Search results for "Zen"
showing 10 items of 3479 documents
Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells
2010
Pancreatic cancer is one of the most aggressive human malignancies with an increasing incidence worldwide. Despite an increase in the number of systemic treatments available for pancreatic cancer, the impact of therapy on the clinical course of the disease has been modest, underscoring an urgent need for new therapeutic options. Although selective cyclooxygenase-2 inhibitors have been demonstrated to have cancer-preventive effects, the mechanism of their effects is not clearly known. Moreover, there have been no unbiased studies to identify novel molecular targets of NS-398 regarding pancreatic cancer. Here we undertook a gene expression profiling study to identify novel molecular targets m…
Identification of lipophilic pollutants discharged from a Finnish pulp and paper mill.
1998
Lipophilic organic compounds originating from kraft pulping and papermaking were identified by straight gas chromatography/mass spectrometry (GC/MS) analyses. Samples analyzed included a primary clarifier effluent (PE) and a secondary clarifier effluent (SE) from the activated sludge treatment plant of a Finnish ECF-bleached (Elementally Chlorine Free) kraft pulp and paper mill. Liquid-liquid extraction composition of PE was compared with solid phase extraction (SPE) and dialysis of a semipermeable membrane device (SPMD) exposed to PE. Dichloromethane extracts of particulate material isolated from PE, sludges from both the primary and secondary clarifier, a sediment collected in the vicinit…
La influencia de Pierre Bayle en la construcción de la segunda antinomia de la razón pura
2020
This paper aims to establish precisely the scope of Pierre Bayle’s influence on the construction of Kant’s second antinomy of pure reason, since there is a remarkable parallelism between this second cosmological conflict and the argument against extension of the article “Zeno of Elea” of Bayle’s Dictionary. It is argued that Bayle, employing the skeptical method in metaphysical research, has a major influence on the construction of the main arguments of the second antinomy and sets a precedent for its logical solution.
Children’s life world as a perspective on their citizenship: The case of the Finnish Children’s Parliament
2012
The latest childhood studies present children’s citizenship as a process of engaging in matters related to children themselves in their everyday lives. However, only a few studies have been conducted on what those issues are and what they actually tell about children’s citizenship. This study explores the nature of children’s participation and citizenship by adopting a life world perspective. The aim is to examine what kind of issues children want to participate in and influence. The data are drawn from an online discussion in the Finnish Children’s Parliament. Altogether 61 children participated in the discussion, with 566 postings. The analysis of the children’s online discussion shows t…
La producción narrativa en el encuentro con la otredad
2020
En este artículo se presenta una investigación basada en una propuesta metodológica que busca el objetivo de dotar de más protagonismo a las participantes en ella a partir del uso de las producciones narrativas como base para la investigación y la transformación social, mediante la creación de un círculo de mujeres de cultura gitana y no gitana. Las producciones narrativas, como herramienta metodológica cualitativa, se basan en el conocimiento local y situado, y se encuentran en relación con lo que experimentamos. La idea central es producir un texto estructurado a partir de la información recopilada por la investigadora durante las sesiones, combinando la observación participativa y la rea…
Exposure to benzene and childhood leukaemia: a pilot case-control study
2013
Objectives Main purpose To evaluate the feasibility of a measurement-based assessment of benzene exposure in case-control studies of paediatric cancer; Additional aims To identify the sources of exposure variability; to assess the performance of two benzene biomarkers; to verify the occurrence of participation bias; to check whether exposures to benzene and to 50 Hz magnetic fields were correlated, and might exert reciprocal confounding effects. Design Pilot case-control study of childhood leukaemia and exposure to benzene assessed by repeated seasonal weekly measurements in breathing zone air samples and outside the children9s dwellings, with concurrent determinations of cotinine, t-t-muco…
Testing the participatory education evaluation concept in a national context
2012
Abstract The article focuses on the realisation of participatory evaluation (PE) in national educational evaluation activity. The realisation of PE is examined by adapting the Daigneault and Jacob model (2009 ; originally Cousins & Whitmore, 1998 ) to five national-level educational evaluations carried out in Finland. According to the chosen frame of reference, self-evaluation regarding the realisation of these five evaluations as well as the analysis of reports that are yielded from the evaluations is used as the research method. PE was realised at a general level in the Finnish national level educational evaluations, but during the process there were considerable differences between the s…
Citizen experts in participatory governance: Democratic and epistemic assets of service user involvement, local knowledge and citizen science
2021
Initiatives that attribute expert status to ‘ordinary citizens’ proliferate in a range of societal realms and are generally celebrated for ‘democratising expertise’. By tapping new sources of knowledge and participation simultaneously, such ‘citizen expertise’ practices seem to provide responses to the contemporary decline of trust in political elites and traditional experts that seriously challenges the legitimacy of democratic policy-making. This study distinguishes between three quintessential types of citizen expertise (‘local knowledge’, ‘service user involvement’ and ‘citizen science’) and, from an integrated perspective, critically discusses the value of citizen expertise for public…
Cómo diseñar talleres para promover la salud en grupos comunitarios
2014
ResumenUna de las estrategias de promoción de la salud es el desarrollo de habilidades para la vida considerando a las propias personas como principal recurso para la salud. Un taller ha de conseguir que sus participantes se conviertan en «activos» para tomar decisiones y generar salud, centrándose en el desarrollo y adquisición de habilidades en grupo de una manera motivadora y con la finalidad de alcanzar unos objetivos. Los conceptos que fundamentan el diseño de un taller y que han de plantearse como etapa 0 son: planificación participativa, capacitar, aprendizaje significativo, aprender en grupo y técnicas participativas.Las etapas que se deben seguir para diseñar un taller y facilitar …
Searches for Sterile Neutrinos with the IceCube Detector
2016
The IceCube neutrino telescope at the South Pole has measured the atmospheric muon neutrino spectrum as a function of zenith angle and energy in the approximate 320 GeV to 20 TeV range, to search for the oscillation signatures of light sterile neutrinos. No evidence for anomalous $\nu_\mu$ or $\bar{\nu}_\mu$ disappearance is observed in either of two independently developed analyses, each using one year of atmospheric neutrino data. New exclusion limits are placed on the parameter space of the 3+1 model, in which muon antineutrinos would experience a strong MSW-resonant oscillation. The exclusion limits extend to $\mathrm{sin}^2 2\theta_{24} \leq$ 0.02 at $\Delta m^2 \sim$ 0.3 $\mathrm{eV}^…