Search results for "actin"

showing 10 items of 1375 documents

Profiling the risk of hepatocellular carcinoma after long-term HCV eradication in patients with liver cirrhosis in the PITER cohort

2023

Background and aims: Severe liver disease markers assessed before HCV eradication are acknowledged to usually improve after the SVR. We prospectively evaluated, in the PITER cohort, the long-term HCC risk profile based on predictors monitored after HCV eradication by direct-acting antivirals in patients with cirrhosis. Methods: HCC occurrence was evaluated by Kaplan-Meier analysis. Cox regression analysis identified the post-treatment variables associated with de-novo HCC; their predictive power was presented in a nomogram. Results: After the end of therapy (median follow-up:28.47 months), among 2064 SVR patients, 119 (5.8%) developed de-novo HCC. The HCC incidence was 1.90%, 4.21%, 6.47% a…

Settore MED/12Real-life cohort.HepatologyDirect-acting antiviral; HCC; Long term outcomes; Predictive factors; Real-life cohortGastroenterologyReal-life cohortLong term outcomeHCCPredictive factorDirect-acting antiviralLong term outcomesPredictive factors
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MICROANASTOMOSI ARTERIOSE CON POLYGLACTIN 910 IN RATTI IN ACCRESCIMENTO

1983

A preliminary issue on effective results of polyglactin 910 as microvascular anastomosis is reported. Tissue reaction to suture material seems to be minor than to prolene or other not absorbible material

Settore MED/20 - Chirurgia Pediatrica E Infantileexperimental microvascular anastomosis polyglactin 910 growing rats tissue reaction.
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Cervico-Facial Actinomycosis: Epidemiological and clinical comments

2008

In a retrospective investigation performed in the department of Surgical Odontostomatology of Palermo University Polyclinic from 1997-2006, the authors examined 12 cases of cervico-facial actinomycosis, taking into consideration age range, gender distribution, predisposing factors and symptoms. In concordance with reports in literature, they found that the disease was perimandibular in 65%, they also report the diagnostic methods and therapeutic approaches used in the study

Settore MED/28 - Malattie OdontostomatologicheSettore MED/08 - Anatomia PatologicaCervicofacial bacterial tumour skin fistula actinomycosis differential diagnosis
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Beliefs and preferences regarding biological treatments for severe asthma

2020

Background: Severe asthma is a serious condition with a significant burden on patients' morbidity, mortality, and quality of life. Some biological therapies targeting the IgE and interleukin-5 (IL5) mediated pathways are now available. Due to the lack of direct comparison studies, the choice of which medication to use varies. We aimed to explore the beliefs and practices in the use of biological therapies in severe asthma, hypothesizing that differences will occur depending on the prescribers’ specialty and experience. Methods: We conducted an online survey composed of 35 questions in English. The survey was circulated via the INterasma Scientific Network (INESNET) platform as well as throu…

Severe asthmaBehavior; Belief; Biological drug; Severe asthmainterleukine 5 IgEMULTICENTERDiseaseOmalizumabADD-ON THERAPYBehavior Belief Biological drug Severe asthmaDOUBLE-BLIND0302 clinical medicineMedicine and Health SciencesImmunology and AllergyEosinophil IL5 [Eos]030223 otorhinolaryngologyPulmonologistssevere asthma biological drug belief behavior3. Good healthBeliefSAFETYmedicine.druglcsh:Immunologic diseases. AllergyPulmonary and Respiratory Medicinemedicine.medical_specialtyEos: Eosinophil IL5ImmunologyBiological drugSpecialtylong-acting beta2-agonist OMASocio-culturaleSettore MED/10 - Malattie Dell'Apparato RespiratorioArticle03 medical and health sciencesQuality of life (healthcare)Omalizumab. OMA/IL5 Omalizumab plus anti-IL5 moleculeOMALIZUMABmedicineIntensive care medicineAsthmaBehaviorINterasma Scientific Network LABAbusiness.industryMEPOLIZUMABmedicine.diseaseEFFICACYICS inhaled corticosteroidsLIFE030228 respiratory systemImmunoglobulin E INESNETAllergistslcsh:RC581-607businessMepolizumab
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Biochemical Responses of European Sea Bass (Dicentrarchus labrax L.) to the Stress Induced by Off Shore Experimental Seismic Prospecting

1999

The paper reports the results of an experimental seismic survey in the open sea by an air gun, carried out to evaluate the effects of air gun acoustic waves on marine animals. Air gun blast exposition was found to have a marked influence on confined Dicentrarchus labrax. Our data, in fact, demonstrated a biochemical response to acoustic stress induced by air gun blasts. Variations of cortisol, glucose, lactate, AMP, ADP, ATP and cAMP in different tissues of D. labrax, indicate that fish have a typical primary and secondary stress response after air gun detonations. Radiography indicates that air gun blasts do not induce any macroscopic effect on skeletal apparatus. The variations of biochem…

Shoregeographygeography.geographical_feature_categorybiologyStress inducedAquatic ScienceOceanographybiology.organism_classificationcomplex mixturesPollutionMediterranean seaOceanographyOpen seaparasitic diseasesEnvironmental scienceFish <Actinopterygii>DicentrarchusSea bassPhysiological valuesMarine Pollution Bulletin
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Ventastega curonica and the origin of tetrapod morphology.

