Search results for "adaptation"

Local adaptation, coadaptation, and population boundaries

1986

Coadaptation can occur either because of local adaptation in a geographically widespread population and/or because of intrinsic adaptation to the state of other genes or chomosomes. In either event, hybridization between animals with differently coadapted gene or chromosomal complexes can result in a decrease in fertility, viability, etc. in the initial hybrids and especially in later generations. This is known as an outbreeding depression. Moreover, releasing animals not adapted to the local environment can seriously hamper the effectiveness of a reintroduction program, and hybridization can also destroy the local adaptation. Coadapted gene complexes are best detected through studies on na…

Reversible effect of MR and ELF magnetic fields (0.5 T and 0.5 mT) on human lymphocyte activation patterns.

2006

Purpose: The aim of this study was to investigate the effects of magnetic fields (MF) of different intensity generated by a magnetic resonance (MR) unit (0.5 Tesla) and a double cylindrical coil (0.5 mTesla) on human CD4+ T cell lines. Materials and methods: CD4+ T cells were exposed for two hours under isothermal conditions (37 ± 0.5°C) to the above mentioned MF; a control group was provided for each exposed sample. After exposure, the samples were analysed in the laboratory for the following endpoints: Release of cytokines, expression of surface markers, cell proliferation and levels of cytosolic free-calcium. Results: Exposure to MF for 2 h and subsequent in vitro stimulation in the pres…

HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification

2014

Summary The recent HIV-1 vaccine failures highlight the need to better understand virus-host interactions. One key question is why CD8+ T cell responses to two HIV-Gag regions are uniquely associated with delayed disease progression only in patients expressing a few rare HLA class I variants when these regions encode epitopes presented by ∼30 more common HLA variants. By combining epitope processing and computational analyses of the two HIV subtypes responsible for ∼60% of worldwide infections, we identified a hitherto unrecognized adaptation to the antigen-processing machinery through substitutions at subtype-specific motifs. Multiple HLA variants presenting epitopes situated next to a giv…

Prismatic Adaptation as a new tool for non-invasive brain modulation: evidence from different neurophysiological techniques.

Report summarizing the Work Package 4 of the postdoctoral research

2020

The aim of the postdoctoral research programme ‘ARETE school’ was the modernization of general education in Latvian schools, with a focus on character education, by providing research-grounded basis for modelling the ‘Arete school’ programme and scientifically monitoring its piloting and implementation. This report includes information about the organization of the scientific monitoring of the ‘Arete school’ programme, which, following the conclusions of the preliminary research and the recommendations of the mid-term report, was implemented in two steps: 1) scientific monitoring of ‘Arete catalyst’ pilot programme (a teacher training programme for character education); and 2) scientific mo…

Exploiting programmable architectures for WiFi/ZigBee inter-technology cooperation

2014

The increasing complexity of wireless standards has shown that protocols cannot be designed once for all possible deployments, especially when unpredictable and mutating interference situations are present due to the coexistence of heterogeneous technologies. As such, flexibility and (re)programmability of wireless devices is crucial in the emerging scenarios of technology proliferation and unpredictable interference conditions. In this paper, we focus on the possibility to improve coexistence performance of WiFi and ZigBee networks by exploiting novel programmable architectures of wireless devices able to support run-time modifications of medium access operations. Differently from software…

Adaptation of TECCU App Based on Patients´ Perceptions for the Telemonitoring of Inflammatory Bowel Disease: A Qualitative Study Using Focus Groups

2020

Background: Despite the continuous adaptation of eHealth systems for patients with inflammatory bowel disease (IBD), a significant disconnection persists between users and developers. Since non-adherence remains high, it is necessary to better understand the patients&rsquo

L’innovazione tecnologica e il Faculty Development.

2023

La crisi pandemica ha accelerato la diffusione di ambienti di apprendimento caratterizzati dall'uso intensivo della tecnologia. Questa novità rappresenta un obiettivo trasversale della professionalizzazione del docente universitario, con una particolare declinazione sul versante pedagogico-didattico-valutativo quale questione strategica per lo sviluppo dell’alta formazione. Il contributo illustra i risultati di una ricerca condotta con 119 docenti universitari neoassunti e 20 Direttori di dipartimento. La finalità della ricerca è stata, da una parte, rilevare la percezione dei docenti neoassunti relativa alle proprie competenze didattiche, metacognitive e valutative, con riferimento alla di…

Diagrammatic approach to cellular automata and the emergence of form with inner structure

2018

We present a diagrammatic method to build up sophisticated cellular automata (CAs) as models of complex physical systems. The diagrams complement the mathematical approach to CA modeling, whose details are also presented here, and allow CAs in rule space to be classified according to their hierarchy of layers. Since the method is valid for any discrete operator and only depends on the alphabet size, the resulting conclusions, of general validity, apply to CAs in any dimension or order in time, arbitrary neighborhood ranges and topology. We provide several examples of the method, illustrating how it can be applied to the mathematical modeling of the emergence of order out of disorder. Specif…

Membrane fluidity of stressed cells of Oenococcus oeni

2000

International audience; The determination of membrane fluidity in whole cells of Oenococcus oeni was achieved by membrane probe 1,6-diphenyl-1,3,5-hexatriene fluorescence anisotropy measurements. The results demonstrated instantaneous fluidity variations with cells directly stressed during the measure. Heat (42°C) or acid (pH 3.2) shocks decreased the anisotropy values (fluidising effects), whereas an ethanol shock (10% ethanol, v/v) increased the membrane rigidity. The velocities of fluidity variation with non-adapted or adapted cells (incubation in inhibitory growth conditions) were compared. The adaptation of the cells to acid conditions had no effect on the membrane fluidity variation a…