Search results for "acetate"

showing 6 items of 756 documents

Intra-articular corticosteroids versus intra-articular corticosteroids plus methotrexate in oligoarticular juvenile idiopathic arthritis: a multicent…

2017

Summary Background Little evidence-based information is available to guide the treatment of oligoarticular juvenile idiopathic arthritis. We aimed to investigate whether oral methotrexate increases the efficacy of intra-articular corticosteroid therapy. Methods We did this prospective, open-label, randomised trial at ten hospitals in Italy. Using a concealed computer-generated list, children younger than 18 years with oligoarticular-onset disease were randomly assigned (1:1) to intra-articular corticosteroids alone or in combination with oral methotrexate (15 mg/m 2 ; maximum 20 mg). Corticosteroids used were triamcinolone hexacetonide (shoulder, elbow, wrist, knee, and tibiotalar joints) o…

musculoskeletal diseasesmedicine.medical_specialtyPopulationArthritisInjections Intra-Articular03 medical and health sciences0302 clinical medicineAdrenal Cortex HormonesInternal medicinemedicinemedia_common.cataloged_instanceHumans030212 general & internal medicineProspective StudiesEuropean unionAdverse effecteducationmedia_common030203 arthritis & rheumatologyeducation.field_of_studybusiness.industryMedicine (all)General MedicineMethylprednisolone acetateJuvenile idiopathic arthritismedicine.diseaseArthritis JuvenileSurgeryClinical trialMethotrexateTreatment OutcomeItalySettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAMethotrexateOligoarticular Juvenile Idiopathic Arthritisbusinessmedicine.drug
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Synthesis and Holographic Properties of Alkyl 2-Cyanoacetate Acceptor Fragment Containing Push – Pull Type Organic Glasses

2015

We present synthesis, optical and holographic properties of original structure organic glasses based on compounds consisting of three fragments: of N,N-bis(2-(trityloxy)ethyl)-4-vinylaniline or N,N-bis(5,5,5-triphenylpentyl)-4-vinylaniline fragments as electron donating fragment (D), 4H-pyran-4-ylidene fragment as linker(π) and of 2-(trityloxy)ethyl 2-cyanoacetate or 5,5,5-triphenylpentyl 2-cyanoacetate as acceptor (A) fragment. These push-pull (D- π-A) type molecular compounds show good solubility in non-polar solvents (CHCl3 or CH2Cl2) and neat thin films with sufficient optical qualities have been obtained by spin-coating technique. Maxima of UV–VIS absorption in dichloromethane solution…

organic glassesholographyluminophoresSurface relief gratingsalkyl 2-cyanoacetate darivatives
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CCDC 1938866: Experimental Crystal Structure Determination

2020

Related Article: S. Maryamdokht Taimoory, Kwaku Twum, Mohadeseh Dashti, Fangfang Pan, Manu Lahtinen, Kari Rissanen, Rakesh Puttreddy, John F. Trant, Ngong Kodiah Beyeh|2020|J.Org.Chem.|85|5884|doi:10.1021/acs.joc.0c00220

pyridinium trifluoroacetateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Reactive Compatibilization of PBT/EVA Blends with an Ethylene-Acrylic Acid Copolymer and a Low Molar Mass Bis-Oxazoline

2004

Polyesters and polyolefins form highly incompatible blends with poor properties and gross morphology that hinder any practical applications. In this work, the possibility to compatibilize an incompatible blend of poly(butylene terephthalate) (PBT) with ethylene vinyl acetate (EVA) by adding a bis-oxazoline compound, 2,2'-(1,3-phenylene)-bis(2-oxazoline) (PBO), and an ethylene acrylic acid copolymer (EAA) as compatibilizer precursors has been studied. The results indicate that the binary uncompatibilized blends show poor mechanical properties and a bad morphology with scarce adhesion between the phases. The situation is only slightly improved when the EAA is added while the best performance …

reactive processingMolar massMaterials sciencecompatibilizationPolymers and PlasticsOrganic ChemistryEthylene-vinyl acetateIzod impact strength testCompatibilizationpolymer blendCondensed Matter PhysicsPolyesterchemistry.chemical_compoundSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialichemistryPolymer chemistryMaterials ChemistryCopolymerPolymer blendPhysical and Theoretical ChemistryIonomeroxazolineMacromolecular Chemistry and Physics
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Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.

2003

Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that mediate phospholipase D (PLD) activation in brain, but the mechanism underlying this response remains unclear. Here we used primary cultures of astrocytes as a cell model to explore the mechanism that links mGluRs to PLD. Glutamate activated both phospholipase C (PLC) and PLD with equal potency and this effect was mimicked by L-cysteinesulfinic acid, a putative neurotransmitter previously shown to activate mGluRs coupled to PLD, but not PLC, in adult brain. PLD activation by glutamate was dependent on Ca(2+) mobilization and fully blocked by both protein kinase C (PKC) inhibitors and PKC down-regulation, suggesti…

rho GTP-Binding ProteinsIndolesBacterial ToxinsGlutamic AcidBiologyReceptors Metabotropic GlutamateSulfenic AcidsMaleimidesRats Sprague-DawleyCellular and Molecular NeuroscienceBacterial ProteinsStress FibersmedicinePhospholipase DAnimalsCysteineEgtazic AcidProtein kinase CCells CulturedProtein Kinase CChelating AgentsPharmacologyProtein Synthesis InhibitorsBrefeldin APhospholipase CDose-Response Relationship DrugEndothelin-1Phospholipase DADP-Ribosylation FactorsMetabotropic glutamate receptor 6Glutamate receptorDNAMolecular biologyRatsenzymes and coenzymes (carbohydrates)medicine.anatomical_structureMetabotropic receptorMetabotropic glutamate receptorAstrocytesType C PhospholipasesTetradecanoylphorbol Acetatelipids (amino acids peptides and proteins)AstrocyteNeuropharmacology
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Crystal structure of bis(μ2-methanolato-κO:κO)hexamethylbis(μ2-triphenylacetato-κO:κO′)bis(μ2-triphenylacetato-κ2O,O′:κO)dialuminiumdilanthanum tolue…

2018

The complex [{La(Ph3CCOO)2(Me3AlOMe)}2] has an La2(μ-OCO)4 core, contains the carboxyl­ate ligands in μ2-κ1 O:κ1 O′ bridging and μ2-κ2 O,O′:κ1 O semi-bridging coordination modes, and displays La—C inter­actions with the π-system of a phenyl ring.

triphenylacetatelcsh:Chemistrycrystal structurelanthanumlcsh:QD1-999aluminiumtri­phenyl­acetateπ-complexResearch Communicationscoordination compoundActa Crystallographica Section E: Crystallographic Communications
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