Search results for "Wort"

Metabolic syndrome, insulin resistance and sleepiness in real-life obstructive sleep apnoea.

2011

The metabolic syndrome shows a variable prevalence in obstructive sleep apnoea (OSA), and its association with insulin resistance or excessive daytime sleepiness in OSA is unclear. This study assessed the following in consecutive patients with newly diagnosed OSA: 1) the prevalence of metabolic syndrome; and 2) its association with insulin resistance and daytime sleepiness. Metabolic syndrome (National Cholesterol Education Program Adult Treatment Panel (NCEP- ATP) III criteria), insulin resistance (Homeostatic Model Assessment (HOMA) index, n5288) and daytime sleepiness (Epworth Sleepiness Scale) were assessed in 529 OSA patients. The prevalence of metabolic syndrome was 51.2%, which incre…

Investigation and management of residual sleepiness in CPAP-treated patients with obstructive sleep apnoea: the European view

2022

International audience; Excessive daytime sleepiness (EDS) is a major symptom of obstructive sleep apnoea (OSA), defined as the inability to stay awake during the day. Its clinical descriptors remain elusive, and the pathogenesis is complex, with disorders such as insufficient sleep and depression commonly associated. Subjective EDS can be evaluated using the Epworth Sleepiness Scale, in which the patient reports the probability of dozing in certain situations; however, its reliability has been challenged. Objective tests such as the multiple sleep latency test or the maintenance of wakefulness test are not commonly used in patients with OSA, since they require nocturnal polysomnography, da…

Reliability of automatic detection of AHI during positive airway pressure treatment in obstructive sleep apnea patients: A “real-life study”

2021

Introduction: Automatic event detection (AED) of residual apnea-hypopnea index (AHI) by ventilators is a current practice in sleep and mechanical ventilation Units but this methodology has not been validated in an unselected population of OSA patients. Aim of the present study was to assess in a “real-life” condition the reliability of AED during PAP therapy by the in-built software compared to full polysomnography during follow-up. Methods: We enrolled 300 OSA patients (105 F; AHI 45.3 ± 27.8) already on Positive airway pressure (PAP) therapy: 53% of the patients were on CPAP while other modalities were used in the rest of the sample. Results: Overall, the built-in software identified resi…

On the mend of bryophyte conservation in Spain: preparing a proposal for the inclusion of bryophytes in national species protection catalogues

2018

The Spanish bryoflora contains 1291 taxa, 272 of them included in the Spanish Red List under any threat category. Although bryophytes show a low rate of endemicity compared to vascular flora, Spanish administration’s responsibility for the conservation of these plants is very high, since the country has 63 exclusive or rare species on a European or world scale. However, the representation of this group of plants in the Spanish legislation on species conservation is merely anecdotal. Royal Decree 139/2011 of 4 February develops a list of wild protected species (LESRPE and CEEA, Spanish abbreviations) and includes only 10 species of bryophytes, all of them from the Directive Habitats and the …

The Dark Side of Value Co-Creation: The Example of French Commercial Architecture

2018

Innovation is a network activity where different actors collaborate. An ethnographic survey of the French commercial architecture industry highlights the ambivalence of this co-production process. The results identify the sources of co-creation and co-destruction related both to the motivations of the actors and their interactions and examines their consequences. Retailers are encouraged to reposition themselves as project leaders, responsible for both assigning roles and mediating between the creative and technical functions. The development of new communication platforms to overcome interpretive biases between the diverse set of actors is also recommended.

New national and regional bryophyte records, 65

2021

Pseudoamblystegium subtile (Hedw.) Vanderp. & Hedenäs. CONTRIBUTORS: R. Gabriel, M. Kubová, C. Sérgio and I. Soares Albergaria. PORTUGAL, AZORES: Terceira Island, Angra do Heroísmo, municipal garden ‘Jardim Duque da Terceira’, 38° 39′ 24.0′′N, 27°13′ 05.99′′W, 31 m a.s.l, on the base of a shrub, in acidic conditions, 7 April 2017, leg. Michaela Kubová s.n. (AZU). A new understanding of the pleurocarpous moss species Pseudoamblystegium subtile was proposed by Vanderpoorten and Hedenäs (2009). The new genus is separated from the other Amblystegiaceae primarily due to its phylogenetic consistency and is characterised by the possession of leaves with a very short nerve, and erect capsules (Vand…

L’universo atlantico di Sacred Hunger

2007

Inhibition of FcεRI-mediated Activation of Rat Basophilic Leukemia Cells by Clostridium difficile Toxin B (Monoglucosyltransferase)

1996

Abstract Treatment of rat basophilic leukemia (RBL) 2H3-hm1 cells with Clostridium difficile toxin B (2 ng/ml), which reportedly depolymerizes the actin cytoskeleton, blocked [3H]serotonin release induced by 2,4-dinitrophenyl-bovine serum albumin, carbachol, mastoparan, and reduced ionophore A23187-stimulated degranulation by about 55-60%. In lysates of RBL cells, toxin B 14C-glucosylated two major and one minor protein. By using two-dimensional gel electrophoresis and immunoblotting, RhoA and Cdc42 were identified as protein substrates of toxin B. In contrast to toxin B, Clostridium botulinum transferase C3 that selectively inactivates RhoA by ADP-ribosylation did not inhibit degranulation…

Standardisation of Artificial Intelligence: Making a “New World” Brave, with Support of Human Requirements in a Machine Intelligence Environment

2022

In line with previous industrial revolutions, standardisation must accompany the deployment of artificial intelligence systems that promise to revolutionise the way we live (home automation, autonomous vehicles, EdTech, etc.) and work (collaborative industrial robots, agricultural robots, inspection and maintenance robots, LegalTech, FinTech, etc.). The standards produced and promoted in Europe will be resolutely geared towards the protection of people and property, thus promoting the acceptability of these intelligent systems and the common interest. They will have to cover the requirements expected of AIs, but also the means and methods for assessing them. The new standards will have to c…

Vulnerability evaluation of distributed reputation management systems

2017

In distributed environments, Reputation Management Systems (RMSs) aim to estimate agents' trustworthiness by exploiting different sources of information. The distributed nature of these systems makes them vulnerable to several types of security attacks, and the response provided by a specific RMS depends on various factors, such as the algorithms adopted for estimating the reputation values and the communication protocols used to enable the cooperation among agents. This work examines the most important security attacks against RMSs and proposes a set of metrics for a quantitative evaluation of the RMS vulnerabilities. A parallel simulation framework is used to automatically give a vulnerab…