Search results for "acetate"
showing 10 items of 756 documents
Organic solvent desorption from two tegafur polymorphs.
2013
Desorption behavior of 8 different solvents from α and β tegafur (5-fluoro-1-(tetrahydro-2-furyl)uracil) has been studied in this work. Solvent desorption from samples stored at 95% and 50% relative solvent vapor pressure was studied in isothermal conditions at 30 °C. The results of this study demonstrated that: solvent desorption rate did not differ significantly for both phases; solvent desorption in all cases occurred faster from samples with the largest particle size; and solvent desorption in most cases occurred in two steps. Structure differences and their surface properties were not of great importance on the solvent desorption rates because the main factor affecting desorption rate …
A new dual inhibitor of arachidonate metabolism isolated from Helichrysum italicum.
2003
Six acetophenones (1-6) and one gamma-pyrone (7), previously isolated from Helichrysum italicum, were tested for their ability to inhibit enzymatic and non-enzymatic lipid peroxidation, the stable 1,1-diphenyl-2-pycryl-hydrazyl free radical, superoxide scavenging and arachidonic acid metabolism. In addition, they were studied in different experimental models such as the chronic inflammation induced by 12-O-tetradecanoylphorbol 13-acetate (TPA), the phospholipase A(2)-induced mouse paw oedema test, the carrageenan-induced mouse paw oedema test, and the writhing induced by acetic acid in the mouse. Of the assayed compounds, only 1 inhibited enzymatic lipid peroxidation but had no effect on no…
Antiproliferative activities of resveratrol and related compounds in human hepatocyte derived HepG2 cells are associated with biochemical cell distur…
2008
International audience; Resveratrol is a well known polyphenol largely produced in grapevine. It is a strong antioxidant and a free radical scavenger. It exhibits several beneficial effects for health including cancer. Resveratrol antioxidant activity is essential in the prevention of chemical-induced cancer by inhibiting initiation step of carcinogenesis process but it is also considered to inhibit cancer promotion and progression steps. While the effects of resveratrol on cancer cells are widely described, the data available on the antiproliferative potential of resveratrol derivatives remain weak. Nevertheless, resveratrol analogs could exhibit stronger potentials than the parent molecul…
Gelchromatographie. 8. Mitt.: Vernetzte copolymere des vinylacetats
1969
Die Eigenschaften von vernetzten Copolymeren des Vinylacetats wurden in Abhangigkeit von den Herstellungsbedingungen gepruft. Als Vernetzungsmittel dienten Divinyladipat und Butandiol-(1.4)-divinylather. Mit homogen-vernetzten Gelen konnen Ausschlusmolekulargewichte bis etwa 4000 erzielt werden: zwischen dem spezifischen Gelbettvolumen und dem Ausschlusmolekulargewicht besteht eine lineare Beziehung. Die heterogen-vernetzende Copolymerisation des Vinylacetats in Gegenwart verschiedener inerter Verdunnungsmittel fuhrt zu Gelen mit Ausschlusmolekulargewichten uber 106. Die vernetzten Copolymeren wurden durch ihre scheinbare Dichte, durch die Aufnahme von Losungs- und Fallungsmitteln, durch di…
Oxygenated Cembrene Diterpenes from Sarcophyton convolutum: Cytotoxic Sarcoconvolutum A–E
2021
The soft coral genus Sarcophyton contains the enzymatic machinery to synthesize a multitude of cembrene-type diterpenes. Herein, highly oxygenated cembrenoids, sarcoconvolutum A–E (1–5) were purified and characterized from an ethyl acetate extract of the red sea soft coral, Sarcophyton convolutum. Compounds were assemblies according to spectroscopic methods including FTIR, 1D- and 2D-NMR as well as HRMS. Metabolite cytotoxicity was tested against lung adenocarcinoma, cervical cancer, and oral-cavity carcinoma (A549, HeLa and HSC-2, respectively). The most cytotoxic compound, (4) was observed to be active against cell lines A549 and HSC-2 with IC50 values of 49.70 and 53.17 μM, respectively.
