Search results for "X-ray Diffraction"

showing 10 items of 280 documents

Synthesis, Characterization, Thermal and Antimicrobial studies of N-substituted Sulfanilamide derivatives

2014

Abstract Four sulfanilamide derivatives N -[4-(phenylsulfamoyl)phenyl]acetamide (1), 4-amino- N -phenylbenzenesulfonamide (2), N -[4-(phenylsulfamoyl)phenyl]benzamide (3) and N -{4-[(3-chlorophenyl)sulfamoyl]phenylbenzamide (4) were synthesized and characterized by Infra-Red (IR), Nuclear Magnetic Resonance (NMR) and UV–visible (UV–Vis) spectra. Also Liquid Chromatographic (LCMS) and High Resolution Mass Spectrometric (HRMS) methods were used. Crystal structures of 1–4 were determined by single crystal X-ray diffraction (XRD) and their conformational and hydrogen bond (HB) network properties were examined with survey of the literature data. Compounds 1 and 2 crystallize in the same orthorho…

CARBONIC-ANHYDRASE INHIBITORSStereochemistryCrystal structureAntimicrobial activitySOLUBILITYTriclinic crystal systemAnalytical ChemistryInorganic ChemistrySynthesischemistry.chemical_compoundDESIGNSulfanilamidesmedicineSUBLIMATIONCRYSTAL-STRUCTUREThermal analysista116SpectroscopySULFONAMIDE DERIVATIVESHydrogen bondCrystal structureOrganic ChemistryThermal decompositionSulfanilamideX-ray diffractionCrystallographySOLVATIONchemistryACIDOrthorhombic crystal systemAcetamidemedicine.drugMonoclinic crystal systemJournal of Molecular Structure
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Quantitative Raman spectroscopy as a tool to study the kinetics and formation mechanism of carbonates

2013

We have carried out a systematic study of abiotic precipitation at different temperatures of several Mg and Ca carbonates (calcite, nesquehonite, hydrocalcite) present in carbonaceous chondrites. This study highlights the capability of Raman spectroscopy as a primary tool for performing full mineralogical analysis. The precipitation reaction and the structure of the resulting carbonates were monitored and identified with Raman spectroscopy. Raman spectroscopy enabled us to confirm that the precipitation reaction is very fast (minutes) when Ca(II) is present in the solution, whereas for Mg(II) such reactions developed at rather slow rates (weeks). We also observed that both the composition a…

CalciteReaction mechanismChemistryPrecipitation (chemistry)KineticsAnalytical chemistrySpectrum Analysis RamanAtomic and Molecular Physics and OpticsCalcium CarbonateAnalytical ChemistryKineticssymbols.namesakechemistry.chemical_compoundX-Ray DiffractionChondriteX-ray crystallographysymbolsChemical PrecipitationMagnesiumRaman spectroscopyInstrumentationSpectroscopySpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
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Rebalancing β-Amyloid-Induced Decrease of ATP Level by Amorphous Nano/Micro Polyphosphate: Suppression of the Neurotoxic Effect of Amyloid β-Protein …

2017

Morbus Alzheimer neuropathology is characterized by an impaired energy homeostasis of brain tissue. We present an approach towards a potential therapy of Alzheimer disease based on the high-energy polymer inorganic polyphosphate (polyP), which physiologically occurs both in the extracellular and in the intracellular space. Rat pheochromocytoma (PC) 12 cells, as well as rat primary cortical neurons were exposed to the Alzheimer peptide Aβ25-35. They were incubated in vitro with polyphosphate (polyP); ortho-phosphate was used as a control. The polymer remained as Na+ salt; or complexed in a stoichiometric ratio to Ca2+ (Na-polyP[Ca2+]); or was processed as amorphous Ca-polyP microparticles (C…

Calcium Phosphates0301 basic medicineIntracellular SpacePeptidelcsh:Chemistrychemistry.chemical_compoundAdenosine TriphosphateX-Ray DiffractionPolyphosphatesSpectroscopy Fourier Transform Infraredprimary rat cortex neuronslcsh:QH301-705.5SpectroscopyCerebral CortexNeuronschemistry.chemical_classificationmicroparticlesChemistryβ-amyloidGeneral Medicinepathological conditions signs and symptomsComputer Science Applicationsneurotoxic effectsurgical procedures operativeBiochemistryAlzheimer's diseaseIntracellularCell Survivalβ-amyloid; calcium polyphosphate; microparticles; neurotoxic effect; adenosine triphosphate level; PC12 cells; primary rat cortex neuronsArticleCatalysisInorganic Chemistry03 medical and health sciencesmedicineExtracellularotorhinolaryngologic diseasesAnimalsPhysical and Theoretical ChemistryMolecular BiologyneoplasmsAmyloid beta-PeptidesPolyphosphateOrganic ChemistryNeurotoxicityPC12 cellsmedicine.diseaseIn vitrodigestive system diseasesRats030104 developmental biologylcsh:Biology (General)lcsh:QD1-999BiophysicsNanoparticlesAdenosine triphosphatecalcium polyphosphateadenosine triphosphate levelInternational Journal of Molecular Sciences
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Phosphorus recovery by struvite crystallization in WWTPs: Influence of the sludge treatment line operation

