Search results for "Zone"

showing 10 items of 2029 documents

Overexpression of Bcl-3 inhibits the development of marginal zone B cells.

2013

The transcription factor Bcl-3 functions as a proto-oncogene via regulation of cell proliferation and apoptosis. Bcl-3 is an atypical member of the IκB family and plays a central role in the immune response through interactions with the NF-κB subunits p50 and p52. To investigate the impact of Bcl-3 on B-cell maturation and regulation, we generated mice that overexpress Bcl-3 specifically in B cells. Interestingly, these mice lack marginal zone B cells and exhibit a significant reduction in the number of B-1 B cells. Further, B cells from these mice are impaired in their proliferative capacity. Our data demonstrate that the overexpression of the transcription factor Bcl-3 inhibits germinal c…

B-LymphocytesCell growthImmunologyGerminal centerGene ExpressionNF-κBBiologyMarginal zoneGerminal CenterMolecular biologyCell biologychemistry.chemical_compoundMiceImmune systemchemistryApoptosisB-Cell Lymphoma 3 ProteinProto-Oncogene ProteinsMarginal zone B-cellImmunology and AllergyAnimalsTranscription factorCell ProliferationTranscription FactorsEuropean journal of immunology
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Seasonal dynamics of biomarkers in infaunal clam Macoma balthica from the Gulf of Riga (Baltic Sea)

2014

Abstract Biomarkers are often regarded as “early warning” signals of environmental pollution; however seasonal changes are mentioned as one of the most important factor that influences the activity of biomarkers. The aim of our study was to assess the importance of seasonal variation of selected contaminant biomarkers in Macoma balthica to provide background information for further environmental surveys in the Gulf of Riga. Seasonal variation of biomarkers (acetylcholinesterase (AChE), catalase (CAT), glutathione reductase (GR) and glutathione- S -transferase (GST)) was measured in infaunal clam M . balthica from the southern part of the Gulf of Riga. The majority of biomarkers (GST, CAT an…

Background informationbiologyEcologyGlutathione reductaseEnvironmental pollutionAquatic ScienceSeasonalityOceanographybiology.organism_classificationmedicine.diseaseSalinityBaltic seaBenthic zonemedicineEcology Evolution Behavior and SystematicsMacoma balthicaJournal of Marine Systems
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Latitudinal- and local-scale variations in a rocky intertidal interaction web

2015

Natural assemblages are structured by a complex combination of positive and negative interactions, and the relative importance of each interaction can vary across spatial scales. By using a simple interaction web (barnacles-grazers-microphytobenthos) in a rocky intertidal system, we tested the hypothesis that the relative strength of positive and negative interactions would vary as a function of different environmental stress between 2 latitudinal levels and local environmental conditions. We manipulated the cover of barnacles and the presence of limpets at 2 sites in northern and southern Italy and non-destructively examined the response of microphyto - benthos (MPB) (photosynthetic biomas…

BarnacleSettore BIO/07 - EcologiaIndirect effectEvolutionIntertidal zoneDensity dependenceBarnacles; Density dependence; Environmental stress; Facilitation; Grazing; Indirect effects; Interaction web; Local stressors; Microphytobenthos; Aquatic Science; Ecology; Ecology Evolution Behavior and SystematicsEnvironmental stressBiologyAquatic ScienceBenthosBehavior and SystematicsInteraction webRelative species abundanceMicrophytobenthoEcology Evolution Behavior and SystematicsTrophic levelAbiotic componentBiomass (ecology)EcologyEcologyEnvironmental streMicrophytobenthosLocal stressorsLocal stressorGrazingIndirect effectsHabitatFoundation speciesFacilitationBarnacles
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Geochemical constraints on basalt petrogenesis in the Strait of Sicily Rift Zone (Italy): Insights into the importance of short lengthscale mantle he…

