Search results for "White People"

showing 6 items of 206 documents

Heritability of corneal refraction and corneal astigmatism: a population-based twin study among 66- to 79-year-old female twins.

2012

. Purpose:  To examine the heritability of corneal refraction power (CR) and corneal astigmatism (AST) in older women. Methods:  Corneal refraction and AST were measured by IOL master in 52 monozygotic (MZ) and 47 dizygotic (DZ) female twin pairs aged 66–79 years. The relative contribution of genetic and environmental factors to individual differences in CR was estimated by applying an independent pathway model to the twin data and AST by intraclass correlations (ICC). Results:  For the right eye, mean CR was 44.58 dioptres (D) (standard deviation (SD) ±1.28) When comparing CR of the right and left eye between MZ and DZ, no significant difference was found. Mean AST was 0.77 D (SD ±0.44) wi…

medicine.medical_specialtyInheritance PatternsPopulation basedAstigmatismRefraction OcularWhite People03 medical and health sciences0302 clinical medicineCorneaOphthalmologyDiseases in TwinsTwins DizygoticMedicineHumansFinland030304 developmental biologyAgedGenetics0303 health sciencesModels Geneticbusiness.industrySignificant differenceAstigmatismGeneral MedicineTwins MonozygoticHeritabilitymedicine.diseaseTwin studyConfidence intervalOphthalmologymedicine.anatomical_structure030221 ophthalmology & optometryFemaleGene-Environment InteractionbusinessCorneal astigmatismActa ophthalmologica
researchProduct

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

2013

The author manuscript of this article is open access and is freely available online at PubMed Central

medicine.medical_specialtyKeratoconusCorneal Pachymetrygenetic structuresthickness; keratoconus; geneGlaucomaOcular hypertensionGenome-wide association studyBiologyReal-Time Polymerase Chain ReactionKeratoconusWhite PeopleArticleCentral corneal thicknessCorneaAsian PeopleOphthalmologyCorneaOdds RatioGeneticsmedicineHumansCorneal pachymetrymedicine.diagnostic_testForkhead Box Protein O1Forkhead Transcription FactorsGlaucomaOdds ratioMicroarray Analysismedicine.diseaseConfidence intervaleye diseasesFibronectinsmedicine.anatomical_structureGenetic Locisense organsGenome-Wide Association Study
researchProduct

Acute reversible parkinsonism in a diabetic-uremic patient.

2005

Acute movement disorders with basal ganglia lesions have been recently described in diabetic-uremic patients of Asian descent. The process is often reversible, with a favourable clinical outcome. Metabolic (i.e. uremic toxins) and microangiopathic changes have been suggested to be involved in its pathophysiology, even though racial and/or genetic factors might play a role too. In this report, we present a Caucasian diabetic patient with a long-lasting mild uremia in which acute parkinsonism occurred after a steep and unexpected increase of the serum creatinine. The follow-up demonstrated a significant improvement of the neurological signs and symptoms, the creatinine level lowered close to …

medicine.medical_specialtyMovement disordersacute parkinsonismGastroenterologyWhite PeopleDiabetes Complicationschemistry.chemical_compoundParkinsonian DisordersDiabetes mellitusInternal medicinemedicineHumansAgedUremiaCreatininediabetes mellitubusiness.industryParkinsonismGeneral Medicinemedicine.diseasePathophysiologyUremiaSurgerychemistryCreatininebasal gangliaAcute DiseaseSurgeryFemaleNeurology (clinical)medicine.symptomDifferential diagnosisbusinessKidney diseaseClinical neurology and neurosurgery
researchProduct

Absence of the lactase-persistence-associated allele in early Neolithic Europeans.

2007

Lactase persistence (LP), the dominant Mendelian trait conferring the ability to digest the milk sugar lactose in adults, has risen to high frequency in central and northern Europeans in the last 20,000 years. This trait is likely to have conferred a selective advantage in individuals who consume appreciable amounts of unfermented milk. Some have argued for the “culture-historical hypothesis,” whereby LP alleles were rare until the advent of dairying early in the Neolithic but then rose rapidly in frequency under natural selection. Others favor the “reverse cause hypothesis,” whereby dairying was adopted in populations with preadaptive high LP allele frequencies. Analysis based on the cons…

medicine.medical_treatmentPopulationLactoseBiologyDNA MitochondrialPolymorphism Single NucleotideBone and BonesWhite PeopleNOLactose IntolerancemedicineHumansAlleleeducationSelectionAllele frequencyAllelesHistory AncientLactaseGeneticseducation.field_of_studyMultidisciplinaryNatural selectionAncient DNAHaplotypeLactaseEmigration and ImmigrationBiological SciencesAncient DNA Dairying SelectionEuropeDairyingLactase persistenceAncient DNAGenetics PopulationTandem Repeat SequencesToothProceedings of the National Academy of Sciences of the United States of America
researchProduct

“At the Western Palace”: The Dehumanization of Whiteness, Americanness, and Chinese-Americanness in Maxine Hong Kingston’s The Woman Warrior

2021

The dehumanization of whiteness in Maxine Hong Kingston’s The Woman Warrior (1976) inheres in the overarching ghosthood metaphor. While first generation Chinese American immigrants in The Woman Warrior attribute the power of transforming people into ghosts to the United States of America as a country, the questioning of a person’s humanity by calling them a “ghost” is not reserved for white people alone. Chinese American immigrants also run the risk of losing their humanity and becoming ghosts if they renounce their relatives and their heritage. The husband of the first-person narrator’s Chinese aunt, Moon Orchid, is an example of a Chinese American man, who turns into a ghost on account of…

savagesghostsmedia_common.quotation_subjectMaxine Hong KingstonArt historyArtThe Woman WarriorChinese immigrantsbarbarianspoint of viewDehumanizationnarrationwhite AmericanswhitenessChinese Americanswhite peoplemedia_commonPolish Journal for American Studies
researchProduct

Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry

2009

We conducted meta-analyses of genome-wide association studies (GWAS) for atrial fibrillation (AF) in participants from five community-based cohorts. Meta-analyses of 896 prevalent (15,768 referents) and 2,517 incident (21,337 referents) AF cases identified a novel locus for AF (ZFHX3, rs2106261, risk ratio [RR]=1.19; P=2.3×10−7), an association that was replicated in the German AF Network (odds ratio=1.44; P=1.6×10−11). Combining the discovery and replication results, rs2106261 was significantly associated with AF (RR=1.25; P=1.8×10−15).

single nucleotideEuropean Continental Ancestry Group/*geneticsmedicine.medical_specialtyMutation/*geneticsGenome-wide association study030204 cardiovascular system & hematologyBiologyPolymorphism Single NucleotideArticleWhite PeoplepolymorphismHomeodomain Proteins/*genetics03 medical and health sciences0302 clinical medicineMeta-Analysis as TopicInternal medicineAtrial FibrillationGeneticsmedicineHumansGenetic Predisposition to Disease030304 developmental biologyGenetic associationHomeodomain Proteinsddc:6160303 health sciencesAtrial Fibrillation/*geneticsReproducibility of ResultsAtrial fibrillationOdds ratioPolymorphism Single Nucleotide/geneticsmedicine.disease*Genetic Predisposition to DiseaseMeta-analysisRelative riskMutationCohortepidemiologyChromosomes Human Pair 16/geneticsChromosomes Human Pair 16Genome-Wide Association StudyNature Genetics
researchProduct