Search results for "acute ischemic stroke"

showing 10 items of 24 documents

Cholesterol levels and risk of hemorrhagic transformation after acute ischemic stroke.

2011

<i>Background:</i> The association between cholesterol levels and hemorrhagic transformation (HT) is still controversial. Studies investigating this issue are influenced by treatments as some are characterized by a higher risk of HT. The aim of our study was to evaluate, in a hospital-based series of patients not treated with thrombolysis, the relationship between cholesterol levels and HT. <i>Methods:</i> We retrospectively collected information about total cholesterol (TC) and low-density lipoprotein cholesterol (LDLC) levels at admission in a consecutive series of 240 patients with anterior ischemic stroke (IS). The TC and LDLC levels were arranged in 3 groups acc…

Malemedicine.medical_specialtyDown-RegulationRisk AssessmentBrain Ischemiachemistry.chemical_compoundRisk FactorsCholesterol levels hemorrhagic transformationInternal medicinemedicineOdds RatioHumansRisk factorAcute ischemic strokeAgedRetrospective StudiesChi-Square Distributionbusiness.industryCholesterolCholesterol LDLPrognosisStrokeTransformation (genetics)CholesterolLogistic ModelsNeurologychemistryItalyIschemic strokePhysical therapyCardiologyDisease ProgressionSettore MED/26 - NeurologiaFemaleNeurology (clinical)Cardiology and Cardiovascular MedicinebusinessIntracranial HemorrhagesBiomarkersCerebrovascular diseases (Basel, Switzerland)
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Immuno-inflammatory and thrombotic/fibrinolytic variables associated with acute ischemic stroke diagnosis.

2008

Abstract Introduction Accumulating evidence suggests that inflammation plays an important role in the development of acute cerebrovascular disease. The aim of this study is to evaluate the predictive value of a series of candidate serum immuno-inflammatory and thrombotic/fibrinolitic molecules towards diagnosis of acute ischemic stroke. Materials and methods We enrolled 120 consecutive patients with a diagnosis of acute ischemic stroke and 123 consecutive hospitalized control patients without a diagnosis of acute ischemic stroke. We evaluated plasma levels of IL-1β, TNF-β, IL-6 and IL-10, E-selectin, P-selectin, sICAM-1 and sVCAM-1 as markers of immuno-inflammatory activation, vWF plasma le…

Malemedicine.medical_specialtyPathologySettore MED/09 - Medicina Internamedicine.medical_treatmentImmuno-inflammatory thrombotic/fibrinolytic acute ischemic strokeBrain IschemiaBrain ischemiaPredictive Value of TestsRisk FactorsInternal medicineFibrinolysisstroke inflammation predictive markersmedicineHumansEndothelial dysfunctionStrokeAgedAged 80 and overInflammationVascular diseasebusiness.industryCerebral infarctionFibrinolysisBrainThrombosisMiddle Agedmedicine.diseaseThrombosisStrokeROC CurveImmune SystemPredictive value of testsCardiologyFemaleCardiology and Cardiovascular Medicinebusiness
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Plasma levels of inflammatory and thrombotic/fibrinolytic markers in acute ischemic strokes: Relationship with TOAST subtype, outcome and infarct site

2009

BACKGROUND: The aim of our study was to evaluate in patients with acute ischemic stroke the relationship between immuno-inflammatory variables, clinical outcome and infarct site. MATERIALS AND METHODS: We evaluated plasma levels of IL-1beta, TNF-alpha, IL-6 and IL-10, E-selectin, P-selectin, sICAM-1 ,sVCAM-1 vWF, TPA and PAI-1. RESULTS: Patients with cardioembolic subtype showed significantly higher median plasma levels of TNF-alpha, IL-6, IL-1beta whereas the lacunar subtype showed significantly lower median plasma levels of TNF-alpha, IL-6 and IL-1beta. CONCLUSIONS: A significant association was noted between the severity of neurological deficit at admission, the diagnostic subtype and so…

Malemedicine.medical_specialtystroke TOAST subtypeImmunologyInflammationGastroenterologyBrain IschemiaInternal medicinemedicineHumansImmunology and AllergyIn patientAcute ischemic strokeStrokeAgedNeurological deficitAged 80 and overbusiness.industryFibrinolysisIschemic strokesCerebral InfarctionPlasma levelsMiddle Agedmedicine.diseaseStrokeNeurologyPhysical therapyFemaleNeurology (clinical)Inflammation MediatorsIntracranial Thrombosismedicine.symptombusinessBiomarkersJournal of Neuroimmunology
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Utilization of mechanical power and associations with clinical outcomes in brain injured patients: a secondary analysis of the extubation strategies …

2023

Background: There is insufficient evidence to guide ventilatory targets in acute brain injury (ABI). Recent studies have shown associations between mechanical power (MP) and mortality in critical care populations. We aimed to describe MP in ventilated patients with ABI, and evaluate associations between MP and clinical outcomes. Methods: In this preplanned, secondary analysis of a prospective, multi-center, observational cohort study (ENIO, NCT03400904), we included adult patients with ABI (Glasgow Coma Scale ≤ 12 before intubation) who required mechanical ventilation (MV) ≥ 24 h. Using multivariable log binomial regressions, we separately assessed associations between MP on hospital day (H…

Mechanical powerMechanical ventilationTraumatic brain injuryAcute respiratory distress syndromeAcute ischemic strokeAcute brain injuryIntracranial hemorrhageSubarachnoid hemorrhage
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Polymorphonuclear leukocyte
integrin pattern in acute
ischemic stroke