2010

Phosphorus recovery by struvite (MgNH(4)PO(4).6H(2)O) crystallization is one of the most widely recommended technologies for treating sludge digester liquors especially in wastewater treatments plants (WWTP) with enhanced biological phosphorus removal (EBPR). In this paper, phosphorus recovery by struvite crystallization is assessed using the rejected liquors resulting from four different operational strategies of the sludge treatment line. Phosphorus precipitation and recovery efficiencies of between 80-90% and 70-85%, respectively, were achieved in the four experiments. The precipitates formed were mainly struvite, followed by amorphous calcium phosphate and, in some experiments, by calci…

Calcium PhosphatesEnvironmental EngineeringStruviteMagnesium Compoundschemistry.chemical_elementElutriationWaste Disposal FluidCalcium CarbonatePhosphatesWater Purificationchemistry.chemical_compoundX-Ray DiffractionChemical PrecipitationWaste Management and DisposalWater Science and TechnologyCivil and Structural EngineeringSewageWaste managementChemistryEcological ModelingPhosphorusReproducibility of ResultsPhosphorusPollutionEnhanced biological phosphorus removalWastewaterStruviteSewage sludge treatmentSewage treatmentAigües residuals Plantes de tractamentCrystallizationAlgorithmsWaste disposal
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X-Ray Diffraction and Multifrequency EPR Study of Radiation-Induced Room Temperature Stable Radicals in Octacalcium Phosphate.

2020

Octacalcium phosphate (OCP) {Ca8H2(PO4)6×5H2O] has attracted increasing attention over the last decade as a transient intermediate to the biogenic apatite for bone engineering and in studies involving the processes of pathological calcification. In this work, OCP powders obtained by hydrolysis of dicalcium phosphate dehydrate were subjected to X- and γ-ray irradiation and studied by means of stationary and pulsed electron paramagnetic resonance at 9, 36 and 94 GHz microwave frequencies. Several types of paramagnetic centers were observed in the investigated samples. Their spectroscopic parameters (components of the g and hyperfine tensors) were determined. Based on the extracted parameters,…

Calcium PhosphatesMaterials scienceFree RadicalsBiophysicsAnalytical chemistryCrystal structureApatite030218 nuclear medicine & medical imaginglaw.invention03 medical and health scienceschemistry.chemical_compound0302 clinical medicineX-Ray DiffractionlawPhase (matter)ApatitesHumansRadiology Nuclear Medicine and imagingIrradiationVascular DiseasesElectron paramagnetic resonanceOctacalcium phosphateMicrowavesRadiationBone DevelopmentPulsed EPRX-RaysElectron Spin Resonance SpectroscopyTemperatureCalcinosischemistryGamma Rays030220 oncology & carcinogenesisvisual_artX-ray crystallographyBone Substitutesvisual_art.visual_art_mediumJoint DiseasesRadiation research
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Influence of β-tricalcium phosphate granule size and morphology on tissue reaction in vivo.

2010

In this study the tissue reaction to five different β-tricalcium phosphate (β-TCP)-based bone substitute materials differing only in size, shape and porosity was analyzed over 60 days, at 3, 10, 15, 30 and 60 days after implantation. Using the subcutaneous implantation model in Wistar rats both the inflammatory response within the implantation bed and the resulting vascularization of the biomaterials were qualitatively and quantitatively assessed by means of standard and special histological staining methods. The data from this study showed that all investigated β-TCP bone substitutes induced the formation of multinucleated giant cells. Changes in size, shape and porosity influenced the int…

Calcium PhosphatesVascular Endothelial Growth Factor AChemokineMaterials scienceCellBiomedical EngineeringNeovascularization PhysiologicBiocompatible MaterialsBiochemistryGiant CellsBiomaterialschemistry.chemical_compoundImplants ExperimentalX-Ray DiffractionIn vivomedicineAnimalsParticle SizeRats WistarMolecular BiologybiologyGranule (cell biology)Acid phosphataseBiomaterialGeneral MedicineAnatomyImmunohistochemistryRatsVascular endothelial growth factormedicine.anatomical_structurechemistryGiant cellOrgan SpecificityBone Substitutesbiology.proteinBiophysicsMicroscopy Electron ScanningBiotechnologyActa biomaterialia
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Fabrication of polyelectrolyte multilayered vesicles as inhalable dry powder for lung administration of rifampicin

2014

A polyelectrolyte complex based on chitosan and carrageenan was used to coat rifampicin-loaded vesicles and obtain a dry powder for inhalation by spray-drying. The polymer complexation on vesicle surface stabilized them and improved their adhesion on airways and epithelia cells. Uncoated liposomes were small in size, negatively charged and able to incorporate large amounts of rifampicin (70%). Coated vesicles were still able to load adequate amounts of drug (∼70%) but the coating process produced larger particles (1 μm) that were positively charged and with a spherical shape. Aerosol performances, evaluated using the next-generation impactor, showed that coated vesicles reached the 50% of f…

