Search results for "YV"

Twisting and buckling: A new undulation mechanism for artificial swimmers

2012

Among the various locomotion strategies of the animal kingdom, the undulation locomotion is of particular interest for biomimetic applications. In this paper, we present an artificial swimmer set into motion by a new and non-trivial undulation mechanism, based on the twisting and buckling of its body. The swimmer consists of a long cylinder of ferrogel which is polarized transversely and in opposite directions at each extremity. When it is placed on a water film and submitted to a transverse oscillating magnetic field, the worm-like swimmer undulates and swims. Whereas symmetry breaking is due to the field gradient, the undulations of the worm result from a torsional buckling instability as…

Robustness, Stability, and Fidelity of Explanations for a Deep Skin Cancer Classification Model

2022

Skin cancer is one of the most prevalent of all cancers. Because of its being widespread and externally observable, there is a potential that machine learning models integrated into artificial intelligence systems will allow self-screening and automatic analysis in the future. Especially, the recent success of various deep machine learning models shows promise that, in the future, patients could self-analyse their external signs of skin cancer by uploading pictures of these signs to an artificial intelligence system, which runs such a deep learning model and returns the classification results. However, both patients and dermatologists, who might use such a system to aid their work, need to …

Designing digital well-being of senior citizens

2020

In this paper, we illustrate a concrete case to apply the Life-Based Design approach to identifying human goals for technology to achieve. We focus on a form-of-life method of design, which seeks to reach a mental state of “digital wellbeing.” Digital well-being aims to facilitate digitalization and changes in the digital environment, and to maximize the availability and accessibility of services. We evaluate the target group of senior citizens, who are facing an accelerating pace of digitalization of the services in their daily lives. This increases their sense of anxiety and undermines their well-being. peerReviewed

Hyvä kuntoutustutkimustyössä : abduktiivinen tutkimus kuntoutustutkimustyön hyväkäsityksellisistä ristiriidoista

2015

The Role of a Supportive Interpersonal Environment and Education-Related Goal Motivation During the Transition Beyond Upper Secondary Education

2018

This longitudinal study investigated the role of parents and peers as well as of education-related goal motivation during educational transitioning in late adolescence. The sample consisted of 1520 upper secondary education students attending either academic or vocational upper secondary school in Finland. They were surveyed three times: (1) in the first year of their upper secondary education, (2) in the second year of their upper secondary education, and (3) two years later. The results show, first, that when students in upper secondary education pursued their educational goals out of autonomous motivation they also invested more effort in their goals, which was reflected in high levels o…

Development of injectable and durable kefiran hydro-alcoholic gels.

2020

Injectable, in-situ forming kefiran gels have been developed for potential applications as implantable drug delivery devices or scaffolds for tissue regeneration. Concentrated solutions (4, 5 and 6%w) of kefiran, extracted from kefir grains, have been assessed in term of viscosity and injectability through G26 syringe needles, and for their ability to undergo gelation upon mixing with different alcohols. Propylene glycol (PG) has been selected as gelling agent because it ensures homogenous gelation in relatively short times (from few minutes up to 6 h). The investigation of the rheological behavior of kefiran/PG gels varying polymer concentration and temperature (25 degrees C and 37 degrees…

Leisure Adjustments of Older Finnish Adults during the Early Stages of the COVID-19 Pandemic

2022

The current approach to “aging well” emphasizes the importance of active leisure participation in late adulthood. This relates to the view that leisure activities enable older adults to stay physically, mentally, and socially active, and they thereby contribute to wellbeing. In spring 2020, leisure activity engagement was significantly hampered by the COVID-19 pandemic. This study explores leisure-related experiences and adaptation strategies among Finnish older adults during the period of strict physical distancing. The data comprises letters (N = 77) written by Finnish people (aged 70–93) that were analyzed using content analysis. The study suggests that the reorganization of leisure was …

Defects in plant immunity modulate the rates and patterns of RNA virus evolution

2020

AbstractIt is assumed that host genetic variability for susceptibility to infection necessarily conditions virus evolution. Differences in host susceptibility can either drive the virus to diversify into strains that track different defense alleles (e.g., antigenic diversity) or to infect only the most susceptible genotypes. To clarify these processes and their effect on virulence, we have studied how variability in host defense responses determine the evolutionary fate of viruses. To accomplish this, we performed evolution experiments with Turnip mosaic potyvirus in Arabidopsis thaliana mutants. Mutant plants had disruptions in infection-response signaling pathways or in genes whose produc…

EXPERIMENTAL EVOLUTION OF AN EMERGING PLANT VIRUS IN HOST GENOTYPES THAT DIFFER IN THEIR SUSCEPTIBILITY TO INFECTION

2014

This study evaluates the extent to which genetic differences among host individuals from the same species condition the evolution of a plant RNA virus. We performed a threefold replicated evolution experiment in which Tobacco etch potyvirus isolate At17b (TEV-At17b), adapted to Arabidopsis thaliana ecotype Ler-0, was serially passaged in five genetically heterogeneous ecotypes of A. thaliana. After 15 passages we found that evolved viruses improved their fitness, showed higher infectivity and stronger virulence in their local host ecotypes. The genome of evolved lineages was sequenced and putative adaptive mutations identified. Host-driven convergent mutations have been identified. Evidence…

Phylogeny of the genus Kluyveromyces inferred from the mitochondrial cytochrome-c oxidase II gene.

2000

A phylogenetic analysis of 17 species belonging to the genus Kluyveromyces and 12 reference and outgroup species was performed using mitochondrial cytochrome-c oxidase II gene sequences. The genus Kluyveromyces appears as a polyphyletic taxon formed by species included within the following four main groups. The Kluyveromyces phaffii group encompasses the species Kluyveromyces blattae, K. phaffii and Kluyveromyces yarrowii. The Kluyveromyces marxianus group is a monophyletic group consisting of the species Kluyveromyces aestuarii, Kluyveromyces dobzhanskii, Kluyveromyces lactis, K. marxianus and Kluyveromyces wickerhamii. The monophyletic Kluyveromyces thermotolerans group is formed by K. th…