Search results for "aged"

showing 10 items of 17367 documents

Eight new mutations and the expanding phenotype variability in muscular dystrophy caused by ANO5.

2012

Objective: Description of 8 new ANO5 mutations and significant expansion of the clinical phenotype spectrum associated with previously known and unknown mutations to improve diagnostic accuracy. Methods: DNA samples of 101 patients in 95 kindreds at our quaternary referral center in Finland, who had undetermined limb-girdle muscular dystrophy (LGMD), calf distal myopathy, or creatine kinase (CK) elevations of more than 2,000 IU/L, were selected for ANO5 genetic evaluation, and the clinical findings of patients with mutations were retrospectively analyzed. Results: A total of 25 patients with muscular dystrophy caused by 11 different recessive mutations in the ANO5 gene were identified. The …

myalgiaMalePathologymedicine.disease_causeCohort Studies0302 clinical medicineMedicineMuscular dystrophyAge of OnsetCreatine KinaseFinland0303 health sciencesMutationMuscle WeaknessbiologyMiddle AgedPhenotypeMagnetic Resonance Imaging3. Good healthPhenotypeFemalemedicine.symptomAdultmedicine.medical_specialtyWeaknessGenotypeBlotting WesternAnoctaminsGenes RecessiveAsymptomatic03 medical and health sciencesChloride ChannelsHumansGenetic TestingMyopathyMuscle Skeletal030304 developmental biologyAgedbusiness.industryGenetic VariationReproducibility of ResultsDNAmedicine.diseaseMuscular Dystrophies Limb-GirdleMutationbiology.proteinCreatine kinaseNeurology (clinical)business030217 neurology & neurosurgeryNeurology
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Hypokalemic rhabdomyolysis associated with Bartter's syndrome.

1983

Severe potassium deficiency is an uncommon cause of rhabdomyolysis. We recently treated a 45-year-old patient with myalgia, serious generalized weakness, increased serum creatine kinase and myoglobin level as well as excessive hypokalemia. Histological examination of deltoid muscle biopsy showed rhabdomyolysis. After complete recovery of muscle damage by potassium substitution Bartter's syndrome proved to be the cause of initial and persistent hypokalemia.

myalgiaMalemedicine.medical_specialtyendocrine system diseasesHypokalemiaurologic and male genital diseasesGastroenterologyNecrosisInternal medicineDeltoid muscleDrug DiscoveryBiopsyHyperaldosteronismmedicineHumansCreatine KinaseGenetics (clinical)Histological examinationmedicine.diagnostic_testbusiness.industryMyoglobinMusclesMyoglobinuriaBartter SyndromeGeneral MedicineMiddle Agedmedicine.diseaseHypokalemiaBartter's syndromeAnesthesiaPotassiumMolecular MedicinePotassium deficiencymedicine.symptombusinessRhabdomyolysisKlinische Wochenschrift
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Associations of physical performance and physical activity with mental well-being in middle-aged women

2021

Abstract Background To investigate whether physical performance is independently of physical activity (PA) associated with positive and negative dimensions of mental well-being in middle-aged women. Methods Data were drawn from the Estrogenic Regulation of Muscle Apoptosis (ERMA) study in which women 47 to 55 years were randomly selected from the Finnish National Registry. They (n = 909) participated in measurements of physical performance (handgrip force, knee extension force, vertical jumping height, maximal walking speed, and six-minute walking distance). Both mental well-being (the Centre for Epidemiologic Studies Depression Scale, the International Positive and Negative Affect Schedule…

naisetaffektiivisuusPhysical performance0302 clinical medicinedepressive symptomsPositive affectivityBayesian multivariate linear regressionEpidemiology030212 general & internal medicineFinlandmiddle-age women030219 obstetrics & reproductive medicineHand StrengthDepressionDepressive symptomsMiddle AgedPhysical Functional Performancekeski-ikäisetMental HealthPositive affectivityMarital statuspositive affectivityaerobinen suorituskykyFemaleLife satisfactionPublic aspects of medicineRA1-1270Clinical psychologyResearch Articlemasennusmedicine.medical_specialtyNegative affectivityNegative affectivity03 medical and health sciencesAerobic capacitymedicineHumanslife satisfactionExerciseMiddle-age womensuorituskykybusiness.industryPublic Health Environmental and Occupational HealthLife satisfactionphysical performancenegative affectivityPreferred walking speedaerobic capacityCross-Sectional StudiestyytyväisyysBiostatisticsbusinessBMC Public Health
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Electrocardiographic predictors of six-minute walking distance among 63-76-year-old women

