehumanitiesNeurologyItalyPhysical SciencesFemaleStatistics (Mathematics)Clinical psychologyResearch ArticleHumanResearch and Analysis Methods03 medical and health sciencesSigns and SymptomsDiagnostic MedicineSeverity of illnessInjury preventionMental Health and PsychiatryHumansStatistical MethodsAgedPsychiatric Status Rating Scalesparkinson's disease quality of lifeAnalysis of VarianceBiochemistry Genetics and Molecular Biology (all)business.industryMood Disorderslcsh:RBeck Depression InventoryBiology and Life Sciencesmedicine.diseaseHealth CareAgricultural and Biological Sciences (all)Psychological well-beingAged; Depression; Fatigue; Female; Humans; Italy; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Scales; Quality of Life; Severity of Illness Index; Surveys and QuestionnairesQuality of Lifelcsh:QbusinessSleep Disorders030217 neurology & neurosurgeryMathematicsPLoS ONE
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No association between two polymorphisms of the serotonin transporter gene and combined type attention deficit hyperactivity disorder.

2008

Contains fulltext : 71091.pdf (Publisher’s version ) (Closed access) Several independent studies have reported association between serotonin transporter gene (SLC6A4) polymorphisms and attention deficit hyperactivity disorder (ADHD). Five studies found evidence for association between the long-allele of a 44-bp insertion/deletion polymorphism (5-HTTLPR) and ADHD. Another two studies corroborated this finding while a further six studies did not find such an association. For a second polymorphism within the gene, a variable number tandem repeat (VNTR) within intron 2, one study demonstrated that the 12/12 genotype was significantly less frequent in ADHD cases compared to controls, while a sec…

Genetics and epigenetic pathways of disease [NCMLS 6]MedizinNeuroinformatics [DCN 3]0302 clinical medicinePolymorphism (computer science)GenotypePerception and Action [DCN 1]Childhealth care economics and organizationsSerotonin transporterGenetics (clinical)GeneticsSerotonin Plasma Membrane Transport Proteins0303 health sciencesDepression030305 genetics & heredityTransmission disequilibrium testhumanitiesVariable number tandem repeatPsychiatry and Mental healthChild Preschool/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFunctional Neurogenomics [DCN 2]medicine.medical_specialtyAdolescenteducationBiologybehavioral disciplines and activitiesMental health [NCEBP 9]Genomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciencesCellular and Molecular NeuroscienceSDG 3 - Good Health and Well-beingCognitive neurosciences [UMCN 3.2]Internal medicinemental disordersmedicineAttention deficit hyperactivity disorderHumansGenetic Predisposition to Diseaseddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAssociation (psychology)Gene030304 developmental biologyFamily HealthPolymorphism Geneticbusiness.industryMood Disordersmedicine.diseaseMoodEndocrinologyMood disordersGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with Hyperactivitybiology.proteinbusiness030217 neurology & neurosurgery
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Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.

2014

Previous studies have suggested that polymorphisms in CASP8 on chromosome 2 are associated with breast cancer risk. To clarify the role of CASP8 in breast cancer susceptibility, we carried out dense genotyping of this region in the Breast Cancer Association Consortium (BCAC). Single-nucleotide polymorphisms (SNPs) spanning a 1 Mb region around CASP8 were genotyped in 46 450 breast cancer cases and 42 600 controls of European origin from 41 studies participating in the BCAC as part of a custom genotyping array experiment (iCOGS). Missing genotypes and SNPs were imputed and, after quality exclusions, 501 typed and 1232 imputed SNPs were included in logistic regressionmodels adjusting for stud…

Genotyping TechniquesResearch Support U.S. Gov't P.H.S.CASP8 and FADD-Like Apoptosis Regulating ProteinGenome-wide association studyP.H.S.Medical and Health SciencesBreast and Ovarian Cancer Susceptibility (BOCS) StudyMedizinische FakultätGenetics(clinical)Non-U.S. Gov'tGenetics (clinical)GeneticsGenetics & HeredityvariantsCaspase 8Research Support Non-U.S. Gov'tAssociation Studies ArticlesGeneral MedicineBiological Sciencesddc:Chromosomes Human Pair 2kConFab InvestigatorsFemaleGENICA NetworkAustralian Ovarian Cancer Study GroupEuropean Continental Ancestry GroupNon-P.H.S.Single-nucleotide polymorphismBreast Neoplasms-BiologyResearch SupportPolymorphism Single NucleotideWhite PeopleN.I.H.Breast cancerResearch Support N.I.H. ExtramuralSDG 3 - Good Health and Well-beingmedicineGeneticsJournal ArticleHumansGenetic Predisposition to Diseaseddc:610geneGenotyping TechniquesGenotypingMolecular BiologyGenetic associationdiseaseExtramuralProteinsOdds ratiomedicine.diseasesusceptibility lociMinor allele frequencyCase-Control Studiesgenome-wide associationenhancersU.S. Gov'tcasp8Research Support U.S. Gov't Non-P.H.S.Genome-Wide Association Study
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Fringed Life Satisfaction? A Life-Course Perspective on the Impact of International Migration on Subjective Well-Being

2018

This chapter investigates the role of personal life events in changing levels of life satisfaction and tries to contrast migrants to native population in this respect. Marriage, divorce, separation, widowhood, and having children are considered as potential triggers for differential transformations of migrant lives as compared to non-migrant. The main assumption relies on the increased uncertainty and destandardization of migrant life course, given their spatial mobility that disrupts stages of traditional life cycle. The findings from the panel data obtained from German Socio-Economic Panel (GSOEP; Germany), collected during more than three decades, reveal higher sensitivity of migrants to…