2001

Polymorphonuclear leukocytePathologymedicine.medical_specialtybiologyVascular diseasebusiness.industryIntegrinIschemiaGeneral Medicinemedicine.diseasePathophysiologyCentral nervous system diseaseNeurologymedicinebiology.proteinNeurology (clinical)businessAcute ischemic strokeStrokeActa Neurologica Scandinavica
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Fluidity and cytosolic Ca2+ concentration of circulating polymorphonuclear leukocytes at baseline in some chronic and acute clinical conditions: revi…

2016

Abstract. Objective: In this mini-review we describe the behavior of polymorphonuclear leukocyte (PMN) membrane fluidity and of PMN cytosolic Ca2+ concentration in some chronic and acute clinical conditions. Methods: PMN membrane fluidity was evaluated employing the fluorescent probe Fura-2AM, and PMN cytosolic Ca2+ concentration was evaluated using the fluorescent probe TMA-DPH. Results: From the determination of these two parameters investigated on resting PMNs, an almost constant increase in PMN cytosolic Ca2+ concentration in chronic clinical conditions, such as vascular atherosclerotic disease with and without diabetes mellitus, essential hypertension, chronic kidney disease, and diabe…

acute ischemic strokemedicine.medical_specialtyClinical BiochemistryCell calciumEssential hypertensionBiochemistryInorganic ChemistryCell calcium; membrane fluidity; fluorescence spectroscopy; polymorphonuclear leukocyte; vascular atherosclerotic disease; diabetes mellitus; chronic kidney disease; essential hypertension; myocardial infarction; acute ischemic strokevascular atherosclerotic diseaseDiabetes mellitusInternal medicineCa2 concentrationmedicineMembrane fluidityMyocardial infarctionAcute ischemic strokePolymorphonuclear leukocytediabetes mellitubusiness.industrymembrane fluiditypolymorphonuclear leukocyteessential hypertensionfluorescence spectroscopymedicine.diseaseCytosolmyocardial infarctionCardiologybusinesschronic kidney disease
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Reduced Admissions for Cerebrovascular Events during COVID-19 Outbreak in Italy

2020

Supplemental Digital Content is available in the text.

disease outbreakMalemedicine.medical_treatment030204 cardiovascular system & hematologyItaly; cerebral hemorrhage; disease outbreaks; incidence; ischemic attack transient0302 clinical medicineEpidemiology80 and overMedicineischemic attack transientThrombolytic Therapy10178Acute ischemic stroke10177ThrombectomyAged 80 and overIschemic AttackTransientIncidence (epidemiology)Endovascular ProceduresMiddle AgedHospitalization1006210183ItalyComputingMethodologies_DOCUMENTANDTEXTPROCESSINGSettore MED/26 - NeurologiaFemaleCardiology and Cardiovascular Medicinecerebral hemorrhage; disease outbreaks; incidence; ischemic attack transient; Italy; Aged; Aged 80 and over; COVID-19; Cerebral Hemorrhage; Endovascular Procedures; Female; Hospitalization; Humans; Ischemic Attack Transient; Ischemic Stroke; Italy; Male; Middle Aged; Thrombectomy; Thrombolytic Therapymedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)RevascularizationSettore MED/261015203 medical and health sciencesHumansAgedIschemic StrokeAdvanced and Specialized Nursingcerebral hemorrhagebusiness.industryOutbreakCOVID-19Emergency medicinedisease outbreaksincidenceBrief ReportsNeurology (clinical)business030217 neurology & neurosurgery
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Cytokines, Selectins and Adhesion Molecules Plasma Levels in Acute Ischaemic Stroke: Relationship with Stroke Subtype, Ischaemic Lesion Site and Clin…

2007

medicine.medical_specialtyCell adhesion moleculebusiness.industryPlasma levelsStroke subtypePharmacotherapyInternal medicineInternal MedicineCardiologyIschemic lesionPhysical therapyMedicineCardiology and Cardiovascular MedicinebusinessAcute ischemic strokeSelectinHigh Blood Pressure & Cardiovascular Prevention
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42 PROGNOSIS OF ACUTE ISCHEMIC STROKE RELATED WITH CARDIOVASCULAR DRUGS TREATMENT DURING HOSPITAL STAY

2008

medicine.medical_specialtyNutrition and Dieteticsbusiness.industryEndocrinology Diabetes and MetabolismMedicine (miscellaneous)medicine.diseaseInternal medicineEmergency medicinemedicineCardiologyCardiology and Cardiovascular MedicinebusinessStrokeAcute ischemic strokeHospital stayNutrition, Metabolism and Cardiovascular Diseases
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Prise en charge de l’infarctus cérébral à la phase initiale

2022

Ischemic stroke accounts for 80% of overall stroke, and is one of the leading causes of death, disability and dementia in worldwide. Management of patients with acute ischemic stroke dramatically improved over time with the implementation of intensive care stroke units, the development of acute recanalization strategies, the optimization of the management of post-stroke complications, and the prevention of early stroke recurrence. The objective of this article is to provide a general overview of the current management of patients with acute ischemic stroke aiming at improving post-stroke outcome.

medicine.medical_specialtyStroke recurrencebusiness.industryGastroenterologyStroke unitsmedicine.diseaseCurrent managementIntensive careEmergency medicineIschemic strokeInternal MedicinemedicineDementiacardiovascular diseasesbusinessStrokeAcute ischemic strokeLa Revue de Médecine Interne
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