2020

Igneous activity from the late Miocene to historic time (most recently 1891 CE) in the Strait of Sicily has created two volcanic islands (Pantelleria and Linosa) and several seamounts. These volcanoes are dominated by transitional (ol + hy-normative) to alkaline (ne-normative) basaltic lavas and scoriae; volcanic felsic rocks (peralkaline trachyte-rhyolite) crop out only on Pantelleria. Although most likely erupted through continental crust, basalts demonstrate no evidence of crustal contamination and are geochemically similar to oceanic island basalts (OIB). Despite their isotopic similarities, there are considerable compositional differences with respect to major and trace element geochem…

BasaltContinental-OIBStrait of Sicily Rift ZoneFelsicAlkali Basalt010504 meteorology & atmospheric sciencesContinental crustAlkali basaltKeywords: Strait of Sicily Rift Zone Continental-OIB Alkali basalt Mantle melting Mantle heterogeneitySettore GEO/07 - Petrologia E PetrografiaPartial meltingGeochemistryGeologyCrust010502 geochemistry & geophysics01 natural sciencesMantle (geology)Geochemistry and PetrologyAsthenosphereMantle HeterogeneityMantle MeltingGeology0105 earth and related environmental sciencesChemical Geology
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Accretion of arc-oceanic lithospheric mantle in the Mediterranean: Evidence from extremely high-Mg olivines and Cr-rich spinel inclusions in lamproit…

2007

Abstract Si-rich Mediterranean type lamproites (48–56 wt.% SiO2) are olivine-phyric, mantle-derived volcanics, in which both phenocrystic and xenocrystic olivine are present. Here we demonstrate the phenocrystic origin of the most extremely NiO–MgO enriched olivine in lamproites with Mg# up to 0.95, that host Cr-rich (Cr# around 0.95) spinels. Our comprehensive study of olivine–spinel pairs from Mediterranean lamproites enables us to constrain the extent of depletion of their mantle source. Olivine–spinel pairs from primitive Mediterranean lamproites plot in the most refractory part of the olivine–spinel mantle array diagram, showing even more refractory character than mineral pairs from bo…

BasaltOlivineGeochemistryengineering.materialMantle (geology)GeophysicsSpace and Planetary ScienceGeochemistry and PetrologyUltramafic rockLithosphereHotspot (geology)Transition zoneEarth and Planetary Sciences (miscellaneous)engineeringXenolithGeology
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Brittle reactivation of ductile shear zones in NW Namibia in relation to South Atlantic rifting

2015

Rifting has occurred worldwide along preexisting mobile belts, which are therefore thought to control rift orientation on a large scale. On a smaller scale, shear zones within mobile belts are reactivated as rift faults. In NW Namibia, shear zones of the Neoproterozoic Kaoko Belt run subparallel to the present-day continental passive margin and are inferred to have been reactivated during the opening of the South Atlantic Ocean. However, the extent of this reactivation and the influence of the reactivated shear zones on South Atlantic rifting are largely unknown. A combined remote sensing and field study was conducted to quantify offsets that are a direct function of shear zone reactivation…

BasaltVolcanic rockPaleontologygeographyGeophysicsRiftBrittlenessgeography.geographical_feature_categoryGeochemistry and PetrologyPassive marginShear zoneGeologySeismologyTectonics
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First gas and thermal measurements at the frequently erupting Gamalama volcano (Indonesia) reveal a hydrothermally dominated magmatic system

2020

Abstract The first gas and thermal measurements at the summit of the Gamalama volcano indicate that the system is dominated by hydrothermal processes. This is highlighted by the prevalence of H2S over SO2 (H2S/SO2 = 2–8), a high CO2/SO2 ratio (76–201), and a low heat transfer (3.0 MW) to the surface. A relative variation in gas composition is observed along the degassing fracture zone, possibly due to partial S scrubbing. Despite this surface hydrothermal signature, the system exhibits high gas equilibrium temperatures (425–480 °C), indicating that fluids are not exclusively derived from a boiling hydrothermal aquifer, but also sourced by cooling and crystallizing basaltic magma at deep tha…