GermanNative populationlanguagePersonal lifeLife course approachLife satisfactionDifferential (mechanical device)Demographic economicsSubjective well-beingPsychologylanguage.human_languagePanel data
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Analysis of the impact of leisure on well-being and distress in ageing

2016

This research aimed to study the effect of leisure activities in the psychological well-being, attitude for leisure and distress of seniors. The sample consisted of 403 participants (male -- 150; female -- 253), with a range age between 53--93 years. Regarding the perception of health condition, 333 subjects were considered independent (81.4%) while 70 participants were considered dependent (17.1%). Research is quantitative, with a design-cross. The instruments used were the MHI and the LAS. Main results showed that subjects that are involved in leisure activities presented high level of well-being and attitude for leisure (p[Hotelling's Trace = 0.077; F (3,341) = 8.733; p = 0.00]. The resu…

Gerontology030505 public healthmedia_common.quotation_subjectHealth conditionMental health03 medical and health sciencesDistress0302 clinical medicineAgeingPerceptionWell-being030212 general & internal medicine0305 other medical sciencePsychologymedia_commonProceedings of the Fourth International Conference on Technological Ecosystems for Enhancing Multiculturality
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Towards a physically more active lifestyle based on one's own values: study design of a randomized controlled trial for physically inactive adults

2013

Background This randomised controlled trial demonstrates the effectiveness of a value-based intervention program to encourage a physically more active lifestyle among physically inactive adults aged 30 to 50 years. The conceptual framework of the program is based on an innovative behavioural therapy called Acceptance and Commitment Therapy (ACT) that aims to increase an individual’s psychological flexibility and support behaviour change towards a higher quality and more meaningful life. Methods Participants will be randomly allocated to a feedback group (FB) or an Acceptance and Commitment based (ACT + FB) group. Both the groups will receive written feedback about their objectively measured…

GerontologyAdultMalemedicine.medical_treatmenthyväksymis- ja omistautumisterapiaEffectivenessPersonal SatisfactionAcceptance and commitment therapyMeaningful lifePsychological well-beinglaw.inventionStudy ProtocolRandomized controlled trialPsykologinen hyvinvointilawSurveys and QuestionnairesmedicineHumansAdultsBehaviourAcceptance and Commitment TherapykäyttäytyminenExerciseaikuisetSedentary lifestyleHOTMotivationCognitive Behavioral Therapybusiness.industryPhysical activitytuloksellisuusPublic Health Environmental and Occupational HealthFlexibility (personality)Middle AgedvaikuttavuusACTPsychological well-beingCognitive therapyFemaleBiostatisticsSedentary BehaviorbusinessAttitude to Healthfyysinen aktiivisuus
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Community garden initiatives addressing health and well‐being outcomes: A systematic review of infodemiology aspects, outcomes, and target populations

2021

Previous research has suggested that activities such as community gardens could offer a wide range of health benefits. The aim of the article is to systematically review the available literature to analyse the magnitude of the phenomenon, the geographical distribution, and the main characteristics in terms of health outcomes and target populations. The search addresses the question whether the activity in community gardens improves health and well-being outcomes of individuals. From the total amount of 7226, 84 selected articles showed that:(1) up to 50% are published by U.S. universities or institutions; (2) up to 44% of the studies considered “community gardens” as the main activity of th…

GerontologyAdultmedicine.medical_specialtyHealth Toxicology and Mutagenesismedia_common.quotation_subjectDistribution (economics)lcsh:Medicine010501 environmental sciences01 natural sciencesOutcome (game theory)Infodemiology03 medical and health sciences0302 clinical medicinePromotion (rank)well-beingPhenomenonmedicineHumans030212 general & internal medicine0105 earth and related environmental sciencesmedia_commonSettore MED/14 - NefrologiaWell‐beingPublic healthbusiness.industryPublic healthlcsh:RPublic Health Environmental and Occupational HealthUrban HealthGardeningCommunity gardens; Health promotion; Public health; Urban greenspace; Well‐being; Adult; Humans; Urban Health; Gardening; GardensSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeHealth promotionCommunity gardens Health promotion Public health Urban greenspace Well‐beingWell-beingHealth promotionUrban greenspaceSystematic ReviewCommunity gardensPsychologybusinessGardens
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Happy Aged People Are All Alike, While Every Unhappy Aged Person Is Unhappy in Its Own Way

2011

Aging of the world’s population represents one of the most remarkable success stories of medicine and of humankind, but it is also a source of various challenges. The aim of the collaborative cross-cultural European study of adult well being (ESAW) is to frame the concept of aging successfully within a causal model that embraces physical health and functional status, cognitive efficacy, material security, social support resources, and life activity. Within the framework of this project, we show here that the degree of heterogeneity among people who view aging in a positive light is significantly lower than the degree of heterogeneity of those who hold a negative perception of aging. We base…

GerontologyAgingDatabases FactualHappinesslcsh:MedicineSocial PolicySocial and Behavioral SciencesEngineeringSociologySurveys and QuestionnairesMedicineData MiningCluster AnalysisCooperative Behaviorlcsh:Sciencemedia_commonCausal modelAged 80 and overeducation.field_of_studyMultidisciplinaryPhysicsMiddle AgedSocial NetworksInterdisciplinary PhysicsMedicinePsychological resilienceSocial psychologyResearch Articlemedia_common.quotation_subjectPopulationStatistical MechanicsSocial supportLife ExpectancyHumanseducationDemographyAgedbusiness.industryPerspective (graphical)lcsh:RReproducibility of ResultsSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)GeriatricsComputational SociologyWell-beingSignal ProcessingHappinessLife expectancylcsh:QbusinessNetwork Theory Statistical Physics GeriatricsPLoS ONE
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