Cell SurvivalDrug CompoundingPharmaceutical ScienceCoated vesicleCarrageenanChitosanchemistry.chemical_compoundX-Ray DiffractionCell Line TumorAdministration InhalationHumansParticle SizeAntibiotics Antitubercularchemistry.chemical_classificationChitosanLiposomeChromatographyCalorimetry Differential ScanningVesiclePolymerAdhesionPolyelectrolyteCarrageenanchemistryChemical engineeringLiposomesRifampinInternational Journal of Pharmaceutics
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Total oxidation of naphthalene with high selectivity using a ceria catalyst prepared by a combustion method employing ethylene glycol.

2009

Abstract During the catalytic combustion of naphthalene, compounds other than CO 2 are often obtained. These products, as polymerized polycyclic aromatic hydrocarbons, oxygenated aromatic compounds and benzene derivate compounds, are usually more toxic than naphthalene. At the present work it is shown a nanocrystalline cerium oxide prepared by a combustion method employing a proper ethylene glycol concentration that exhibits very high activity in the decomposition of naphthalene in the presence of air and, most importantly, a selectivity value towards CO 2 of 100% for any range of conversions and/or temperatures used. In addition, it has been demonstrated that the amount of ethylene glycol …

Cerium oxideEthylene GlycolEnvironmental EngineeringHealth Toxicology and MutagenesisInorganic chemistryCatalytic combustionNaphthalenesCatalysisCatalysischemistry.chemical_compoundX-Ray DiffractionEnvironmental ChemistryBenzeneWaste Management and DisposalNaphthalenechemistry.chemical_classificationAir PollutantsAirTemperatureCarbon DioxidePollutionOxygenHydrocarbonchemistryMicroscopy Electron ScanningNanoparticlesGasesSelectivityCrystallizationEthylene glycolJournal of hazardous materials
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Nanocarriers for antioxidant resveratrol: formulation approach, vesicle self-assembly and stability evaluation.

2013

In this work we studied various nanoformulations of resveratrol in phospholipid vesicles. Conventional phophatidylcholine liposomes were prepared and characterized in parallel with PEVs (Penetration Enhancer-containing Vesicles) obtained by adding one of eight selected amphiphilic penetration enhancers (PEs; 0.2% w/v; HLB range 1-16) to the composition. All vesicles were around 100 nm, negatively charged (∼-30 mV) and able to incorporate resveratrol in good yields (>74%). The structure and the lamellar self-organization of the vesicles were investigated by Transmission Electron Microscopy (TEM) and Small and Wide Angle X-ray Scattering (SWAXS). These analyses showed that the lamellarity of …

Chemical PhenomenaDPPHChemistry PharmaceuticalResveratrolAntioxidantschemistry.chemical_compoundColloidColloid and Surface ChemistryDrug StabilityMicroscopy Electron TransmissionPicratesX-Ray DiffractionAmphiphileStilbenesPhysical and Theoretical ChemistryUnilamellar LiposomesLiposomeDrug CarriersChromatographyChemistryVesicleBiphenyl CompoundsSurfaces and InterfacesGeneral MedicinePenetration (firestop)ResveratrolNanoparticlesNanocarriersBiotechnologyColloids and surfaces. B, Biointerfaces
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Influence of Physicochemical Interactions between Amylose and Aroma Compounds on the Retention of Aroma in Food-like Matrices

2002

In food matrices, where starch is often used as a gelling or texturing agent, the occurrence of amylose-aroma complexes and their effect on the release of aroma compounds are difficult to determine. Indeed, thick or gelled systems are known to reduce the diffusion rate of flavor molecules, resulting in an increase of retention. Moreover, interactions between aroma compounds and matrix components might increase the retention of aroma compounds. The complexing behavior of three aroma compounds with amylose was studied by DSC and X-ray diffraction to determine the relative importance of these two factors. Their interaction properties were different: two of them formed complexes, and the third …

Chemical PhenomenaStarchAmylopectinOrganolepticZea mays01 natural scienceschemistry.chemical_compoundViscosity0404 agricultural biotechnologyX-Ray DiffractionAmylose[SDV.IDA]Life Sciences [q-bio]/Food engineeringOrganic chemistryMoleculeComputingMilieux_MISCELLANEOUSAromaFlavorSolanum tuberosumCalorimetry Differential ScanningbiologyChemistry PhysicalViscosity010401 analytical chemistryfood and beveragesStarch04 agricultural and veterinary sciencesGeneral Chemistry[SDV.IDA] Life Sciences [q-bio]/Food engineeringbiology.organism_classification040401 food science0104 chemical scienceschemistryFoodAmylopectinOdorantsThermodynamicsAmyloseGeneral Agricultural and Biological SciencesGelsJournal of Agricultural and Food Chemistry
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