Thermodynamic and kinetic aspects of the transport of small molecules in dispersed systems
1998
Abstract The knowledge of the behaviour of flavour compounds in complex multiphase systems with regard to their structure is of great importance in flavour perception of foods. The thermodynamic and kinetic behaviour of three selected flavour compounds belonging to a homologous series of esters, e.g. ethyl acetate, ethyl butanoate and ethyl hexanoate, were studied in simple and multiphase systems. The liquid system was composed of water (with or without sodium caseinate) and/or a lipid, Miglyol. First, the properties of the solutes were determined by means of their liquid–liquid partition at equilibrium and their diffusion in aqueous or lipid phases. This first step allowed to reveal the im…
Physicochemical Interactions Between Aroma Compounds and Milk Proteins: Effect of Water and Protein Modification
1998
The physicochemical interactions between aroma compounds and sodium caseinate were studied by complementary techniques involving the protein in aqueous solution at 25 or 75 g/L (exponential dilution and equilibrium dialysis) or in a solid state (sorption and infrared spectroscopy). No retention of acetone, ethyl acetate, and 2-propanol in aqueous solutions was found by exponential dilution and equilibrium dialysis. Diacetyl and benzaldehyde interacted with sodium caseinate through strong and weak bonds, as found by equilibrium dialysis. The results obtained by sorption differ from those obtained in aqueous solutions. The compounds that sorbed best to sodium caseinate were acetone and ethyl …
Double-Shell Vesicles, Strings of Vesicles and Filaments Found in Crosslinked Micellar Solutions of Poly(1,2-butadiene)-block-poly(ethylene oxide) Di…
2001
Micellar structures of amphiphilic poly(1,2-butadiene)-block-poly(ethylene oxide) diblock copolymers have been crosslinked in aqueous solution by γ-irradiation. By transmission electron microscopy (TEM) of neganively stained specimen it is shown that the precominant structures present are sopolymer sesicles (which appear to be double latered. These fived vesules are stable with respect to their share and can be transferred from water into a good solvent for blue filbeks, such as tetrahydrofuran, this demonstrating the effectiveness of the crosslinking. In addition to the resicles a small number of flexible cylindrichl/filimented structures sequentially fused vesicles/strings of vesicles and…
Effects of the nature and concentration of substrates in aqueous solutions on the solubility of aroma compounds
2005
The solubility of nine aroma compounds (acetone, 2-butanone, 2-hexanone, 2-octanone, ethyl acetate, ethyl butanoate, ethyl hexanoate, n-hexanal, and n-hexanol) in both water and various aqueous solutions was measured at 25 °C using the mutual solubility method. The aqueous solutions consisted of sucrose, glucose, sorbitol, glycerol, polyethylene glycol 200, or maltodextrins at different concentrations. Aroma solubility in water decreased with increased hydrophobicity. For aroma molecules which have the same number of carbon atoms in their structure, aqueous solubility decreased as follows: aldehyde > methyl ketone > alcohol > ethyl ester. When using a group contribution method, the estimate…
Antibacterial and antifungal activities of Otanthus maritimus (L.) Hoffmanns.Link essential oil from Sicily.
2013
The chemical composition of the essential oil obtained from the flowers of Otanthus maritimus L., a perennial plant growing wild in maritime sands in the Mediterranean region, was investigated by GC and GC-MS analyses. Totally 66 were identified. The oil was dominated by the high content of monoterpene compounds, especially oxygenated monoterpenes which accounted for 73.1%. The most abundant components were yomogi alcohol (20.8%), camphor (15.8%), artemisyl acetate (15.3%) and artemisia alcohol (13.7%). The oil was tested against two Gram (+) and six Gram (-) bacterial strains, both American Type Culture Collection standard strains and clinically isolated (CI), one potentially pathogenic ye…