Basaltgeographygeography.geographical_feature_category010504 meteorology & atmospheric sciencesGeochemistryDominated hydrothermal systemFracture zoneGeodynamicsGamalama volcano010502 geochemistry & geophysics01 natural sciencesHydrothermal circulationPhreatic eruptionDominated hydrothermal system Gamalama volcano Pressure and tensile strengthGeophysicsVolcanoImpact craterPressure and tensile strength13. Climate actionGeochemistry and Petrology[SDU]Sciences of the Universe [physics]MagmaGeology0105 earth and related environmental sciences
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Crystal size distribution in Jurassic Ferrar flows and sills (Victoria Land, Antarctica): evidence for processes of cooling, nucleation, and crystall…

1996

Jurassic Ferrar rocks in Victoria Land (Antarctica) occur predominantly as basaltic or andesitic flows and sills. Both show characteristic petrographical and chemical variations, which can be related to in-situ differentiation processes. Such characteristics have been investigated at one flow (“Colonnade flow”) and one sill (“Thumb Point sill”) in the Prince Albert Mountains (Central Victoria Land) based on a statistical grain size analysis and the application of the crystal size distribution theory. A third magma body (“HiTi-unit”), which in previous literature was described as a flow, does not show clear similarities to either the flow or sill. Sill and flow are in-situ differentiated wit…

Basaltgeographygeography.geographical_feature_categoryAndesiteAccumulation zoneNucleationSilicicengineering.materialGeophysicsSillGeochemistry and PetrologyMagmaengineeringPlagioclasePetrologyGeomorphologyGeologyContributions to Mineralogy and Petrology
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Sources, degassing, and contamination of CO2, H2O, He, Ne, and Ar in basaltic glasses from Kolbeinsey Ridge, North Atlantic

2005

Abstract New volatile data (CO2, H2O, He, Ne, and Ar) are presented for 24 submarine basaltic glasses from the Kolbeinsey Ridge, Tjornes Fracture Zone and Mohns Ridge, North Atlantic. Low CO2 and He contents indicate that magmas were strongly outgassed with the extent of degassing increasing toward the south, as expected from shallower ridge depths. Ne and Ar are significantly more abundant in the southernmost glasses than predicted for degassed melt. The strong atmospheric isotopic signal associated with this excess Ne and Ar suggests syn- or posteruptive contamination by air. Degassing, by itself, cannot generate the large variations in δ13C values of dissolved CO2 or coupled CO2-Ar varia…

Basaltδ13CGeochemistry and PetrologyHomogeneousGeochemistryFracture zoneContaminationGeologyMantle (geology)Geochimica et Cosmochimica Acta
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Tectono-metamorphic evolution of the pre-Athabasca basement within the Wollaston-Mudjatik Transition zone, Saskatchewan

2016

The Paleoproterozoic tectono-metamorphic evolution of the pre-Athabasca basement (∼1.7 Ga) within the Wollaston–Mudjatik Transition Zone (WMTZ) (Saskatchewan, Canada) has been characterized using both exposed basement and drill cores from the Wolly–McClean exploration drilling project. The finite ductile strain pattern of the WMTZ results from the superposition of two tectono-metamorphic events M1–D1 and M2–D2. M1–D1 is associated with the development of a gently dipping foliation striking N90°–N100° and a southward decrease in peak pressures from up to 10 kbar (1 kbar = 100 MPa) in the Cochrane River area down to 6 kbar in the Wolly–McClean exploration drilling project. The M2–D2 event is…

Basement (geology)010504 meteorology & atmospheric sciencesMetamorphic rockTransition zoneGeochemistryGeneral Earth and Planetary Sciences[SDU.STU]Sciences of the Universe [physics]/Earth Sciences[ SDU.STU ] Sciences of the Universe [physics]/Earth Sciences010502 geochemistry & geophysics01 natural sciencesGeologyComputingMilieux_MISCELLANEOUS0105 earth and related environmental sciences
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