Search results for "Witch"
showing 10 items of 542 documents
Opioid Plasma Concentrations during a Switch from Transdermal Fentanyl to Methadone
2007
Opioid switching is often used to improve the opioid response in patients with cancer experiencing poor analgesia or adverse effects. When switching between drugs with delayed effect because of pharmacokinetics or type of delivery, concerns exist about the correct timing of introducing the second drug after stopping the previous one. The aim of this study was to assess plasmatic changes of fentanyl and methadone underlying the clinical events occurring during opioid switching. Eighteen patients with cancer receiving transdermal fentanyl with uncontrolled pain and/or moderate to severe opioid adverse effects, were switched to oral methadone using an initial fixed ratio of 1:20. Fentanyl patc…
Efficacy of single-source rapid kV-switching dual-energy CT for characterization of non-uric acid renal stones: a prospective ex vivo study using ant…
2019
Purpose To investigate the accuracy of rapid kV-switching single-source dual-energy computed tomography (rsDECT) for prediction of classes of non-uric-acid stones. Materials and methods Non-uric-acid renal stones retrieved via percutaneous nephrolithotomy were prospectively collected between January 2017 and February 2018 in a single institution. Only stones >= 5 mm and with pure composition (i.e., >= 80% composed of one component) were included. Stone composition was determined using Fourier Transform Infrared Spectroscopy. The stones were scanned in 32-cm-wide anthropomorphic whole-body phantom using rsDECT. The effective atomic number (Zeff), the attenuation at 40 keV (HU40), 70 ke…
Acceptability of Intimate Partner Violence among Male Offenders: The Role of Set-Shifting and Emotion Decoding Dysfunctions as Cognitive Risk Factors.
2019
Attitudes towards the acceptability of intimate partner violence against women (IPVAW) contribute to an increased risk of IPVAW perpetration, and these attitudes are common among IPVAW offenders. Research suggests that IPVAW offenders present cognitive deficits related to information processing. Little is known, however, about how these deficits are related to the acceptability of IPVAW. The main aim of this study was to explore the relationship between specific cognitive deficits (i.e., deficits in attention switching, set-shifting, and emotion decoding abilities) and the acceptability of IPVAW in a sample of 84 IPVAW offenders. Results revealed that IPVAW offenders with deficits in attent…
Is the V˙o 2 slow component dependent on progressive recruitment of fast-twitch fibers in trained runners?
2001
The goal of this study was to use spectral analysis of EMG data to test the hypothesis that the O2 uptake (V˙o 2) slow component is due to a recruitment of fast fibers. Thirteen runners carried out a treadmill test with a constant speed, corresponding to 95% of the velocity associated with maximal V˙o 2. TheV˙o 2 response was fit with the classical model including three exponential functions. Electrical activity of six lower limb muscles (vastus lateralis, soleus, and gastrocnemius of both sides) was measured using electromyogram surface electrodes. Mean power frequency (MPF) was used to study the kinetics of the electromyogram discharge frequency. Three main results were observed: 1) a co…
Relation between muscle mass, motor units and type of training in master athletes.
2014
OBJECTIVE: The aim of this study was to measure the number of motor units and muscle mass in power-trained and endurance-trained master athletes compared with community-dwelling older adults. METHODS: Seventy-five master athletes (52 power- and 23 endurance-trained athletes) were recruited at the 2012 European Veteran Athletics Championships in Zittau (Germany). One hundred and forty-nine community-dwelling older adults served as controls. In all participants, the motor unit number index (MUNIX) in the hypothenar muscle and whole body muscle mass was determined by bioelectrical impedance analysis (BIA). RESULTS: In both male and female master athletes, there were significant negative correl…
Neuromuscular fatigue induced by an isotonic heavy-resistance loading protocol in knee extensors.
2009
Abstract The main aim of this study was to assess neuromuscular fatigue during a typical high-load, low-repetition loading protocol. Muscle stimulations were used to assess maximum voluntary contraction, resting single- and double-pulse twitch characteristics, and superimposed double-pulse twitch force (used to calculate voluntary activation) before and after an acute knee extension loading protocol. In our participants, who had previous resistance training experience, the mean voluntary activation level was 96.2% in an unfatigued state. Maximum voluntary contraction (−11.8%), resting double-pulse twitch force (−10.6%), and voluntary activation (−2.1%) were markedly decreased as a consequen…
Neuromuscular Differences Between Endurance-Trained, Power-Trained, and Sedentary Subjects
2003
This study tested the hypothesis that neuromuscular characteristics of plantar flexor (PF) and knee extensor (KE) muscles explain differences of both performance in vertical jump and maximal voluntary isometric contraction (MVC) between endurance-trained (END, n = 9), power-trained (POW, n = 8), and sedentary subjects (SED, n = 8). Evoked twitch characteristics of PF and KE were measured. MVC, maximal voluntary activation (%VA) of KE, and performance in vertical jump were also measured. POW have higher maximal rate of twitch force development (MRFD) than SED and END for both PF (p < 0.05) and KE (p < 0.01); %VA and MVC were higher for POW and END than SED (p < 0.01). Higher performances wer…
Neuromuscular fatigue following constant versus variable-intensity endurance cycling in triathletes
2008
International audience; The aim of this study was to determine whether variable power cycling produced greater neuromuscular fatigue of knee extensor muscles than constant power cycling at the same mean power output. Eight male triathletes (age : 33 ± 5 yr, mass : 74 ± 4 kg, OV&2max : 62 ± 5 ml.kg-1.min-1, maximal aerobic power : 392 ± 17 W) performed two 30 min trials on a cycle ergometer in a random order. Cycling exercise was performed either at a constant power output (CP) corresponding to 75% of the maximal aerobic power (MAP) or a variable power output (VP) with alternating ± 15%, ± 5%, and ± 10% of 75% MAP approximately every 5 min. Maximal voluntary contraction (MVC) torque, maximal…
Neural activation after maximal isometric contractions at different muscle lengths.
2006
DESBROSSES K., N. BABAULT, G. SCAGLIONI, J.-P. MEYER, and M. POUSSON. Neural Activation after Maximal Isometric Contractions at Different Muscle Lengths. Med. Sci. Sports Exerc., Vol. 38, No. 5, pp. 937–944, 2006. Purpose: To investigate i) whether neural activation dependence on muscle length is preserved with neuromuscular fatigue and ii) whether fatigue induced by a maximal isometric exercise is muscle length dependent. Methods: Twelve male subjects performed two fatiguing quadriceps muscle exercises: FS is the fatigue carried out at short muscle length (S) (S = 40- of knee flexion) and FL is the fatigue at long muscle length (L) (L = 100-). Before and after each fatiguing exercise (i.e.…
Type 1 Muscle Fiber Hypertrophy after Blood Flow–restricted Training in Powerlifters
2018
PURPOSE: To investigate the effects of blood flow restricted resistance exercise (BFRRE) on myofiber areas (MFA), number of myonuclei and satellite cells (SC), muscle size and strength in powerlifters. METHODS Seventeen national level powerlifters (25+/-6 yrs [mean+/-SD], 15 men) were randomly assigned to either a BFRRE group (n=9) performing two blocks (week 1 and 3) of five BFRRE front squat sessions within a 6.5-week training period, or a conventional training group (Con; n=8) performing front squats at ~70% of one-repetition maximum (1RM). The BFRRE consisted of four sets (first and last set to voluntary failure) at ~30% of 1RM. Muscle biopsies were obtained from m. vastus lateralis (VL…