Search results for "Wester"
showing 10 items of 1157 documents
Properties of sea urchin coelomocyte agglutinins
1996
We examined some biological activities of a 200-kDa glycoprotein, referred to as Paracentrotus lividus vitellogenin, contained both in the coelomic fluid and in a subpopulation of coelomocytes called «colourless spherula cells». Cell-free coelomic fluid, coelomocyte lysate and supernatant obtained after coelomocyte washings were assayed for hemagglutinating activity. All samples agglutinated rabbit erythrocytes in a calcium-dependent way. The comparison between the electrophoretic patterns of erythrocyte lysates, before and after incubation with the coelomic fluid, revealed that a 200-kDa band was obtained from membranes of agglutinated erythrocytes. In addition, polyclonal antibodies again…
The Roots of Chaadaev’s Philosophical Thought
2016
Pierwsza eurocentryczna koncepcja filozofii historii została stworzona przez Piotra Czaadajewa. Według tego chrześcijańskiego myśliciela jej ideał najlepiej odzwierciedlała średniowieczna Europa. Czaadajew czytał Kanta, Hegla i Schellinga, ale to francuscy filozofowie katoliccy: de Maistre, de Bonald, Ballanche, Chateaubriand i Lamennais, wywarli na niego największy wpływ. Specyficzny rodzaj konserwatywnego okcydentalizmu Czaadajewa charakteryzowało oskarżenie społeczeństwa rosyjskiego o brak tradycji, które mogłyby identyfikować Rosję z historią Europy. Według Czaadajewa kulturę rosyjską charakteryzuje brak ciągłości; nowe pomysły pojawiają się niespodziewanie, są pozbawione podstaw i brak…
S-type lectins occur also in invertebrates: high conservation of the carbohydrate recognition domain in the lectin genes from the marine sponge Geodi…
1993
The marine sponge Geodia cydonium contains several lectins. The main component, called lectin-1, is composed of three to four identical subunits. The subunits of the lectins were cloned from a cDNA library; two clones were obtained. From the deduced aa sequence of one clone, LECT-1, a mol. wt of 15,313 Da is calculated; this value is in good agreement with mass spectrometric analysis of 15,453 +/- 25 Da. The sequence of another clone, LECT-2, was analysed and the aa sequence was deduced (15,433 Da). The two subunits have a framework sequence of 38 conserved aa which are characteristic for the carbohydrate-binding site of vertebrate S-type lectins. Clustering of lectin sequences of various s…
CAMPANIAN WINE FOR PUNIC SICILY: PETROGRAPHIC AND ARCHAEOLOGICAL STUDIES OF GRAECO-ITALIC AMPHORAE FROM PALERMO
2018
This contribution proposes a combination of archaeological fabric analysis and petrographic research applied to the study of 35 sherds of Graeco-Italic amphorae mostly found in Palermo, but also in Pantelleria and Malta (Tab. 1). The provenance identification derived from both approaches gives evidence for the arrival, in North-Western Sicily, of presumable wine amphorae from central-Tyrrhenian Italy since the very late 4th century BC. The production of the majority of the material has been confidentially attributed to the area of the Gulf of Naples/Ischia, but a second large group originates from several, still unidentified production sites to be located along the coastal strip of Campania…
WRN protects against topo I but not topo II inhibitors by preventing DNA break formation
2008
The Werner syndrome helicase/3′-exonuclease (WRN) is a major component of the DNA repair and replication machinery. To analyze whether WRN is involved in the repair of topoisomerase-induced DNA damage we utilized U2-OS cells, in which WRN is stably down-regulated (wrn-kd), and the corresponding wild-type cells (wrn-wt). We show that cells not expressing WRN are hypersensitive to the toxic effect of the topoisomerase I inhibitor topotecan, but not to the topoisomerase II inhibitor etoposide. This was shown by mass survival assays, colony formation and induction of apoptosis. Upon topotecan treatment WRN deficient cells showed enhanced DNA replication inhibition and S-phase arrest, whereas af…
Evidence of oxidative stress in very long chain fatty acid--treated oligodendrocytes and potentialization of ROS production using RNA interference-di…
2011
X-linked adrenoleukodystrophy (X-ALD) and pseudo neonatal adrenoleukodystrophy (P-NALD) are neurodegenerative demyelinating diseases resulting from the functional loss of the peroxisomal ATP-binding cassette transporter D (ABCD1) and from single peroxisomal enzyme deficiency (Acyl-CoA oxidase1: ACOX1), respectively. As these proteins are involved in the catabolism of very long chain fatty acids (VLCFA: C24:0, C26:0), X-ALD and P-NALD patients are characterized by the accumulation of VLCFA in plasma and tissues. Since peroxisomes are involved in the metabolism of reactive oxygen species (ROS) and nitrogen species (RNS), we examined the impact of VLCFA on the oxidative status of 158N murine o…
Riflessioni conclusive
2015
The rural sanctuary in the San Cataldo district, between the territories of Terrasini and Partinico, is mentioned by the written sources since the XII century, but the surviving architectural structures date back to the 16th century. The site, abandoned since the 1950s and now restored by the Soprintendenza ai Beni Culturali of Palermo who carried out archaeological excavations in this area in 2000 and 2014, over the centuries has been an important aggregation pole in order to the cultural and religious identity of the rural communities in northwestern Sicily, in relation to the fertile hinterland through the Roma viability (via consolare Valeria) .
WATER MASSES EXCHANGE THROUGH THE STRAIT OF SICILY DURING THE LAST DEGLACIAL PERIOD AND THE HOLOCENE
2022
The main goal of this thesis is to explore the inter-basin connection between the eastern and the western Mediterranean (E- and W-Med, respectively) during the last deglacial and Holocene periods (last 15 kyr). The thesis is based on the study of a sediment core recovered at the west flank of Sicily channel (W-Sicily), strategically located under the current path of the surface Atlantic waters and directly below the present-day hydrographic boundary layer between the Eastern Mediterranean Sourced Water (EMSW) and the Western Mediterranean Deep Water (WMDW). This key location allow to explore past changes in both surface and deep water exchange between the E and the W-Med. In this thesis, a …
Leishmania tarentolae and Leishmania infantum in humans, dogs and cats in the Pelagie archipelago, southern Italy.
2021
Visceral leishmaniasis (VL) caused by Leishmania infantum is endemic in the Mediterranean basin with most of the infected human patients remaining asymptomatic. Recently, the saurian-associated Leishmania tarentolae was detected in human blood donors and in sheltered dogs. The circulation of L. infantum and L. tarentolae was investigated in humans, dogs and cats living in the Pelagie islands (Sicily, Italy) by multiple serological and molecular testing. Human serum samples (n = 346) were tested to assess the exposure to L. infantum by immunofluorescence antibody test (IFAT), enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) and to L. tarentolae by IFAT. Meanwhile, sera from do…
Impact of the high share of converter-interfaced generation on electromechanical oscillations in Continental Europe power system
2020
This study investigates the effects of converter-interfaced generation integration on the dynamic response of the power system of Continental Europe. The system is analysed with a large-scale dynamic model of the entire synchronous area, considering different instantaneous integration percentages of converter-interfaced generation across the system. The study focuses on the reduction of the overall available kinetic energy and the impact on frequency dynamics and system oscillations. The dynamic model of the system originally provided by ENTSO-E is further developed according to a specific methodology, replacing a determined amount of synchronous generation and introducing a corresponding a…