2006

naisetelectrocardiographythe agedtestitcardiovascular diseasessix-minute walking testkuntotestitEKGhuman activitiesikääntyneet
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Decreasing muscle performance associated with increasing disease activity in patients with rheumatoid arthritis

2018

Objectives Increasing evidence suggests that inflammation has a detrimental effect on muscle strength. Our objective was to analyse the association between muscle performance and different disease activity levels in patients with rheumatoid arthritis (RA). Method A total of 199 consecutive outpatients were subject to cross-sectional assessment. Measurements of grip strength, endurance of the upper and lower limbs and trunk strength were combined as a muscle performance composite score (MPCS), using a standardised method. The disease activity for 28 joints (DAS28), radiographs of small joints (Larsen score), rheumatoid factor, body mass index (BMI), comorbidities and anti-rheumatic drugs wer…

nivelreumarheumatoid arthritisMaleINACTIVITYArthritislcsh:MedicineMuscle ProteinsComorbidityBiochemistrySeverity of Illness IndexArthritis RheumatoidGrip strength0302 clinical medicineRisk FactorsSTRENGTHCACHEXIAMedicine and Health SciencesCRITERIAPublic and Occupational Health030212 general & internal medicinelcsh:ScienceMusculoskeletal SystemINDEXPain Measurement2. Zero hungerMultidisciplinaryMusclesWOMENta3141Muscle AnalysisMiddle AgedSports Science3. Good healthBioassays and Physiological AnalysisRheumatoid arthritisStrength TrainingFemaleBONE-MINERAL DENSITYAnatomylihaskuntoResearch Articlemedicine.medical_specialtymuscle fitnessStrength trainingHEALTHY CONTROLSImmunologyRheumatoid ArthritisResearch and Analysis MethodsAutoimmune Diseases03 medical and health sciencesRheumatologyInternal medicineHand strengthmedicineRheumatoid factorHumansMuscle StrengthRisk factorSports and Exercise MedicineMuscle SkeletalExercise030203 arthritis & rheumatologybusiness.industryArthritislcsh:RENERGY-EXPENDITUREBeck Depression InventoryBiology and Life SciencesProteinsPhysical Activitymedicine.diseaseJoints (Anatomy)PHYSICAL-ACTIVITYCross-Sectional StudiesSkeletal MusclesPhysical Fitness3121 General medicine internal medicine and other clinical medicinemuscle strengthPhysical Endurancelcsh:QClinical ImmunologyClinical MedicinebusinesslihasvoimaPLoS ONE
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Etiological factors of chronic hepatitis in Italy: a 2014 national survey.

2017

Background The last Italian prevalence survey on chronic hepatitis (CH) conducted in 2001 showed that the hepatitis C virus (HCV) was the main agent associated with CH. Aim The aim of this study was to evaluate epidemiological changes in CH occurring after 13 years. Patients and methods Enrollment of 1392 CH consecutive patients referred to 16 Italian liver units in 2014 scattered all over the country (four in the North, four in the Center, four in the South, and four in the Islands) was performed. Results The mean age of the patients was 58.3 years, with a sex ratio (male/female) of 1.5. HCV infection (also with other etiologies) continues to be the most prevalent etiology (58.1%). However…

nonalcoholic fatty liver diseaseAdultMalemedicine.medical_specialtyPediatricsTime FactorsTime FactorAdolescentHepatitis C virusmedicine.disease_causemetabolic syndrome03 medical and health sciencesYoung Adult0302 clinical medicinechronic hepatitiRisk FactorsEpidemiologyNonalcoholic fatty liver diseasemedicinePrevalenceHumansAgedHepatitis ChronicHepatitisAged 80 and overHepatologybusiness.industryRisk FactorGastroenterologyEntecavirHepatitis CHealth SurveyHepatitis BHepatitis C ChronicMiddle Agedmedicine.diseaseHealth SurveysItaly030220 oncology & carcinogenesisEtiology030211 gastroenterology & hepatologyFemalehepatitis C virus infectionbusinessHumanmedicine.drugEuropean journal of gastroenterologyhepatology
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A four-session acceptance and commitment therapy based intervention for depressive symptoms delivered by masters degree level psychology students: a …

