Search results for "adem"
showing 10 items of 1337 documents
EPCT-15. RAPID EPIGENOMIC CLASSIFICATION OF BRAIN TUMORS ENABLES INTRAOPERATIVE NEUROSURGICAL RISK MODULATION
2021
Abstract Background Clear identification of tumor subtype is the main predictor of patient outcome and ultimately what is considered an adequate level of surgical risk. At brain tumor resection, imaging modalities and intraoperative histology often give an ambigious diagnosis, complicating intraoperative surgical decision-making. Here, we report a nanopore DNA methylation analysis (NDMA) sequencing approach combined with machine learning for classification of tumor entities that could be used intraoperatively. Methods We analyzed 50 biopsies obtained from biobanked tissue (43, prospective) or sampled at surgery (7, intraoperative) from 20 female and 30 male patients with a median age of 8 y…
Valodas izvēle tirdzniecības zīmēs
2017
Valoda ir nozīmīga ikdienas komunikācijas daļa. Uzņēmēji to izmanto, lai paustu savus biznesa mērķus un idejas. Viens no svarīgākajiem kompānijas aspektiem ir tās zīmola attēls; tā ir pirmā lieta, kas reprezentē kompāniju un ļauj tai tikt uztvertai kā labam pakalpojuma sniedzējam potenciālo klientu acīs. Lai zīmols būtu juridiski aizsargāts, tam ir jābūt reģistrētam kā tirdzniecības zīmei. Pētījuma mērķis ir noskaidrot, kādus lingivistiskos un paralingvistiskos līdzekļus pakalpojumu sniedzēji Baltijas valstīs izmanto tirdzniecības zīmēs. Lai veiksmīgi veiktu pētījumu, tika analizētas 45 tirdzniecības zīmes, kuras ir reģistrētas Baltijas valstu Patentu iestādēs. Gandrīz visas analizētās tird…
Computational identification of cell-specific variable regions in ChIP-seq data.
2019
ABSTRACT Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is used to identify genome-wide DNA regions bound by proteins. Several sources of variation can affect the reproducibility of a particular ChIP-seq assay, which can lead to a misinterpretation of where the protein under investigation binds to the genome in a particular cell type. Given one ChIP-seq experiment with replicates, binding sites not observed in all the replicates will usually be interpreted as noise and discarded. However, the recent discovery of high-occupancy target (HOT) regions suggests that there are regions where binding of multiple transcription factors can be identified. To investigate these regions,…
Longitudinal associations of student–teacher relationships and behavioural and emotional strengths on academic achievement
2017
Positive student–teacher relationships are related to students’ academic achievement and behavioural and emotional adjustment. How a student’s behavioural and emotional strengths are associated with these relationships and how the relationships influence students’ academic performance remains unknown. We examined this framework using a cross-lagged panel model with a group of Finnish students and their parents from Grade 5 to Grade 7. The results revealed that the parents rated behavioural and emotional strengths are stable over a 1-year (r = .78) and 2-year (r = .71) period and that students’ perceptions of student–teacher relationships demonstrated greater change over time (r’s = .54, .35…
Physical, Psychological and Sexual Abuse of the Minor in the Families from the Northwestern Region of Romania- Social and Medical Forensics
2020
Background: In Romania, the abuse within the family of the minor child is a widespread phenomenon, its extent is insufficiently known because of ignorance/not reporting all the existing cases.
 Methods: The participants of the research are represented by two independent groups from the NW Romania 2007-2011, one for sociological study (1544 parents and 1283 children) and another for forensic statistical study (2761 cases of abused children). The sociological study was carried out by analyzing questionnaires applied in schools located in Bihor County, both to children and parents. The statistical analysis was carried out by studying the cases of the physically, sexually, and psychologica…
Molecular biology, China and the West
2000
More than 15 years ago, in November 1985, I travelled to China for the first time. I joined a symposium on developmental biology in the Shanghai Institute of Cell Biology (CBI), organised by the Chinese Academy of Sciences and the Max‐Planck‐Gesellschaft in Germany. The symposium was meant to provide perspectives for the future of the Max Planck Guest Laboratory, just founded in the CBI. When I attended, I did not anticipate that my visit to Shanghai would initiate a long‐term commitment to China. I did not even expect to return to China in the near future. But early in 1987, my colleague Uli Schwarz from the Max Planck Institute of Developmental Biology in Tubingen, who was and still is in…
Un texto académico del ocaso del siglo XVII: el "Discurso sobre el microscopio" de José Ortí y Moles (Estudio y edición)
2010
El Discurso sobre el microscopio del Dr. José Ortí Moles (1650-1728) es el texto de una conferencia impartida en Valencia a finales del siglo XVII. Su autor un conocido jurista, dramaturgo y poeta fue invitado por alguna de las academias a las que perteneció ¿del Conde de la Alcudia? ¿Valenciana? a disertar sobre un tema que supuestamente dominaba como amateur. La exposición superficial, obsoleta, sesgada hacia la metáfora político-moral y basada en la obra de los jesuitas PP. Kircher, Schott y Milliet Dechales nos proporciona un magnífico testimonio del estado de conocimientos y del grado de aspiraciones intelectuales alcanzado por las academias valencianas de notables. (A)
Todos a la derecha
2007
Carboxylated-xyloglucan and peptide amphiphile co-assembly in wound healing.
2021
Abstract Hydrogel wound dressings can play critical roles in wound healing protecting the wound from trauma or contamination and providing an ideal environment to support the growth of endogenous cells and promote wound closure. This work presents a self-assembling hydrogel dressing that can assist the wound repair process mimicking the hierarchical structure of skin extracellular matrix. To this aim, the co-assembly behaviour of a carboxylated variant of xyloglucan (CXG) with a peptide amphiphile (PA-H3) has been investigated to generate hierarchical constructs with tuneable molecular composition, structure, and properties. Transmission electron microscopy and circular dichroism at a low c…