Search results for "Zen"

showing 10 items of 3479 documents

N-(2-Benzoyl-4-chlorophenyl)-4-chlorobenzenesulfonamide

2008

The title compound, C19H13Cl2NO3S, is an N-arylsulfonyl derivative of 2-amino-5-chlorobenzophenone. The compound is biologically active and shows potential to be utilized as an inhibitor of CCR2 and CCR9 receptor functions. In the crystal structure, there is an intramolecular N—H...O hydrogen bond between the amide and carbonyl groups. The benzoyl and 4-chlorophenyl groups form intramolecular and intermolecular face-to-face contacts, with a dihedral angle of 10.6 (1)° between their mean planes in both cases, and centroid–centroid separations of 4.00 (1) and 4.25 (1) Å for the intra- and intermolecular interactions, respectively.

chemistry.chemical_classificationCrystallographyHydrogen bondGeneral ChemistryCrystal structureDihedral angleCondensed Matter PhysicsBioinformaticsOrganic PapersMedicinal chemistrySulfonamidechemistry.chemical_compoundchemistryQD901-999AmideBenzophenoneGeneral Materials ScienceBenzeneDerivative (chemistry)Acta Crystallographica Section E Structure Reports Online
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Optical planar Bragg grating sensor for real-time detection of benzene, toluene and xylene in solvent vapour

2012

Abstract We report on an optical planar Bragg grating sensor functionalized by a comparatively simple method to detect substances such as benzene, toluene and xylene (BTX). The functionalization is performed by allyl substituted γ -cyclodextrin derivatives which are immobilized on the sensor surface by dip coating. Our results prove the capability of this functionalized sensor system to detect lowest concentrations of BTX in solvent vapour in real-time with a sensitivity of 3±0.4 pm/100 ppm for benzene, 8±1 pm/100 ppm for toluene and 32±1 pm/100 ppm for m-xylene. Taking into account the spectral resolution and repeatability of the interrogation system this corresponds to a minimum concentra…

chemistry.chemical_classificationCyclodextrinChemistryXyleneMetals and AlloysAnalytical chemistryCondensed Matter PhysicsTolueneDip-coatingSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsSolventchemistry.chemical_compoundFiber Bragg gratingMaterials ChemistrySurface modificationElectrical and Electronic EngineeringBenzeneInstrumentationSensors and Actuators B: Chemical
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Spectrophotometric determination of binding constants between some aminocyclodextrins and nitrobenzene derivatives at various pH values

2002

Abstract The inclusion capacity of three modified cyclodextrins—namely mono-(6- N , N -dimethylamino-6-deoxy)- ( 3 ), mono-6-(2-aminoethyl)-amino-6-deoxy- ( 4 ) and mono-6-(2- N , N -dimethylaminoethyl)-amino-6-deoxy- ( 5 ) β-cyclodextrin, with six para -substituted nitrobenzenes ( A – F ) has been investigated at three different pH values. Molecular interactions in inclusion complexes have also been investigated by means of molecular mechanics (MM2/QD) models. The desolvation of the cyclodextrin is the most important factor in determining the binding ability of the various hosts. However, for a given host, electrostatic and van der Waals interactions and the formation of a hydrogen bond be…

chemistry.chemical_classificationCyclodextrinHydrogen bondOrganic ChemistrySettore CHIM/06 - Chimica OrganicaBiochemistryBinding constantMedicinal chemistryMolecular mechanicscyclodextrins inclusion molecular mechanicsNitrobenzenesymbols.namesakechemistry.chemical_compoundchemistryComputational chemistryDrug DiscoverysymbolsNon-covalent interactionsDesolvationvan der Waals force
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Determination of optical purity of phosphonic acid analogues of aromatic amino acids by capillary electrophoresis with alpha-cyclodextrin.

2000

A simple and efficient method for the determination of enantiomeric purity of structurally diverse phosphonic and phosphinic acid analogues of phenylalanine and phenylglycine using capillary electrophoresis is presented. These preliminary studies indicated that the enantiomer separation is strongly dependent on the structure of the aminophosphonic acid.

chemistry.chemical_classificationCyclodextrinsalpha-CyclodextrinsChromatographyCyclodextrinOrganic ChemistryOrganophosphonatesElectrophoresis CapillaryPhenylalanineGeneral MedicineBiochemistryAnalytical ChemistryAmino acidchemistry.chemical_compoundCapillary electrophoresischemistryBenzene derivativesAromatic amino acidsphosphonic acidsEnantiomerenantiomer separationAmino AcidsEnantiomeric excessJournal of chromatography. A
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Free energy of solvation of solutes and their partition coefficients in methanol-water binary mixtures

2001

A method is presented that permits semiquantitative estimation of the partitioning of any solute between any two media. The method is adapted to the simulation of multicomponent solvents. As an example, the free energies of solvation ΔG solv,aq o in methanol-water binary mixtures and the partition coefficientsP for organic solvent—aqueous solvent were calculated. The organic solvents studied were 1-octanol, cyclohexane and chloroform. Linear relationships were observed between the relative dielectric constant and the volume fraction of methanol in mixtures with water. The four hydrocarbon models studied were hexane, cyclohexane, hexatriene and benzene. The results are in agreement with calc…

chemistry.chemical_classificationCyclohexaneOrganic ChemistryClinical BiochemistryAnalytical chemistrySolvationBiochemistryAnalytical ChemistryHexaneSolventPartition coefficientchemistry.chemical_compoundHydrocarbonchemistryVolume fractionOrganic chemistryBenzeneChromatographia
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Determination of alkylphenol ethoxylates by micellar electrokinetic chromatography with bile salts