2013

Background:Depressive symptoms are one of the main reasons for seeking psychological help. Shorter interventions using briefly trained therapists could offer a solution to the ever-rising need for early and easily applicable psychological treatments.Aims:The current study examines the effectiveness of a four-session Acceptance and Commitment Therapy (ACT) based treatment for self-reported depressive symptoms administered by Masters level psychology students.Method:This paper reports the effectiveness of a brief intervention compared to a waiting list control (WLC) group. Participants were randomized into two groups: ACT (n= 28) and waiting list (n= 29). Long-term effects were examined using…

noviceAdultMalemedicine.medical_specialtyAdolescentPsychological interventiontherapistPilot Projectsbehavioral disciplines and activitiesAcceptance and commitment therapySession (web analytics)brief interventionTreatment and control groupsdepressive symptomsIntervention (counseling)medicineHumansPsychologyAcceptance and Commitment TherapyPsychiatryStudentsta515AgedDepressionBeck Depression InventoryFlexibility (personality)General MedicineMiddle AgedClinical PsychologyTreatment OutcomeFemaleBrief interventionPsychologyClinical psychologyBehavioural and cognitive psychotherapy
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Inequalities in Adolescent Health and Life Satisfaction : Evidence from the Health Behaviour in School-Aged Children Study

2016

nuorettyytyväisyysterveyskäyttäytyminenschool-aged childreneriarvoisuusphysical activityadolescentslife satisfactionterveysbalanced diet
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Diet to Reduce the Metabolic Syndrome Associated with Menopause. The Logic for Olive Oil

2020

The rates of metabolic syndrome are increasing in parallel with the increasing prevalence of obesity, primarily due to its concomitant insulin resistance. This is particularly concerning for women, as the years around menopause are accompanied by an increase in visceral obesity, a strong determinant of insulin resistance. A fall in estrogens and increase in the androgen/estrogen ratio is attributed a determining role in this process, which has been confirmed in other physiological models, such as polycystic ovary syndrome. A healthy lifestyle, with special emphasis on nutrition, has been recommended as a first-line strategy in consensuses and guidelines. A consistent body of evidence has ac…

obesityMediterranean dietmedicine.drug_classmenopausePhysiologylcsh:TX341-641030209 endocrinology & metabolismReviewDisease030204 cardiovascular system & hematologyDiet Mediterraneanmetabolic syndromeHealthy Aging03 medical and health sciences0302 clinical medicineInsulin resistanceHumansMedicineNutritional Physiological PhenomenaHealthy LifestyleAgedNutrition and Dieteticsbusiness.industryEstrogensMiddle Agedolive oilmedicine.diseasePolycystic ovaryObesityMenopauseEstrogenObesity AbdominalAndrogensFemalewomenDiet HealthyInsulin ResistanceMetabolic syndromehealthy ageingbusinesslcsh:Nutrition. Foods and food supplyFood ScienceNutrients
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Heritability of anterior chamber depth and axial length: a population-based twin study among 66 to 79-year old female twins.

2014

ocular refractionAnterior ChamberInheritance PatternsPopulation basedBiologyheritabilityRefraction Ocular03 medical and health sciences0302 clinical medicineTwins DizygoticInheritance PatternsHumansGene–environment interaction030304 developmental biologyAgedGenetics0303 health sciencesGeneral MedicineAxial lengthta3142Twins MonozygoticHeritabilityTwin studyta3125OphthalmologyAxial Length Eye030221 ophthalmology & optometryFemaleGene-Environment InteractionDemographyActa ophthalmologica
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