2008

The gap in our understanding of the evolutionary transition from fish to tetrapod is beginning to close thanks to the discovery of new intermediate forms such as Tiktaalik roseae. Here we narrow it further by presenting the skull, exceptionally preserved braincase, shoulder girdle and partial pelvis of Ventastega curonica from the Late Devonian of Latvia, a transitional intermediate form between the 'elpistostegids' Panderichthys and Tiktaalik and the Devonian tetrapods (limbed vertebrates) Acanthostega and Ichthyostega. Ventastega is the most primitive Devonian tetrapod represented by extensive remains, and casts light on a part of the phylogeny otherwise only represented by fragmentary ta…

ShoulderTiktaalikBiologisk systematikVentastegaMorphology (biology)DevoniantetrapodBiological SystematicsBiologyPaleontologyPhylogeneticsevolutionTetrapod (structure)VentastegaAnimalsPelvic BonesBiological sciencesPhylogenyMultidisciplinarypalaeontologyFossilsSkullFishesEvolutionary transitionsbiology.organism_classificationBiological EvolutionFish <Actinopterygii>Nature
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Calcestruzzo autocompattante siciliano: un'esperienza con il filler vulcanico dell'Etna

2009

Self compacting concrete is one of the last developments in the technology of concrete, being studied and improved from the first '70es. Its production is connected with the use of fillers, most of which coming from iron metallurgy, scarsely present on Sicilian territory. So, the aim of the risearch was to realize self compacting concrete using exclusively local filler, particularly the Etna ashes with a strong pozzolanic connotation, pointing out the use of useless at the moment natural resource. The study relates to the verification of the more appropriate mix-designs and the tests on compressive strength of specimens to early curing and after 28 days. Different characterization tests wer…

Sicilian self compacting filler workability strength resistanceSettore ICAR/11 - Produzione Edilizia
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Efficiency of dihydroxamic and trihydroxamic siderochelates to extract uranium and plutonium from contaminated soils

2021

International audience; Actinide-based mineral phases occurring in contaminated soils can be solubilized by organic chelators excreted by plants, such as citrate. Herein, the efficiency of citrate towards U and Pu extraction is compared to that of siderophores, whose primary function is the acquisition of iron(III) as an essential nutrient and growth factor for many soil microorganisms. To that end, we selected desferrioxamine B (DFB) as an emblematic bacterial trishydroxamic siderophore and a synthetic analog, abbreviated (LCy,Pr)H2, of the tetradentate rhodotorulic acid (RA) produced by yeasts. Firstly, the uranyl speciation with both ligands was assessed in the pH range 2–11 by potentiom…

Siderophore010504 meteorology & atmospheric scienceshydroxamic acidHealth Toxicology and Mutagenesis010501 environmental sciencesFerric Compounds01 natural sciencesActinidesSoilchemistry.chemical_compoundRadiation MonitoringEnvironmental Chemistry[CHIM]Chemical Sciencescitratesolid-liquid distributionWaste Management and DisposalEquilibrium constantChemical decomposition0105 earth and related environmental sciences[PHYS]Physics [physics]Hydroxamic acidExtraction (chemistry)General MedicineUranylPollutionPlutoniumRhodotorulic acidchemistryspeciation[SDE]Environmental SciencesUraniumSelectivityNuclear chemistry
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High affinity iron-uptake systems in Vibrio damsela: role in the acquisition of iron from transferrin

1997

In this work, the high affinity iron-acquisition systems displayed by virulent and avirulent strains of Vibrio damsela have been investigated. This species is an autochthonous member of marine ecosystems that can behave as an opportunistic pathogen for fish and mammals. All strains tested (i) were able to grow under the restricted conditions imposed by the iron chelators transferrin (Tf) and EDDHA, (ii) secreted siderophores of hydroxamic type, other than aerobactin and desferal, that were able to stimulate the growth of the auxotroph mutant Arthrobacter flavescens JG9, and (iii) expressed common iron-regulated outer membrane proteins (IROMPs). No change in LPS patterns was observed in resp…

SiderophoreChromatography PaperIronImmunoblottingBiological Transport ActiveSiderophoresVirulenceIron Chelating AgentsApplied Microbiology and BiotechnologyMicrobiologychemistry.chemical_compoundVibrionaceaeVibriochemistry.chemical_classificationVirulencebiologyTransferrinGeneral Medicinebiology.organism_classificationVibriochemistryTransferrinAerobactinElectrophoresis Polyacrylamide GelWater MicrobiologyBacterial outer membraneBacteriaBacterial Outer Membrane ProteinsBiotechnologyJournal of Applied Microbiology
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Siderophores and related outer membrane proteins produced by pseudomonads isolated from eels and freshwater.

1992

A total of 46 environmental pseudomonads, together with six type strains, were examined for their siderophore-producing activity. All strains were able to grow under iron-limiting conditions, gave orange halos in the CAS agar assay, and produced hydroxamates, and some of them also produced phenolate-type compounds. Bioassays showed that all strains, except Pseudomonas aeruginosa, promoted growth of mutant strain Arthrobacter flavescens JG-9, deficient in hydroxamate production, and some of them promoted growth of Salmonella typhimurium enb-1, which requires enterobactin for growth. The presence of iron-regulated outer membrane proteins was observed, the molecular size of the main induced pr…

SiderophoreIronSiderophoresFresh WaterMicrobiologyMicrobiologychemistry.chemical_compoundEnterobactinSpecies SpecificityArthrobacterPseudomonasGeneticsAnimalsMolecular BiologyEelsbiologyPseudomonasbiology.organism_classificationMolecular WeightchemistryMembrane proteinBiochemistryBacterial outer membraneWater MicrobiologyBacteriaPseudomonadaceaeBacterial Outer Membrane ProteinsFEMS microbiology letters
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