2001

Octyl- and nonylphenol ethoxylates (OPEs and NPEs) with different numbers of ethoxy units (average values: n = 10 and N = 40 for OPEs, and n = 10 for NPEs) were separated by micellar electrokinetic chromatography under positive polarity using an 80 mM borate buffer of pH 8.5 containing sodium deoxycholate (SDC) or sodium cholate (SC). When sodium dodecyl sulfate (SDS) was added to the background electrolyte (BGE) in the absence of the bile salt, a single peak at a migration time longer than that of the EOF was obtained. Substituting the SDS by a bile salt, the homologues were resolved. At the same bile salt concentration, resolution between the homologues was higher with SDC than using SC. …

chemistry.chemical_classificationDetection limitChromatographyAlkylphenolLinear alkylbenzeneClinical BiochemistrySalt (chemistry)BiochemistryMicellar electrokinetic chromatographyAnalytical ChemistryNonylphenolchemistry.chemical_compoundchemistrySodium dodecyl sulfateSodium CholateELECTROPHORESIS
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Allylated cyclodextrins as effective affinity materials in chemical sensing of volatile aromatic hydrocarbons using an optical planar Bragg grating s…

2013

We report on the application of perallyl-substituted α-, β- and γ-cyclodextrins to an optical planar Bragg grating refractive index sensor for the effective sensitization of the sensor for airborne volatile aromatic hydrocarbons. Thereby, the emphasis of this work lies on the comparison of the different cyclodextrin types regarding their suitability as affinity material assessed by the sensors sensitivity and response behavior. The opto-chemical sensor device showed an immediate and quick response to the application of the investigated analytes benzene, toluene and m-xylene as well as a linear dependence on the concentration of those analytes. Studies on the sensors sensitivity depending on…

chemistry.chemical_classificationDetection limitCyclodextrinsVolatile Organic CompoundsAnalyteCyclodextrinAllyl compoundAnalytical chemistryHydrocarbons AromaticBiochemistryTolueneAnalytical ChemistryAllyl Compoundschemistry.chemical_compoundFiber Bragg gratingchemistryEnvironmental ChemistryBenzeneRefractive indexSpectroscopyAnalytica Chimica Acta
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Arynic species II

1986

Abstract o-Benzyne and its 4-methyl, 4-chloro and 4-bromo-derivatives were generated in the thermal decomposition of two new kinds of polymer-bound precursors: 1(2-carboxyaryl)triazenes and 2-carboxyaryl-sulphonates. New kinds of trapping polymers for these elusive species are also presented.

chemistry.chemical_classificationDiazonium CompoundsOrganic ChemistryThermal decompositionLeaving groupReaction intermediateBiochemistryArynechemistry.chemical_compoundBenzylaminechemistryTosylDrug DiscoveryPolymer chemistryOrganic chemistryTriazeneTetrahedron
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Application of Furan as a Diene: Preparation of Condensed 1,3-Oxazines by Retro-Diels−Alder Reactions

2004

(Di-exo-3-amino-7-oxabicyclo[2.2.1]hept-5-en-2-yl)methanol (3) was treated with oxo carboxylic acids [p-toluoylpropionic acid, cis- or trans-(p-toluoyl)cyclohexanecarboxylic acid, -benzoic acid or methanobenzocyclooctenecarboxylic acid] to furnish the oxanorbornene-fused pyrrolo[1,3]oxazine 4, the isoindolo[1,3]oxazines 5 and 6, and the methanobenzocyclooctenepyrrolo[1,3]oxazine 10, together with the retro-Diels−Alder products pyrrolooxazinone 7, oxazinoisoindolones 8 and 9, and oxazinopyrrolobenzocyclooctene 11. On reflux in chlorobenzene, furan was released from the oxanorbornene heterocycles 5 and 10 to give the retro-Diels−Alder products. The structures of the new compounds were establi…

chemistry.chemical_classificationDieneOrganic ChemistryOxazinesNuclear magnetic resonance spectroscopyCyclohexanecarboxylic acidRetro-Diels–Alder reactionchemistry.chemical_compoundchemistryChlorobenzeneFuranOrganic chemistryPhysical and Theoretical ChemistryBenzoic acidEuropean Journal of Organic Chemistry
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Thermal, glass-forming, nonlinear optical and holographic properties of "push-pull" type azochromophores with triphenyl moieties containing isophoren…

2013

Molecular organic compounds with electron donating fragment bounded through π-conjugated system with electron acceptor fragment, as well as with incorporated triphenyl groups in their molecules show potential for creating cheap and simple solution processable materials with nonlinear optical properties. Additional insertion of azobenzene fragment in their structures makes them also possible to form holographic volume and surface relief gratings (SRG) after exposure to laser radiation, which could be useful for holographic data storage. For these purposes polymers are generally used. However, their application is complicated and challenging task as in every attempt to obtain the same polymer…

chemistry.chemical_classificationDiffractionMaterials sciencebusiness.industryPolymerHolographic data storageDiffraction efficiencyAmorphous solidchemistry.chemical_compoundchemistryAzobenzeneOptoelectronicsPhysical chemistryThermal stabilitybusinessGlass transitionSPIE Proceedings
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