Search results for "aDNA"
showing 5 items of 65 documents
Las competencias básicas en ciencias sociales: trabajo y formación. ¿Un reto para el docente?
2013
En los últimos años una nueva jerga se ha instalado en la didáctica de las Ciencias Sociales. Las Competencias Básicas son presentadas como una innovación educativa donde encontrar soluciones contra el fracaso escolar y aumentar la significancia de los aprendizajes, a la par que la motivación del alumnado. Este estudio analiza cómo trabajan los docentes de Ciencias Sociales de 4º de ESO las Competencias Social-Ciudadana y la Competencia en Comunicación Lingüística. Indagamos por tanto, en la formación del profesorado en Competencias Básicas, sus conocimientos del currículo y las metodologías de aula, a través de un análisis de los contenidos del currículo en relación a estas dos competencia…
Hepatitis B vaccination and interleukin 2 receptor expression in chronic renal failure
1990
Hepatitis B vaccination and interleukin-2 receptor expression in chronic renal failure. Only 50 to 60% of dialysis patients develop anti-HBs antibodies following hepatitis b vaccination. The nonre-sponder state correlates with impaired monocyte function, decreased interleukin-2 (IL-2) production of T cells, and an upregulation of the IL-2 receptor system. In the present study we examined anti-HBs production after hepatitis B vaccination and the in vitro expression of IL-2 receptors in nondialyzed patients with various degrees of chronic renal failure. Forty-four patients with impaired renal function were immunized with 20 µg recombinant hepatitis B vaccine and boostered after one and six mo…
The selective advantage of cystic fibrosis heterozygotes tested by aDNA analysis: A preliminary investigation
2000
Recently a heterozygote advantage was suggested to explain the high incidence (1:25 carrier individuals in Europeans) of the cystic fibrosis gene. This selective advantage was speculated to be due to a high resistance to chloride-secreting diarrhea, including cholera. Up to now the major efforts to test directly this hypothesis have been limited to animal models.
DNA as Building Material at the Nanoscale: From Concepts to Software-aided Design
2017
The affinities of monoclonal antibodies against core antigen of hepatitis B virus
1994
Four monoclonal antibodies generated against the recombinant core antigen of hepatitis B virus are investigated for antigen binding. All exhibit a similar affinity to polystyrene-sorbed antigen but only one of them interacts with native form of HBcAg (an assembled particle) in solution. The presence of 0.1% sodium dodecylsulphate is required for the binding of other three antibodies. The phenomenon can be interpreted as inaccessibility of the corresponding epitopes unless the multimeric antigen structure is disrupted. The core antigen coated on polystyrene is considered as a similar exposed structure.